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Showing results for "antibiotic".

1. Pneumonia-Antibiotic-Treatment Executive (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
   November 01, 2014 - Current antibiotic dosing strategies also do not directly consider the variety of antibiotic-resistance … Given the PK/PD properties of antibiotics, clinicians can optimize the PD effects of antibiotics by … Among them are improving appropriate use of antibiotics by promoting antibiotic use only when indicated … antibiotic doses. … concepts such as using extended or prolonged infusions of time-dependent antibiotics.

2. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
   July 19, 2013 - Antibiotic PD relates PK parameters to the ability of an antibiotic to kill or inhibit growth of bacterial … , clinicians can optimize the PD effects of antibiotics by altering the dosing methods for the antibiotic … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … ] OR "Anti-Bacterial Agents"[mesh]) Limits Humans English language Adults 19+ years or Adults 18

3. Antibiotic Resistance | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/antibiotic-resistance/

4. Antibiotics-Respiratory-Infection Clinician (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
   March 01, 2016 - A key factor for the increased rate of antibiotic resistance is high outpatient consumption of antibiotics … Antibiotics are frequently inappropriately used for uncomplicated acute RTIs. … ahrq.gov/antibiotics-RTI. … Available at www.effectivehealthcare.ahrq.gov/antibiotics-RTI. … http://www.effectivehealthcare.ahrq.gov/antibiotics-RTI http://www.effectivehealthcare.ahrq.gov/antibiotics-RTI

5. Antibiotics-Respiratory-Infection Executive (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
   January 01, 2016 - With antibiotic use, however, some bacteria can adapt, which can result in the development of antibiotic … of new antibiotics, a key factor is high outpatient consumption of antibiotics.1-3 In response to … Reduced overall prescribing or use of antibiotics for acute RTIs. … antibiotic prescribing, overall prescribing, or antibiotic resistance (Key Questions 1 and 2), with … Data were not available on appropriate antibiotic prescribing or on antibiotic resistance.

6. Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Nosocomial Pneumonia | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol
   July 19, 2013 - Antibiotic PD relates PK parameters to the ability of an antibiotic to kill or inhibit growth of bacterial … Concentration-dependent antibiotic: peak concentration to MIC ratio (C max /MIC) Time-dependent antibiotic … , clinicians can optimize the PD effects of antibiotics by altering the dosing methods for the antibiotic … Rates of antibiotic-related adverse events? … ] OR "Anti-Bacterial Agents"[mesh]) Limits Humans English language Adults 19+ years or Adults

7. Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment/research
   November 24, 2014 - Apr. 16, 2015 Disposition of Comments Report Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … pharmacokinetic/pharmacodynamic (PK/PD) measures or strategies to dose and monitor intravenous (IV) antibiotics … One trial (rated high risk of bias) used PK/PD measures to study the impact of different antibiotic dosing … Evidence is also insufficient to draw conclusions about the effect of continuous infusions of beta-lactam antibiotics … Clinical response, duration of mechanical ventilation, superinfection, rates of antibiotic-related adverse

8. antibiotics-respiratory-infection-protocol-140922 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
   September 22, 2014 - antibiotics for acute RTI. … antibiotics!for!RTI! ! Improved!clinician! knowledge!regarding!use! of!antibiotics!for!RTI! ! … antibiotics! KQ#1:# ! Improved!appropriate! prescription!of!antibiotics! ! Improved!appropriate! … antibiotics! KQ#2:! ! Antibiotic!resistance! ! Medical!complications!)e.g.! Mortality,!Adverse! … Respiratory tract Infections- Antibiotic Prescribing: Prescribing of antibiotics for self-limiting respiratory

9. Interventions To Improve Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/clinician
   April 06, 2016 - A key factor for the increased rate of antibiotic resistance is high outpatient consumption of antibiotics … Antibiotics are frequently inappropriately used for uncomplicated acute RTIs. … Deciding whether to prescribe antibiotics for acute RTIs is a complex process. … The factors associated with overuse of antibiotics for uncomplicated acute RTIs are numerous and diverse … Clinical Interventions (Delayed Versus Immediate Prescribing) Delayed prescribing of antibiotics (see

10. Antibiotics | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/antibiotics/

11. Pharmacokinetic/ Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment
    July 19, 2013 - Pharmacokinetic/ Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia … Research Protocol Archived Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Systematic Review Archived Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic

12. Procalcitonin-Guided Antibiotic Therapy | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/procalcitonin/research
    October 05, 2012 - Outcomes were antibiotic use, mortality, morbidity, and adverse drug events of antibiotic therapy. … Procalcitonin guidance reduces antibiotic use when used to discontinue antibiotics in adult ICU patients … Conclusions Procalcitonin guidance reduces antibiotic use when used to discontinue antibiotics in adult … ICU patients and to initiate or discontinue antibiotics in patients with respiratory tract infections … antibiotic resistance and for adverse events of antibiotic therapy.

13. Procalcitonin Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
    October 01, 2012 - Early initiation of appropriate antibiotics and goal-directed therapies reduces mortality. … Conversely, overuse and misuse of antibiotics, including continuing antibiotics longer than necessary … In view of the present emphasis on the overuse of antibiotics, other interventions to reduce antibiotic … ’s total exposure to all antibiotics and is conventionally reported as mean days per 1,000 days of … to all antibiotics per 1,000 days of followup. 2.

14. Disposition of Comments for CER 163 Appropriate Antibiotics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
    January 27, 2016 - and that antibiotics could be reduced overall. … message about antibiotics to clinicians (“don’t prescribe antibiotics, but you should give patients … Changed to “overuse of antibiotics” 29. … use and antibiotic prescribing. … Peer Reviewer #17 (TEP Reviewer) General Healthcare delivery, access to antibiotics, antibiotic

15. Improving Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection
    May 23, 2014 - Improving Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections Timeline … May 23, 2014 Research Protocol Archived Interventions to Improve Appropriate Antibiotic … Infections January 27, 2016 Systematic Review Archived Improving Antibiotic … April 06, 2016 Clinician Summary Archived Interventions To Improve Antibiotic

16. FRN 29: Future Research Needs on Procalcitonin-Guided Antibiotic Therapy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
    August 01, 2014 - Conversely, overuse and misuse of antibiotics, including continuing antibiotics longer than necessary … Conversely, overuse and misuse of antibiotics, including continuing antibiotics longer than necessary … to discontinue antibiotics in adult ICU patients and to initiate or discontinue antibiotics in patients … Consistent use of measures of total antibiotic exposure (e.g. mean days total exposure to all antibiotics … Vulnerable to antibiotic resistance and adverse effects of antibiotics.

17. Treating and Preventing C. difficile Infections (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_consumer.pdf
    May 01, 2017 - Antibiotics If your CDI happened after you took an antibiotic, your health care professional may have … you stop taking the antibiotic. … The antibiotic your doctor recommends may depend on the availability and cost of the antibiotic, what … Take all antibiotics exactly as instructed. … the antibiotic?

18. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
    November 24, 2014 - Of note is that recommendations to increase dosing levels for many antibiotics were included in the … In addition, therapeutic drug monitoring (TDM) is only performed for a few selected antibiotics in practice … There was a lack of data to support the use of continuous infusion of betalactam antibiotics compared … Again, readers of such a review are likely looking for guidance on dosing antibiotics for multi- drug … resistant organisms, or organisms with high MICs to traditional antibiotics.

19. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
    November 03, 2014 - uncertainty regarding indications for Summary: tympanostomy in children as well as the prescription of antibiotics … drops and/or systemic antibiotics for children with tympanostomy tube otorrhea (TTO)? … drops or systemic antibiotic administration Comparator(s): Systemic antibiotic administration or topical … Should clinicians prescribe topical antibiotic eardrops and/or antibiotics for children with uncomplicated … approximately 16% of children within four weeks of surgery and 26% of children while tubes are in place.3 Antibiotics

20. For persons who present with acute cough illness (ACI), what is the comparative effectiveness of various interventions for reducing inappropriate antimicrobial use? | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-persons-who-present-with-acute-cough-illness-aci-what-is-the-comparative-effectiveness-of-various-interventions-for-reducing-inappropriate-antimicrobial-use
    April 12, 2012 - , adverse drug effects, and antibiotic resistance. … It is also unclear why antibiotics prescribing practices vary in the management of ACI, despite efforts … of antibiotic resistance and adverse effects. … in the effectiveness of antibiotics in pediatric populations and subsets of adult patients with ACI … (e.g., with co-morbidities) who may derive modest benefit from antibiotics.