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221. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
     January 01, 2013 - hypothesized direction of effect within subgroups and the significance levels that will be used to assess … adherence to sound study design principles by evaluating balance on covariates within subgroups to assess … hypothesized direction of effect within subgroups and the significance levels that will be used to assess … methods to adjust for multiple testing, if applicable Describe how confounding will be addressed - Assess

222. Medication-Therapy-Management Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
     January 01, 2014 - Specific concerns for our review include including questions to assess selection bias, confounding, … If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus … Assessing Applicability We will assess applicability of the evidence following guidance from the … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews

223. Colorectal-Cancer-Protocol_130520 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
     May 20, 2013 - combination of tests) for correctly establishing the stage of the cancer, it is also important to assess … We will assess the risk of bias of each individual study (see the section on assessing the risk of bias … of individual studies) to assess its risk of bias for each outcome and will use the aggregate risk … Int J Technol Assess Health Care. 2006 Summer;22(3):288-94. PMID: 16984055 16. … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews

224. Cerebral-Palsy-Feeding Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cerebral-palsy-feeding_executive.pdf
     March 01, 2013 - We used the included systematic review on behavioral interventions16 to assess strength of evidence … A study may be missing information, making it difficult to assess limitations and potential problems … No studies were designed or powered to directly assess modifiers of the effectiveness of behavioral … Health Technol Assess 2003;7(27):iii-x, 1-173. PMID: 14499048. 35. … External validation of a measurement tool to assess systematic reviews (AMSTAR).

225. Effects of Dietary Sodium and Potassium Intake on Chronic Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
     April 18, 2017 - studies of sodium reduction and potassium and the suitability and robustness of the RCT design to assess … chloride [salt] or sodium-to-potassium ratio) with validated measures or use biomarker values to assess … Assessment of Methodological Risk of Bias of Individual Studies We will assess the methodological risk … One reviewer will assess the methodological risk of bias for all included studies and at least one other … Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will assess the strength

226. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
     August 18, 2011 - Moreover, the previous review did not assess the impact of system-level interventions on adherence. … 4 Thus, in our review, we would like to assess these interventions and those at the patient and provider … To assess the quality (internal validity) of studies, we will use predefined criteria based on those … To determine whether quantitative analyses are appropriate, we will assess the heterogeneity of the … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus

227. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
     October 05, 2015 - We understand that a practical need exists to assess the accuracy of available risk assessment tools … We will review systematic reviews (SRs) that address any parts of our KQs and dually assess them for … If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical heterogeneity … We will follow EPC guidance to assess publication bias.62 Depending on the evidence available to us, … Two trained reviewers will assess each domain for each key outcome; differences will be resolved by

228. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - Int J Technol Assess Health Care 2001;17(3):433-441. 6. … Evid Rep Technol Assess (Full Rep) 2008;(172):1-362. 7. … Evid Rep Technol Assess (Full Rep) 2008;(167):1-195. 8. … Evid Rep Technol Assess (Full Rep) 2007;(160):1-105. 9. … Assess the impact of developing Research Needs documents.

229. Can Physical Activity Improve the Health of Wheelchair Users? Amended Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
     June 21, 2019 - and wheelchair mobility programs points out a clear need for more programs, particularly those that assess … National Center for Medical Rehabilitation Research for a Pathways to Prevention (P2P) workshop to assess … The study may be missing information, making it difficult to assess limitations and potential problems … The I-squared statistic will be used to assess statistical heterogeneity. … We will use this information to assess the situations in which the evidence is most relevant and to

230. Living Systematic Review on Plant-Based Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
     March 29, 2023 - Purpose of the Review This is a “living systematic review” (LSR), which will assess the effectiveness … Eligible observational studies must assess a mean duration of treatment of one month, and have concurrent … language articles to identify studies that would otherwise meet inclusion criteria in order to help assess … Grading the Strength of Evidence for Major Comparisons and Outcomes We will assess the strength of … We will use this information to assess the situations in which the evidence is most relevant and to

231. Research Protocol: Measuring Healthcare Organization Characteristics in Cancer Care Delivery Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-care-delivery-research-protocol.pdf
     October 06, 2022 - efforts have sought to expand our understanding of the quality of care, measurement frameworks to assess … In addition, many measures used to assess organizational characteristics were investigator- developed … Some of these characteristics are straightforward to assess. … al. review, which found that investigators frequently had to rely on study-specific survey items to assess … Paired reviewers will independently assess the quality of information about the organizational characteristic

232. Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
     January 01, 2024 - Clinician-Administered PTSD Scale (CAPS) and the PTSD CheckList (PCL) were measures most frequently used to assess … The CAPS and the PCL were measures most frequently used to assess continuous PTSD outcomes, used in

233. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
     December 09, 2009 - Assessment of Methodological Quality of Individual Studies To assess the quality (internal validity) … To assess the quality of observational studies, we will use criteria outlined by Deeks and colleagues … : December 9, 2009 9 For each of these comparisons, we will first stratify by whether the data assess … Health Technol Assess 2003;7: iii-x, 1-173. 4.

234. Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
     January 01, 2015 - Assess the impact of noncyclic chronic pelvic pain on the use of health services. 10. … Determine optimal followup to assess outcomes following surgical interventions. 15. … Systematically assess the role in CPP treatment for: i. Physiotherapy ii. … · Long term followup of surgery treatment is needed to assess outcomes. … Assess the impact of noncyclic chronic pelvic pain on the use of health services. CER 54.

235. Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
     November 02, 2019 - Information from grey literature will also be used to assess publication and reporting bias and inform … non-RCTs will be assessed using the ROBINS-I tool.15 8 One investigator will independently assess … We will assess the clinical and methodological heterogeneity and variation in effect size to determine … will use the Grading of Recommendations Assessment, Development and Evaluation (GRADE)19 approach to assess … differ from those of the population of treatment naïve men with CLPC affect applicability.21 We will assess

236. Medical Care for Adults with Down Syndrome (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
     July 09, 2024 - for Alzheimer-type dementia at age 40.22 Purpose of the Review This systematic review will assess … Where possible, gray literature will also be used to assess and inform future research needs. … If meta-analysis is possible, we will assess the clinical and methodological heterogeneity and variation … Strength of Evidence (SOE) for Major Comparisons and Outcomes Two investigators will independently assess … Abbreviations: AHRQ Agency for Healthcare Research and Quality AMSTAR A Measurement Tool to Assess

237. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
     July 01, 2012 - Medical tests may also be used to assess immediate or future response to treatment, including the probability … physical examination, as well as scored questionnaires intended, for example, for screening or to assess … Medical Test Methods Guide complements AHRQ’s General Methods Guide,1 which focuses on methods to assess … describe how to determine the key questions, as well as in chapters 5 and 6, which describe how to assess … Here we suggest that systematic reviewers search the literature to assess which factors are likely to

238. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
     January 09, 2020 - the risk of bias of the included RCTs using the Cochrane Collaboration’s Risk of Bias 2 tool22 to assess … will follow the procedures outlined in the EPC Methods Guide for Comparative Effectiveness Reviews to assess … systematic reviews evaluating triptans or NSAIDs, we will use the AMSTAR tool (A measurement tool to assess … systematic reviews) to assess the credibility of these systematic reviews. … tool evaluates 11 items: a priori protocol, duplication of reviewers, grey We added methods to assess

239. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0161_09-01-2009.pdf
     January 01, 2009 - Several randomized controlled trials are available that assess the effectiveness of Buteyko and other

240. Opioid Treatments for Chronic Pain Research Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
     December 19, 2018 - instrument on factors such as the methods used to conduct searches, select studies, abstract data, assess … The study may be missing information, making it difficult to assess limitations and potential problems … The key questions are designed to assess the comparative effectiveness and harms by patient demographics … We will use this information to assess the situations in which the evidence is most relevant and to … (risk and (predict$ or assess$)).ti,ab,kf. 27. or/17-26 28. 16 and 27 29. limit 28 to yr="2014