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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - Scope and Key Questions
Scope of Review
The systematic review assessed the effectiveness
of systemic … We assessed the effectiveness of systemic
antibiotics, systemic corticosteroids and emerging
and other … Further,
we assessed the effectiveness of combinations of
treatments, and we compared different regimens … Lung function was the most frequently assessed
outcome, and often studies did not measure final
health … A
number of studies included patients assessed in
an emergency department with a broad range
of severity
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
December 01, 2024 - were inconsistent regarding the association between treatment
effect and baseline OCD severity as assessed … We assessed the risk of bias and evaluated the SoE using
standard methods. … were
inconsistent regarding the association between treatment effect and baseline OCD
severity as assessed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - Two reviewers independently assessed the full text of each
included study. … Strength of evidence is assessed
for a limited set of critical outcomes, typically those
related to … We assessed applicability by identifying potential
population, intervention, comparator, outcome, and … in the control group had crossed over to receive frenotomy
before outcomes were assessed.10
Harms … Overall, three good-
quality10,11,13 and one fair-quality12 RCT assessed whether
surgical treatment
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effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/topic-brief-updating-pharmacotherapy.pdf
September 30, 2022 - One RCT24 assessed variation in the effectiveness of Naltrexone
treatment by age. … Four RCTs22, 30-32 assessed
variation in the effectiveness of Naltrexone treatment using either daily … Four additional studies assessed the
effectiveness of Atomoxetine,37 Topiramate,38 and Nalmefene43 among … Appropriateness and Importance
We assessed the nomination for appropriateness and importance. … The impact of a new evidence review was qualitatively assessed by analyzing the current
standard of
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
January 01, 2011 - Credibility criteria of the index were assessed on a 7 point scale. … Major flaw
C Major confounding factors /effect
modifiers were assessed partially
Minor flaw … D Major confounding factors/effect
modifiers were assessed (known sets
of confounders specific for … Major flaw
Major confounding factors /effect
modifiers were assessed partially
Minor flaw … Major flaw Level A
Major confounding factors /effect
modifiers were assessed partially
Minor
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - In January 2014 AHRQ published a surveillance report that
assessed whether an update of CER No. 31 was … Only systematic reviews that assessed
and reported individual study risk of bias will be assessed for … Systematic review quality will be assessed using modified AMSTAR criteria.33 An
additional question … Were important
variables known to
impact the outcome(s)
assessed at baseline? … Yes Who assessed outcomes?
No
Uncertain Not reported
10.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - quality.15 Study-level risk of bias must be assessed using validated
risk of bias tools appropriate … Systematic review quality and risk of bias
will be assessed using modified AMSTAR criteria. … We will calculate MID for outcomes for
which strength of evidence is assessed. … Outcomes in studies assessed as
having a high risk of bias will be compared to synthesized evidence … The potential for reporting bias, when assessed, will be evaluated by the potential for
publication
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - All
information available on neonatal outcomes will be assessed. … Loss to followup will be assessed according to the process described below. … Unintended crossover to opposite intervention group(s) will be assessed based on
information reported … When not clearly reported in the paper, loss to followup will
be assessed by comparing the number of … Heterogeneity in outcomes will be assessed using Cochran’s Q, recognizing this
test has low power to
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
October 01, 2011 - The quality of each systematic review was assessed
using the Assessment of Multiple Systematic Reviews … The quality of each study was
assessed using criteria established by the USPSTF, and
poor quality studies … Data Synthesis
We assessed overall strength for each body of evidence
addressing a particular outcome … Two controlled trials assessed the efficacy of treatment
of subclinical hyperthyroidism; both of these … Both assessed changes in blood pressure.
One also evaluated change in BMI.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
August 01, 2012 - Protein turnover:
No studies
assessed the
association
between changes
in protein
turnover and … Exercise
tolerance: 10
observational
studies assessed
the association
between exercise
tolerance … Bone
mineralization:
No studies
assessed this
association. … Protein turnover:
No studies
assessed this
November 2011
No new studies
assessed these
associations … Exercise
tolerance: No
studies assessed
this association.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
December 01, 2011 - Two independent reviewers assessed
studies for inclusion in a parallel manner by using
criteria defined … Observational studies were not pooled
with RCTs and were assessed in a qualitative fashion
only. … Additional domains were not assessed because they
were deemed irrelevant to this review. … Only two direct comparative
randomized trials assessed for final health outcomes,51,52
and three direct … In patients with mixed ACS, the impact of device
therapy on many intermediate outcomes was not
assessed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
July 01, 2013 - The quality of individual RCTs was assessed using the
United States Preventive Services Task Force ( … The quality of harms reporting was assessed using the
USPSTF rating, with specific attention to both … Four
main domains were assessed: risk of bias, consistency,
directness, and precision. … Empty cells indicate outcomes that were not assessed. … The evidence
for benefit is truly insufficient; equivalence was not
assessed.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - conclusions:
• If we found no new evidence or only confirmatory evidence and all responding experts
assessed … No Signal
Adverse events:
Consistent to the original CER, the adverse events were not adequately assessed … Rate of Systolic BP slope
divergence:
Not assessed None One expert said the
conclusion was not … difference:
0.02 mg per deciliter; 95% CI=
−0.10, 0.06
“In a per-protocol analysis, there
Not assessed … ) – A2
• A superior new treatment (e.g., new treatment that is significantly superior to the one
assessed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
November 01, 2009 - Comparators assessed in the randomized controlled trials
Cancer type and center Comparison N Survival … Comparators assessed in the nonrandomized
comparative studies are shown in Table B. … Comparators assessed in the nonrandomized comparative studies
Cancer type and center Comparison N Survival
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
June 01, 2016 - However, few studies have assessed
potential long-term harms associated with beta-blocker
use in infants … *The overall evidence grade was assessed based on the ratings for the following domains: study limitations … ��Few studies have assessed the potential long-term
harms associated with using beta-blockers to treat … ��Most studies assessed in this review included children
with IH in multiple anatomic locations.
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effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - planned sensitivity analyses
Describe important subpopulations in which measures of effect will be assessed … planned sensitivity analyses, describe important subpopulations in which measures of effect will be assessed … Outcome
The association between exposure and outcome can also be assessed under different definitions … Describe important subpopulations in which measures of effect will be assessed for homogeneity. … planned sensitivity analyses, described important subpopulations in which measures of effect will be assessed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_executive.pdf
January 01, 2012 - Two reviewers independently
assessed quality, with differences resolved though
discussion, review of … We
assessed the strength of evidence for all surgical
interventions except LUNA and lysis of adhesions … With two RCTs, one of fair and one of
poor quality, we assessed the strength of evidence as
low for the … Cohort studies evaluated
outcomes of hormone-based therapy and assessed
nonsurgical compared with surgical … We assessed the strength of evidence for all nonsurgical
interventions as insufficient, with the exception
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - spectrum disorder; RCT = randomized controlled trial
Study Selection
Two reviewers independently assessed … Methods
Guide for Effectiveness and Comparative Effectiveness
Reviews.8 Two senior investigators assessed … Insufficient: Evidence is either unavailable or does not
permit a conclusion.9
Applicability
We assessed … Comparators
among nonplacebo controlled studies varied, and few
studies assessed the effect of concomitant … Few studies addressed the same agent and outcomes,
and few assessed potential factors that may modify
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - non-hormonal moisturizers, and
energy-based interventions for genitourinary syndrome of menopause (GSM)
were assessed … • Studies differed in GSM definitions and diagnosis, enrollment criteria, and
outcomes assessed for … yttrium aluminum garnet laser; HA=hyaluronic acid; MBS=most bothersome symptom; NR=not reported; N/A=not assessed … Explanations for downgrading:
aDowngraded one level for study limitations (one or more trials assessed
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
January 01, 2012 - Outcomes assessed (i.e., functional ability, utilization of chair, patient satisfaction,
quality of … McDonald54 and Telfer et al.55 assessed children’s
caregivers’ and parents’ opinions about the wheeled … Two
comparison groups
(one urban and one
rural) were assessed
face-to-face. … Parents and local
therapists matched
and assessed
regarding child. … Individuals assessed
for wheelchair during
4-month timeframe
once new assessment
practices were put