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261. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
     January 01, 2013 - comparator treatment) Can differ in each group, especially if different treatment modalities are used Assess … time window Period where therapeutic benefit and/or risk would plausibly occur Sensitivity analysis to assess … regarding the appropriate duration of the exposure window(s), sensitivity analyses should be performed to assess … comparisons, understanding the recommendations from guidelines and standards of practice is necessary to assess … researchers need to recognize that misclassification is likely not comparable in both groups and need to assess

262. Amended Protocol: Maternal and Childhood Outcomes Associated with the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/wic-outcomes-nutrition-protocol-amended.pdf
     October 01, 2020 - Studies have used non-experimental designs and “natural experiment approaches” to assess effects, e.g … needed Type of study Qualitative or mixed-methods studies (e.g., interviews, focus group) that assess … We will not assess bias per se in individual qualitative studies. … However, two reviewers will assess the quality of studies using qualitative or mixed methods approaches … Following this standard EPC approach, for each key outcome, we will assess the number of studies, their

263. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
     January 30, 2020 - Evidence review scope: The scope of this systematic review of the evidence is to assess the safety of … the Assistant Secretary of Health/Office of Infectious Disease & HIV/AIDS Policy (OASH/OIDP) is to assess … Finally, for varicella and zoster vaccines, we will assess the presence and absence of adverse events … specifically to assess safety. … Evid Rep Technol Assess (Full Rep). 2014 Jul(215):1- 740. doi: 10.23970/AHRQEPCERTA215.

264. Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
     December 18, 2019 - There is a need to assess the benefits of outpatient vs. inpatient CR, without increasing risk (rise … applicability to other patients or settings. 3 Purpose of the Review This systematic review will assess … The study may be missing information, making it difficult to assess limitations and potential problems … The Key Questions are designed to assess the comparative effectiveness and harms by patient demographics … We will use this information to assess the situations in which the evidence is most relevant and to

265. Development of a Primary Care Guie for Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol Use With Epic-Based Electronic Health Record Tools: A Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - Additionally, to assess lessons learned, challenges, and barriers, we conducted semi-structured interviews … and screening-related assessment (and based on documentation in the electronic health record) To assess … workflow, to help us identify inflection points corresponding to introduction of new processes, to assess … We have continued to collect data since the end of the project period in order to assess maintenance … that don’t require EHR build team involvement) Use Validated Screening Instruments • None Assess

266. Evidence Summary: CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-231-dementia-interventions-evidence-summary_0.pdf
     August 01, 2020 - by 2060.1,2 The goal is to understand the evidence base for effective care interventions, and to assess … understand the evidence base for effective care interventions for PLWD and their caregivers in order to assess

267. Management of Suicidal Thoughts and Behaviors in Youth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
     February 05, 2025 - Purpose of the Review This systematic review will assess the effectiveness, comparative effectiveness … If evidence is available, we will also assess how differences in effectiveness and harms are influenced … the risk of bias of the included RCTs using the Cochrane Collaboration’s Risk of Bias 2 tool28 to assess … will follow the procedures outlined in the EPC Methods Guide for Comparative Effectiveness Reviews to assess … We will assess scalability of interventions by summarizing dropout rates and any other relevant information

268. Methods-Guide-Chapter-Prioritization-And-Selection-Of-Harms-For-Inclusion-In-Systematic-Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
     February 01, 2018 - However, although the 2010 harms chapter recommended that EPC systematic reviews “always assess harms … Other issues include whether to assess composite harms (e.g., “serious harms” or “withdrawal due to … the prior EPC methods work.8 The harms chapter of the EPC Methods Guide recommended that reviewers assess … Challenges in systematic reviews that assess treatment harms. … • Do not assume studies adequately assess harms because methods used to assess and report benefits

269. Glasgow.Presentation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_glasgow_presentation.pdf
     January 01, 2009 -  Approach  to  Patient-­‐Centered  Care   5’s  activity/  Multimedia  Example   • Assess … Model:    A  Guide  for  Making  Decisions   about  Self-­‐management  Plans   • ASSESS

270. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
     May 24, 2010 - and scientific directors, contact reviewers to determine progress and collect completed reviews, and assess … For observational study quality, we will use the AHRQ tools to assess quality of observational studies … The study may be missing information, making it difficult to assess limitations and potential problems … Meta-analysis to assess risk factors for recurrent Clostridium difficile infection. … Meta-analysis to assess risk factors for recurrent Clostridium difficile infection.

271. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - evaluated the quality of individual studies using the approach described in the Methods Guide.20 To assess … the severity of PAH, to predict events such as lung transplantation or death, or to assess a patient … Our findings do not support any recommendations for replacing existing measurement tools to assess … We reviewed 37 studies involving 4,192 patients that assess the effectiveness of drug treatment for … There was also concern that the population was not always adequately described to assess applicability

272. Research Protocol: Improving Cultural Competence To Reduce Health Disparities for Priority Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
     July 09, 2014 - Only systematic reviews that assess included study risk of bias will be assessed for review quality. … Additional items will be developed to assess potential risk-of-bias not addressed by the Cochrane tool … Two investigators will independently assess risk of bias for all included studies. … We will assess strength of evidence for outcomes drawn from more than one study for a given patient … Are the statistical methods used to assess the primary outcomes appropriate to the data?

273. Glasgow Coma Scale for Field Triage of Trauma: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow_executive.pdf
     January 01, 2017 - trauma systems, as it helps to identify potentially seriously injured patients Purpose of Review To assess … developed for evaluation of studies on prognosis27 and diagnosis.28 Investigators did not review, assess … – Evidence was insufficient to assess effects of patient or assessor characteristics on comparative … For predictive utility, prospective studies that independently assess patients using the tGCS and the … Finally, studies that assess measures of predictive utility other than discrimination (e.g., calibration

274. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
     April 01, 2013 - Additional results will be scanned, and medical librarians will assess their relevancy. … We will assess the risk of bias by following the guidelines in the chapter, “Assessing the Risk of Bias … For KQ 3, we plan to use the same rating system as described in the 2008 report to assess risk of bias … We will use I-squared29 and tau30 tests to assess heterogeneity in study results. … We will assess strength of evidence by following the guidelines from the chapter, “Grading the Strength

275. Grading_didactic_faculty_approved (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
     January 01, 2010 - Objectives Is distinct from rating the quality of individual studies Is generally used only to assess … The grading step requires reviewers to assess the aggregate quality of studies within each major study … In the absence of statistical testing or measurement of heterogeneity, EPC reviewers can assess consistency … In addition, EPC reviewers should assess the resulting interrater reliability for each domain. … present information that will help decisionmakers judge the risk of bias in the estimates of effect, assess

276. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-cough_research-protocol.pdf
     October 22, 2012 - underlying cause of the cough should not make the instrument perform differently in its ability to assess … endotracheal intubation) Interventions • KQ 1: Qualitative and quantitative instruments used to assess … Assessment of Methodological Quality of Individual Studies We will assess the methodological quality … The study may have been missing information, making it difficult to assess limitations and potential … Assessing Applicability We will assess applicability across our key questions using the method described

277. Asthma-Immunotherapy-2011 Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
     January 01, 2011 - Credibility of the Checklists To Assess Quality of Observational Studies (Evaluation by Participating … Int J Technol Assess Health Care 1995 Fall;11(4):770-778. 38. … How did the authors find the studies and assess their quality? … Health Technol Assess 2000;4(2):i-iv, 1-111. 58. Ariens GA, van Mechelen W, Bongers PM, et al. … Stat Methods Inter- Rater Reliability Assess 2002;3:1-16. 115. Gwet KL.

278. Emergency Medical Service/911 Workforce Infection Control and Prevention Issues (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
     January 01, 2015 - Two members from the team will independently assess each citation to determine whether it meets inclusion … To assess effectiveness, we will abstract data on the main outcomes of each study, whether or not there … Paired reviewers will independently assess the quality of each study by focusing primarily on classifying

279. Assessment of the Need to Update Comparative Effectiveness Reviews: Report of an Initial Rapid Program Assessment (2005-2009) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rapid-assessment-research-updates/research

280. March 2nd Mitigating Racial Bias in Healthcare Algorithms Public Meeting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
     May 15, 2023 - introduced at all stages of algorithm development and implementation o Organizations making efforts to assess … both KQs • Assessed studies’ methodologic ROB using ROBINS-I and piloted an appraisal supplement to assess … Assess whether performance of a tool at approval/clearance holds up in use with RWD, and if any biases … from a health equity lens and that methods are adequately reported • Invest in further research to assess … algorithms 107 Potential Next Steps (2) • Cross-specialty learning to develop best approaches to assess