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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
    April 01, 2021 - correspondence with six local experts with expertise in pain management and opioid tapering, in order to assess
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
    April 01, 2021 - correspondence with six local experts with expertise in pain management and opioid tapering, in order to assess
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
    April 25, 2013 - Composite endpoints are problematic to assess if individual endpoints making up the composite are not … Public Reviewer - ACCP 8 Results KQ1: The approach has been to look at studies which have assess … ACCP 8 Results KQ2: Non invasive assessments echo parameters and or biomarkers were looked at to assess … that the findings do not support any recommendations for replacing existing measurement tools to assess … Although there is still insufficient data to assess effects on mortality, and minimal data to assess
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - using a modified Cochrane risk-of-bias tool.42 We used additional items based on Sun et al.43 to assess … We developed an instrument to assess risk of bias for observational studies using the RTI item bank … articles (391 RCTs, 24 pooled analyses of patient-level RCT data, and 101 observational studies) to assess … Five different measures were used to assess pain in the MDD subgroup; the Brief Pain Inventory (BPI … Int J Technol Assess Health Care. 2012 Apr;28(2):138-44. PMID: 22559755. 82.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
    February 01, 2014 - Study Selection We developed screening forms to assess eligibility for inclusion in the review (Appendix … could affect applicability are the patient population (e.g. whether or not results are available to assess … Current studies are short term and have no ability to assess effectiveness over time, including long-term … Larger sample sizes are needed to assess comprehensively infant and longer term child outcomes as well
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
    December 15, 2010 - health status, comorbidities, baseline nutrient exposures and/or background diet), methods used to assess … In addition to quantitative data for each outcome, definitions, methods used to assess outcomes, and … eDefinition and methods used to assess outcome including timing, and comparability of assessment across … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews … The study may be missing information, making it difficult to assess limitations and potential problems
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - Additionally, the use of imaging to assess thromboembolic risk has not been formally reviewed to date … Data needed to assess quality and applicability, as described in the Methods Guide,25 will also be abstracted … Assessment of Methodological Quality of Individual Studies We will assess methodological quality, … The study may have been missing information, making it difficult to assess limitations and potential … Assessing Applicability We will assess applicability across our key questions using the method described
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-204-obesity-disposition-comments.pdf
    December 01, 2017 - This is an interesting issue, but it was beyond our scope of work to critically assess the spin in … We did not assess whether the studies were pre-registered in clinicaltrials.gov or another registration … As indicated above, we did not assess whether studies were registered, and would not expect to find … We were not able to assess whether “all confounders” were taken into account, and apologize if this … Absent an agreed upon list of relevant confounders, the best risk of bias assessment isto assess what
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
    December 17, 2013 - December 17, 2013 8 of sufficient length to be included in this review, we do not expect to be able to assess … The observational literature likely to be included rarely has protocols available to assess reporting … We will assess risk of bias for randomized controlled trials, if found in the literature, using an instrument … We will develop items for both risk-of-bias instruments to assess selective outcome and selective analysis
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
    August 01, 2013 - To assess applicability, we abstracted data from each included study on factors that could affect its … More research is needed to better assess the efficacy of these treatments. … More research is needed to better assess the impact of provider type on treatment outcomes.
  11. effectivehealthcare.ahrq.gov/sites/default/files/ch_6-user-guide-to-ocer_130129.pdf
    October 30, 2012 - While a physician may be able to assess improvement within an individual patient, a quantifiable measure … Or they may use the SLICC/ACR damage index, an instrument designed to assess accumulated damage since … Some specific measurement instruments assess multiple domains that are affected by a condition. … This approach will allow comparisons with the new measure to assess content validity if there is some … For example, if questions in a PRO to assess ability to perform physical activities are too “easy”
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
    January 01, 2006 - • Too few events have been reported in RCTs to accurately assess CV risk associated with lumiracoxib … • There is insufficient evidence to assess the balance of GI and CV safety of higher dose aspirin … Large, long-term trials with active and placebo- controlled arms would be needed to assess the safety … • Meta-analyses of the risks associated with selective COX-2 inhibitors need to continue to assess … Cohort studies using large observational databases may be required to adequately assess CV risk.
  13. Autism Surveillance (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_surveillance.pdf
    October 01, 2012 - Strength of evidence is insufficient to assess effects of social skills training on core autism outcomes … No other allied health interventions had adequate research to assess the strength of evidence. … Strength of evidence is insufficient to assess effects of social skills training on core autism outcomes … No other allied health interventions had adequate research to assess the strength of evidence.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
    December 06, 2010 - Assessment of Methodological Quality of Individual Studies To assess the quality (internal validity) … To assess the quality of observational studies, we will use criteria outlined by Deeks and colleagues … Health Technol Assess 2003;7(27):1-173, iii-x. 6.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
    August 01, 2012 - purpose of this mini-report is to apply the methodologies developed by the Ottawa and RAND EPCs to assess … followed a priori formulated protocol to search and screen literature, extract relevant data, and assess … For any CER that contains meta-analysis (es) we first assess for, the qualitative signal(s), and if … no qualitative signal(s) are found, we then assess for quantitative signal(s). … insufficient detail about methods used in the yet- to-be published randomized trial, so it is difficult to assess
  16. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Incomplete description of protocols, populations, and outcomes can make it impossible to assess clinical … However, whichever method the investigators choose, they should assess the invariance of treatment … Use of permutation test for meta- regression can help assess the level of statistical significance of … Health Technol Assess 2005;9:1–148. 18. Song F, Glenny AM, Altman DG. … Int J Technol Assess Health Care 1993;9:440–449. 59. Prevost TC, Abrams KR, Jones DR.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Incomplete description of protocols, populations, and outcomes can make it impossible to assess clinical … However, whichever method the investigators choose, they should assess the invariance of treatment … Use of permutation test for meta- regression can help assess the level of statistical significance of … Health Technol Assess 2005;9:1–148. 18. Song F, Glenny AM, Altman DG. … Int J Technol Assess Health Care 1993;9:440–449. 59. Prevost TC, Abrams KR, Jones DR.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults-future_research.pdf
    July 01, 2013 - What should be included in a taxonomy for assisted living to assess the effectiveness of services and … Prospective cohort studies enroll and follow patients over time to assess outcomes. … What should be included in a taxonomy for assisted living to assess the effectiveness of services and … What should be included in a taxonomy for assisted living to assess the effectiveness of services and … What should be included in a taxonomy for assisted living to assess the effectiveness of services and
  19. effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_slutsky_comparing_medical_interventions.pdf
    November 01, 2008 - The Evidence-based Practice Centers undertake a broad variety of reviews that assess the effectiveness … As the research methodologies develop, the EHC Program will continue to assess the need to update the
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-interventions-comparing_methods.pdf
    November 01, 2008 - The Evidence-based Practice Centers undertake a broad variety of reviews that assess the effectiveness … As the research methodologies develop, the EHC Program will continue to assess the need to update the

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