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  1. 8 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - Do not assume studies adequately assess harms because methods used to assess and report benefits are … Such information has several potentially valuable uses: To assess the number of unpublished trials … Observational Studies Observational studies are almost always necessary to assess harms adequately … In addition, caution should be used when considering use of summary scores to assess risk of bias. … Do not assume studies adequately assess harms because methods used to assess and report benefits are
  2. 8 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - Do not assume studies adequately assess harms because methods used to assess and report benefits are … Such information has several potentially valuable uses: To assess the number of unpublished trials … Observational Studies Observational studies are almost always necessary to assess harms adequately … In addition, caution should be used when considering use of summary scores to assess risk of bias. … Do not assume studies adequately assess harms because methods used to assess and report benefits are
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - We will use data provided by the systematic review to assess strength of evidence for results without … Two investigators will independently assess risk of bias for all included studies. … We will assess harms as dichotomous variables to acknowledge the inherent difficulties of assessing … There are various ways to assess harms; each has problems. … We will assess strength of evidence for key final health outcomes measured with validated scales.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
    May 19, 2011 - Men with clinically localized prostate cancer (T1–T2), without (or unable to assess) either regional … Based on the final inclusion and exclusion criteria, we will assess the titles and/or abstracts of … We will assess the directness (direct or indirect) of the evidence. … We will assess the precision (precise or imprecise) of the evidence based on the degree of certainty … Assessing Applicability We will qualitatively assess the applicability of included studies to the
  5. effectivehealthcare-admin.ahrq.gov/products/mental-health-children/research
    March 01, 2020 - Related Research Report: Supplemental Project To Assess the Transparency of Reporting for Strategies … Improve Mental Health Care for Children and Adolescents (2017) Structured Abstract Objectives To assess
  6. effectivehealthcare-admin.ahrq.gov/products/methods-guidance-bias-individual-studies/methods
    October 01, 2019 - Assess risk of bias based on study design and conduct rather than reporting. … Design-Specific Criteria To Assess Risk of Bias We present design-specific criteria to assess risk … Many tools have emerged over the past 20 years to assess risk of bias. … Scales to assess the quality of randomized controlled trials: a systematic review. … Scales to assess the quality of randomized controlled trials: a systematic review.
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
    May 01, 2017 - Purpose of Review To assess effectiveness and safety of medical interventions for children with autism … We categorized studies as “other” if we could not assess strength of evidence for interventions and … We considered SOE to be insufficient to assess effects. N-acetylcysteine. … Data were inadequate to assess effects on other outcomes (insufficient strength of evidence). … Few studies reported data to assess time to effect of interventions.
  8. effectivehealthcare-admin.ahrq.gov/products/medication-therapy-management/research
    December 01, 2019 - MTM) interventions with comprehensive medication review, followup, education, and care coordination; assess … ) and patient characteristics ( KQ 4 ) that moderate the effect of an intervention on outcomes; and assess
  9. effectivehealthcare-admin.ahrq.gov/products/decision-models-guidance/methods
    April 01, 2021 - Health Technol Assess. 2004 Sep;8(36):iii-158. PMID: 15361314. … EUR-ASSESS Project Subgroup report on Methodology. … Health Technol Assess. 2009 Jan;13(8):iii, ix-50. PMID: 19203465. … Health Technol Assess. 2003;7:iii, ix-x, 1-51. PMID: 14609481. … Health Technol Assess. 1999;3(2):1-134. PMID: 10448202. Briggs AH.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
    December 20, 2011 - In order to determine whether quantitative analyses are appropriate, we will assess the clinical … Davidson Trauma Scale (DTS)29, 30 • 17-item, self-rating scale used to assess DSM-IV PTSD criteria … Impact of Events Scale (IES)31 • 15-item self-reported measure used to assess the frequency with … • It does not assess all of the 17 DSM symptoms of PTSD and includes items that are not directly … • Assess the severity of PTSD symptoms (consist of the same 17 items as the PSS- I).
  11. effectivehealthcare-admin.ahrq.gov/products/genitourinary-syndrome/protocol
    March 01, 2024 - Key Question 4: What is the appropriate follow-up interval to assess improvement, sustained improvement … Assess different durations of follow up   KQ5: Usual care, or different type or level of surveillance … Information from grey literature will also be used to assess publication and reporting bias and inform … We will use A Measurement Tool to Assess Systematic Reviews (AMSTAR) 2 criteria for systematic reviews … We will assess the clinical and methodological heterogeneity and variation in effect size to determine
  12. effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
    May 01, 2020 - Key Points Assess all important harms, whenever possible. … Do not assume studies adequately assess harms because methods used to assess and report benefits are … Such information has several potentially valuable uses: To assess the number of unpublished trials … Observational Studies Observational studies are almost always necessary to assess harms adequately. … Do not assume studies adequately assess harms because methods used to assess and report benefits are
  13. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - Developing instruments that accurately assess the effect of JIA on health and well- being is critical … to enable us to assess the overall impact of the disease and to quantify the efficacy of treatments. … Multiple instruments have been developed or adapted to assess severity of disease, disability, and quality … Multidimensional instruments appear to better assess outcomes. … Implementing more general disease-based registries could not only help assess risk but help evaluate
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
    July 01, 2010 - Criteria for Inclusion and Exclusion of Studies in the Review Two independent reviewers will assess … The study may be missing information, making it difficult to assess limitations and potential problems … Visual inspection of funnel plots and Egger’s weighted regression statistics will be used to assess … These analyses will also be conducted to assess the effect of trial inclusion criteria, patient demographics … We will assess whether or not the effect sizes were on the same side of unity; whether the range of
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-quality.ppt
    January 01, 2010 - Health Technol Assess 2003;7(27):iii-x, 1-173. … Health Technol Assess 2004;8(25):iii, 1-234. … criterion Adjudicate differences between raters in a transparent manner when two raters independently assess … Health Technol Assess 2003;7(27):iii-x,1-173. … Health Technol Assess 2004;8(25):iii, 1-234.
  16. effectivehealthcare-admin.ahrq.gov/products/fecal-incontinence/research-protocol
    December 01, 2019 - For RCTs, we will assess the risk of bias using a modified Cochrane Risk of Bias tool. 37 The seven … If the risk of bias assessment tool is similar to our approach, we will separately assess risk of bias … We will assess the heterogeneity among clinical, methodological and PICOTS elements to determine the … Evid rep/technol assess 2007; Dec;(161):1-379. PMID: 18457475. Clinic M. Fecal Incontinence. … Are statistical methods used to assess the primary outcome appropriate to the data?
  17. effectivehealthcare-admin.ahrq.gov/products/ems-blood-transfusion/protocol
    February 01, 2025 - As a result, each EMS agency must assess what is feasible given its specific situation and environment … First, we will assess the effectiveness and potential harms of different blood transfusion and fluid … Finally, we will assess the literature about implementation of blood transfusion programs and protocols … As such, we will assess risk of bias for these study types, when possible, for all KQs. … Predefined criteria will be used to assess the quality of included studies.
  18. effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-surveillance/research-protocol
    December 01, 2019 - Men with clinically localized prostate cancer (T1–T2), without (or unable to assess) either regional … We will assess the directness (direct or indirect) of the evidence. … We will assess the precision (precise or imprecise) of the evidence based on the degree of certainty … Assessing Applicability We will qualitatively assess the applicability of included studies to the U.S … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews.
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-protocol.pdf
    October 01, 2023 - randomized controlled trials [RCT], nonrandomized controlled studies, interrupted time series) To assess … Two reviewers will independently assess the risk of bias at the study and outcomes level. E. … To determine whether quantitative analyses are appropriate, we will assess the contextual, clinical, … Two trained reviewers will assess each domain for each key outcome, and differences will be resolved … Int J Technol Assess Health Care. 2012 Jan;28(1):36-43. doi: 10.1017/S0266462311000687.
  20. effectivehealthcare-admin.ahrq.gov/products/prostatic-hyperplasia-medications/research-protocol
    December 01, 2019 - There are two validated and widely used, nearly identical instruments used to assess LUTS, the American … Our review will comprehensively assess newer medications for LUTS/BPH newly used in the last 10 years … Information from grey literature will also be used to assess publication and reporting bias and inform … We will assess the clinical and methodological heterogeneity and variation in effect size to determine … We will assess strength of evidence for key final health outcomes measured with validated scales.

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