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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/long-term-care/one-pager-side-effects.pdf
June 01, 2021 - Antibiotic Side Effects
Risk of antibiotic side effects and adverse reactions
• Antibiotic use is … (5–25%)
• Antibiotics can lead to nephrotoxicity (damage to kidneys), neurotoxicity (damage to central … and/or
peripheral nervous system), skin reactions such as rashes, or yeast infections
• Antibiotics … Meta-
analysis of antibiotics and the risk of community-
associated Clostridium difficile infection. … Community-associated Clostridium difficile
infection and antibiotics: a meta-analysis.
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www.ahrq.gov/sites/default/files/wysiwyg/professionals/quality-patient-safety/hais/tools/surgery/tools/surgical-complication-prevention/antibiotic_audit.docx
December 01, 2017 - This tool will help your safety program team understand how appropriately you are using prophylactic antibiotics … Antibiotic infusion stop time
Antibiotic 1
Name:
Dose:
Time (1):
Time (2):
Time (3):
Antibiotic … Question 15: Assess if the antibiotics clindamycin or cefotetan were redosed during the case. … If the antibiotics were redosed, determine and document if the difference in time between the first antibiotic … Antibiotic infusion stop time
Antibiotic 1
Name:
Dose:
Time (1):
Time (2):
Time (3):
Antibiotic
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www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/009-antibiotic-stewardship-guide.docx
October 01, 2024 - Antibiotic stewardship aims to optimize the use of antibiotics by ensuring antibiotics are prescribed … Slide 4
Some Facts About Antibiotic Use
SAY:
Antibiotics have revolutionized modern medicine and saved … antibiotic regimens, use of antibiotics in patients who do not have signs or symptoms of infection, … antibiotic use is to decide what antibiotics or syndromes you want to target on the unit. … On the front, the prescriber is asked to provide an indication for antibiotics, assess whether antibiotic
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/improve/team-antibiotic-review-form.docx
November 01, 2019 - AHRQ Safety Program for Improving Antibiotic Use
Team Antibiotic Review Form
*Questions 1–6 should … Question 2: Record antibiotic regimen and indication below:
Antibiotic:
Indication:
Antibiotic … :
Indication:
Antibiotic:
Indication:
Antibiotic:
Indication:
Moment ONE
Question … ☐ Yes
☐ No
2
Team Antibiotic Review Form
AHRQ Safety Program for Improving Antibiotic Use – … Moment THREE
Question 7: Are antibiotics still needed?
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www.ahrq.gov/topics/antibiotics.html
Antibiotics
Antibiotics are powerful medicines that fight bacterial infections. … Antibiotic resistance is becoming a national threat. … AHRQ's efforts for combating antibiotic-resistanct bacteria focus on promoting appropriate antibiotic … Antibiotic Stewardship Toolkits MRSA Prevention Toolkits
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/long-term-care/antibiotic-targets-facilitator-guide.docx
June 01, 2021 - AHRQ Safety Program for Improving Antibiotic Use
1
Identifying Targets To Improve Antibiotic Use
Long-Term … · Prescribing antibiotics for too long
· Forgetting to stop antibiotics when they are not needed
· Accidentally … It’s been 2–3 days since we started antibiotics. … Can we stop antibiotics? Can we narrow therapy? … She met criteria for empiric antibiotics.
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/long-term-care/learning-from-antibiotic-adverse.docx
June 01, 2021 - AHRQ Safety Program for Improving Antibiotic Use
Learning From Antibiotic-Associated Adverse Events
An … Negative Factor
Positive Factor
Patient
Factors
Example: Family preferred antibiotics. … X
Team
Factors
Example: Team discussion about need to start antibiotics occurred … Have we collected appropriate cultures and diagnostic tests before starting antibiotics? … Can we stop antibiotics? Can we narrow therapy?
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/improve/antibiotic-time-out-tool.docx
November 01, 2019 - Antibiotic 1:
Treatment day #:
Antibiotic 2:
Treatment day #:
Antibiotic 3:
Treatment … day #:
Check the patient’s indication(s) for continuing antibiotics below:
Antibiotic Time Out … for any of the following conditions even though antibiotics are NOT typically recommended? … Can any of the antibiotics be discontinued? … ☐ Yes
☐ No
Are the antibiotics selected consistent with local guidelines?
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/improve/team-antibiotic-review-form-completion-guide.pdf
November 01, 2019 - Completion Guide_Team Antibiotic Review Form
AHRQ Safety Program for Improving Antibiotic Use … Day of antibiotic therapy:
For the antibiotic or antibiotic regimen you are evaluating, day 1 is the … Antibiotic regimen and indication:
Include all antibiotics that the patient is receiving. … • If the patient has a reported antibiotic allergy but the specific antibiotic was not recorded or … Day of antibiotic therapy:
Question 2. Antibiotic regimen and indication:
Question 3.
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/long-term-care/antibiotic-patient-safety-facilitator-guide.docx
June 01, 2021 - AHRQ Safety Program for Improving Antibiotic Use
1
Improving Antibiotic Use Is a Patient Safety Issue … Slide 3
Antibiotic Development Is on the Decline
SAY:
Antibiotics are a precious resource. … For all of us, using antibiotics judiciously is critical to making sure antibiotics continue to remain … Slide 5
Antibiotics Alter the Bacteria in the Gut
SAY:
When people take antibiotics to treat an … Slide 6
Antibiotics & Clostridioides difficile
SAY:
After taking an antibiotic, people are at greater
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/long-term-care/program-dev-slides.pptx
June 01, 2021 - To use antibiotics only when necessary, thereby protecting residents from unnecessary antibiotic exposure … No followup on the resident to note her response to antibiotics. … No followup on the resident to note her response to antibiotics. … No followup on the resident to note her response to antibiotics. … Cost of antibiotics
Use of guideline-concordant antibiotics
Clostridioides difficile infection rates
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/safety/antibiotic-use-commitment-poster.docx
November 01, 2019 - No. 17(20)-0028-EF
November 2019
Our institution is committed to prescribing the most appropriate antibiotics … when they are needed and to not prescribing antibiotics when they are not needed. … Please ask a member of your medical team if you have any questions about antibiotics.
Thank you! … Antibiotics are lifesaving drugs but can have harmful side effects. … the individuals you believe are important to indicate your institution’s commitment to prescribing antibiotics
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/ambulatory-care/antibiotic-stewardship.pdf
September 01, 2022 - of antibiotics. … • The Antibiotics: When Are They Needed? … https://www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/ambulatory-care/antibiotics-brochure-english.docx … https://www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/ambulatory-care/antibiotics-brochure-spanish.docx … use and enhance the safety
of patients receiving antibiotics.
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/safety/identifying-antibiotic-adverse-events-form.docx
November 01, 2019 - AHRQ Safety Program for Improving Antibiotic Use
Identifying Antibiotic-Associated … Adverse Events Form
PURPOSE OF THIS FORM:
To discuss issues that may result in unnecessary antibiotic … administration or antibiotic-associated adverse events that could negatively impact patient safety. … next patient in your unit or clinical area will be harmed by an event related to administration of antibiotics … or by receiving unnecessary antibiotics.
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psnet.ahrq.gov/web-mm/inappropriate-antibiotic-use
September 22, 2010 - Inappropriate Antibiotic Use. PSNet [internet]. … infectious cause not covered by antibiotics. … Many physicians find it hard to limit antibiotic use when they think that broad-spectrum antibiotic coverage … How can overuse of antibiotics be prevented? … Strategies to improve antibiotic stewardship and reduce antibiotic resistance have recently been summarized
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www.ahrq.gov/sites/default/files/wysiwyg/professionals/quality-patient-safety/quality-resources/tools/cauti-ltc/modules/implementation/educational-bundles/urine-culturing/antibiotic-stewardship/abx-stewardship-part2.pptx
March 01, 2017 - Every course of antibiotics carries these risks—and nursing home residents get a lot of antibiotics each … We are learning when to give antibiotics and when to withhold antibiotics.
6
Antibiotic Use in LTC … use of antibiotics.
7
Fighting Back Against Antibiotic Resistance1
Infection prevention IS antibiotic … Improving antibiotic prescribing
Bacteria are constantly evolving, requiring the need for new antibiotics … become resistant to antibiotics.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - Current antibiotic dosing strategies also do not directly
consider the variety of antibiotic-resistance … Given the PK/PD properties of antibiotics, clinicians can
optimize the PD effects of antibiotics by … Among them are improving appropriate use of antibiotics
by promoting antibiotic use only when indicated … antibiotic doses. … concepts such as using extended or prolonged infusions
of time-dependent antibiotics.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - Antibiotic PD relates PK parameters to the
ability of an antibiotic to kill or inhibit growth of bacterial … , clinicians can optimize the PD effects of
antibiotics by altering the dosing methods for the antibiotic … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … ] OR "Anti-Bacterial Agents"[mesh])
Limits Humans
English language
Adults 19+ years or Adults 18
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/safety/learning-antibiotic-adverse-events-form.docx
November 01, 2019 - AHRQ Safety Program for Improving Antibiotic Use
Learning From Antibiotic-Associated Adverse … Events
An antibiotic-related adverse event is any event or situation involving the prescription or administration … of antibiotics that you would not want to happen again because it either caused your patient harm or … Identify the antibiotic-associated adverse event.
2. … From
Antibiotic-Associated
Adverse Events Form
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www.ahrq.gov/sites/default/files/wysiwyg/antibiotic-use/safety/patient-safety-slides.pptx
November 01, 2019 - of antibiotics is not entirely benign! … one antibiotic during their hospital stay.1
Approximately 30-50% of antibiotics hospitalized patients … Use – Patient Safety Issue
AHRQ Safety Program for Improving Antibiotic Use – Acute Care
6
Antibiotics … Care
7
Antibiotics & Clostridiodes difficile
Antibiotics can increase the risk of Clostridiodes difficile … The Infectious Diseases Society of America’s 10 x ’20 Initiative (Ten new systemic antibacterial agents