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digital.ahrq.gov/ahrq-funded-projects/identifying-sepsis-phenotypes-associated-antibiotic-resistant-pathogens-using
August 01, 2024 - Current guidelines recommend the immediate use of broad-spectrum antibiotics for suspected sepsis to … However, this approach often leads to the overuse of these powerful antibiotics, even when they are not … immune to the effects of antibiotics, making infections harder to treat in the future. … better antibiotic use. … Quantify the impact of overly broad vs appropriate vs overly narrow antibiotics on patient outcomes in
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digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/christakis-da-et-al
January 01, 2023 - Christakis DA et al. 2001 "A randomized controlled trial of point-of-care evidence to improve the antibiotic … A randomized controlled trial of point-of-care evidence to improve the antibiotic prescribing practices … To determine whether point-of-care evidence delivery regarding the use and duration of antibiotics for … Proportion of prescriptions for otitis media that were for <10 days and frequency with which antibiotics … When providers selected an antibiotic medication, they were shown a popup screen with a five-line summary
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/evaluation-computer-assisted-0
October 01, 1999 - dosages of antibiotics and the number of antibiotic-related adverse drug events (ADEs) Years of study … Healthcare Utilization: Reduction in mean number of doses, grams of antibiotics, lower mean cost for … the study antibiotics. … Quality of Care and Patient Safety Outcome: 66% reduction in ADEs for patients on study antibiotics … , p<0.001) Changes in healthcare costs: Lower mean cost for study antibiotics($80.62 vs. $92.96, p <
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/improving-empiric-antibiotic
April 25, 1994 - of appropriate empiric antibiotics. … Intervention: Ordering antibiotics suggested by the computerized antibiotic consultant was compared … to antibiotics ordered by physicians. … Evaluation Method: Measures of antibiotics selection and timing, and provider satisfaction. … Quality of Care and Patient Safety Outcome: The antibiotic consultant suggested an antibiotic regimen
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digital.ahrq.gov/health-it-tools-and-resources/workflow-assessment-health-it-toolkit/research/shebl-na-et-al-2007
January 01, 2007 - Shebl NA et al. 2007 "Clinical decision support systems and antibiotic use." … and after' studies published on clinical decision support systems (CDSS) used to support the use of antibiotics … 1970-2006) using the combinations of the following terms: (Decision support systems) or (CDSS) AND (antibiotics … It presents a promising future for optimising antibiotic use. … Objective
"To summarise the relevant literature available regarding the use of CDSS and antibiotics
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/randomized-controlled-trial-0
February 01, 2001 - A randomized controlled trial of point-of-care evidence to improve the antibiotic prescribing practices … prescriptions for otitis media with duration < 10 days, frequency of antibiotic prescriptions for otitis … Intervention: Point-of-care messaging system to pediatric providers regarding antibiotic prescribing … Healthcare Utilization: Greater reduction in the proportion of antibiotics prescribed for > 10 days … and less frequent prescribing of antibiotics for otitis media (intervention vs. control)
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/anesthesia-information-system
October 01, 2006 - system designed to provide physician-specific feedback improves timely administration of prophylactic antibiotics … how an anesthesia clinical information system was used to implement practice guidelines for timely antibiotic … administration and to provide feedback to individual providers to meet the goal of antibiotic administration … an existing perioperative information system to prompt anesthesia providers regarding pre-operative antibiotics … ; provide report cards to providers regarding percent compliance with timely antibiotic administration
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digital.ahrq.gov/principal-investigator/pak-theodore-r
January 01, 2023 - Identifying Sepsis Phenotypes Associated with Antibiotic-Resistant Pathogens Using Large Language Models … outcomes, with the goal of shaping future clinical guidelines that help doctors select the most effective antibiotics … for each patient, reduce unnecessary use of broad-spectrum antibiotics, lower the risks of drug resistance
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/pilot-study-web-based-antibiotic
March 01, 2006 - Pilot study of a web-based antibiotic decision management guide
Authors: Bochicchio, G. … Purpose of Study: To determine the impact of physician use of a PDA loaded with an antibiotics guide … quality Summary: Settings: Trauma center at University of Maryland hospital Intervention: Johns Hopkins Antibiotics … Outcomes were antibiotic decision accuracy as well as 3 and 6 month examination scores on knowledge of … The program has 3 modules: diagnosis, pathogen, and antibiotic.
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digital.ahrq.gov/program/division-research-education-office-extramural-research-education-and-priority-populations
January 01, 2023 - training-grants/index.html
Identifying Sepsis Phenotypes Associated with Antibiotic-Resistant … outcomes, with the goal of shaping future clinical guidelines that help doctors select the most effective antibiotics … for each patient, reduce unnecessary use of broad-spectrum antibiotics, lower the risks of drug resistance
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digital.ahrq.gov/ahrq-funded-projects/improving-guideline-development-and-implementation/citation/improving
January 01, 2023 - Improving diagnostic testing and reducing overuse of antibiotics for children with pharyngitis: a useful … Improving diagnostic testing and reducing overuse of antibiotics for children with pharyngitis: a useful
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/computer-surveillance-hospital
Computer surveillance of hospital-acquired infections and antibiotic use
Authors: Evans RS … Purpose of Study: To improve the identification of hospital-acquired infections and associated antibiotic … microbiology laboratory in order to identify patients 1) with hospital-acquired infections, 2) not receiving antibiotics … During the 2-month study period, the HIT system generated 108 antibiotic-related alerts, of which 40 … Lastly, the computer correctly identified 142 of the 156 patients who were receiving prophylactic antibiotics
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/electronic-chart-prompt-decrease
March 01, 2005 - An electronic chart prompt to decrease proprietary antibiotic prescription to self-pay patients … Intervention: Compare rates of prescribing for proprietary antibiotics before and after introduction … Description: Electronic prescription writing system which displays a prompt when any of 74 antibiotics … , with bold red letters reminding the provider to check the patient insurance status before writing antibiotic
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digital.ahrq.gov/sites/default/files/docs/health-care-delivery-children-slides-063016.pdf
June 30, 2016 - Use in Viral Illness
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Disparities in Care
• Outcome:
► Antibiotic (oral or IV/IM) administration … by Race/Ethnicity
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Antibiotics by Race/Ethnicity
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Antibiotics by Race/Ethnicity
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Antibiotics … by Race/Ethnicity
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Antibiotics by Race/Ethnicity
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Antibiotics by Race/Ethnicity
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Antibiotics … Antibiotics by Race/Ethnicity
Antibiotics by Race/Ethnicity
Antibiotics by Race/Ethnicity
Antibiotics … by Race/Ethnicity
Antibiotics by Race/Ethnicity
Antibiotics by Race/Ethnicity
Antibiotics by Race
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digital.ahrq.gov/technology/generative-artificial-intelligence
January 01, 2023 - Artificial Intelligence
Identifying Sepsis Phenotypes Associated with Antibiotic-Resistant … outcomes, with the goal of shaping future clinical guidelines that help doctors select the most effective antibiotics … for each patient, reduce unnecessary use of broad-spectrum antibiotics, lower the risks of drug resistance
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/improved-perioperative
July 01, 1989 - Improved perioperative antibiotic use and reduced surgical wound infections through use of computer decision … Purpose of Study: Determine whether computer-generated reminders of perioperative antibiotic use could … Evaluation Method: Measures of antibiotic use, timing of antibiotic use, and number of postoperative … Description: A computer system with guidelines and an application to monitor perioperative antibiotic … Among these patients, antibiotics were given within two hours before the surgical incision in 638 (40%
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/computer-assisted-management
January 22, 1998 - A computer-assisted management program for antibiotics and other antiinfective agents
Authors … Purpose of Study: Improve the use of antibiotics and other anti-infective agents Years of study: 1992 … Compared to the pre-intervention control period there was a slight increase in the overall use of antibiotics
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digital.ahrq.gov/health-it-tools-and-resources/health-it-costs-and-benefits-database/handheld-computer-based-decision
Handheld computer-based decision support reduces patient length of stay and antibiotic prescribing in … Purpose of Study: To assess the effect of a handheld computerized decision support system on antibiotic … guidelines, unit-specific antibiotic susceptibility data for common bacterial pathogens, and a clinical … overuse is linked to the development and spread of microbial antibiotic resistance in ICUs Healthcare … Use of antibiotics decreased from 1,767 DDD (defined daily doses) to 1,458 DDD per 1,000 patient-days
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digital.ahrq.gov/organization/massachusetts-general-hospital
January 01, 2023 - Massachusetts General Hospital
Identifying Sepsis Phenotypes Associated with Antibiotic-Resistant … outcomes, with the goal of shaping future clinical guidelines that help doctors select the most effective antibiotics … for each patient, reduce unnecessary use of broad-spectrum antibiotics, lower the risks of drug resistance
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digital.ahrq.gov/sites/default/files/docs/publication/Parisetal_HFES2008.pdf
January 01, 2008 - understanding the role of
communication between various disciplines in ensuring the timely administration of antibiotics … the life-saving interventions in the ICU include the
administration of numerous medications such as antibiotics … As a result, the guidelines for management of
sepsis state that antibiotics should be administered … In this hospital, first-dose antibiotics are to be treated
differently than other medications: they … order for the pharmacist to determine the
appropriate dose of the medication, for example, for
antibiotics