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effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - 1.2 What is the incremental impact of various strategies to reduce
antibiotic usage, such as antibiotic … 6 What is the incremental impact of various strategies to reduce antibiotic usage, such as antibiotic … 1.2 What is the incremental impact of various strategies to reduce
antibiotic usage, such as antibiotic … Duration of treatment with concomitant antibiotics
11. … What is the incremental impact of various strategies to reduce antibiotic usage, such as antibiotic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - Of note is that recommendations to increase dosing
levels for many antibiotics were included in the … In addition, therapeutic drug monitoring (TDM)
is only performed for a few selected antibiotics in practice … There was a lack of data to support the use of continuous
infusion of betalactam antibiotics compared … Again, readers of such a review are
likely looking for guidance on dosing antibiotics for multi-
drug … resistant organisms, or organisms with high MICs to
traditional antibiotics.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - of antibiotics or
pain related to ear drops. … oral antibiotics and watchful waiting or placebo. … , topical antibiotic-glucocorticoid drops are superior to oral antibiotics and there is a
suggestion … drops vs. systemic antibiotics or watchful waiting
Topical antibiotic-glucocorticoid drops are superior … to oral
antibiotics in achieving clinical cure
Topical antibiotic drops are superior to oral antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-3rdplace_tympanic.pdf
May 29, 2025 - United States, viral and bacterial ear infections are the most common childhood illnesses treated with
antibiotics … Ceftriaxone, Cefdinir, Cefixime) (9)
Potential negative outcomes of antibiotic use:
1. … Antibiotic resistance
2. Allergic reactions
3. … Fluoroquinolone antibiotics are preferred due to their lack of ototoxicity (7). … If the infection appears to be more
than just localized then oral and sometimes even parenteral antibiotics
-
effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
August 13, 2018 - Do the effectiveness/harms vary by route of administration of antibiotic, type of antibiotic,
duration … of course of antibiotic? … ,
clear liquid diet
only, antibiotics by
other route of
administration,
type of antibiotic,
duration … exp Anti-Bacterial Agents/ or ((oral* or parenteral*) adj3 (antibiotic* or
antibacterial* or anti-bacterial … cond=diverticulitis&term=&cntry=&state=&city=&dist=
KQ 1 (Antibiotics)
• Antibiotics vs. resection
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - Key Messages
• Antibiotic therapy increases the clinical cure rate and
reduces the clinical failure … Systemic Antibiotics Versus Placebo
or Management Without Systemic
Antibiotics
Antibiotics increased … dosages of the
same antibiotic was insufficient for mortality,
clinical cure and clinical failure. … Antibiotic therapy in exacerbations of chronic
obstructive pulmonary disease. … Procalcitonin to guide antibiotic
administration in COPD exacerbations: a meta-
analysis.
-
effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/research
-
effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - (Strong
recommendation, high-quality evidence)
• In patients in whom oral antibiotics cannot reach … therapy directed against the underlying
infection or who require retreatment with antibiotics shortly … • A prolonged course of oral antibiotics is acceptable therapy for recurrent or resistant disease … repeated antibiotic treatment, fecal transplantation in
combination with oral antibiotic treatment is … Antibiotics remain the mainstay of
treatment recommendations for mild-moderate CDI, with consideration
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - Antibiotics that disturb colon flora enough to
allow CDI to develop must get into the colon, and they … the likelihood that the
recommended antibiotics might induce CDI. … While several studies found increased risk with specific
antibiotics or antibiotic classes, the antibiotics … Identifying
new antibiotics may be one approach. … Impact of a
reduction in the use of high-risk antibiotics on the
course of an epidemic of Clostridium
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
April 11, 2018 - ,
where safely possible, to reduce potential harms including development of antibiotic
resistance, … Antibiotic therapy in exacerbations of chronic
obstructive pulmonary disease. … Antibiotic treatment in exacerbations of chronic
obstructive pulmonary disease: Recent trial
results … 2 Receptor Agonists/ or exp
Cholinergic Antagonists/ or exp Phosphodiesterase 4 Inhibitors/ or exp Antibiotic … Prophylaxis/ or exp Anti-Bacterial Agents/ or exp antibiotic agent/ or exp
Benzodiazepines/ or exp
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Conversely, overuse and misuse of antibiotics can result in adverse events and add to the
increasing … problem of antibiotic resistance. … Discriminate use of antibiotics for exacerbation of COPD. … leukocytosis,
pyuria), as
described in
guidelines
The comparator is specified as initiation
of antibiotics … as described in
guidelines to clarify the true comparator
for procalcitonin-guided initiation of
antibiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0768-141211.pdf
October 23, 2014 - least 3
episodes per year for 3 years)
Intervention(s): Tonsillectomy
Comparator(s): Prophylactic antibiotic … PICO
Population(s): Children, ages 1 to 18, who undergo tonsillectomy
Intervention(s): Perioperative antibiotic … Should clinicians administer or prescribe perioperative antibiotics to children
undergoing tonsillectomy … effectiveness of tonsillectomy in SDB and
the comparative effectiveness of prescribing perioperative antibiotics … some reduction in morbidities associated with tonsillectomy through the use of
perioperative topical antibiotics
-
effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/clinician
-
effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/ebc-challenge-1stplace-qrmedica.pdf
January 01, 2013 - AOM is the most common childhood infection for
which antibiotics are prescribed in the United
States. … Antibiotic Options
Amoxicillin
Ampicillin
Cefdinir
Ceftriaxone
Azithromycin … Information on Antibiotic Use
There are a few options to try before an antibiotic; warm compresses, … Amoxicillin is still the safest, most least expensive antibiotic for patients without a penicillin allergy … Some liquid antibiotics, like Amoxicillin, need to be kept in the refrigerator.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Appropriate antibiotic usage
2. Positive environmental cultures
3. … Antibiotics and hospital-acquired Clostridium difficile-
associated diarrhoea: a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-prepub-final-research-appendix-c.xlsx
January 01, 2024 - constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … planned influenza vaccination or vaccination during the previous 12 mo, prebiotics or probiotics, or antibiotic … RCT cross-over < 1992 No industry funding NR Community Healthy smoking, antibiotic use within 6 mo 3 … home), **90 d before the study for antibiotic use and 14 d before the study for the (pro-, prebiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-final-appendix-c.xlsx
January 01, 2024 - constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … planned influenza vaccination or vaccination during the previous 12 mo, prebiotics or probiotics, or antibiotic … RCT cross-over < 1992 No industry funding NR Community Healthy smoking, antibiotic use within 6 mo 3 … home), **90 d before the study for antibiotic use and 14 d before the study for the (pro-, prebiotics
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - Initially reserved for the sickest, highest-risk surgical patients,
drainage and antibiotic treatment … • Do the (comparative) effects and harms vary by route of administration of antibiotics,
type of antibiotic … , and duration of course of antibiotics? … versus No antibiotics or versus Alternative antibiotic regimen (for any
patient)
o Any class, route … to each
other and to placebo (or no antibiotics).
-
effectivehealthcare.ahrq.gov/products/procalcitonin-future/research