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221. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
     January 01, 2010 - Trials often focus on benefits, with little effort to balance assessment of benefits with assessment … Trials often focus on benefits, with little effort to balance assessment of benefits with assessment … Assessment of harms is often a secondary consideration. … Often the assessment of harms within RCTs is a secondary consideration, the quality and quantity of harms … Comparative effectiveness reviews (CERs) should include both head-to-head and placebo-controlled RCTs for assessment

222. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
     January 01, 2010 - Trials often focus on benefits, with little effort to balance assessment of benefits with assessment … Trials often focus on benefits, with little effort to balance assessment of benefits with assessment … Assessment of harms is often a secondary consideration. … Often the assessment of harms within RCTs is a secondary consideration, the quality and quantity of harms … Comparative effectiveness reviews (CERs) should include both head-to-head and placebo-controlled RCTs for assessment

223. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
     June 01, 2012 - Determine the added value of the genetic test over existing risk assessment approaches. … Updated assessment of cystic fibrosis mutation frequencies in non-Hispanic Caucasians. … Evidence Report/Technology Assessment No. 146. … Evidence Report/Technology Assessment No. 146. … Evidence Report/Technology Assessment No. 172.

224. PowerPoint Presentation (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
     June 01, 2012 - Determine the added value of the genetic test over existing risk assessment approaches. … Updated assessment of cystic fibrosis mutation frequencies in non-Hispanic Caucasians. … Evidence Report/Technology Assessment No. 146. … Evidence Report/Technology Assessment No. 146. … Evidence Report/Technology Assessment No. 172.

225. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
     July 10, 2023 - Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of eligible studies by … Assessment of vaginal atrophy: a review. … PICOTS) All included studies were intended for risk of bias (ROB) assessment. … PICOTS) Allowed for any timing of outcome assessment. … Assessment of Methodological Risk of Bias of Individual Studies E. Data Synthesis F.

226. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (Amended) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
     July 02, 2020 - Quality Assessment For randomized controlled trials, quality will be assessed using criteria adapted … Clinical Evidence Assessment: Safety of Extended Use and Reuse of N95 Respirators. 2020. https://assets.ecri.org … Types of studies to be included: Literature Searches Data Extraction (Selection and Coding) Quality Assessment

227. App-F-Surv-Rept-1-Acute-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-rept-1-acute-pain.xlsx
     October 08, 2025 - Risk of bias assessment for randomized controlled trials Author, Year (Full Citations Are Listed in

228. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
     October 01, 2024 - We will not perform an independent assessment of original studies cited in any such systematic review … We will not endorse any specific toolkit. 8 Risk of Bias Assessment For studies that address … Pre-post studies have a high risk of bias by definition so we will not perform a detailed assessment … We will not perform an independent assessment of original studies cited in any such systematic review … Inclusion and Exclusion Criteria Literature Searches Description of Included Studies Risk of Bias Assessment

229. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
     January 01, 2012 - This observation tempered their overall assessment of the technology. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form.

230. Evidence-based Practice Center Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
     May 19, 2011 - Risk assessment; predictive models ii. … Assessment of Methodological Quality of Individual Studies For those KQs with applicable studies … For the assessment of systematic reviews, we will use the Assessment of Multiple Systematic Reviews … (AMSTAR) instrument to evaluate the quality of the review. 3 For the assessment of randomized and … This assessment will be based on the representativeness of United States-based studies (e.g., a national

231. Interventions to Improve Care of Bereaved Persons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
     June 01, 2023 - We will tailor the risk of bias assessment to the question the study is used to answers. … • Reporting bias: Reporting bias assessment will include an evaluation of whether a pre-specified … We will incorporate the risk of bias results into the strength of evidence assessment and downgrade … , Development and Evaluation), outlined in the AHRQ methods guide.45 The initial assessment will be … A scoping review of bereavement risk assessment measures: Implications for palliative care.

232. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
     September 19, 2014 - Risk Assessment and Risk Mitigation Strategies a. … Risk assessment and risk mitigation strategies a. … Risk assessment and risk mitigation strategies (continued) b. … QUADAS-2: A revised tool for the Quality Assessment of Diagnostic Accuracy Studies. … Evidence Report/Technology Assessment No. 218.

233. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
     January 30, 2020 - This review is limited to a 4 safety assessment. … Assessment of Methodological Risk of Bias of Individual Studies: All included studies will be assessed … The assessments will be undertaken by one reviewer; a second reviewer will check the assessment for … The strength of evidence assessment will use the AHRQ EPC program strength of evidence assessment categories … [Assessment of the MF59-adjuvanted pandemic influenza A/H1N1 vaccine.

234. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form. … (ECRI Institute, Technology Assessment). Horizon Scanning Structured Comment Form.

235. Making Healthcare Safer IV: Fatigue and Sleepiness of Clinicians Due to Hours of Service (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
     July 01, 2023 - quality systematic reviews defined using the criteria for “Good” described below in the Risk of Bias Assessment … We will not perform an independent assessment of original studies cited in any such systematic review … Risk of Bias (Quality) Assessment For studies that address Review Question 5 about the effectiveness … Assessment of Physician Sleep and Wellness, Burnout, and Clinically Significant Medical Errors. … quality systematic reviews defined using the criteria for “Good” described below in the Risk of Bias Assessment

236. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
     August 19, 2024 - For these reasons, timing of nutritional assessment during pregnancy matters and completion of multiple … nutritional assessments including assessment of dietary supplement use is needed to estimate usual … Assessment of Methodological Risk of Bias of Individual Studies In accordance with the AHRQ Methods … We will provide a qualitative summary of our assessment. V. References 1. … Regulating fatty acids in infant formula: critical assessment of U.S. policies and practices.

237. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
     July 01, 2023 - We will not perform an independent assessment of original studies cited in any such systematic review … We will not endorse any specific toolkit. 8 Risk of Bias (Quality) Assessment For studies … A statewide assessment of surgical site infection following colectomy: the role of oral antibiotics. … We will not perform an independent assessment of original studies cited in any such systematic review … Literature Searches for Studies of Effectiveness Description of Included Studies Risk of Bias (Quality) Assessment

238. Research White Paper_Machine Learning Tools To (Semi-)Automate Evidence Synthesis: A Rapid Review and Evidence Map, 2025 Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-white-paper-2025-update.pdf
     January 01, 2025 - Risk of bias assessment tools showed moderate agreement with human assessments (Cohen’s kappa = 0.20 … The reference standard for data extraction and risk of bias assessment is either the extracted data … 17101, 110-125 (11) Human assessment or assessment in the published review Cohen's weighted … A kappa score of 0.22 indicates slight to fair agreement. 3.2.8 Risk of Bias Assessment Tools … Language models for data extraction and risk of bias assessment in complementary medicine.

239. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - topics in the same class of a device, drug, or biologic are aggregated for discussion and impact assessment … reflects clinical practice, clinical research, health care delivery, health business, health technology assessment … This system, developed by Cerebral Assessment Systems, Inc. … Class II medical device and granted de novo clearance as a first-in-class computerized cognitive assessment … Cerebral Assessment Systems has begun developing commercial Cognivue units, with plans to distribute

240. Prostate-Cancer-Test Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
     October 14, 2011 - PCA3 will be excluded based on sample size but this element will be considered as part of quality assessment … Assessment of Methodological Quality of Individual Studies and Reviews To assess the methodological … Quality assessment will be performed by analyzing the individual items described above and their … Assessing Applicability In addition to quality assessment, we will also assess the applicability … Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies.