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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - Current antibiotic dosing strategies also do not directly
consider the variety of antibiotic-resistance … Given the PK/PD properties of antibiotics, clinicians can
optimize the PD effects of antibiotics by … Among them are improving appropriate use of antibiotics
by promoting antibiotic use only when indicated … antibiotic doses. … concepts such as using extended or prolonged infusions
of time-dependent antibiotics.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - Antibiotic PD relates PK parameters to the
ability of an antibiotic to kill or inhibit growth of bacterial … , clinicians can optimize the PD effects of
antibiotics by altering the dosing methods for the antibiotic … Rates of antibiotic-related adverse events? … Rates of antibiotic-related adverse events? … ] OR "Anti-Bacterial Agents"[mesh])
Limits Humans
English language
Adults 19+ years or Adults 18
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effectivehealthcare-admin.ahrq.gov/health-topics/antibiotic-resistance
September 07, 2023 - Using antibiotics can lead to resistance. … Each time you take antibiotics, sensitive bacteria are killed. … To help prevent antibiotic resistance
Don't use antibiotics for viruses like colds or flu. … Antibiotics don't work on viruses.
Don't pressure your doctor to give you an antibiotic. … When you take antibiotics, follow the directions carefully.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - A key factor for the increased
rate of antibiotic resistance is high outpatient consumption
of antibiotics … Antibiotics are frequently inappropriately
used for uncomplicated acute RTIs. … ahrq.gov/antibiotics-RTI. … Available at www.effectivehealthcare.ahrq.gov/antibiotics-RTI. … http://www.effectivehealthcare.ahrq.gov/antibiotics-RTI
http://www.effectivehealthcare.ahrq.gov/antibiotics-RTI
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
January 01, 2016 - With antibiotic use, however,
some bacteria can adapt, which can
result in the development of antibiotic … of
new antibiotics, a key factor is high
outpatient consumption of antibiotics.1-3
In response to … Reduced overall prescribing or use of antibiotics for acute RTIs. … antibiotic prescribing, overall prescribing,
or antibiotic resistance (Key Questions 1 and 2), with … Data
were not available on appropriate antibiotic prescribing or
on antibiotic resistance.
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effectivehealthcare-admin.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol
December 01, 2019 - Antibiotic PD relates PK parameters to the ability of an antibiotic to kill or inhibit growth of bacterial … Concentration-dependent antibiotic: peak concentration to MIC ratio (C max /MIC)
Time-dependent antibiotic … , clinicians can optimize the PD effects of antibiotics by altering the dosing methods for the antibiotic … Rates of antibiotic-related adverse events? … ] OR "Anti-Bacterial Agents"[mesh])
Limits
Humans
English language
Adults 19+ years or
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
September 22, 2014 - antibiotics for acute RTI. … antibiotics!for!RTI!
! Improved!clinician!
knowledge!regarding!use!
of!antibiotics!for!RTI!
! … antibiotics!
KQ#1:#
! Improved!appropriate!
prescription!of!antibiotics!
! Improved!appropriate! … antibiotics!
KQ#2:!
! Antibiotic!resistance!
! Medical!complications!)e.g.!
Mortality,!Adverse! … Respiratory tract Infections-
Antibiotic Prescribing: Prescribing of antibiotics for self-limiting respiratory
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effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/clinician
December 01, 2019 - A key factor for the increased rate of antibiotic resistance is high outpatient consumption of antibiotics … Antibiotics are frequently inappropriately used for uncomplicated acute RTIs. … Deciding whether to prescribe antibiotics for acute RTIs is a complex process. … The factors associated with overuse of antibiotics for uncomplicated acute RTIs are numerous and diverse … Clinical Interventions (Delayed Versus Immediate Prescribing)
Delayed prescribing of antibiotics
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effectivehealthcare-admin.ahrq.gov/products/pneumonia-antibiotic-treatment/research
December 01, 2019 - pharmacokinetic/pharmacodynamic (PK/PD) measures or strategies to dose and monitor intravenous (IV) antibiotics … One trial (rated high risk of bias) used PK/PD measures to study the impact of different antibiotic dosing … Evidence is also insufficient to draw conclusions about the effect of continuous infusions of beta-lactam antibiotics … Clinical response, duration of mechanical ventilation, superinfection, rates of antibiotic-related adverse … https://effectivehealthcare.ahrq.gov/products/pneumonia-antibiotic-treatment/research
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effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research-protocol
December 01, 2020 - contributes to the development of antibiotic-resistant bacteria. 1 , 2 Reducing inappropriate antibiotic … with antibiotics and increases medical costs. … antibiotics for acute RTI. … Respiratory tract Infections-Antibiotic Prescribing: Prescribing of antibiotics for self-limiting respiratory … use / overall antibiotic use
KQ2: Antibiotic resistance and Medical complications (mortality, antibiotic
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effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/research
December 01, 2019 - use for acute RTIs for which antibiotics are not indicated. … We identified interventions that had evidence of reducing resistance to antibiotics, improving appropriate … prescribing (i.e., concordant with guidelines), or decreasing overall prescribing of antibiotics for … Actual use of antibiotics was also reported in too few studies to assess separately from prescribing. … https://effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/research
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effectivehealthcare-admin.ahrq.gov/health-topics/antibiotics
May 30, 2017 - Description
Antibiotics are powerful medicines that fight bacterial infections . … Using antibiotics when you don't need them, or not using them properly, can add to antibiotic resistance … This happens when bacteria change and become able to resist the effects of an antibiotic. … When you take antibiotics, follow the directions carefully. … Do not save antibiotics for later or use someone else's prescription.
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effectivehealthcare-admin.ahrq.gov/products/procalcitonin/research
December 01, 2019 - Outcomes were antibiotic use, mortality, morbidity, and adverse drug events of antibiotic therapy. … Procalcitonin guidance reduces antibiotic use when used to discontinue antibiotics in adult ICU patients … Conclusions
Procalcitonin guidance reduces antibiotic use when used to discontinue antibiotics in adult … ICU patients and to initiate or discontinue antibiotics in patients with respiratory tract infections … antibiotic resistance and for adverse events of antibiotic therapy.
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effectivehealthcare-admin.ahrq.gov/products/c-difficile-update/consumer
November 01, 2020 - Antibiotics
If your CDI happened after you took an antibiotic, your health care professional may have … Findings about antibiotics for CDI
Antibiotic
What did researchers find? … Possible side effects of antibiotics to treat CDI
Antibiotic
Possible Side Effects … Take all antibiotics exactly as instructed. … the antibiotic?
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effectivehealthcare-admin.ahrq.gov/products/procalcitonin-future/research
December 01, 2019 - Home
Evidence Reports
Future Research Needs on Procalcitonin-Guided Antibiotic … Early initiation of appropriate antibiotics and goal-directed therapies reduce mortality. … Conversely, overuse and misuse of antibiotics, including continuing antibiotics longer than necessary … for cure can result in adverse events and add to the increasing problem of antibiotic resistance. … Project Timeline
Future Research Needs on Procalcitonin-Guided Antibiotic Therapy
Jan 9, 2013
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
October 01, 2012 - Early initiation of appropriate
antibiotics and goal-directed therapies
reduces mortality. … Conversely, overuse
and misuse of antibiotics, including
continuing antibiotics longer than
necessary … In view of the present emphasis on the overuse of
antibiotics, other interventions to reduce antibiotic … ’s total
exposure to all antibiotics and is conventionally reported
as mean days per 1,000 days of … to all
antibiotics per 1,000 days of followup.
2.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_disposition-comments.pdf
January 27, 2016 - and that antibiotics could be
reduced overall. … message about antibiotics to
clinicians (“don’t prescribe antibiotics, but you
should give patients … Changed to “overuse of
antibiotics”
29. … use and antibiotic prescribing. … Peer Reviewer
#17 (TEP
Reviewer)
General Healthcare delivery, access to antibiotics,
antibiotic
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
August 01, 2014 - Conversely, overuse and misuse of antibiotics, including
continuing antibiotics longer than necessary … Conversely, overuse and misuse of antibiotics, including
continuing antibiotics longer than necessary … to discontinue antibiotics in adult ICU patients and to initiate or discontinue
antibiotics in patients … Consistent use of measures of total antibiotic exposure
(e.g. mean days total exposure to all antibiotics … Vulnerable to antibiotic
resistance and adverse effects
of antibiotics.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-update_consumer.pdf
May 01, 2017 - Antibiotics
If your CDI happened after you took an antibiotic, your health care
professional may have … you stop taking the antibiotic. … The antibiotic your doctor recommends may depend
on the availability and cost of the antibiotic, what … Take all antibiotics exactly as instructed. … the antibiotic?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
November 03, 2014 - uncertainty regarding indications for
Summary: tympanostomy in children as well as the prescription of antibiotics … drops
and/or systemic antibiotics for children with tympanostomy tube otorrhea (TTO)? … drops or systemic antibiotic administration
Comparator(s): Systemic antibiotic administration or topical … Should clinicians prescribe topical antibiotic eardrops and/or antibiotics for children
with uncomplicated … approximately 16% of children
within four weeks of surgery and 26% of children while tubes are in place.3 Antibiotics