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  1. effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-performance/methods
    December 01, 2019 - test performance when the reference standard is imperfect: (a) to forgo the classical paradigm and assessAssess the index test’s ability to predict patient-relevant outcomes instead of test accuracy. … Assess the concordance of difference tests instead of test accuracy. … Assess the condordance in the results of the index and reference tests (i.e., treat them as two alternative … Health Technol Assess 2007; 11(50):iii, ix-51.
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/infantile-epilepsy-amended-protocol.pdf
    March 07, 2021 - We will assess the effectiveness, comparative effectiveness, and harms for each intervention to support … We will assess randomized trials for Key Question 1 and 2 using the Cochrane Risk of Bias 2 (ROB2) … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … Int J Technol Assess Health Care. 2006 Jul;22(3):288-94. PMID: 16984055. 8. … Primarily, while they support the effort of the systematic review to assess the effectiveness and risk
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
    September 27, 2022 - , and progressive muscle relaxation for migraine prevention in adults, but did not comprehensively assess … We will assess the risk of bias in each study included for a KQ. … We will assess randomized trials for Key Questions 1 and 2 using the Cochrane Risk of Bias 2 (ROB2) … Although we will assess selective outcome reporting, we will not incorporate it in the overall risk … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - higher risk for complications with invasive screening.4 Types of Noninvasive Technologies NITs can assess … have CAD and were not being tested for chest pain symptoms (e.g., postrevascularization testing to assess … While this focus was adequate for identifying studies to assess the diagnostic accuracy of the NIT … In order to assess sex differences in NIT diagnostic accuracy or the impact on clinical outcomes, a … Additional studies of the NIT modalities to assess differing symptomatology and timing at presentation
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/knowledge-brief-2-methods-public-deliberation-130213.pdf
    February 01, 2013 - often include process elements (e.g., whether participants had equal opportunities to contribute) to assess … However, it may be difficult to assess whether a specific deliberative event had a direct effect on … studies use both qualitative and quantitative methods to describe the deliberative activity and to assess
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/knowledge-brief-2-methods-public-deliberation-130213.pdf
    February 01, 2013 - often include process elements (e.g., whether participants had equal opportunities to contribute) to assess … However, it may be difficult to assess whether a specific deliberative event had a direct effect on … studies use both qualitative and quantitative methods to describe the deliberative activity and to assess
  7. effectivehealthcare-admin.ahrq.gov/products/asthma/protocol
    March 01, 2020 - Thus, the overarching goal of this project is to assess the current state of evidence of the processes … For eligible systematic reviews and guidelines, we will assess their quality and extract select key elements … We will use ROBIS to assess the quality of systematic reviews and the AGREE-II instrument to assess guidelines … ROBIS: A new tool to assess risk of bias in systematic reviews was developed.
  8. Slide 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/cf_intro_ehc_cf_overview_1012.pdf
    October 13, 2011 - ─ Assess what is known about public deliberation ─ Conduct a large randomized controlled experiment
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/lavallee-text.pdf
    October 13, 2011 - § Assess what is known about public deliberation § Conduct a large randomized controlled experiment
  10. effectivehealthcare-admin.ahrq.gov/products/transitions-care-pediatric-adult/protocol
    February 01, 2022 - in peer-reviewed journals and grey literature with full text available (if sufficient information to assess … For the key questions, we will assess the efficacy and comparative effectiveness of outcomes using minimal … We will assess the clinical and methodological heterogeneity and variation in effect size to determine … appropriateness of pooling data. 17 We will assess statistical heterogeneity with Cochran's Q test … We will assess strength of evidence for key final health outcomes measured with validated scales.
  11. effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research-protocol
    July 01, 2021 - We will assess the effectiveness, comparative effectiveness, and harms for each intervention to support … We will assess randomized trials for Key Question 1 and 2 using the Cochrane Risk of Bias 2 (ROB2) tool … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section … Int J Technol Assess Health Care. 2006 Jul;22(3):288-94. PMID: 16984055. … Primarily, while they support the effort of the systematic review to assess the effectiveness and risk
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
    October 05, 2018 - outcomes:  Primary: Incident radiographic vertebral fracture  Secondary: Change in BMD (Will assess … For each of these outcomes, two investigators will independently assess each study for bias in several … We will assess the clinical and methodological heterogeneity (participant population, intervention, … We will assess statistical heterogeneity with Cochran’s Q test and measure magnitude with I2 statistic … Based on these elements, we will assess the overall strength of evidence for each comparison and outcome
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
    January 01, 2020 - These include questions to assess selection bias, confounding, performance bias, detection bias, and … Two independent reviewers will assess risk of bias for each study. … When recent, relevant existing systematic reviews are identified for a particular outcome, we will assess … above, in cases where we identify a recent eligible meta-analysis for an eligible outcome, we will assess … ROBIS: A new tool to assess risk of bias in systematic reviews was developed.
  14. effectivehealthcare-admin.ahrq.gov/products/breastfeeding/research-protocol
    October 01, 2019 - These include questions to assess selection bias, confounding, performance bias, detection bias, and … Two independent reviewers will assess risk of bias for each study. … When recent, relevant existing systematic reviews are identified for a particular outcome, we will assess … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus … ROBIS: A new tool to assess risk of bias in systematic reviews was developed.
  15. effectivehealthcare-admin.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
    January 01, 2021 - applicability of the evidence to primary care; (3) to assess whether some medications are more or less … based on the AHRQ Methods Guide for Comparative Effectiveness Reviews , 40 including questions to assess … Two independent reviewers will assess risk of bias for each study. … To assess statistical heterogeneity, we will calculate the chi-squared statistic and the I 2 statistic … Two reviewers will assess each domain for each key outcome, and differences will be resolved by consensus
  16. effectivehealthcare-admin.ahrq.gov/products/dietary-protein-intake/protocol
    December 01, 2023 - Information from these sources will be used to assess publication and reporting bias and inform future … We will first describe the results in evidence tables, and then assess the clinical and methodological … 25 We will identify heterogeneity (inconsistency) through visual inspection of the forest plots to assess … the amount of overlap of CIs and the I 2 statistic, which quantifies inconsistency across studies to assess … Thus, including all metabolic studies that assess protein or amino acid requirements, regardless of HDI
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
    July 01, 2012 - Assess whether modeling may be useful. … Step 3: Assess whether modeling could be useful in the PET and AD evidence report. … Step 4: Assess whether prior modeling studies could be utilized. … Health Technol Assess 2004; 8(36):iii-xi, 1. 13. … Health Technol Assess 2007; 11(52):iii-xi, 1. 26.
  18. effectivehealthcare-admin.ahrq.gov/products/cerebral-palsy-feeding/research-protocol
    December 01, 2019 - We will assess the quality of systematic reviews using the AMSTAR measurement tool (Appendix B). … Assessment of Methodological Risk of Bias of Individual Studies We will assess the quality of studies … For case series, we will use a tool adapted from EPC work to develop methods to assess risk of bias. … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. … For the pooled results, a test should be done to ensure the studies were combinable, to assess their
  19. effectivehealthcare-admin.ahrq.gov/products/breastfeeding-health-outcomes/protocol
    February 01, 2025 - Once the title and abstract screening stage is complete, two reviewers will independently assess the … Assessment of Methodological Risk of Bias of Systematic Reviews and Individual Studies We will assess … Two independent reviewers will assess the risk of bias for each primary study. … this domain as part of our rating. 43 , 53 , 54 We may assess additional domains when appropriate, … Evid Rep Technol Assess (Full Rep). 2007(153):1-186. U. S.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
    February 03, 2025 - Once the title and abstract screening stage is complete, two reviewers will independently assess the … Assessment of Methodological Risk of Bias of Systematic Reviews and Individual Studies We will assess … Two independent reviewers will assess the risk of bias for each primary study. … The primary domains we will assess as part of our SOE assessment are study limitations, directness, … Evid Rep Technol Assess (Full Rep). 2007(153):1-186. 23. U. S.

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