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effectivehealthcare.ahrq.gov/products/procalcitonin/research-protocol
April 26, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the increasing … problem of antibiotic resistance. … Intermediate outcomes—such as antibiotic exposure, duration of antibiotic therapy, length of stay, and … Discriminate use of antibiotics for exacerbation of COPD. Curr Opin Pulm Med 2009;15:126-32. … leukocytosis, pyuria), as described in guidelines
The comparator is specified as
initiation of antibiotics
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effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-3rdplace_tympanic.pdf
January 26, 2013 - United States, viral and bacterial ear infections are the most common childhood illnesses treated with
antibiotics … Ceftriaxone, Cefdinir, Cefixime) (9)
Potential negative outcomes of antibiotic use:
1. … Antibiotic resistance
2. Allergic reactions
3. … Fluoroquinolone antibiotics are preferred due to their lack of ototoxicity (7). … If the infection appears to be more
than just localized then oral and sometimes even parenteral antibiotics
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - of antibiotics or
pain related to ear drops. … oral antibiotics and watchful waiting or placebo. … , topical antibiotic-glucocorticoid drops are superior to oral antibiotics and there is a
suggestion … drops vs. systemic antibiotics or watchful waiting
Topical antibiotic-glucocorticoid drops are superior … to oral
antibiotics in achieving clinical cure
Topical antibiotic drops are superior to oral antibiotics
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/questions-what-are-the-appropriate-indications-for-tonsillectomy-recurrent-infections-how-many-sleep-disordered-breathingshould-clinicians-administer-or-prescribe-perioperative-antibiotics-to-children-undergoing-tonsillectomy
August 20, 2014 - infections how many Sleep disordered breathingShould clinicians administer or prescribe perioperative antibiotics … Throat infections are a common reason to see a primary care physician and often result in antibiotic … treatment.1 The cost of outpatient visits and the medications prescribed for sore throats including antibiotics … Children with SDB compared with controls have a significantly higher rate of antibiotic use 40 more hospital … validated instruments.12 These children suffered fewer infections after surgery resulting in fewer antibiotics
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effectivehealthcare.ahrq.gov/products/venous-ulcers-treatment/research-protocol
March 05, 2012 - Antibiotics
Antibiotic use is prevalent in the management of skin ulcers, even in the absence of clinical … The indications for the use of systemic or topical antibiotics are not defined, but antibiotics have … , peripherally inserted central catheter (PICC) line and access infections
Promotion of antibiotic … Potential systemic antibiotic treatment options for chronic venous ulcers
See Table 2 for a list … of antibiotics.
-
effectivehealthcare.ahrq.gov/products/venous-ulcers-treatment/research
January 27, 2014 - Abstract
Objectives
To systematically review whether the use of advanced wound dressings, systemic antibiotics … We found insufficient evidence evaluating the benefits and harms of the routine use of antibiotics.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - Antibiotics that disturb colon flora enough to
allow CDI to develop must get into the colon, and they … the likelihood that the
recommended antibiotics might induce CDI. … While several studies found increased risk with specific
antibiotics or antibiotic classes, the antibiotics … Identifying
new antibiotics may be one approach. … Impact of a
reduction in the use of high-risk antibiotics on the
course of an epidemic of Clostridium
-
effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - (Strong
recommendation, high-quality evidence)
• In patients in whom oral antibiotics cannot reach … therapy directed against the underlying
infection or who require retreatment with antibiotics shortly … • A prolonged course of oral antibiotics is acceptable therapy for recurrent or resistant disease … repeated antibiotic treatment, fecal transplantation in
combination with oral antibiotic treatment is … Antibiotics remain the mainstay of
treatment recommendations for mild-moderate CDI, with consideration
-
effectivehealthcare.ahrq.gov/sites/default/files/deliberative-methods-facilitation-slides-text.pdf
January 11, 2017 - o Decisions grounded in personal/societal values
Slide 7
The overuse of antibiotics … patients
o What information might be useful to convey to the public about the risk of
overusing antibiotics … Slide 8
The overuse of antibiotics: deliberative session
• Question: should there be more specific … limits on how doctors use antibiotics?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - Of note is that recommendations to increase dosing
levels for many antibiotics were included in the … In addition, therapeutic drug monitoring (TDM)
is only performed for a few selected antibiotics in practice … There was a lack of data to support the use of continuous
infusion of betalactam antibiotics compared … Again, readers of such a review are
likely looking for guidance on dosing antibiotics for multi-
drug … resistant organisms, or organisms with high MICs to
traditional antibiotics.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the
increasing … problem of antibiotic resistance. … Discriminate use of antibiotics for exacerbation of COPD. … leukocytosis,
pyuria), as
described in
guidelines
The comparator is specified as initiation
of antibiotics … as described in
guidelines to clarify the true comparator
for procalcitonin-guided initiation of
antibiotics
-
effectivehealthcare.ahrq.gov/products/c-diff-infections/research-protocol
May 24, 2010 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. … Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review.
-
effectivehealthcare.ahrq.gov/products/tympanostomy-tubes/research-protocol
November 18, 2015 - tympanostomy tubes for children with otitis media, indications for tympanostomy in children, prescription of antibiotics … for tube candidacy. 1 The American Academy of Pediatrics CPG discourages routine use of prophylactic antibiotics … drops versus systemic antibiotics or watchful waiting on duration of otorrhea, quality of life, or need … prophylaxis
KQ 5: Ototopical preparations
Ototopical antibiotics
FDA approved (i.e., ofloxacin … for recurrent episodes of AOM
Prophylactic antibiotics
Adenoidectomy
KQ 3: No comparator
KQ
-
effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment
July 19, 2013 - Pharmacokinetic/ Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia … Research Protocol
Archived
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Systematic Review
Archived
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic
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effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
October 12, 2020 - or not or in choice of antibiotic
regimens”? … commenter
from American
College of
Physicians
Throughout • Throughout, we recommend using the
term “antibiotic … treatment” when you are
referring to antibiotics. … E.g., instead of
“There is low SoE that antibiotics for
patients…” replace with “There is low SoE … that antibiotic treatment for patients…”
We agree and have made changes
throughout.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - or non-antibiotic--treatments) on the number and severity of throat
infections, quality … Ingredient Cold, Flu, and Allergy Medications [mh] OR Respiratory
System Agents [mh] OR Anti … -Bacterial Agents [mh] OR antibiotic [tiab] OR Anti-
Allergic Agents [mh]
11304977
3 … Overprescribing and inappropriate
antibiotic selection for children with pharyngitis in the … Antibiotics: Antibiotics approved by the FDA specifically for treating streptococcal tonsillitis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Topical antibiotic- or antiseptic-impregnated dressings for clinically
noninfected chronic venous leg … Topical antibiotic- or antiseptic-impregnated dressings for clinically
noninfected chronic venous leg … Topical Antibiotic or Antiseptic-Impregnated Dressings
For patients with chronic, clinically noninfected … Low-Priority Evidence Gaps
Systemic Antibiotics
Determining the appropriate use of systemic antibiotics … one antibiotic that you believe should
be tested first?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Appropriate antibiotic usage
2. Positive environmental cultures
3. … Antibiotics and hospital-acquired Clostridium difficile-
associated diarrhoea: a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
August 07, 2012 - Antibiotics currently are not commonly used in the United States to treat OME and are not
recommended … for the treatment of OME.6, 10, 20 An upcoming Cochrane Collaboration review on
the use of antibiotics … Oral steroids
alone or in combination with antibiotics had a positive effect on 2-week disease outcomes … Antibiotics for otitis media with effusion in
children (protocol). … Which antibiotic for acute otitis media? Drug Ther Bull. 1974 Jul 5; 12(14):53-4.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
November 16, 2015 - tympanostomy tubes for children with
otitis media, indications for tympanostomy in children, prescription of antibiotics … drops versus systemic antibiotics or watchful
waiting on duration of otorrhea, quality of life, or … prophylaxis
• KQ 5: Ototopical preparations
o Ototopical antibiotics
§ FDA approved (i.e … for recurrent episodes of AOM
o Prophylactic antibiotics
o Adenoidectomy
• KQ 3: No comparator … Antibiotic use
3. Recurrent AOM/otorrhea (KQ 2)
4.