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effectivehealthcare-admin.ahrq.gov/products/tympanostomy-tubes/research-protocol
March 01, 2021 - for tube candidacy. 1 The American Academy of Pediatrics CPG discourages routine use of prophylactic antibiotics … drops versus systemic antibiotics or watchful waiting on duration of otorrhea, quality of life, or need … prophylaxis
KQ 5: Ototopical preparations
Ototopical antibiotics
FDA approved (i.e., … for recurrent episodes of AOM
Prophylactic antibiotics
Adenoidectomy
KQ 3: No comparator … water exposure
Avoidance of higher risk activities
KQ 5:
Watchful waiting
Oral (systemic) antibiotics
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effectivehealthcare-admin.ahrq.gov/products/tonsillectomy/research-protocol
March 01, 2020 - or non-antibiotic--treatments) on the number and severity of throat infections, quality of life, and … mh] OR Multi-Ingredient Cold, Flu, and Allergy Medications [mh] OR Respiratory System Agents [mh] OR Anti-Bacterial … Agents [mh] OR antibiotic [tiab] OR Anti-Allergic Agents [mh]
11304977
3
palatine tonsil[mh … Overprescribing and inappropriate antibiotic selection for children with pharyngitis in the United States … Antibiotics: Antibiotics approved by the FDA specifically for treating streptococcal tonsillitis include
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effectivehealthcare-admin.ahrq.gov/sites/default/files/deliberative-methods-facilitation-slides-text.pdf
January 11, 2017 - o Decisions grounded in personal/societal values
Slide 7
The overuse of antibiotics … patients
o What information might be useful to convey to the public about the risk of
overusing antibiotics … Slide 8
The overuse of antibiotics: deliberative session
• Question: should there be more specific … limits on how doctors use antibiotics?
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effectivehealthcare-admin.ahrq.gov/health-topics/tonsillitis
If the cause is a bacterial infection, such as strep throat, your child will need to take antibiotics … It is important for your child to finish the antibiotics even if he or she feels better. … if he or she
Keeps getting tonsillitis
Has bacterial tonsillitis that does not get better with antibiotics
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - Of note is that recommendations to increase dosing
levels for many antibiotics were included in the … In addition, therapeutic drug monitoring (TDM)
is only performed for a few selected antibiotics in practice … There was a lack of data to support the use of continuous
infusion of betalactam antibiotics compared … Again, readers of such a review are
likely looking for guidance on dosing antibiotics for multi-
drug … resistant organisms, or organisms with high MICs to
traditional antibiotics.
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effectivehealthcare-admin.ahrq.gov/health-topics/acute-bronchitis
January 07, 2013 - Antibiotics won't help if the cause is viral. You may get antibiotics if the cause is bacterial.
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effectivehealthcare-admin.ahrq.gov/products/c-diff-infections/research-protocol
December 01, 2019 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. … Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the
increasing … problem of antibiotic resistance. … Discriminate use of antibiotics for exacerbation of COPD. … leukocytosis,
pyuria), as
described in
guidelines
The comparator is specified as initiation
of antibiotics … as described in
guidelines to clarify the true comparator
for procalcitonin-guided initiation of
antibiotics
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effectivehealthcare-admin.ahrq.gov/sites/default/files/diverticulitis-comments.pdf
October 12, 2020 - or not or in choice of antibiotic
regimens”? … commenter
from American
College of
Physicians
Throughout • Throughout, we recommend using the
term “antibiotic … treatment” when you are
referring to antibiotics. … E.g., instead of
“There is low SoE that antibiotics for
patients…” replace with “There is low SoE … that antibiotic treatment for patients…”
We agree and have made changes
throughout.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - or non-antibiotic--treatments) on the number and severity of throat
infections, quality … Ingredient Cold, Flu, and Allergy Medications [mh] OR Respiratory
System Agents [mh] OR Anti … -Bacterial Agents [mh] OR antibiotic [tiab] OR Anti-
Allergic Agents [mh]
11304977
3 … Overprescribing and inappropriate
antibiotic selection for children with pharyngitis in the … Antibiotics: Antibiotics approved by the FDA specifically for treating streptococcal tonsillitis
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Topical antibiotic- or antiseptic-impregnated dressings for clinically
noninfected chronic venous leg … Topical antibiotic- or antiseptic-impregnated dressings for clinically
noninfected chronic venous leg … Topical Antibiotic or Antiseptic-Impregnated Dressings
For patients with chronic, clinically noninfected … Low-Priority Evidence Gaps
Systemic Antibiotics
Determining the appropriate use of systemic antibiotics … one antibiotic that you believe should
be tested first?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Appropriate antibiotic usage
2. Positive environmental cultures
3. … Antibiotics and hospital-acquired Clostridium difficile-
associated diarrhoea: a systematic review.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
August 07, 2012 - Antibiotics currently are not commonly used in the United States to treat OME and are not
recommended … for the treatment of OME.6, 10, 20 An upcoming Cochrane Collaboration review on
the use of antibiotics … Oral steroids
alone or in combination with antibiotics had a positive effect on 2-week disease outcomes … Antibiotics for otitis media with effusion in
children (protocol). … Which antibiotic for acute otitis media? Drug Ther Bull. 1974 Jul 5; 12(14):53-4.
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effectivehealthcare-admin.ahrq.gov/products/venous-ulcers-treatment/research
December 01, 2019 - Abstract
Objectives
To systematically review whether the use of advanced wound dressings, systemic antibiotics … We found insufficient evidence evaluating the benefits and harms of the routine use of antibiotics.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
November 16, 2015 - tympanostomy tubes for children with
otitis media, indications for tympanostomy in children, prescription of antibiotics … drops versus systemic antibiotics or watchful
waiting on duration of otorrhea, quality of life, or … prophylaxis
• KQ 5: Ototopical preparations
o Ototopical antibiotics
§ FDA approved (i.e … for recurrent episodes of AOM
o Prophylactic antibiotics
o Adenoidectomy
• KQ 3: No comparator … Antibiotic use
3. Recurrent AOM/otorrhea (KQ 2)
4.
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effectivehealthcare-admin.ahrq.gov/health-topics/ear-infections
June 01, 2017 - Severe infections and infections in young babies may require antibiotics. … Requirements: Tympanostomy Tubes
Systematic Review Archived January 27, 2016
Improving Antibiotic … Tubes
Research Protocol Archived May 23, 2014
Interventions to Improve Appropriate Antibiotic
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effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
January 01, 2022 - Antibiotic treatment: For patients with uncomplicated diverticulitis, antibiotic treatment may not affect … symptoms, length of hospital stay, recurrence risk, quality of life, or need for surgery compared to no antibiotic … For patients who do receive antibiotics, the evidence is insufficient to guide choice of antibiotic regimen … For patients with uncomplicated acute diverticulitis, there is low SoE that antibiotic treatment does
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effectivehealthcare-admin.ahrq.gov/products/c-difficile-update/clinician
December 01, 2019 - Lactobacillus probiotics, when used as an adjunct to antibiotic therapy, may prevent the recurrence of … diarrhea (≥3 loose stools in 24 hours) or ileus who have additional risk factors (including use of antibiotics … Antibiotic Stewardship
6
Appropriate prescribing practices were associated with decreased CDI. … The costs of the antibiotics used to treat CDI vary significantly. … What To Discuss With Your Patients and Their Caregivers
The role that use or overuse of antibiotics
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Azithromycin (Zithromax®, Pfizer,
Inc., New York, NY), is a macrolide antibiotic with broad-spectrum … Additionally, investigators noted concern about antibiotic-resistant bacteria in
patients treated with … Some experts
stated risk of hearing loss, cardiac arrhythmias, and antibiotic resistance are factors … that would make
some physicians reluctant to prescribe the antibiotic. … Antibiotic prevention of acute exacerbations of
COPD. N Engl J Med. 2012 Jul 26;367(4):340-7.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/facilitation-webcast-slides.pptx
June 13, 2013 - (next slide)
6
The overuse of antibiotics: focus group
Question: How can doctors better communicate … ; and the educational approach or information that will gain patients’ cooperation in not overusing antibiotics … (next slide)
7
The overuse of antibiotics: deliberative session
Question: should there be more specific … limits on how doctors use antibiotics? … Should there be more specific limits on how doctors use antibiotics?