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281. The Effect of Protein Intake on Health (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
     November 29, 2023 - on the amount of protein intake (e.g., only the type of protein or source of protein reported) Assessment … Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of eligible RCTs by outcomes … An assessment of high indicates strong confidence that the estimate of effect lies close to true effect … An assessment of insufficient indicates no evidence was located, and we were unable to estimate an … Assessment of Methodological Risk of Bias of Individual Studies E. Data Synthesis F.

282. Treatment of Stage I-III Squamous Cell Anal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-protocol.pdf
     September 26, 2023 - Assessment of Methodological Risk of Bias of Individual Studies We will assess risk of bias of eligible … Because these organizations use Grading of Recommendations Assessment, Development and Evaluation ( … Because these organizations use Grading of Recommendations Assessment, Development and Evaluation … Making an overall rating of confidence in effect The strength of evidence assessment will clearly … Assessment of Methodological Risk of Bias of Individual Studies E. Data Synthesis F.

283. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
     October 27, 2017 - /evaluation Instruments Clinical tools and individual risk factors for assessment/ evaluation … We will apply this outcome-specific quality assessment to groups of outcomes that have lower risk of … In brief, the approach requires assessment of five domains: study limitations (previously named risk … We will use a checklist to guide the assessment of applicability. … QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.

284. Machine Learning Tools To (Semi-)Automate Evidence Synthesis: A Rapid Review and Evidence Map, Version 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/white-paper-machine-learning-tools-v2.pdf
     July 01, 2025 - Risk of bias assessment tools showed moderate agreement with human assessments (Cohen’s kappa = 0.20 … Results of studies assessing RobotReviewer for original Cochrane RoB assessment tool .............. … 17101, 110-125 (11) Human assessment or assessment in the published review Cohen's weighted … Language models for data extraction and risk of bias assessment in complementary medicine. … Analysis of Extracted Data 3.2.7 Risk of Bias Assessment Tools 4. Discussion 4.1.

285. Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
     January 01, 2024 - coordinated with NCPTSD have included adding newly published RCTs, some additional data elements, and RoB assessment … with comprehensive data, calculated standardized effect sizes for continuous PTSD outcomes, and RoB assessment … Inclusion of RoB assessment using the same scale for all studies and standardized effect sizes allows

286. Assessing Applicability | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-applicability/slides

287. Anxiety in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
     September 12, 2016 - Patient centered outcomes: § Remission, relapse, anxiety symptoms, behavioral problems (Behavior Assessment … college graduate) § Family dysfunction/stressor: • Parenting Stress Index (PSI) • Brief Family Assessment … Assessment of Methodological Risk of Bias of Individual Studies We will evaluate the risk of bias of … Based on this assessment and the initial study design, we will assign a strength of evidence rating … Practice parameter for the assessment and treatment of children and adolescents with anxiety disorders

288. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Neuropsychiatric Interpretive Electroencephalograph Assessment Aid (NEBA) for assessment of attention-deficit … Eligible Topic Not Deemed High Impact  The Neuropsychiatric Interpretive Electroencephalograph Assessment … Food and Drug Administration in July 2013 as a clinician evaluation–adjunct assessment tool. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form.

289. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - symptoms)  Scores are combined to give a global assessment (0: No RLS; 1-10: mild; 11-20: moderate … Blinding is a key component of assessing overall quality because assessment of treatment effectiveness … We anticipate that studies may report dichotomous outcomes (e.g., global assessment of improvement) … In brief, the EPC approach requires assessment of four domains for each outcome:  Risk of bias ( … A 10-year, longitudinal assessment of dopamine agonists and methadone in the treatment of restless

290. Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients during Clinical Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/clinical-care-protocol.pdf
     January 01, 2024 - We will not perform an independent assessment of original studies cited in any such systematic review … Risk of Bias Assessment For studies that address the Review Question about the effectiveness of programs … Error disclosure: a new domain for safety culture assessment. … We will not perform an independent assessment of original studies cited in any such systematic review … Data Extraction Risk of Bias Assessment Data Synthesis Analysis of Subgroups or Subsets Registration

291. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of eligible studies will … If the risk of bias assessment tool is similar to our approach, we will separately assess risk of bias … QUADAS-2: A revised tool for the quality assessment of diagnostic accuracy studies. … Uncertain Question Response Criteria Justification Internal Validity Overall Assessment Overall … Risk of Bias assessment Low Results are believable taking study limitations into consideration

292. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
     May 22, 2012 - Assessment of Methodological Quality of Individual Studies We will assess methodological quality, or … We will use a checklist to guide the assessment of applicability. … Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological treatment … QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies. … Methods “Assessment of Methodological Quality,” 1st paragraph, 1st 2 sentences We will assess

293. ADHD-Update-protocol-160818 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
     August 18, 2016 - ADHD Diagnosis: ADHD diagnosis is normally based on physician assessment to determine whether the patient … Assessment of these final outcomes is challenging because they can be related to the negative outcomes … We will use a checklist to guide the assessment of applicability. … Neuropsychiatric Electroencephalograph-Based Assessment Aid (NEBA). … Assessment. 2008;15(3):317-28. PMID: 18310593. 22. Conners CK, Pitkanen J, Rzepa S.

294. Acs-Pci-Adjunctive-Devices Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
     April 01, 2013 - Opinion We shared the conclusions of the original report with two experts in the field for their assessment … Original conclusion is out of date 2.5 Compilation of Findings and Conclusions For this assessment … The three remaining articles, were abstracted into an evidence table (Appendix B) for this assessment … Assessment of the Need to Update Comparative Effectiveness Reviews: Report of an Initial Rapid Program … Assessment (2005-2009) (Prepared by the Southern California Evidence-based Practice Center).

295. Suicidal-Thoughts-Young-People-Amendement-May-2025 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
     January 01, 2025 - We added an evaluation of scalability to the applicability assessment. KQ 1. … (e.g., long-term outcome assessment, short-term outcome assessment) • Social determinants of health … Assessment of the Risk of Bias of Individual Studies We will evaluate the risk of bias of the included … Based on this assessment and the initial study design, we will assign SOE rating as high, moderate, … Identification of Relevant Studies to Answer the Key Questions Data Abstraction and Data Management Assessment

296. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
     July 01, 2012 - Introduction “Grading” refers to the assessment of the strength of the body of evidence supporting … An assessment of the strength of the entire body of evidence includes an assessment of the quality of … Evidence Report/Technology Assessment No. 160. … Evidence Report/Technology Assessment No. 1. … Evidence Report/Technology Assessment No. 180.

297. Pharmacologic Management of Acute Pain by EMS in the Prehospital Setting Protocol Amendment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
     January 28, 2019 - optimizing opioid exposure creates a need for clinicians to have a thorough understanding of pain assessment … tools in the prehospital setting particularly in the absence of a gold standard assessment tool.8 Of … Contextual Question 2: What is the evidence regarding use of pain assessment tools in the prehospital … Assessment of Methodological Risk of Bias of Individual Studies - The assessment of risk of bias for … Assessment of pain in the transport environment: a review of the literature.

298. Critical Analysis of the Evidence for Patient Safety Practices in Nursing Home Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nursing-home-safety_research-protocol.pdf
     July 22, 2015 - The Quality Measures are derived from the Minimum Data Set (MDS) of regularly collected assessment information … An overview of the existing literature and an assessment of gaps in systematic reviews and primary research … Assessment of the fundamental domains of a systematic review did not raise any concerns with the review … High risk of bias One or more of the concerns raised during the assessment of the fundamental domains … http:www.effectivehealthcare.ahrq.gov http://www.cms.gov/Medicare/Quality-Initiatives-Patient-Assessment

299. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
     August 05, 2010 - However, study duration will be considered in the assessment of the quality and applicability of the … (CCOHTA), Bandolier, and the NHA Health Technology Assessment Programme. … Assessment of Methodological Quality of Individual Studies We will assess the methodological quality … These criteria are based on the Assessment of Multiple Systematic Reviews (AMSTAR) tool (systematic … Studies could receive one rating for assessment of efficacy and a different rating for assessment of

300. MEDLINE Searches (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
     March 01, 2009 - Retrospective assessment of hypercoagulability in breast cancer prevention trial. … Risk and risk assessment for breast cancer: molecular and clinical aspects. … Understanding mathematical models for breast cancer risk assessment and counseling. … Use of biomarkers for breast cancer risk assessment and prevention. … Available models for breast cancer risk assessment: how accurate are they?