- 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
April 01, 2013 - and other comparators used to 
categorize risk as insignificant/indolent or aggressive predict the behavior … This can 
be based on biopsy findings that suggest 
aggressive versus indolent tumor behavior, 
such … Missed tumors should 
exhibit the same or more indolent behavior than those identified by testing; the … of prostate cancer and what is 
learned through the studies in Research 
Question 2.1 about likely behavior … Modeling allows predictions of outcomes 
from use of PCA3 based on logical 
assumptions of tumor behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
December 01, 2011 - AHRQ Healthcare Horizon Scanning System  
 
 
Horizon Scanning Protocol and Operations Manual 
 
 
Prepared for:  
Agency for Healthcare Research and Quality 
U.S. Department of Health and Human Services 
540 Gaither Road 
Rockville, MD 20850 
www.ahrq.gov 
 
Contract No. HHSA290201000006C 
 
Prepared by: 
… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
August 01, 2016 - Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings
B A C K G R O U N D
Alcohol use disorder (AUD) includes harmful use of alcohol, 
alcohol abuse, and alcohol dependence. In the fifth edition of the 
Diagnostic and Statistical Manual of Mental Disorders (DSM-5), 
alcohol abuse and alcohol de… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - A Randomized Trial of Epidural Glucocorticoid Injections for Spinal Stenosis: A Brief Summary of Findings for Clinicians
A Randomized Trial of Epidural Glucocorticoid 
Injections for Spinal Stenosis: A Brief Summary 
of Findings for Clinicians
KEY CLINICAL ISSUE 
What are the relative effectiveness and adverse effect… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
June 01, 2015 - services, adherence to therapy, missed appointments, patient 
self-management, and changes in health behavior … of Care
• Adherence to therapy
• Missed appointments
• Patient self -management
• Change in health behavior … services, adherence to therapy, missed appointments, patient 
self-management, and changes in health behavior … of Care
• Adherence to therapy
• Missed appointments
• Patient self -management
• Change in health behavior … missions or focuses (e.g., focus on 
preventing major events like hospitalization 
versus supporting behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - amino 
acid.1  This abundance of Phe may cause intellectual disability, delayed speech, seizures, 
and behavior … in adolescent girls with 
PKU is also difficult because they are not always monitored for high-risk behavior … tissues; […this results in] mental retardation, microcephaly, delayed speech, seizures, 
eczema, behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
January 01, 2000 - Study Eligibility Criteria
Study Eligibility Criteria
Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Methods Guide for Effectiveness and Comparative Effectiveness Reviews
Study Eligibility Criteria
Systematic Review Process Overview
*
Systematic Review Process Overview
This slide illu… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/advanced-care-decision-aids_research-protocol.pdf
December 09, 2013 - advanced-care-decision-aids-protocol-131209
 
  
     
 
 
   
   
        
        
  
 
  
 
     
 
 
 
  
 
 
 
 
    
 
 
 
  
  
   
 
 
 
  
   
    
 
   
     
   
   
 
Evidence-based Practice Center
 
Technical Brief Protocol
 
Project Title: Decision Aids for Advanced Care Planning… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - glaucoma drugs was used to control for potential bias because statin users engage in more health-seeking behaviors … prevents bias from arising from prevalent users being long-term adherers who may also follow other healthy behaviors … bias is challenging and may only be achieved in observational studies when (1) information on health behaviors
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
October 25, 2010 - Source: www.effectivehealthcare.ahrq.gov  
Published Online: July 12, 2011 
1 
Evidence-based Practice Center Systematic Review Protocol 
 
Comparative Effectiveness of Multidisciplinary Postacute Rehabilitation for 
Moderate to Severe Traumatic Brain Injury in Adults 
 
I. Background and Objectives for the System… 
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
January 01, 2012 - distribution of multiple diagnoses in chronic pelvic pain
related to previous abuse or drug-seeking behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-indicators-symposium_research.pdf
April 01, 2010 - include: coping with emotions associated with cancer and its 
treatment; managing the illness; changing behaviors
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-mental-health_research.pdf
January 01, 2017 - al., 20125 
No No NA Not a traditional 
clinical trial in that it 
focused on changing 
clinician behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
July 01, 2012 - Methods Guide for Medical Test Reviews Chapter 10
10-1 
Chapter 10 
 
Deciding Whether To Complement a Systematic 
Review of Medical Tests With Decision Modeling  
 
Thomas A. Trikalinos, M.D., Tufts Evidence-based Practice Center, Boston, MA 
Shalini Kulasingam, Ph.D., University of Minnesota School of Public He… 
                                     
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-protocol.pdf
July 10, 2018 - ("alternative medicine" or acupuncture or "animal assist*" or art or "cell phone" or "cognitive 
behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
March 29, 2013 - mothers who are depressed.4 
Depression during pregnancy is known to lead to harmful prenatal health behaviors … Efficacy/ Effectiveness Outcomes 
Maternal 
•	 Danger to self (suicidal and nonsuicidal behaviors) … •	 Danger to infant (infanticidal behavior, abuse, or neglect) 
•	 Depression symptomatology as scored
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol.pdf
July 10, 2018 - ("alternative medicine" or acupuncture or "animal assist*" or art or "cell phone" or "cognitive 
behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_executive.pdf
May 01, 2013 - of 
health care; functional and quality-of-life outcomes such as 
speech and language development, behavior … Studies reported 
mixed findings for behavior outcomes at less than 1 year 
(insufficient strength of … evidence); three studies reporting 
behavior at more than 1 year reported no difference (low 
strength … Low for no 
difference
3 RCTs (N=710) No difference in behavior at 1 year or more.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - bowel-affecting drugs: anticholinergics (hyoscyamine sulfate), tricyclic 
agents (amitriptyline, imipramine) 
o Behavior … o Reduced severity of incontinence (volume and type of leakage; the use of coping 
behaviors): multiple … .): FIQL subscales,25 Euro-QoL 5D (anxiety/depression 
subscale)35 
o Change (reduction) in coping behaviors … Life (FIQL, HRQoL) 
Continence measures 
Urgency 
Pain 
Social activity 
Sexual function 
FI coping behaviors … Stool Neurogenic Mixed Unknown 
PFMT      
Biofeedback      
Diet      
Medications (by type)      
Behavior
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_disposition-comments.pdf
January 01, 2013 - been effective in helping clients 
address substance abuse issues, as well as 
criminal and HIV risk behavior