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  1. effectivehealthcare-admin.ahrq.gov/products/vitamin-d-calcium/research-protocol
    December 01, 2019 - roles in preventing acute deficiency states) and physicians’ increasing use of laboratory tests to assess … The update report will assess all outcomes assessed in the original 2009 report with the exception of … To assess the status of ongoing and recently completed trials, we will search ClinicalTrials.gov. … We will also assess the reporting of intention-to-treat analyses and crossovers when so designed, as … Ont Health Technol Assess Ser [Internet]. 2010 Feb:10(2):1-95. Accessed on January 03, 2013.
  2. effectivehealthcare-admin.ahrq.gov/products/pressure-ulcer-prevention/research-protocol
    December 01, 2019 - may not be translated or used; however, their existence will be noted in the report so readers can assess … Assessment of Methodological Quality of Individual Studies Predefined criteria will be used to assess … The study may be missing information, making it difficult to assess limitations and potential problems … Sensitivity and Specificity"/ 12 "Reproducibility of Results"/ 13 or/6-12 14 (risk adj2 (factor$ or assess … S13 (MH "ROC Curve") S14 S7 or S8 or S9 or S10 or S11 or S12 or S13 S15 "risk factor*" S16 "risk assess
  3. effectivehealthcare-admin.ahrq.gov/products/labor-nitrous-oxide/research-protocol
    December 01, 2019 - as being less expensive and invasive than widely used regional anesthesia, this review attempts to assess … Assessment of Methodological Quality of Individual Studies Assess Study Quality. … Grading the Evidence for Each Key Question Assess the Strength of Evidence. … Assessing Applicability Our team will assess the applicability of findings reported in the included … The Newcastle-Ottawa scale will be utilized to assess the quality of nonrandomized and observational
  4. effectivehealthcare-admin.ahrq.gov/products/long-term-care-adults/research-protocol
    December 01, 2019 - Data elements will also include descriptors to assess methodological quality and study applicability. … We will assess methodological quality of individual studies for each key question using criteria specific … We will assess the strength of evidence for each key question using the approach described in the EPC … We will evaluate individual domains listed above qualitatively and assess a summary rating of “high,” … Assessing Applicability To assess applicability of individual studies, we will assess the eligibility
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
    June 01, 2010 - • This paper provides a framework for decisionmaking on the inclusion of observational studies to assess … effects in comparative effectiveness reviews • Comparative effectiveness reviewers should routinely assessAssess the risk of bias of observational studies to answer the gap review questions. … Assess whether observational studies address the review questions. … Health Technol Assess 2003;7:iii-x, 1- 173. 10. West S, King V, Carey TS, et al.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
    June 01, 2010 - • This paper provides a framework for decisionmaking on the inclusion of observational studies to assess … effects in comparative effectiveness reviews • Comparative effectiveness reviewers should routinely assessAssess the risk of bias of observational studies to answer the gap review questions. … Assess whether observational studies address the review questions. … Health Technol Assess 2003;7:iii-x, 1- 173. 10. West S, King V, Carey TS, et al.
  7. effectivehealthcare-admin.ahrq.gov/products/coronary-stents-effectiveness/abstract
    December 01, 2019 - Aim 4: Assess if the effectiveness of CAS versus CEA differ among subgroups. … Aim 5: Assess the impact of unmeasured confounding in a well-designed comparative effectiveness study
  8. effectivehealthcare-admin.ahrq.gov/products/cognitive-decline/research-protocol
    December 01, 2020 - We will assess the effects by the duration of followup, especially the lag between the end of treatment … We will attempt to assess subgroups defined by drug classes and non-pharmacological treatment. … Two investigators will independently assess risk of bias for all eligible studies. … appropriateness of pooling data. 16 We will assess statistical heterogeneity with Cochran's Q test … We will assess strength of evidence for key final health outcomes measured with validated scales.
  9. effectivehealthcare-admin.ahrq.gov/products/methods-guidance-de-novo-processes/methods
    December 01, 2019 - Once EPCs have established relevance for an existing SR, they should assess and rate quality using the … , we recommend: At least two independent reviewers should assess SRs for quality. … Determining specific criteria to assess the quality of individual patient data meta-analyses. … Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. … Health Technol Assess 2003;7:1-76. 21. Moher D, Pham B, Klassen TP, et al.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
    November 09, 2011 - The analysis will assess the evidence of the effectiveness of new safe practices and the adoption of … Questions Considering the above goals for the project, the first step we needed to perform was to assessAssess the effect of the patient safety practice on outcomes and possible unexpected effects, including … For studies with multiple intervention sites, assess the influence of context on the effectiveness of
  11. effectivehealthcare-admin.ahrq.gov/about/epc/review
    July 01, 2024 - evidence reports, including: Internal review by Agency for Healthcare Research and Quality (AHRQ) staff to assess … adherence to EPC Program expectations Review by an EPC associate editor to assess adherence to established
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
    June 01, 2015 - Intervention • Studies to assess the intensity of CM including whether the frequency of CM contacts, … • Assess potential ways to standardize CM. … • Assess the impact of the use of information technology on the effectiveness of CM. … • Assess which resource utilization is the primary outcome for CM. … • Assess how CM can be incorporated into Accountable Care Organizations.
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0398_06-17-2008.pdf
    January 01, 2008 - erythrocytes or reticulocyte hemoglobin content in relation to other measures of iron metabolic status to assess …  The two traditional tests used to assess serum iron status are TSAT and serum ferritin.
  14. Untitled (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
    February 25, 2016 - The Glasgow Coma Scale (GCS)3,4 is a widely-used instrument to assess consciousness at the site of injury … The aims of this review are to assess the predictive utility, reliability, and ease of use of the tGCS … Key Question 1 does not directly assess the utility of the tGCS compared with the mGCS for predicting … Two investigators will independently assess risk of bias for each study. … The study may also be missing information, making it difficult to assess limitations and potential
  15. effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/research-protocol
    December 01, 2019 - We will assess the comparative effectiveness of surgical or pharmacologic interventions after initial … We will, however, re-assess non-English studies as we update our MEDLINE search. … Assessment of Methodological Risk of Bias of Individual Studies We will assess the risk of bias of … We will assess key outcomes of interest specified in the PICOTS above using criteria from established … We will include the questions/tools used to assess the risk of bias of all studies as an appendix to
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
    September 24, 2024 - First, we will assess the effectiveness and potential harms of different blood transfusion and fluid … Finally, we will assess the literature about implementation of blood transfusion programs and protocols … As such, we will assess risk of bias for these study types, when possible, for all KQs. … Predefined criteria will be used to assess the quality of included studies. … To assess whether pairwise meta-analysis will be appropriate for KQ1–5, we will consider population
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/worker-health_executive.pdf
    April 01, 2016 - Risk-of-Bias Assessment To assess the risk of bias (internal validity) of studies eligible for KQ 2, … These criteria included questions to assess selection bias, confounding, performance bias, detection … To assess publication bias, we looked for evidence of unpublished literature through searches of gray … We also reviewed, when available, the original protocols for included trials to assess for selective … We could not assess whether strategies were more or less effective based on their complexity (single
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
    October 10, 2019 - For the outcomes functional status and quality of life we will assess whether the outcome assessment … For each risk-of-bias criterion, we will assess high, moderate or unclear, and low risk of bias. … Specifically, we will assess whether combination treatments of WBRT plus SRS are more effective than … The suitability evaluation will assess homogeneity, transitivity, and consistency of the data. … To assess transitivity, we will establish the available connections for each review question and the
  19. effectivehealthcare-admin.ahrq.gov/products/radiation-brain-metastases/protocol
    June 01, 2021 - The reporting will also assess whether adverse events, including serious adverse events, were defined … For each risk-of-bias criterion, we will assess high, moderate or unclear, and low risk of bias. … Specifically, we will assess whether combination treatments of WBRT plus SRS are more effective than … The suitability evaluation will assess homogeneity, transitivity, and consistency of the data. … To assess transitivity, we will establish the available connections for each review question and the
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
    June 10, 2024 - the quality of adverse events reporting.110, 111 We will assess the six domains selection, detection … The McHarm tool is designed to directly assess the rigor of the adverse event assessment (e.g., use … We will assess heterogeneity using graphical displays and the I-squared statistics. … We will assess the potential for publication bias for all key outcomes using the Begg and the Egger … We will assess whether studies used inadequate intervention or substandard care as comparators.

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