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cds.ahrq.gov/taxonomy/term/14896
November 02, 2018 - Search All AHRQ Sites
Careers
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cds.ahrq.gov/cdsconnect/artifact/recommendation-11-concurrent-use-opioids-and-benzodiazepines
September 27, 2018 - Search All AHRQ Sites
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www.ahrq.gov/sites/default/files/wysiwyg/professionals/quality-patient-safety/patient-safety-resources/resources/advances-in-patient-safety/vol1/French.pdf
April 27, 2004 - Outpatient Benzodiazepine Prescribing, Adverse Events, and Costs
185
Outpatient Benzodiazepine Prescribing … Benzodiazepine Prescribing and Adverse Events
193
Table 5. … Association of road-traffic accidents with
benzodiazepine use. … Benzodiazepine
tranquilizers and the risk of accidental injury. … Benzodiazepines and
injury: a risk adjusted model.
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psnet.ahrq.gov/issue/association-between-concurrent-use-prescription-opioids-and-benzodiazepines-and-overdose
March 07, 2018 - Study
Association between concurrent use of prescription opioids and benzodiazepines … Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective … Concurrent use of opioids and benzodiazepines increases risk for adverse drug events . … Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective … An electronic intervention to improve safety for pain patients co-prescribed chronic opioids and benzodiazepines
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psnet.ahrq.gov/issue/patterns-outpatient-benzodiazepine-prescribing-united-states
June 23, 2010 - Study
Patterns in outpatient benzodiazepine prescribing in the United States. … Patterns in Outpatient Benzodiazepine Prescribing in the United States. … This observational study based on surveillance data documents increasing rates of benzodiazepine prescribing … The rate of coprescription of benzodiazepines with opioids and other sedating medications has also … Patterns in Outpatient Benzodiazepine Prescribing in the United States.
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www.ahrq.gov/news/newsletters/e-newsletter/764.html
May 01, 2021 - Prescription Rates of Dental Benzodiazepines Higher in the United States Than Other Countries
Issue … study published in the American Journal of Preventive Medicine found that dental benzodiazepine prescriptions … Dentists may use benzodiazepines to manage patient anxiety before a procedure. … Benzodiazepine prescribing is often associated with polydrug abuse and can lead to significant substance … This study was the first to offer an international comparison of benzodiazepine prescriptions.
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psnet.ahrq.gov/issue/effect-pharmacist-email-alerts-concurrent-prescribing-opioids-and-benzodiazepines-prescribers
September 07, 2022 - Study
Effect of pharmacist email alerts on concurrent prescribing of opioids and benzodiazepines … Effect of pharmacist email alerts on concurrent prescribing of opioids and benzodiazepines by prescribers … Concurrent prescribing of opioids and benzodiazepines can put patients at increased risk of overdose … Effect of pharmacist email alerts on concurrent prescribing of opioids and benzodiazepines by prescribers … 2021
Balancing safety, comfort, and fall risk: an intervention to limit opioid and benzodiazepine
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www.ahrq.gov/patient-safety/settings/long-term-care/resource/injuries/fallspx/manapb22.html
December 01, 2017 - for Further Assessment and/or Interventions
Medications
Antipsychotics
Antidepressants
Benzodiazepines … Parkinson's disease
Dementias and delirium
Dizziness
Depression
Drugs
Antipsychotics
Antidepressants
Benzodiazepines
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digital.ahrq.gov/ahrq-funded-projects/tools-optimizing-medication-safety-top-meds/citation/benzodiazepine-opioid-co
January 01, 2022 - Benzodiazepine-opioid co-prescribing in a national probability sample of ED encounters. … Benzodiazepine-opioid co-prescribing in a national probability sample of ED encounters.
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srdr.ahrq.gov/projects/592/studies/81861
January 01, 2010 - Cancel
Study Preview
Study Title and Description
Is there a role for benzodiazepines … 0 ) |
Post/View
Title Data
Title
Is there a role for benzodiazepines
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psnet.ahrq.gov/issue/electronic-intervention-improve-safety-pain-patients-co-prescribed-chronic-opioids-and
May 11, 2011 - An electronic intervention to improve safety for pain patients co-prescribed chronic opioids and benzodiazepines … An electronic intervention to improve safety for pain patients co-prescribed chronic opioids and benzodiazepines … This study describes an electronic intervention to identify patients coprescribed opioids and benzodiazepines … The intervention significantly reduced the proportion of patients coprescribed opioids and benzodiazepines … February 28, 2018
Electronic medical record alert associated with reduced opioid and benzodiazepine
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psnet.ahrq.gov/sites/default/files/2023-07/spotlight_a_complicated_course.pdf
January 01, 2023 - • He was treated with symptom-triggered dosing of benzodiazepines utilizing the
CIWA protocol and … • Benzodiazepines (BZDs) are the mainstay of therapy in AWS and are the only class of
medication with … • ASAM recommends use of dexmedetomidine as an adjunct to benzodiazepine therapy to
control autonomic … continuous infusions of short-acting BZDs
versus dexmedetomidine.13
– The dexmedetomidine group showed a benzodiazepine … This effect may worsen
progression of AWS, if benzodiazepines are not adequately administered.
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cds.ahrq.gov/sites/default/files/cds/artifact/136331/Benzodiazepine%20Patient%20Handout.pdf
January 01, 2018 - PowerPoint - Updated Handouts - Read-Only
REDUCING MEDICATIONS SAFELY
TO MEET LIFE’S CHANGES
FOCUS ON BENZODIAZEPINE … RECEPTOR AGONISTS (BZRAs)FOCUS ON BENZODIAZEPINE RECEPTOR AGONISTS & Z-DRUGS (BZRAs)
As life changes … Evidence-based clinical
practice guideline for deprescribing benzodiazepine receptor agonists. … Adapted from “Reducing Medications Safely to Meet Life’s Changes, Focus on Benzodiazepine Receptor Agonists
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cds.ahrq.gov/sites/default/files/cds/artifact/476/Pilot%20Site%20Training%20for%20Pain%20Management%20Summary%20CDS%20for%20Repository.pdf
May 24, 2023 - preferred
– ≥90 MME/day is high risk
§ Urine drug screening (prior to and annually)
§ Avoid concurrent benzodiazepines … Assessments
§ MME amount - most recent
§ Urine drug screen results – all within the past 1 year
§ Benzodiazepine … ”
§ Benzodiazepine Medications
– Elements: Benzodiazepine medication statements and orders.
– Flag … if there is at least one benzodiazepine medication and at least one opioid medication:
“Benzodiazepine … ”
– Flag if there is at least one benzodiazepine medication: “Evidence of a benzodiazepine medication
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/anxiety-adults-screening
June 20, 2023 - Case-control studies found an association between benzodiazepine use and suicide death 85 and spontaneous … One included study found an association between use of benzodiazepine for treatment of anxiety and higher … US Food and Drug Administration (FDA) issued a warning:
…even when taken at recommended dosages, [benzodiazepine … Benzodiazepines versus placebo for panic disorder in adults. … FDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class: includes potential
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psnet.ahrq.gov/web-mm/medication-safety-events-related-diagnostic-imaging
January 26, 2022 - Patient Safety
Opioids and benzodiazepines are commonly used medications in the acute care setting … In the United States, over half of hospitalized patients receive opioids and 48% receive benzodiazepines … . 2,3 Opioids and benzodiazepines can be beneficial; however, their respiratory depressant effects are … Concurrent opioid and benzodiazepine use is associated with a two-fold increase in all-cause mortality … Benzodiazepine pharmacology and central nervous system-mediated effects.
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digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/simon-sr-et-al-2006
January 01, 2006 - targeted potentially inappropriate medication (e.g., tertiary tricyclic amine antidepressants, long-acting benzodiazepines … "From November 2000 through December 2002, the EHR employed drug-specific alerts for long-acting benzodiazepines … Clinician ordered one of the target medications [tertiary tricyclic amine antidepressants, long-acting benzodiazepines
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cds.ahrq.gov/sites/default/files/cds/artifact/476/Pilot%20Site%20Training%20for%20Pain%20Management%20Summary%20CDS_for%20Repository.pdf
September 21, 2018 - preferred
– ≥90 MME/day is high risk
▪ Urine drug screening (prior to and annually)
▪ Avoid concurrent benzodiazepines … – Stool softeners and laxatives
Risk Considerations
– MME amount
– Urine drug screen results
– Benzodiazepine … ”
▪ Benzodiazepine Medications
– Elements: Benzodiazepine medication statements and orders. … – Flag if there is at least one benzodiazepine medication and at least one opioid medication:
“Benzodiazepine … ”
– Flag if there is at least one benzodiazepine medication: “Evidence of a benzodiazepine medication
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psnet.ahrq.gov/web-mm/complicated-course-severe-alcohol-withdrawal-dexmedetomidine-infusion
June 14, 2023 - Benzodiazepines (BZDs) are the mainstay of therapy in AWS and are the only class of medication with … ASAM recommends use of dexmedetomidine as an adjunct to benzodiazepine therapy to control autonomic hyperactivity … and anxiety when these symptoms are not well controlled by optimized dosing of benzodiazepines alone … continuous infusions of short-acting BZDs versus dexmedetomidine. 13 The dexmedetomidine group showed a benzodiazepine … This effect may worsen progression of AWS, if benzodiazepines are not adequately administered.
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effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - However, we did find that
the IV was associated with the use of long-acting benzodiazepines. … Long-
acting benzodiazepines are not recommended for use in the
elderly as they have been associated … of which 530 (18.6%) were for
a long-acting benzodiazepine. … This is likely to be a
result of long-acting benzodiazepines being indicated for
certain psychiatric … Benzodiazepines of long and short
elimination half-life and the risk of hip fracture.