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effectivehealthcare-admin.ahrq.gov/products/copd/research
January 01, 2021 - Key Messages Antibiotic therapy increases the clinical cure rate and reduces the clinical failure rate … Antibiotics and corticosteroids are not associated with increase in serious adverse events. … Antibiotic therapy increases the clinical cure rate and reduces the clinical failure rate regardless … There is insufficient evidence to support a particular antibiotic regimen. … Systemic antibiotics and corticosteroids are associated with improved outcomes in mild and moderate to
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - Initially reserved for the sickest, highest-risk surgical patients,
drainage and antibiotic treatment … • Do the (comparative) effects and harms vary by route of administration of antibiotics,
type of antibiotic … , and duration of course of antibiotics? … versus No antibiotics or versus Alternative antibiotic regimen (for any
patient)
o Any class, route … to each
other and to placebo (or no antibiotics).
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effectivehealthcare-admin.ahrq.gov/products/diverticulitis/protocol
October 01, 2019 - Initially reserved for the sickest, highest-risk surgical patients, drainage and antibiotic treatment … Do the (comparative) effects and harms vary by route of administration of antibiotics, type of antibiotic … , and duration of course of antibiotics? … versus No antibiotics or versus Alternative antibiotic regimen (for any patient)
Any class, route … (C diff) infection
Antibiotic resistance
Interventional radiology comparisons:
Adverse
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effectivehealthcare-admin.ahrq.gov/sites/default/files/ebc-challenge-3rdplace_tympanic.pdf
January 26, 2013 - United States, viral and bacterial ear infections are the most common childhood illnesses treated with
antibiotics … Ceftriaxone, Cefdinir, Cefixime) (9)
Potential negative outcomes of antibiotic use:
1. … Antibiotic resistance
2. Allergic reactions
3. … Fluoroquinolone antibiotics are preferred due to their lack of ototoxicity (7). … If the infection appears to be more
than just localized then oral and sometimes even parenteral antibiotics
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effectivehealthcare-admin.ahrq.gov/sites/default/files/ebc-challenge-1stplace-qrmedica.pdf
January 01, 2013 - AOM is the most common childhood infection for
which antibiotics are prescribed in the United
States. … Antibiotic Options
Amoxicillin
Ampicillin
Cefdinir
Ceftriaxone
Azithromycin … Information on Antibiotic Use
There are a few options to try before an antibiotic; warm compresses, … Amoxicillin is still the safest, most least expensive antibiotic for patients without a penicillin allergy … Some liquid antibiotics, like Amoxicillin, need to be kept in the refrigerator.
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effectivehealthcare-admin.ahrq.gov/health-topics/pneumonia
November 25, 2024 - If bacteria are the cause, antibiotics should help. … Systematic Review Archived November 24, 2014
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Research Protocol Archived July 19, 2013
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Healthcare-Associated Infections
Systematic Review Archived October 5, 2012
Procalcitonin-Guided Antibiotic
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effectivehealthcare-admin.ahrq.gov/products/c-diff-infections/research-protocol
December 01, 2019 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. … Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review.
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effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
January 01, 2022 - Antibiotic treatment: For patients with uncomplicated diverticulitis, antibiotic treatment may not affect … symptoms, length of hospital stay, recurrence risk, quality of life, or need for surgery compared to no antibiotic … For patients who do receive antibiotics, the evidence is insufficient to guide choice of antibiotic regimen … For patients with uncomplicated acute diverticulitis, there is low SoE that antibiotic treatment does
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
September 13, 2012 - Antibiotics
Antibiotic use is prevalent in the management of skin ulcers, even in the absence of … The indications for the use of systemic or topical antibiotics are
not defined, but antibiotics have … Promotion of antibiotic resistance
c. Systemic absorption (rare)
3. … of antibiotics. … regimens
No systemic
antibiotics
Wound dressings
Systemic
antibiotics
Oral antimicrobials
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - , particularly broad-spectrum or multiple antibiotics. … Standard antibiotics treatments: metronidazole, rifampicin, rifaxamin, vancomycin. … Antibiotics: active treatments such as metronidazole or vancomycin. … Appropriate antibiotic usage
2. Positive environmental cultures
3. … Antibiotics and hospital-acquired Clostridium difficile-
associated diarrhoea: a systematic review.
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effectivehealthcare-admin.ahrq.gov/health-topics/critical-care
August 31, 2020 - Systematic Review Archived November 24, 2014
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Research Protocol Archived July 19, 2013
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic … Systematic Review Archived January 10, 2013
Future Research Needs on Procalcitonin-Guided Antibiotic … Low-Risk Women
Systematic Review Archived October 5, 2012
Procalcitonin-Guided Antibiotic
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effectivehealthcare-admin.ahrq.gov/products/tympanostomy-tubes/research-protocol
March 01, 2021 - for tube candidacy. 1 The American Academy of Pediatrics CPG discourages routine use of prophylactic antibiotics … drops versus systemic antibiotics or watchful waiting on duration of otorrhea, quality of life, or need … prophylaxis
KQ 5: Ototopical preparations
Ototopical antibiotics
FDA approved (i.e., … for recurrent episodes of AOM
Prophylactic antibiotics
Adenoidectomy
KQ 3: No comparator … water exposure
Avoidance of higher risk activities
KQ 5:
Watchful waiting
Oral (systemic) antibiotics
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effectivehealthcare-admin.ahrq.gov/products/venous-ulcers-treatment/research-protocol
December 01, 2019 - Antibiotics
Antibiotic use is prevalent in the management of skin ulcers, even in the absence of clinical … The indications for the use of systemic or topical antibiotics are not defined, but antibiotics have … , peripherally inserted central catheter (PICC) line and access infections
Promotion of antibiotic … Potential systemic antibiotic treatment options for chronic venous ulcers
See Table 2 for a list … of antibiotics.
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effectivehealthcare-admin.ahrq.gov/products/copd/protocol
January 01, 2019 - One uncertainty relates to the need for antibiotics in mild and moderately severe AECOPD, especially … of severe AECOPD, the need for antibiotics in less severe forms of COPD is unclear. 33 Uncertainty … , where safely possible, to reduce potential harms including development of antibiotic resistance, and … Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. … Antibiotic treatment in exacerbations of chronic obstructive pulmonary disease: Recent trial results.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fiber-intake-draft-report-appendix-c.xlsx
January 01, 2024 - constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … constipation or diarrhoea, regular use of NSAID, antacids, proton pump inhibitors, or H2 blockers, antibiotic … planned influenza vaccination or vaccination during the previous 12 mo, prebiotics or probiotics, or antibiotic … RCT cross-over < 1992 No industry funding NR Community Healthy smoking, antibiotic use within 6 mo 3 … home), **90 d before the study for antibiotic use and 14 d before the study for the (pro-, prebiotics
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
November 16, 2015 - tympanostomy tubes for children with
otitis media, indications for tympanostomy in children, prescription of antibiotics … drops versus systemic antibiotics or watchful
waiting on duration of otorrhea, quality of life, or … prophylaxis
• KQ 5: Ototopical preparations
o Ototopical antibiotics
§ FDA approved (i.e … for recurrent episodes of AOM
o Prophylactic antibiotics
o Adenoidectomy
• KQ 3: No comparator … Antibiotic use
3. Recurrent AOM/otorrhea (KQ 2)
4.
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effectivehealthcare-admin.ahrq.gov/health-topics/medication-errors
February 01, 2024 - Older Adults
Clinician Summary Archived April 6, 2016
Interventions To Improve Antibiotic … Respiratory Tract Infections
Systematic Review Archived January 27, 2016
Improving Antibiotic … Settings
Research Protocol Archived May 23, 2014
Interventions to Improve Appropriate Antibiotic
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effectivehealthcare-admin.ahrq.gov/products/c-difficile-update/clinician
December 01, 2019 - Lactobacillus probiotics, when used as an adjunct to antibiotic therapy, may prevent the recurrence of … diarrhea (≥3 loose stools in 24 hours) or ileus who have additional risk factors (including use of antibiotics … Antibiotic Stewardship
6
Appropriate prescribing practices were associated with decreased CDI. … The costs of the antibiotics used to treat CDI vary significantly. … What To Discuss With Your Patients and Their Caregivers
The role that use or overuse of antibiotics
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
July 01, 2023 - undergo transcatheter aortic valve
implantation (TAVI).20 It describes consensus on use of prophylactic antibiotics … 8
strong evidence supporting the necessity of dental care (other than routine prophylactic antibiotics … Rapid Response was not scoped to evaluate primary research studies on the efficacy
of prophylactic antibiotics … Historically, prophylactic antibiotics were used for the majority of patients perceived
to be at risk … Therefore, there is currently no scientific basis for the use of
prophylactic antibiotics before routine
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effectivehealthcare-admin.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
February 19, 2014 - § Antibiotic use
§ Gloves
§ Disposable thermometer
§ Handwashing/alcohol gel
§ Disinfection … component strategies
Key Question 3: What are the comparative effectiveness and harms of different
antibiotic … For a first recurrence, the
effectiveness of antibiotic therapy is around 60% and further declines with … What are the comparative effectiveness and harms of different antibiotic treatments?