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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - • Few studies compared other antidepressants
to placebo or to each other, or reported other
outcomes … The objective
of this review is to assess comparative adverse
effects of pharmacologic antidepressants … Adverse events of antidepressants versus placebo or no therapy: summary
statements based on findings … Adverse events of antidepressants versus placebo or no therapy: summary
statements based on findings … Adverse events of antidepressants versus placebo or no therapy: summary
statements based on findings
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effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/research
April 16, 2020 - term, improvement in pain and function was small with specific anticonvulsants, moderate with specific antidepressants … of benefit for memantine in fibromyalgia and for serotonin norepinephrine reuptake inhibitor (SNRI) antidepressants … neuropathic pain, pregabalin/gabapentin for fibromyalgia), serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants … Dose viii reductions reduced the risk of some adverse events with SNRI antidepressants. … In the short term, small improvements in pain and/or function were seen with SNRI antidepressants for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
August 06, 2018 - Agents, Second-Generation"[MeSH] OR "Serotonin
Uptake Inhibitors"[MeSH] OR "Antidepressive Agents"[ … Agents, Second-Generation/adverse effects"[Mesh]
OR "Antidepressive Agents, Second-Generation/poisoning … Agents, Second-Generation"] or [mh "Serotonin Uptake
Inhibitors"] or [mh "Antidepressive Agents"] or … Agents, Second-Generation"/AE] or [mh "Antidepressive
Agents, Second-Generation"/PO] or [mh "Antidepressive … Agents, Second-Generation” AND
“adverse effects”) OR (MH "Antidepressive Agents,
Second-Generation
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0352_09-22-2010.pdf
January 01, 2010 - interested in the comparative maternal and fetal benefits and harms of
treatment of depression with antidepressants … have mild, moderate, or severe depression and are pregnant
Intervention(s): Continuing treatment with antidepressants … Comparator(s): Discontinuing, combining, tapering, or switching classes of treatment
with antidepressants … the comparative harms or benefits for both fetus/infant and the mother of
continuing treatment with antidepressants
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effectivehealthcare.ahrq.gov/products/back-pain-treatment/clinician
November 15, 2016 - . §§ Other antidepressants that were evaluated included tricyclic antidepressants, selective serotonin … reuptake inhibitors, and tetracyclic antidepressants. … --duloxetine
Placebo
Pain, function
3 RCTs
+
[evidence medium]
Other antidepressants §§ … It is unclear whether antidepressants might have additional effects on mood in patients with low back … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - Placebo Pain, function 3 RCTs + ���
Other antidepressants§§ Placebo Pain 2 SRs − ���
+ = small effect … that were evaluated included tricyclic antidepressants, selective serotonin reuptake inhibitors, and … tetracyclic antidepressants. … Interventions:
�� Most trials of antidepressants excluded patients
with depression or only included … It is unclear whether antidepressants might
have additional effects on mood in patients with low
back
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-disposition-mental-health-pregnancy_0.pdf
June 01, 2021 - By medication class, we found
studies covering antidepressants (6); antipsychotics (2); SUD (opioids … This is especially true for harms of
antidepressants, and specifically for SSRIs. … The effect of antidepressants on
fertility. … Antidepressants
during pregnancy and autism in offspring: population based cohort study. … Aripiprazole augmentation of antidepressants for
postpartum depression: a preliminary report.
-
effectivehealthcare.ahrq.gov/health-topics/a
Disorders
Amyloidosis
Anemia
Anemia
Angina
Angioplasty
Antibiotic Resistance
Antibiotics
Antidepressants
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_consumer.pdf
May 01, 2016 - Second-generation
antidepressants
�� These medicines were made to treat depression,
but they are also … used to treat other conditions.
�� Examples of second-generation antidepressants
include bupropion … Warning: The FDA warns that second-generation antidepressants may cause thoughts of suicide or
suicidal … Lisdexamfetamine (Vyvanse®)
Topiramate (Topamax®, Trokendi XR®, Qudexy® XR)
Second-generation antidepressants … Note: The side effects listed here are common side effects of second-generation antidepressants.
-
effectivehealthcare.ahrq.gov/products/mental-health-pregnancy/protocol
January 11, 2019 - Use of antidepressants during pregnancy? … : what to consider when weighing treatment with antidepressants against untreated depression. … Anticonvulsants[Mesh] OR Anticonvulsants[Pharmacological Action] OR anticonvulsant OR anticonvulsants OR "Antidepressive … Agents"[MeSH] OR "Antidepressive Agents, Second-Generation"[MeSH] OR anti-depress* OR antidepressant … * OR antidepressive* OR "antidepressive agent" OR "antidepressive agents" OR "antidepressive drug" OR
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - Use of antidepressants during pregnancy? … : what to consider
when weighing treatment with antidepressants against untreated depression. … Anticonvulsants[Mesh] OR Anticonvulsants[Pharmacological Action] OR
anticonvulsant OR anticonvulsants OR "Antidepressive … Agents"[MeSH] OR
"Antidepressive Agents, Second-Generation"[MeSH] OR anti-depress* OR
antidepressant … * OR antidepressive* OR "antidepressive agent" OR "antidepressive
agents" OR "antidepressive drug" OR
-
effectivehealthcare.ahrq.gov/products/binge-eating/consumer
May 24, 2016 - Second-generation antidepressants
These medicines were made to treat depression, but they are also … Examples of second-generation antidepressants include bupropion (Wellbutrin®), citalopram (Celexa®), … lisdexamfetamine (Vyvanse®), topiramate (Topamax®, Trokendi XR®, Qudexy® XR), and second-generation antidepressants … Second-generation antidepressants
Nausea and vomiting
Sweating
Trouble falling asleep or staying … Warning : The FDA warns that second-generation antidepressants may cause thoughts of suicide or suicidal
-
effectivehealthcare.ahrq.gov/products/acs-depression/research-protocol
August 31, 2016 - Such treatments include pharmacotherapy and psychotherapy, with second generation antidepressants and … Many antidepressants have cautions for use in patients with angle-closure glaucoma, bipolar disorder, … "psychiatric disorder"[tiab] OR "psychiatric disorders"[tiab]
#4
"Depression/therapy"[Mesh] OR "Antidepressive … Agents"[Mesh] OR "Antidepressive Agents" [Pharmacological Action] OR "Antidepressive Agents, Tricyclic … " [Pharmacological Action] OR "Antidepressive Agents, Second-Generation" [Pharmacological Action] OR
-
effectivehealthcare.ahrq.gov/products/binge-eating/clinician
May 24, 2016 - Other commonly used pharmacological interventions include anticonvulsants and antidepressants. … [evidence high]
Second-generation antidepressants (as a class) vs. placebo
8 (MA c )
416
Antidepressants … [evidence high]
7 (MA c )
331
Antidepressants decreased the frequency of binge-eating episodes … [evidence high]
3 (MA c )
122
Antidepressants decreased the frequency of binge-eating days per … Lisdexamfetamine and second-generation antidepressants are classified as pregnancy category C.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
May 01, 2016 - Other commonly used pharmacological interventions include
anticonvulsants and antidepressants. … (as a class)
vs. placebo
8 (MAc) 416 Antidepressants increased binge-eating abstinence (RR 1.67; 95% … CI 1.24 to 2.26). ���
7 (MAc) 331 Antidepressants decreased the frequency of binge-eating episodes per … week (MD
-0.67; 95% CI -1.26 to -0.09).
���
3 (MAc) 122 Antidepressants decreased the frequency of … Lisdexamfetamine
and second-generation antidepressants are classified as pregnancy
category C.
�� There
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
November 01, 2017 - Post-ACS Treatment Strategies
Pharmacologic treatments included second-generation
antidepressants ( … (1 study), antidepressants only (1 study)
Comparator: Usual care
Primary outcome: Decrease in depression … Importantly, these trials use second-
generation antidepressants and/or cognitive behavioral
therapy … Thus, recommendations should be limited to these
interventions and not generalized to all antidepressants … (e.g., tricyclic antidepressants), which may have adverse
cardiovascular effects.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
July 08, 2014 - evidence on the risk
of neonatal withdrawal symptoms or pulmonary hypertension with
maternal use of antidepressant … drugs to treat depression during
pregnancy.” … A reader might interpret this to mean that
antidepressants are not effective during pregnancy. … The reviewed studies likely did not seek to
prove the effectiveness of antidepressants with pregnant … The Gartlehner review certainly establishes the comparative
effectiveness of antidepressants compared
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - Association between antidepressants and fall‐related injuries
among long‐term care residents. … and residual
confounding, so differences in characteristics between patients
prescribed different antidepressant … drugs that could account for
some of the associations between the drugs and the adverse
outcomes may … The study also found that SSRIs and
several other antidepressants were associated with an
increased … Management of depression in
the elderly by general practitioners: Antidepressants.
-
effectivehealthcare.ahrq.gov/products/acs-depression/research-review-final
November 14, 2017 - One trial compared second-generation antidepressants with usual care and found no effect on depression … although, when combined with studies included in the original review, it showed a small positive effect of antidepressants … Enhanced care interventions and a strategy using CBT plus second-generation antidepressants for patients
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
April 01, 2016 - ,
which found that CBT was more effective than ECT or
antidepressants alone for sustained response … Nearly all participants
continued antidepressants during the trial. … Nearly all participants continued
antidepressants during the trial. … Nearly all participants
continued antidepressants
during the trial. … Nearly all participants
continued antidepressants
during the trial.