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effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - Consistent (i.e., no inconsistency)
Inconsistent
Unknown or not applicable (single study cannot be assessed … Defined as whether the evidence being assessed:
Reflects a single, direct link between the interventions … Frameworks” module
Four Required Domains: Directness
Directness concerns whether the evidence being assessed … The EPC approach emphasizes that applicability should be assessed separately from strength of evidence
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_surveillance.pdf
July 01, 2012 - assessments:
• If we found no new evidence or only confirmatory evidence and all responding experts
assessed … some new evidence that might change the CER conclusion, and /or a
minority of responding experts assessed … substantial new evidence that might change the CER conclusion, and/or a
majority of responding experts assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - Timing
Outcomes for Key Questions 1, 2, 4, 5, and 6 will be assessed at 1 year of follow-up and at … Studies labeled “ include” will be further assessed for
methodological quality as described in Section
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - The degree of harm from false-negative results can be assessed by considering the negative effects of … comparison have a high likelihood of adequate protection against bias (i.e., good internal validity), as assessed … This can be assessed through two main elements:
The range of study results is narrow. … Risk of bias is assessed mainly through reviewing the study design and the quality of the individual … Evidence Grading Examples: Considering Accuracy Outcomes (6 of 6)
Each domain should be assessed using
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - The degree of harm from false-negative results can be assessed by considering the negative effects of … comparison have a high likelihood of adequate protection against bias (i.e., good internal validity), as assessed … This can be assessed through two main elements:
The range of study results is narrow. … Risk of bias is assessed mainly through reviewing the study design and the quality of the individual … Evidence Grading Examples: Considering Accuracy Outcomes (6 of 6)
Each domain should be assessed using
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - conclusions of the included abstracts to the conclusions of the original CER and
surveillance reports, and assessed … If we found no new evidence or only confirmatory evidence and all responding experts assessed
the CER … found some new evidence that might change the CER conclusion, and /or a minority of
responding experts assessed … Full text articles for all citations progressed through the title/abstract review phase were assessed … We assessed the efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
April 01, 2014 - What studies have assessed whether specific clinical tools or implementation practices for
such quality … If no such studies of children are available, what studies have assessed whether specific
equivalent
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - TEP #2 Results –
KQ2
Botulinum toxin SOE is assessed as moderate (Table
11, page 62). … Similarly, were dropout
rates due to lack of efficacy assessed? … We assessed
dropout rates due to side effects as a measure
of harm, as was done in previous meta-
analyses
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - TEP #2 Results –
KQ2
Botulinum toxin SOE is assessed as moderate (Table
11, page 62). … Similarly, were dropout
rates due to lack of efficacy assessed? … We assessed
dropout rates due to side effects as a measure
of harm, as was done in previous meta-
analyses
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
March 22, 2016 - A number of reviews have assessed the evidence linking risk factors and
protective factors to Alzheimer … Additional data will be extracted from studies
assessed as having low to moderate risk of bias. … Assessment of Methodological Risk of Bias of Individual Studies
Risk of bias of eligible studies will be assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
February 01, 2010 - previously shown an effect of diabetes survival in patients randomized to
CABG and PCI.28 We also assessed … The composite endpoint of death or myocardial
infarction within 90 days, which could be assessed in … the proportional hazards assumption was not violated.
3
Several secondary endpoints could be assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
December 16, 2011 - For the remaining questions, the internal validity of RCTs and NRCTs will be assessed using
the Cochrane … Blinding and incomplete outcome data will be assessed separately for subjective
outcomes (e.g., depression … If one or more
individual domains are assessed as having a high risk of bias, the overall score will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - therefore preferences, have an important
vi
role in determining how benefits and harms are assessed … available methods
for use in systematic reviews.
13
The team looked for articles that quantitatively assessed … Investigator choices also affect decisions regarding the selection of outcomes to be assessed
in a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_surveillance.pdf
July 01, 2012 - study conditions and findings for each new included study into an
evidence table (Appendix B), we assessed … assessments:
• If we found no new evidence or only confirmatory evidence and all responding experts
assessed … found some new evidence that might change the CER conclusion, and /or a
minority of responding experts assessed … substantial new evidence that might change the CER conclusion, and/or a
majority of responding experts assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
June 01, 2010 - Detection bias is important in cohort studies in which outcomes in
comparison groups may be assessed … attrition bias) are not considered in this global assessment of
observational studies, but rather are assessed … Different study designs may be
optimal for different types of review questions, and study designs must be assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - Detection bias is important in cohort studies in which outcomes in
comparison groups may be assessed … attrition bias) are not considered in this global assessment of
observational studies, but rather are assessed … Different study designs may be
optimal for different types of review questions, and study designs must be assessed
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - For all studies, the overall study quality will be assessed as follows:
• Good (low risk of bias). … Grading the Evidence for Each Key Question
We will grade the strength of evidence for each outcome assessed … The strength of
evidence will be assessed by using the approach described in AHRQ’s Methods Guide.25,28
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - Pain was assessed heterogeneously across studies, which
did not permit conclusions about pain occurring
-
effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
July 08, 2015 - conclusions of the included
abstracts to the conclusions of the original CER and surveillance reports, assessed … If we found no new evidence or only confirmatory evidence and all responding experts assessed
the CER … found some new evidence that might change the CER conclusion, and /or a minority of
responding experts assessed … The nursing staff assessed pain on a numeric oral scale (range 0-10).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
March 16, 2017 - studies (KQ 4) or long-term followup
studies (KQ 7) found from existing systematic reviews will be assessed