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effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
March 01, 2012 - Power Calculations for Superiority RCTs for Various 5-year Primary Event Rates in
the Comparator Arm … Power calculations for superiority RCTs for various 5-year primary event rates in the
comparator arm11 … Plotted are power calculations for six different 5-year primary event rates in the comparator arm … Noncomparative Study
Examples of this design include:
A study that presents a description of a … Terms associated with study designs
Term Description
Cluster The term cluster refers to a unit of
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effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_disposition-comments.pdf
January 28, 2016 - introduction to the main
body as well as the background of the executive
summary should qualify the description
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effectivehealthcare.ahrq.gov/products/mental-illness-outcomes/research-protocol
March 03, 2014 - Among adults with an SMI in 2008, less than 60 percent used any mental health services in the past year … What are potential long-term (10-year) developments in this field?
Methods
1. … Specifically, our responses to GQs 1 (description and definition of QMs in SMI), 2 (context for use of … The following information will be obtained from each study, where applicable: author, year of publication … Amendments
In the event of protocol amendments, the date of each amendment will be accompanied by a description
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
May 08, 2013 - These have been added to the description. … about the exclusion of
other systematic reviews which
looked at comparative treatments
that the author … The author is an ex-Board member
of NPUAP. Summary: The rate of
closure was 50% at 4-weeks. … This
author also recognized that 'more
recently developed pressure-
relieving systems might be cost … Thus,
for a clinical problem that may
costs 11 billion dollars a year, we
need evidence of what works
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
March 03, 2014 - Among adults with an SMI in 2008, less than 60 percent used any mental health services in the
past year … What are potential long-term (10-year) developments in this field?
III. Methods
1. … Specifically, our responses to GQs 1 (description … applicable: author … Amendments
In the event of protocol amendments, the date of each amendment will be accompanied by a
description
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
January 08, 2024 - Details of included studies
Author, Year Study Design Country Setting/Transition Adult, Adolescent, … facility (mean stay 30 to 45 days) Adolescent Inclusion:
Caregiver: 1) Legal guardian of a 12 to 17-year-old … the diary, space for text/graphical diary entries, list of terms used frequently in the ICU, and a description … Duration: 3 days
Followup: 1 year NR Readmissions A vs. … test not reported)
Pilot unit in hospital experienced reduction from 28.2% at baseline to 14% at 1-year
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - for non-inferiority; 1.7% per year vs.
2.2% per year for rivaroxaban and warfarin,
respectively; HR … Excellent description of
results. … Rates were: 0.26% per year for rivaroxaban vs.
0.44% per year for warfarin. … Rates were: 0.04% per year for
rivaroxaban vs. 0.19% per year for warfarin. … Rates were: 1.53% per year for
rivaroxaban vs. 1.71% per year for warfarin.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
February 25, 2014 - Multiple SAMHSA reports based on annual,
representative household face to face surveys each year from … We contacted the author for clarification of the number of
participants but did not receive a response … The evaluation covered year 1-2. … We contacted the author for clarification of the number of
participants but did not receive a response … I am unaware of any inappropriate inclusions
or exclusions, and, as a co-author of one of the studies
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_disposition-comments.pdf
October 07, 2012 - Introduction On page iii of the ES, stakeholders are mentioned, but then I did not find an explicit
description … Peer Reviewer #9 Methods Page ES-8, L 56: Need some description of PICOTS. … ExSumm and table 7 of the body for Key Question 2 it would be very
helpful for me if you listed the Author … Added study author and year to these
tables. … Peer Reviewer #5 Discussion Implications are clearly stated but there is not a sufficient description
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_disposition-comments.pdf
July 26, 2012 - A detailed
description is provided in Appendix F. … qualitative studies, which
includes the interviews and descriptive surveys,
has now been ordered by year … Author of paper, or EPC report authors? … 1) The text has been revised to clarify that this is
the conclusion of the author of the paper. 2) … First author – consider having
consistency of details throughout report.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
November 01, 2013 - of the project or fiscal year of funding. … When trying to contact a study
19
author, there is little guidance as to how many times this … reviewers conducted by Mullan, et al.84 reported that most
respondents contacted at least one study author … Trying to contact one study author three times and other
study authors once is systematically different … FDA Web Site – Drugs@FDA
Agency URL Description
U.S.
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effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - The outcomes and
description of harm types were also clear and
sensible. … The most notable shortcoming was the
lack of a detailed description of the meta-analytic
models. … We have added this as well as more description
of the methods (in Appendix G). … sub-group effects, or were
removed for the various sensitivity analyses; we
have added the study author … TEP 5 Discussion Good description of the limitations of the CER. What
and why were explained.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - The outcomes and
description of harm types were also clear and
sensible. … The most notable shortcoming was the
lack of a detailed description of the meta-analytic
models. … We have added this as well as more description
of the methods (in Appendix G). … sub-group effects, or were
removed for the various sensitivity analyses; we
have added the study author … TEP 5 Discussion Good description of the limitations of the CER. What
and why were explained.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_disposition-comments.pdf
March 21, 2013 - See Woolcock 2008; Fraser
and Critchley 2007; Munro and Critchley 2011
A description of terminology … Peer Reviewer #7
(TEP)
Introduction
p. 4 l.13-14 l. 23
This is too simplistic a description of … Line 23 “encourage
endometrial quiescence” and “prevent growth” are the type of
description I would … Results
p. 26 l. 25
There is a RCT from Scandanavia comparing LNG-IUS with
hysterectomy with 5+ year … This may not have been
captured, but it is RCT with followup beyond a year.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - After studies are screened and determined to meet inclusion criteria, we will abstract study
design, year … Data Synthesis:
Characteristics of included studies, such as number of publications by year, study sample … Author
2. Year of publication
3. Bibliographic citation
4. PubMed ID
5. … Year of publication
2. Study class
3. Country/Countries of study sites
4. Site type
5. … Treatment Description
4.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
November 12, 2020 - Additions to risk of bias template
Rater Author, Year Selection Bias Domain: Randomization Adequate? … Center
ROB Risk of bias
RTI-UNC RTI-UNC Evidence-based Practice Center
NOTE: Each column includes a description
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
November 12, 2020 - Additions to risk of bias template
Rater Author, Year Selection Bias Domain: Randomization Adequate? … Center
ROB Risk of bias
RTI-UNC RTI-UNC Evidence-based Practice Center
NOTE: Each column includes a description
-
effectivehealthcare.ahrq.gov/products/renal-update/research-protocol
January 20, 2015 - effectiveness reviews, and will include elements that address population characteristics including description … between the comparative groups or overall high loss to follow-up, and the validity and adequacy of the description … descriptions of the study design, intervention(s), mean baseline blood pressure and kidney function, description
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
February 01, 2012 - We added a description of myxedema coma
Source: http://www.effectivehealthcare.ahrq.gov/index.cfm … UPdate...nearly 1 year old). … Introduction p. 14, line 43--on the third review, state number and type of studies We have added this description … As noted above, these two studies are
problematic and there is no evidence to support a 1-2 year
observation … We removed the “1-2 year” from
the sentence
Peer Reviewer
#6
Results Table 10AB is great, except
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
December 14, 2012 - Public Seidenfeld Background P 1 Relative 5-year survival rate
Since estimates for stage I and across … However, in the
description of studies excluded from the literature review on page 11 the
authors state … (Beginning) There is a description of the GEPs. … The 5-year distant-metastasis free survival was
95% for low risk patients and 80% for high risk patients … The 3-year RFS
was 91% for Low Risk and 74% for High Risk patients with a HR of 2.9
(p=0.001).”