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101. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
     November 08, 2011 - facilities, and from 0 to 17 percent in the home-care setting. 1,2 Various systems have been used to assess … It will also assess future research needs on this important clinical topic. II. … investigator and a research staff member, who will use a clearly defined template and criterion to assess … The study may be missing information, making it difficult to assess limitations and potential problems … proportion of variation in study estimates due to heterogeneity) will be calculated as possible to assess

102. Insomnia_protocol-140403 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_protocol-140716.pdf
     April 03, 2014 - Additionally, a number of questionnaires have been developed to assess sleep and the impact on distress … Timing KQ1: Outcomes measured at 4 weeks to 3 months after initiation of treatment will be used to assess … Additional items will be developed to assess potential risk-of-bias not addressed by the Cochrane tool … We will assess the clinical and methodological heterogeneity and variation in effect size to determine … We will assess statistical heterogeneity with Cochran’s Q test and measure magnitude with I2 statistic

103. Insomnia_protocol-140403 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_research-protocol.pdf
     April 03, 2014 - Additionally, a number of questionnaires have been developed to assess sleep and the impact on distress … Timing KQ1: Outcomes measured at 4 weeks to 3 months after initiation of treatment will be used to assess … Additional items will be developed to assess potential risk-of-bias not addressed by the Cochrane tool … We will assess the clinical and methodological heterogeneity and variation in effect size to determine … We will assess statistical heterogeneity with Cochran’s Q test and measure magnitude with I2 statistic

104. Management of Postpartum Hemorrhage: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
     July 01, 2016 - e.g., hemoglobin and hematocrit), iron replacement therapy, transfusion, and other interventions to assess … surgical interventions, affects length of hospital stay. ��� Supportive care Evidence is insufficient to assess … For additional details on the methodology used to assess strength of evidence, please refer to: Owens

105. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
     November 18, 2024 - Methodology used to assess food and beverage intake of children and adults depends on the circumstance … Nutrient Databases Used to Assess Food and Nutrient Intakes Despite the limitations addressed above, … Dietary intake can be from foods, supplements, and/or supplemented foodsb • Studies that only assess … Otherwise, we will qualitatively assess the literature for indications of publication bias. … We will assess statistical heterogeneity of sensitivity and subgroup analyses (e.g., differences by

106. Supplemental Project to Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/transparency-tympanostomy/research

107. Supplemental Project to Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/transparency-tympanostomy

108. Meditation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
     October 17, 2012 - While both clinical and healthy populations use meditation, this report seeks to assess the impact of … However, prior reviews have tended to assess behavioral trials with the same bias measures used for … The study may have been missing information, making it difficult to assess limitations and potential … We will conduct sensitivity analyses by omitting one study at a time to assess the influence of any … Evid Rep Technol Assess (Full Rep). Jun 2007(155):1-263. 22. Chambless DL, Hollon SD.

109. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quality-gap-palliative-hospice_research-protocol.pdf
     June 27, 2011 - We will also assess other elements of study design that affect the applicability of the studies. … Grading the Evidence for Each Key Question At the completion of our review, we will assess the … We will assess the strength of the best available evidence, including the risk of bias in relevant … First, we will assess studies to ensure that they included a relevant palliative care population and … Evid Rep Technol Assess (Summ) 2004; (110):1-6. PMID: 15649108. 15.

110. Assessing Applicability: Interactive Case Study Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability-quiz.ppt
     October 08, 2025 - The process used to assess applicability and to distinguish efficacy trials from effectiveness trials … Using a three-step process to assess applicability can make the process easier.

111. Assessing Applicability: Interactive Case Study Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability-quiz.ppt
     October 08, 2025 - The process used to assess applicability and to distinguish efficacy trials from effectiveness trials … Using a three-step process to assess applicability can make the process easier.

112. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - These include questions to assess selection bias, confounding, performance bias, detection bias, and … In case data do not allow a quantitative approach, we will assess these questions qualitatively. … To assess publication bias, we will use funnel plots and Kendall’s tests, knowing that these tests have … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus … Health Technol Assess. 2005 Jul;9(26):1-134, iii-iv. PMID: 16014203. 29.

113. Supplemental Project To Assess the Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/transparency-omega-3/research

114. Supplemental Project To Assess the Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/transparency-omega-3

115. Healthcare Industry Waste and Lifecycle Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-protocol.pdf
     August 23, 2023 - material efficiency in processes and procedures.1-8 The framework for LCA is described in ISO 14040.9 To assess … Environmental Protection Agency to assess and limit the release of the air pollutant under the Clean … and practice, understand the components of those frameworks, and assess gaps in research and practice … Table 1 Potential Key Informant Questions Topic Question Guiding questions • To fully assess … Integr Environ Assess Manag. 2019 Jan;15(1):6-18. doi: 10.1002/ieam.4100. PMID: 30242966. 38.

116. Improving Medication Safety in High Risk Medicare Beneficiaries Toolkit (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
     July 01, 2012 - We chose a validated research tool to assess adverse drug events. … Brief Description: To assess symptoms potentially related to medications, patients in the MEDIS-MB … We chose a validated research tool to assess drug related problems. … The responses can be combined and summarized to assess the numbers and types of drug related problem … In addition, three questions were asked to assess overall satisfaction with healthcare received.

117. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
     January 10, 2012 - may not be translated or used; however, their existence will be noted in the report so readers can assess … Assessment of Methodological Quality of Individual Studies Predefined criteria will be used to assess … The study may be missing information, making it difficult to assess limitations and potential problems … Specificity"/ 12 "Reproducibility of Results"/ 13 or/6-12 14 (risk adj2 (factor$ or assess … Curve") S14 S7 or S8 or S9 or S10 or S11 or S12 or S13 S15 "risk factor*" S16 "risk assess

118. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - As a result, each EMS agency must assess what is feasible given its specific situation and environment … First, we will assess the effectiveness and potential harms of different blood transfusion and fluid … Finally, we will assess the literature about implementation of blood transfusion programs and protocols … As such, we will assess risk of bias for these study types, when possible, for all KQs. … Predefined criteria will be used to assess the quality of included studies.

119. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
     August 19, 2024 - Methodology used to assess food and beverage intake of children and adults depends on the circumstance … Nutrient Databases Used to Assess Food and Nutrient Intakes Despite the limitations addressed above, … fatty acid biomarker wt% of total or concentrations • Studies that only assess fatty acid intake … via infusions (parenteral [intralipid] or stable isotope) • Studies that only assess exposure to … Otherwise, we will qualitatively assess the literature for indications of publication bias.

120. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - We will use the same screening forms and inclusion/exclusion criteria to assess eligibility of citations … We will use an adapted version of the McMaster Quality Assessment Scale of Harms tool to assess harms … upon the quantity and size of the sources for the data, we may attempt to establish thresholds to assess … We will assess strength of evidence as stipulated in the Effective Health Care Program’s Methods Guide … We will assess reporting bias of randomized controlled trials by examining outcomes of trials as reported