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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - Dosing instructions has not frequently been
assessed as a barrier and therefore it should not be included … Although we list difficulty taking medication as a barrier that has
been studied, in the table of barriers … suggest that there are multiple barriers that could offset the
adherence improvement, yet only one barrier
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effectivehealthcare.ahrq.gov/sites/default/files/asthma-self-mgmt-summary.pdf
April 01, 2020 - Technical Brief No. 35, Characteristics of Existing Asthma Self-Management Education Packages - Summary
What is the purpose of this
Technical Brief?
To examine key components of asthma self-
management education (AS-ME) packages, evaluate
available research on AS-ME effectiveness, and
improve underst…
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effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
December 01, 2015 - wider use of surveillance for Barrett’s
esophagus.24,25 According to one clinical expert, another barrier … procedure in a
6
primary care provider’s office, noted one research expert.29 Another possible barrier … Although access to any
care might still present a barrier, these populations might have better access
-
effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
January 01, 2012 - The upfront costs of the device and implantation procedure are
significant, and may pose a barrier … suggested that the infusion method of administration and required frequent office visits could be a
barrier
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/strategies-integrating-behavioral-health-protocol.pdf
August 04, 2022 - Strategies for Integrating Behavioral Health and Primary Care
1
Evidence-based Practice Center Systematic Review
Protocol
Project Title: Strategies for Integrating Behavioral Health and Primary Care
I. Background and Objectives for the Systematic Review
Background
Behavioral health is an umbrell…
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
February 01, 2015 - central nervous system via the olfactory and trigeminal neural pathways,
bypassing the blood-brain barrier … Intranasal delivery
bypasses the blood-brain barrier to target
therapeutic agents to the central
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effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
June 01, 2014 - crypt cell
proliferation; inhibiting crypt cell apoptosis (programmed cell death); and enhancing gut barrier … Experts listed cost as a barrier to adoption, but also noted the
potential to reduce home-care costs
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-education-protocol.pdf
January 01, 2018 - Research Protocol: Characteristics of Existing Asthma Self-Management Education Packages
1
Evidence-based Practice Center
Technical Brief Protocol
Project Title: Characteristics of Existing Asthma Self-Management
Education Packages
I. Background and Objectives for the Technical Brief
Asthma is a ch…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
January 01, 2014 - Unlike ERT products, miglustat can cross the blood-brain
barrier . . .
a. … The FDA‐approved product label does not give details
regarding miglustat crossing the blood‐brain barrier … contain
recommendations for chaperone therapy with ERT based on
miglustat crossing the blood/brain
barrier … previous paragraph that
states “In theory, SRTs also have the potential to cross the blood
brain barrier … The following sentence was added to page 37, third
paragraph: “For example, the blood-brain barrier
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effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
December 05, 2013 - favorable outcomes, third-party
reimbursement will be more likely, they thought, which would remove the barrier … This lack of payer coverage appears to be the largest barrier to acceptance and
diffusion because of … of multilevel disc replacement as investigational by third-party payers may present a
significant barrier … The largest barrier to patient acceptance would be
reimbursement, noted two health systems experts.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
June 01, 2013 - to show favorable outcomes, third-party
reimbursement might be more likely, which would remove the barrier … Lack of payer coverage appears to be the largest barrier to acceptance and
diffusion because of high … of multilevel disc replacement as investigational by third-party payers may present a
significant barrier … However, they noted the need for bone
marrow harvest could be a significant barrier to patient acceptance
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - widely by both patients and clinicians for the targeted population, but noted cost to be a
major barrier … Experts thought lack of long-term safety and efficacy data was the
most significant barrier to otherwise … adopted widely
by both patients and clinicians for the target population, but noted cost to be a major barrier … Several experts
listed cost as a major barrier for patient and clinician acceptance, but noted that … present a
significant disruption.”83
Health disparities: Several experts cited cost as a major barrier
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effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - Several experts mentioned the uncertainty of long-term adverse
events as a potential barrier to patient … experts agreed that the idea of inhibiting absorption in the intestine using an explantable
impermeable barrier … would be involved
in learning the implantation procedure, but did not think it would be a significant barrier
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - by
patients and clinicians alike, the experts generally agreed; however, some listed cost as a
barrier … The company initially had a limited distribution system, posing a major, initial barrier to
diffusion … clinicians prescribing Qsymia for their
eligible patients.”52 But experts also noted a potential barrier … training on how to properly self-inject the drug, but
they did not anticipate this issue to be a barrier … However, several experts list cost to be a potential barrier to
patient acceptance.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - (Krystexxa) for treatment of chronic gout
adverse events was seen as a potentially significant barrier … The
need for IV administration was also identified as a barrier for patients. … This may also serve as a barrier to clinician
acceptance due to concerns over disease transmission.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2021.pdf
January 01, 2021 - AHRQ's Evidence-based Practice Center Division Annual Report 2021: Solving the Puzzle for Evidence-Based Decision Making
e
AHRQ’s Evidence-based
Practice Center Division
Annual Report 2021
Solving the Puzzle for Evidence-Based
Decision Making
1
Solving the Puzzle for Evidence-Based
Decision Making
Evidence
N…
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effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Some experts also thought clinician
acceptance might be a barrier to adoption because the technology … acceptance, at least at first, may not be universal.”18 Several experts cited
cost as a potential barrier … care that prevent access, although lack of
access to computer technology and the Internet would be a barrier
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-health-systems-guidelines-development.pdf
February 01, 2019 - Experts also cited the volume of data in tables as a barrier, as well as the perception that the data … One interviewee mentioned the density of some of
the literature as a barrier.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
August 18, 2011 - operate on
an acute care model that fails to engage patients in their own care and thus serves as a barrier
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
December 01, 2014 - crypt cell
proliferation; inhibiting crypt cell apoptosis (programmed cell death); and enhancing gut barrier … Experts listed cost as a barrier to adoption but also
noted the potential to reduce home-care costs