-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0543_05-24-2013.pdf
January 01, 2013 - management, for
reducing inappropriate antibiotic use for acute cough illness (ACI). … Existing clinical guidelines
recommend against routine antibiotic use for ACI in otherwise healthy adults … The conclusions in the most recent clinical trials
note that a decrease in antibiotic use was associated … with delayed antibiotic strategies, patient
education, and physician education and are consistent with … While it is clear the antibiotics are not useful, a new systematic review on this topic can be used
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-2ndplace-paws.pdf
January 26, 2013 - P A W S, Prescription for Antibiotics or Wait and See: Ear Infections: Are Antibiotics the Right Choice … P A W S
Prescription for
Antibiotics or
Wait and See
Ear Infections
Are Antibiotics the Right … Not all ear infections require imme-
diate treatment with antibiotics. … Antibiotics that are taken when they
are not needed can be harmful. … Af-
ter each course of antibiotics, re-
sistant bacteria may develop.
-
effectivehealthcare.ahrq.gov/system/files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - o Antibiotic treatment: For patients with uncomplicated diverticulitis, antibiotic
treatment may not … For patients who do receive antibiotics, the evidence is insufficient to
guide choice of antibiotic … imaging; (2) the effectiveness and
harms of hospitalization for acute uncomplicated diverticulitis, antibiotics … Antibiotic treatment of acute diverticulitis: With low SoE, studies did not find that
antibiotic treatment … For patients who
do receive antibiotics, the evidence is insufficient to guide choice of antibiotic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - o Antibiotic treatment: For patients with uncomplicated diverticulitis, antibiotic
treatment may not … For patients who do receive antibiotics, the evidence is insufficient to
guide choice of antibiotic … imaging; (2) the effectiveness and
harms of hospitalization for acute uncomplicated diverticulitis, antibiotics … Antibiotic treatment of acute diverticulitis: With low SoE, studies did not find that
antibiotic treatment … For patients who
do receive antibiotics, the evidence is insufficient to guide choice of antibiotic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer78_procalcitonin_disposition_20121210.pdf
October 05, 2012 - on antibiotics per total patient-days for an entire group as a
rate. … For the use of
PCT to reduce initiation or continuation of antibiotics for
acute respiratory tract … The ES only discussed
antibiotics since this was the major theme of the entire systematic
review. … Also, discontinuation of antibiotics or duration of
therapy are intermediate outcomes, and this report … The overuse of antibiotics is not taken into account.
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/management-acute-diverticulitis
June 27, 2018 - Question 1: What are the effectiveness/harms and comparative effectiveness/harms of oral or parenteral antibiotics … for the treatment of diverticulitis compared to each other and compared to treatment without antibiotics … Do the effectiveness/harms vary by route of administration of antibiotic, type of antibiotic, duration … of course of antibiotic? … With the increasing use of oral antibiotics with high bioavailability, parenteral antibiotics given as
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-221-copd-evidence-summary.pdf
October 01, 2019 - Key Messages
• Antibiotic therapy increases the clinical cure rate and
reduces the clinical failure … Systemic Antibiotics Versus Placebo
or Management Without Systemic
Antibiotics
Antibiotics increased … dosages of the
same antibiotic was insufficient for mortality,
clinical cure and clinical failure. … Antibiotic therapy in exacerbations of chronic
obstructive pulmonary disease. … Procalcitonin to guide antibiotic
administration in COPD exacerbations: a meta-
analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - Key Messages
• Antibiotic therapy increases the clinical cure rate and
reduces the clinical failure … Systemic Antibiotics Versus Placebo
or Management Without Systemic
Antibiotics
Antibiotics increased … dosages of the
same antibiotic was insufficient for mortality,
clinical cure and clinical failure. … Antibiotic therapy in exacerbations of chronic
obstructive pulmonary disease. … Procalcitonin to guide antibiotic
administration in COPD exacerbations: a meta-
analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - 1.2 What is the incremental impact of various strategies to reduce
antibiotic usage, such as antibiotic … 6 What is the incremental impact of various strategies to reduce antibiotic usage, such as antibiotic … 1.2 What is the incremental impact of various strategies to reduce
antibiotic usage, such as antibiotic … Duration of treatment with concomitant antibiotics
11. … What is the incremental impact of various strategies to reduce antibiotic usage, such as antibiotic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - of antibiotics or
pain related to ear drops. … oral antibiotics and watchful waiting or placebo. … , topical antibiotic-glucocorticoid drops are superior to oral antibiotics and there is a
suggestion … drops vs. systemic antibiotics or watchful waiting
Topical antibiotic-glucocorticoid drops are superior … to oral
antibiotics in achieving clinical cure
Topical antibiotic drops are superior to oral antibiotics
-
effectivehealthcare.ahrq.gov/products/copd/research
October 11, 2019 - Key Messages
Antibiotic therapy increases the clinical cure rate and reduces the clinical failure rate … Antibiotics and corticosteroids are not associated with increase in serious adverse events. … Antibiotic therapy increases the clinical cure rate and reduces the clinical failure rate regardless … There is insufficient evidence to support a particular antibiotic regimen. … Systemic antibiotics and corticosteroids are associated with improved outcomes in mild and moderate to
-
effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
August 13, 2018 - Do the effectiveness/harms vary by route of administration of antibiotic, type of antibiotic,
duration … of course of antibiotic? … ,
clear liquid diet
only, antibiotics by
other route of
administration,
type of antibiotic,
duration … exp Anti-Bacterial Agents/ or ((oral* or parenteral*) adj3 (antibiotic* or
antibacterial* or anti-bacterial … cond=diverticulitis&term=&cntry=&state=&city=&dist=
KQ 1 (Antibiotics)
• Antibiotics vs. resection
-
effectivehealthcare.ahrq.gov/products/procalcitonin/research-protocol
April 26, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the increasing … problem of antibiotic resistance. … Intermediate outcomes—such as antibiotic exposure, duration of antibiotic therapy, length of stay, and … Discriminate use of antibiotics for exacerbation of COPD. Curr Opin Pulm Med 2009;15:126-32. … leukocytosis, pyuria), as described in guidelines
The comparator is specified as
initiation of antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0768-141211.pdf
October 23, 2014 - least 3
episodes per year for 3 years)
Intervention(s): Tonsillectomy
Comparator(s): Prophylactic antibiotic … PICO
Population(s): Children, ages 1 to 18, who undergo tonsillectomy
Intervention(s): Perioperative antibiotic … Should clinicians administer or prescribe perioperative antibiotics to children
undergoing tonsillectomy … effectiveness of tonsillectomy in SDB and
the comparative effectiveness of prescribing perioperative antibiotics … some reduction in morbidities associated with tonsillectomy through the use of
perioperative topical antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
April 11, 2018 - ,
where safely possible, to reduce potential harms including development of antibiotic
resistance, … Antibiotic therapy in exacerbations of chronic
obstructive pulmonary disease. … Antibiotic treatment in exacerbations of chronic
obstructive pulmonary disease: Recent trial
results … 2 Receptor Agonists/ or exp
Cholinergic Antagonists/ or exp Phosphodiesterase 4 Inhibitors/ or exp Antibiotic … Prophylaxis/ or exp Anti-Bacterial Agents/ or exp antibiotic agent/ or exp
Benzodiazepines/ or exp
-
effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - (Strong
recommendation, high-quality evidence)
• In patients in whom oral antibiotics cannot reach … therapy directed against the underlying
infection or who require retreatment with antibiotics shortly … • A prolonged course of oral antibiotics is acceptable therapy for recurrent or resistant disease … repeated antibiotic treatment, fecal transplantation in
combination with oral antibiotic treatment is … Antibiotics remain the mainstay of
treatment recommendations for mild-moderate CDI, with consideration
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - Antibiotics that disturb colon flora enough to
allow CDI to develop must get into the colon, and they … the likelihood that the
recommended antibiotics might induce CDI. … While several studies found increased risk with specific
antibiotics or antibiotic classes, the antibiotics … Identifying
new antibiotics may be one approach. … Impact of a
reduction in the use of high-risk antibiotics on the
course of an epidemic of Clostridium
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the
increasing … problem of antibiotic resistance. … Discriminate use of antibiotics for exacerbation of COPD. … leukocytosis,
pyuria), as
described in
guidelines
The comparator is specified as initiation
of antibiotics … as described in
guidelines to clarify the true comparator
for procalcitonin-guided initiation of
antibiotics
-
effectivehealthcare.ahrq.gov/products/diverticulitis/protocol
September 12, 2019 - Initially reserved for the sickest, highest-risk surgical patients, drainage and antibiotic treatment … Do the (comparative) effects and harms vary by route of administration of antibiotics, type of antibiotic … , and duration of course of antibiotics? … versus No antibiotics or versus Alternative antibiotic regimen (for any patient)
Any class, route, … Prospective randomized trial comparing short-term antibiotic therapy versus standard therapy for acute
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - Initially reserved for the sickest, highest-risk surgical patients,
drainage and antibiotic treatment … • Do the (comparative) effects and harms vary by route of administration of antibiotics,
type of antibiotic … , and duration of course of antibiotics? … versus No antibiotics or versus Alternative antibiotic regimen (for any
patient)
o Any class, route … to each
other and to placebo (or no antibiotics).