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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - Each study will be assessed for the following individual criteria: comparable study groups at baseline … Additionally, RCTs will be assessed for randomization technique and allocation concealment. … The risk of bias will be assessed through the evaluation of both design and study limitations. … Consistency will be assessed in two main ways, first the effect http://www.effectivehealthcare.ahrq.gov … final health outcomes, adequate study duration with clinically relevant treatment modalities, assessed
  2. effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/protocol
    August 01, 2022 - HRQOL)     Timing Any (timing may depend on treatments provided and outcomes assessed … Literature identified during the updated search will be assessed using the same process of dual review … RCTs will be assessed based on criteria and methods established in the Cochrane Handbook for Systematic … Applicability to U.S. practice settings will be assessed based on the Evidence-based Practice Center … Assessing Applicability Applicability will be assessed in accordance with the AHRQ's Methods Guide,
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
    February 01, 2019 - Literature identified during the updated search will be assessed by following the same process of dual … Assessment of Methodological Risk of Bias of Individual Studies RCTs will be assessed based on criteria … Studies included in prior systematic reviews conducted by our EPC that are relevant to this review were assessed … for Major Comparisons and Outcomes The strength of evidence for each Key Question will be initially assessed … Assessing Applicability Applicability will be assessed in accordance with the AHRQ's Methods Guide,
  4. effectivehealthcare-admin.ahrq.gov/products/cystic-fibrosis-hgh/research-protocol
    December 01, 2019 - Pulmonary function is most commonly assessed by forced expiratory volume in one minute (FEV1), which … terminal endpoints in patients with CF are evaluated) and 5 (where the malignant effects of rhGH are assessed … Each study will be assessed for the following individual criteria: comparable study groups at baseline … Additionally, randomized controlled trials will be assessed for randomization technique and allocation … Observational studies will be assessed for sample size, participant selection method, exposure measurement
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
    January 01, 2023 - (RoB) assessment for each of the new studies identified in this update using RoB 2.16 RoB will be assessed … transparency and ease of future updating, the EPC will include detailed definitions related to how RoB was assessed … the Strength of Evidence (SOE) for Major Comparisons and Outcomes: Strength of evidence will not be assessed … 5.2) Is the numerical result being assessed likely to have been selected, on the basis of the results … 5.3) Is the numerical result being assessed likely to have been selected, on the basis of the results
  6. effectivehealthcare-admin.ahrq.gov/products/pressure-ulcer-prevention/research-protocol
    December 01, 2019 - A systematic review published in 2006 identified three studies from the 1990s that assessed the effect … A systematic review published in 2006 found that 51 of 59 included randomized controlled trials assessed … studies Systematic reviews will be used as primary sources of evidence if they address a KQ and are assessed … Literature identified during the updated search will be assessed by following the same process of dual … Grading the Evidence for Each Key Question The strength of evidence for each KQ will be assessed by
  7. effectivehealthcare-admin.ahrq.gov/products/depression-pregnancy-postpartum/research-protocol
    December 01, 2019 - environmental) that might impact maternal and child outcomes during treatment of perinatal depression will be assessed … Titles and abstracts will first be assessed by one reviewer, with a second reviewer assessing only those … Full-text articles of all potentially relevant titles and abstracts will be retrieved and will be assessed … validity (quality) of systematic reviews, randomized trials, and cohort and case control studies will be assessed … Assessing Applicability Applicability will be assessed by paying special attention to study eligibility
  8. effectivehealthcare-admin.ahrq.gov/products/osteoarthritis-pain/research-protocol
    December 01, 2019 - The purpose of this comparative effectiveness review (CER) is to update the previous report that assessed … clear statement of the questions(s), reported inclusion criteria, used an adequate search strategy, assessed … validity, performed dual data abstraction, reported adequate detail of included studies, assessed for … statistical analyses of potential confounders. 11 The applicability of trials and other studies will be assessed … An important limitation of observational studies of NSAIDs was that none simultaneously assessed the
  9. effectivehealthcare-admin.ahrq.gov/products/heart-disease-ace-inhibitor-arb/research
    December 01, 2019 - Partly out of date : This report was assessed in July 2015 and some conclusions may not be current.
  10. effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-risk-assessment-genes/research
    December 01, 2019 - The limited evidence on clinical validity is insufficient to conclude that the panels assessed would
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/joint-replacement-disposition-comments.pdf
    November 03, 2021 - used for grading the strength of evidence and how certain domains (e.g., directness, precision) were assessed
  12. effectivehealthcare-admin.ahrq.gov/products/juvenile-arthritis-dmards/research
    December 01, 2019 - Page Contents Archived : This report was assessed
  13. OUTLINE (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-end-of-life-measures-framework_research.pdf
    April 01, 2010 - For example, while pain on the individual patient level could be assessed with a visual analog scale … • Ready data sources: The extent to which the data required can be assessed or determined from available … for emotional and financial stress, and whether caregiving burden and assistance needs had been assessed … How can it be assessed? JAMA 1988;260(12):1743-1748. 5. Lorenz K, Lynn J, Dy SM, et al. … (Physical) Multiple Policy/procedure specifying frequency with which pain and dyspnea should be assessed
  14. OUTLINE (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-framework_research.pdf
    April 01, 2010 - For example, while pain on the individual patient level could be assessed with a visual analog scale … • Ready data sources: The extent to which the data required can be assessed or determined from available … for emotional and financial stress, and whether caregiving burden and assistance needs had been assessed … How can it be assessed? JAMA 1988;260(12):1743-1748. 5. Lorenz K, Lynn J, Dy SM, et al. … (Physical) Multiple Policy/procedure specifying frequency with which pain and dyspnea should be assessed
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-evidence-summary.pdf
    January 01, 2020 - Applicability We assessed applicability following guidance from the Methods Guide for Effectiveness … BFHI Interventions Twelve included studies (described in 13 publications) assessed the effectiveness … (Non-BFHI) Health Care System–Based Interventions Fifteen studies (described in 16 publications) assessed … Included studies assessed heterogeneous interventions and policies; key findings and SOE assessments … English),73 and one prospective cohort study assessed a tailored breastfeeding counseling intervention
  16. effectivehealthcare-admin.ahrq.gov/products/integrated-pain-management/protocol
    December 01, 2020 - Literature identified during the updated search will be assessed by following the same process of dual … the Risk of Bias of Individual Studies When Comparing Medical Interventions. 24 , 38 RCTs will be assessed … Publication bias will be assessed using funnel plots and statistical methods when there are at least … Grading the Strength of Evidence for Major Comparisons and Outcomes Outcomes to be assessed for strength … population, i.e. patients eligible for Medicare due to age ≥ 65 or disability (including ESRD), will be assessed
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/AI-tools-protocol.pdf
    August 15, 2023 - intersection of tool and task, so if a tool offers (semi-)automation for multiple tasks, it will be assessed … o Date tool assessed o Inputs (i.e., the instructions given to the AI, how model trained) o Outputs
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
    March 09, 2010 - • Outcome is change in one of the prespecified intermediate or final outcomes and is assessed by … • Outcome is change in one of the prespecified intermediate or long-term outcomes and is assessed … • Outcomes are determined a priori and are assessed by using an acceptable standard (KQ1-KQ4). … Grading the Evidence for Each Key Question The strength of evidence for each key question will be assessed … Questions KQ 1: KQ 2: KQ 3: KQ 4: KQ 5: The strength of evidence for each key question will be assessed
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
    August 22, 2008 - associated with increased morbidity and mortality in CF patients.7-10 Pulmonary function is most commonly assessed … terminal endpoints in patients with CF are evaluated) and 5 (where the malignant effects of rhGH are assessed … Each study will be assessed for the following individual criteria: comparable study groups at baseline … Additionally, randomized controlled trials will be assessed for randomization technique and allocation … Observational studies will be assessed for sample size, participant selection method, exposure measurement
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
    October 01, 2012 - We assessed the risk of bias and appropriateness of all studies that met our eligibility criteria, following … A low risk of bias was assessed if six or more of the items were scored as a “yes.” … A medium risk of bias was assessed if four or five of the items were scored as a “yes” or “unclear.” … A high risk of bias was assessed if zero to three items were scored as a “yes.” … Grading We assessed the strength of the best available evidence, including the risk of bias in relevant

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