-
effectivehealthcare.ahrq.gov/products/stroke-afib-update/research-protocol
July 07, 2017 - Newer anticoagulants (direct oral anticoagulants [DOACs]) resulted in reduced stroke and bleeding events … Procedural interventions
Procedural interventions for stroke prophylaxis have emerged and are growing … with AF are uncertain
There is a lack of information to guide decisions regarding the best specific anticoagulant … Oral Anticoagulant Prescription in Patients With Atrial Fibrillation and a Low Risk of Thromboembolism … pradaxa[tiab] OR heparin[tiab] OR apixaban[tiab] OR eliquis[tiab] OR edoxaban[tiab] OR lixiana[tiab] OR anticoagulant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - Similarly, we included antiplatelet agents aspirin and
clopidogrel; as well as the anticoagulant warfarin … We also
included dabigatran, a recently approved oral anticoagulant
that directly inhibits thrombin … A study
of extended prophylaxis versus inpatient prophylaxis
suggested that continuing enoxaparin therapy … Rare events such as bleeding
from prophylactic doses of anticoagulant are difficult to
answer in trials … Parenteral anticoagulants:
Antithrombotic Therapy and Prevention of Thrombosis, 9th ed:
American College
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - Newer anticoagulants (direct oral
anticoagulants [DOACs]) resulted in reduced stroke and bleeding events … of studies have examined the appropriate populations and appropriate
therapies for adequate stroke prophylaxis … Procedural interventions Procedural interventions for stroke prophylaxis have emerged and
are growing … AF are uncertain
• There is a lack of information to guide decisions regarding the best specific
anticoagulant … Oral Anticoagulant Prescription in Patients With Atrial
Fibrillation and a Low Risk of Thromboembolism
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - We have added explicit clarification regarding the FDA approval status of
the new anticoagulant drugs … agents (dabigatran, apixaban,
rivaroxaban) are not specific to apixaban. … Aspirin is not recommended for stroke prophylaxis in
AFib. … agents when compared with warfarin
(low strength of evidence). … Yet
in the last Key Point (page 49), the report implied
that all new anticoagulant agents are comparable
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - 2
A variety of strategies to prevent VTE are available,
including pharmacological (antiplatelet, anticoagulant … strategies with no VTE prophylaxis,
within and between classes of VTE prophylaxis modalities,
and … duration of VTE prophylaxis in patients undergoing
these surgeries; and the efficacy of VTE prophylaxis … Comparisons of mechanical VTE
prophylaxis versus no VTE prophylaxis did not provide
strong evidence … low SoE data on the
comparative effectiveness of aspirin or mechanical devices
with LMWH or other anticoagulants
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - 2
A variety of strategies to prevent VTE are available,
including pharmacological (antiplatelet, anticoagulant … strategies with no VTE prophylaxis,
within and between classes of VTE prophylaxis modalities,
and … duration of VTE prophylaxis in patients undergoing
these surgeries; and the efficacy of VTE prophylaxis … Comparisons of mechanical VTE
prophylaxis versus no VTE prophylaxis did not provide
strong evidence … low SoE data on the
comparative effectiveness of aspirin or mechanical devices
with LMWH or other anticoagulants
-
effectivehealthcare.ahrq.gov/products/thromboembolism-update/research-protocol/
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - Cook DH, Reeve BK, et al. (1996)
Stress Ulcer Prophylaxis in
Critically ill patients: resolving
discordant … discrepancies in four previous
systematic reviews and provide
estimates of the effect of stress ulcer
prophylaxis … Intervention
Intervention
described as
anticoagulants
Reviewer must make the decision on
which … interventions are considered
anticoagulants; e.g., may combine
oral and injectable anticoagulants. … Stress ulcer prophylaxis in critically ill
patients. Resolving discordant meta-
analyses.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-1-year-final-report-updated-title_0.pdf
May 01, 2024 - Reducing Adverse Drug Events Related to Anticoagulant Use in Adults ............................ 26 … infections
• Use of real-time ultrasound for central line
placement
• Interventions to improve prophylaxis … Reducing Adverse Drug Events Related to Anticoagulant
Use in Adults
9a. … The report found insufficient evidence on
covered dosing protocols and nomograms for newer anticoagulants … Reducing Adverse Drug Events Related to Anticoagulant Use in Adults
9a.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - acquired clotting factor defects
Disease states where impaired coagulation is but one manifestation
Anticoagulant … Episodic use where anticoagulant therapy contributes to bleeding problems beyond what would exist otherwise … For example, the bar representing the overall use of rFVIIa spans the entire range of potential uses—prophylaxis … Overview of rFVIIa Use for Pediatric Cardiac Surgery
A total of 40 patients received rFVIIa prophylaxis
-
effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - acquired clotting factor defects
Disease states where impaired coagulation is but one manifestation
Anticoagulant … Episodic use where anticoagulant therapy contributes to bleeding problems beyond what would exist otherwise … For example, the bar representing the overall use of rFVIIa spans the entire range of potential uses—prophylaxis … Overview of rFVIIa Use for Pediatric Cardiac Surgery
A total of 40 patients received rFVIIa prophylaxis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - • Concomitant medication use includes
anticoagulants.
3. … Concomitant anticoagulant use
• Concomitant use of anticoagulants (e.g., warfarin)
and any nonselective … NSAID increases the risk of
GI bleeding three- to sixfold compared to
anticoagulants alone … • Reliable conclusions about the safety of selective
NSAIDs used with anticoagulants are not possible … • Given the large number of patients who meet
criteria for aspirin prophylaxis for CV events,
more
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - Concomitant anticoagulant use Moderate overall: Primarily
observational studies
Concomitant use of anticoagulants … and nonselective
NSAIDs increases the risk of GI bleeding three- to six-
fold compared with anticoagulant … comparative safety of
nonselective, partially selective, and COX-2 selective
NSAIDs with concomitant anticoagulants … increased the risk of bleeding compared with
warfarin alone in patients with indications for
antithrombotic prophylaxis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sickle-cell-dental-rapid-response.pdf
July 01, 2024 - Further, antibiotic prophylaxis is recommended for invasive dental and major oral
surgical procedures … PubMed search history on November 30, 2023
Search
Number
Query Results
1 "Dental Prophylaxis"[ … Antibiotic prophylaxis is
recommended for
invasive dental and
major oral surgical
procedures. … Towards New Frontiers of Direct Oral Anticoagulants: Sickle Cell Disease
Acta Haematol, 142(4), 195- … Effects of antiplatelet and anticoagulant medications on the vasoocclusive
and thrombotic complications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - of
spine; Fever;
Juvenile rheumatoid
arthritis;
Myocardial infarction;
Myocardial infarction;
Prophylaxis … flurbiprofen Elimination half-life
range- 3.36 to 11.55
hrs
Constricted pupil,
intraoperative
prophylaxis … agents
Rofecoxib=35.3%
Celecoxib=21.9%
p<0.0001
(a)
Cardiovascular
TE
(b)
Cerebrovascular … agents
(a) 1.04 (0.50, 2.17)
(b) 1.43 (0.86, 2.38)
(c) 0.36 (0.01, 1.34)
n/a (a) increased risk … associated with age,
sex, cc aspirin use, cc
antiplatelet/anticoagulant
agents
(b) increased risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemophilia-dental-rapid-response.pdf
July 01, 2024 - In dental procedures that required local anesthesia, it was
recommended that children on routine prophylaxis … for factor therapy differed for adults versus
children—it was recommended that children on routine prophylaxis … PubMed search history on November 30, 2023
Search
Number
Query Results
1 "Dental Prophylaxis"[ … 3] OR "dental extraction"[Title/Abstract:~3] OR "dental
extractions"[Title/Abstract:~3] OR "dental prophylaxis … Spanish consensus
guidelines on prophylaxis with bypassing agents for surgery in patients with haemophilia
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
May 01, 2010 - Pediatric cardiac surgery
A total of 40 patients received rFVIIa prophylaxis in
one poor quality RCT
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - concomitant
prescription drugs from, on average,
5.9 different drug classes for primary and
secondary prophylaxis … : 40-55 years
Mixed gender
Unclear CHD risk
6-25 weeks treatment
INR Vitamin K (150 μg /day) + Anticoagulants … combination
with antiplatelet agents (acetylsalicylic acid,65,66
clopidogrel,67 or ticlopidine68), an anticoagulant … Overall evidence indicates that supplementation with
vitamin K may improve the stability of anticoagulant … or
withdrawal due to adverse events.41 This study recruited
70 participants with indications for anticoagulant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
January 01, 2015 - Antibiotic prophylaxis for bacterial
infections in afebrile neutropenic patients
following chemotherapy … Antimicrobial
prophylaxis for colorectal surgery.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
January 01, 2019 - neurocysticercosis: albendazole and
praziquantel
2006 Ann Intern
Med
17310052 Meta-analysis: anticoagulant … prophylaxis to prevent symptomatic
venous thromboembolism in hospitalized medical patients
2007 Ann … osteoarthritis of the knee or hip 2007 Ann Intern
Med
19666987 Neuraminidase inhibitors for treatment and prophylaxis