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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
    February 01, 2013 - ...................................................................... 12 Using Gray Literature To Assess … Criteria to Avoid Bias in Selecting Studies, Study Selection Process, and Using Gray Literature to Assess … Dual review—having two reviewers independently assess citations for inclusion—is one method of reducing … Using Gray Literature To Assess and Reduce Bias In reviewing gray literature documents, reviewers are … Health Technol Assess. 2003;7(41):1-106. PMID: 14670218. 31.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
    December 20, 2011 - Subgroup analyses for age, gender and co-morbidities will be undertaken to assess clinical diversity … Grading the Evidence for Each Key Question We will assess the overall strength of the evidence (SOE … For KQ1 and KQ2, we will assess SOE using the method for medical tests 29 and for KQ6 we will use … We will assess applicability in accordance with the Methods Guide for Medical Test Reviews. 29 … Evid Rep Technol Assess 2006;(142):1-147. 5. de Lemos JA, McGuire DK, Khera A, et al.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
    July 01, 2023 - When assessing non-randomized studies, we will use specific items in the ROBINS-I tool that assess … Evid Rep Technol Assess (Summ). 2001(43):i-x, 1-668. PMID: 11510252. 11. … Evid Rep Technol Assess (Full Rep). 2013 Mar(211):1-945. PMID: 24423049. 12.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
    January 01, 2010 - In addition, they would like to assess whether use of these quality measures or performance metrics,
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
    June 11, 2014 - We will, however, re-assess non-English studies as we update our MEDLINE search. … deem to be of low risk of bias and able to affect conclusions • For KQ 5, studies must explicitly assess … Assessment of Methodological Risk of Bias of Individual Studies We will assess the quality of studies … We will use the McMaster Quality Assessment Scale of Harms (McHarm) tool to assess harms studies.52 … Two senior investigators will independently assess each included study.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-child-interventions_research-protocol.pdf
    March 26, 2012 - To assess the risk of bias of studies, we will use criteria described in the AHRQ Methods Guide for … will use questions specified in the RTI Item Bank36 and the Cochrane Risk of Bias tool.37 We will assess … To determine whether quantitative analyses are appropriate, we will assess the clinical heterogeneity … Two reviewers will assess each domain for each key outcome listed in the framework, and conflicts will … To assess the applicability of a body of evidence, we will consider the consistency of results across
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
    September 02, 2016 - For newly found studies, we will record additional data and assess their risk of bias. … For studies identified in the original review, we will also assess the congruence of any additional … If meta-analyses are not conducted, we will assess whether the new studies fall within the range of … Evid Rep Technol Assess (Summ). 2004 Mar(94):1-8. PMID: 15133888. 18. … Evid Rep Technol Assess (Summ). 2004 Mar(93):1-6. PMID: 15133887. 19.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - We will not independently assess original studies included in any such systematic review. … When assessing non-randomized studies, we will use specific items in the ROBINS-I tool that assess … We will not independently assess original studies included in any such systematic review.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
    June 05, 2024 - evolve and it will not be practical to evaluate each new generation of a test in a large trial to assess … Objectives of the Review This systematic review will assess the accuracy, effectiveness, and harms … In some cases, we may report an outcome-specific ROB rating within a study if we assess the outcome … Two reviewers will independently assess the ROB for each study; disagreements on domain-level ratings … For KQs 1 and 2, we will assess reporting bias by comparing protocols to final reported methods and
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
    January 28, 2019 - Impetus for the Review This systematic review will assess the comparative effectiveness and harms … may contact authors of candidate articles for clarification of reported study details in order to assess … non-randomized studies, we will use the Newcastle Ottawa Scale.18 Two reviewers will independently assess … When quantitative pooling of studies is possible, we will assess for the presence of statistical heterogeneity … To assess for the presence of publication bias, visual inspection of funnel plots will be considered
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
    September 18, 2012 - can monitor the safety of clinical trial subjects and ensure that the study design is appropriate to assess … Assessing Strength of Evidence: Grading the Strength of Evidence for Individual Outcomes We will assess … applicability in mind; furthermore, they sometimes report only a few of the factors needed to fully assess … Evidence tables will clearly distinguish studies designed to assess effectiveness versus those designed … specifically to assess safety.
  12. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
    February 17, 2016 - February 17, 2016 9 Assessment of Methodological Risk of Bias of Individual Studies – We will assess … body of evidence as per the AHRQ methods guide on assessing the strength of evidence.5 We plan to assess … AHRQ approach, for each intervention and comparison of intervention, and for each outcome, we will assess … Assessing Applicability: We will assess the applicability within and across studies with reference to … At a minimum, factors of interest to assess applicability will be the key potential modifiers listed
  13. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
    November 01, 2021 - In question 1d, we will assess whether the literature suggests whether these adverse effects differ … • Study-specific sources of bias: In addition to the types of bias listed above, we will assess … We will use this information to assess the situations in which the evidence is most relevant and to … Evid Rep Technol Assess (Summ). 1999 Nov(11):i-viii, 1- 341. PMID: 10790990. 77. … Evid Rep Technol Assess (Full Rep). 2011 Apr(200):1-645. PMID: 23126627. 91.
  14. Prognostic Tests (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv.
  15. Prognostic Tests (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv. … Health Technol Assess 2006 Apr;10(14):1-144, iii-iv.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
    June 21, 2021 - non-English language articles to identify studies that would otherwise meet inclusion criteria, in order to assess … Risk of Bias of Individual Studies: Predefined criteria will be used to assess the risk of bias (also … The study may be missing information, making it difficult to assess limitations and potential problems … To address this, we will assess the fit of the GRADE-CERQual approach to our included studies for these … questions.49 If applicable to the body of literature, we will assess SOE based on the following domains
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
    December 11, 2018 - the Department of Health & Human Services (HHS) to contract with the Institute of Medicine (IOM) to assess … We will assess strength of evidence and draw conclusions based on the totality of evidence available … of Bias of Individual Studies The predefined criteria used for the 2018 report will be used to assess … The study may be missing information, making it difficult to assess limitations and potential problems … We will use this information to assess the situations in which the evidence is most relevant and to
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - for inclusion based on the Key Questions and PICOTS, the following data were abstracted and used to assess … No trial was designed to assess serious GI or CV harms associated with intermittent dosing strategies … Large, long-term trials with active and placebo- controlled arms would be needed to assess the safety … • Meta-analyses of the risks associated with selective COX-2 inhibitors need to better assess for the … Additional head-to-head trials and large cohort studies may be required to adequately assess serious
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - Since 2005, there have been significant advances in the devices used to assess optic nerve structure … several published studies on new diagnostic tests, such as frequency doubling technology, used to assess … The advantage of stereo photographs is that they enhance the reviewer’s ability to assess optic nerve … The images collected by SLP can be analyzed to assess the thickness of the RNFL, which is directly … Health Technol Assess. 2007;11(41). 17 8.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
    January 01, 2010 - This allows patients to evaluate their individual response to therapy and assess whether blood sugar … A systematic review of the literature is required to assess the quality and completeness of the current … The study may have been missing information, making it difficult to assess limitations and potential … We will assess the risk of bias of individual studies according to study design characteristics, such … We will assess the strength of the best available evidence by assessing the limitations to individual

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