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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
    January 01, 2025 - All included studies were assessed as high risk of bias.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
    January 30, 2020 - We will apply the system to all assessed adverse events, thereby systematically identifying evidence … Events that were assessed in research studies but that did not occur will also be abstracted and entered … Assessment of Methodological Risk of Bias of Individual Studies: All included studies will be assessed … The synthesis will report how many studies have assessed an adverse event to answer KQ1a, KQ2a, and … For all influenza vaccines, asthma will be assessed.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
    December 01, 2015 - Risk-of-Bias Assessment We assessed risk of bias with three appropriate tools, described in more detail … Two reviewers assessed each domain independently and also assigned an overall grade for comparisons … Applicability We assessed the applicability both of individual studies and of the body of evidence … for risk of bias: 83 (105 articles) Systematic reviews assessed for quality: 1 Review team’s earlier … AHRQ systmeatic review on binge-eating disorder referenced for abstraction information and not assessed
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_surveillance.pdf
    May 16, 2013 - assessments: • If we found no new evidence or only confirmatory evidence and all responding experts assessed … The summary estimate was derived from meta-analysis of three RCTs that assessed the rhythm control … However, these studies assessed the results at nonuniform time points and therefore the findings may … Seventy-eight studies assessed the rates of asymptomatic or symptomatic PV stenosis. … However,  these  studies  assessed  the  results  at   nonuniform  time  points  
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - They assessed a subsequent set, establishing concordance among the team. … In adherence with the Methods Guide,29 the risk of bias of individual comparative studies was assessed … Preventive Services Task Force (USPSTF) criteria.31 The quality of the abstracted studies was assessed … The quality of the single-arm intervention studies was assessed by Carey and Boden criteria.32 These … The quality of individual studies was assessed as outlined in the preceding section, and the strength
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_executive.pdf
    May 01, 2013 - Two reviewers assessed each domain independently and assigned an overall grade for each treatment comparison … Applicability We assessed the applicability of individual studies as well as the body of evidence. … for eligibility n=764 Articles assessed for risk of bias n=96a Systematic reviews assessed for risk … Of the 17 articles not included in one of the five systematic reviews, we assessed 15 as medium risk … We assessed four systematic reviews as low risk of bias and one as medium risk of bias.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - Two reviewers assessed the included studies for sources of systematic bias according to the guidelines … Two reviewers assessed the methodological rigor of observational studies using a modified version of … Rating of Evidence We assessed the quantity, quality, and consistency of the body of available evidence … We assessed the quality and consistency of the best available evidence, including assessments of the … We retrieved the full text of 652 articles and assessed the studies for inclusion in this review.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - interventions relevant to U.S. practices. 6 Study Inclusion Decisions Two independent reviewers assessed … populations of mostly outpatients and duration of at least 12 weeks, and systematic reviews that assessed … Statistical heterogeneity was assessed using the I2 statistic or the Q-statistic chi-square. … Strength of the Body of Evidence The strength of evidence (SOE) for each prioritized outcome was assessed … Harms Outcomes Four trials and seven systematic reviews assessed or reported any type of harms associated
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/scarce-resources-protocol.pdf
    January 01, 2013 - was measured or could be inferred from the data provided, (4) generalizability of the findings was assessed
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nursing-staff-shortages.pdf
    October 01, 2024 - Healthcare Safer IV: Nursing Staff Shortages Review Questions Review Question What studies have assessed … the search to studies published in English, performed in the United States, and having each study assessed
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Timing: All time points; the last time point will be assessed if data on multiple time points are provided … Assessment of Methodological Quality of Individual Studies The internal validity of RCTs will be assessed … If one or more individual domains are assessed as having a high risk of bias, the overall score will … information on the source of funding will be collected for each study.22 Cohort studies will be assessed … source of funding will also be collected.22 The methodological quality of included studies will be assessed
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
    December 11, 2018 - Literature identified during the updated search will be assessed by following the same process of dual … characteristics of the population, interventions and the number of patients enrolled relative to the number assessed … Primarily RCTs will be assessed based on criteria and methods established in the Cochrane Handbook for … Key Question, condition of interest, and intervention, comparator, and outcome) will be initially assessed … Assessing Applicability Applicability will be assessed in accordance with the AHRQ's Methods Guide
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
    April 02, 2013 - Instead, we assessed critical domains for each study design (see methods). … For example, for RCTs we assessed randomization, allocation concealment, blinding, loss to followup … primary outcomes of the report---prevention of PTSD (including reduction of PTSD symptoms) --- was assessed … ES-12-13) We believe that harms need to be explicitly assessed to be able to draw reliable conclusions … Few studies, however, assessed such endpoints.”
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
    November 28, 2012 - Services Task Force.44 The quality of the abstracted studies and the body of evidence will be assessed … • The quality of studies will be assessed on the basis of the following criteria: o Initial … • The quality of included nonrandomized comparative intervention studies will also be assessed … • The quality of included single-arm intervention studies will be assessed based on a set of study characteristics … Assessing Applicability Applicability of findings in this review will be assessed within the EPICOT
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
    October 01, 2012 - Data Synthesis To determine whether quantitative analyses were appropriate, we assessed the clinical … Two reviewers assessed each domain for each key outcome; differences were resolved by consensus. … Applicability We assessed the applicability of the evidence following guidance from AHRQ’s Methods … references: 341 No. of articles screened (after removal of duplicates): 6,209 No. of full-text articles assessed … How can it be assessed? JAMA. 1988 Sept 23-30;260(12):1743-8. PMID: 3045356. 7. U.S.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
    May 02, 2025 - ROBINS-I comprises seven domains which will each be assessed: • Bias due to confounding • Bias in … The primary domains assessed include risk of bias, directness, consistency, precision, and reporting … How effects on health equity are assessed in systematic reviews of interventions. … Added text to clarify that in this situation, other domains will not be assessed.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
    October 08, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …
  18. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
    October 08, 2025 - Assessing Applicability: Interactive Case Study Quiz Assessing Applicability Interactive Quiz Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Assessing Applicability Interactive Quiz Why might trials with run-in periods and …
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - Assessment of Methodological Risk of Bias of Individual Studies: Risk of bias of eligible RCTs will be assessed … Risk of bias for non-RCTs will be assessed using the ROBINS-I tool.15 8 One investigator … collect results data from the evidence tables of the previous review when studies and outcomes were assessed
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
    July 01, 2016 - * The overall evidence grade was assessed based on the ratings for the following domains: study limitations … Endoscopy with duodenal biopsy The histology of a duodenal biopsy is assessed according to the Modified

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