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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - studies and secondary analyses of clinical trials may contain the most readily available evidence to answer … estimates of hazard, relative risk, or odds ratios.20–23 However, the questions a systematic review could answer … Step 5: Meta-Analysis of Estimates of Outcome Probabilities The most definitive level of evidence to answer
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
    June 01, 2011 - o “Do the studies have the appropriate research design to answer the key question(s)?” C. … The lack of information in existing studies to answer each of the component research questions from … The lack of information in existing studies to answer each of the component research questions, with … If a question is difficult to answer with the given literature, it becomes apparent. … − “Do the studies have the appropriate research design to answer the key question(s)?”
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-pilot-promote-entry-data-srdr_0.pdf
    October 01, 2019 - the individual study-specific cells in the MS Excel spreadsheets should be exact matches with the answer … extraction form section, where the data contained in the file are 8 represented as question-answer … separate data extraction form section, where the data contained in the file are represented as question-answer
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pilot-projects-supplementing-white-paper.pdf
    December 01, 2024 - Randomized controlled trials (RCTs) are considered the ideal study design to answer causal questions … RCTs alone is unlikely to address all information gaps, nor is it the appropriate study design to answer … preliminary scan of datasets to determine if the necessary data are available and of sufficient quality to answer
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
    December 09, 2009 - Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
    September 03, 2019 - This review is unable to answer many of the pre-determined questions. … reveals little comparability between the studies and how much more work needs to be done in order to answer … of experts and key informants, studies did not exist or were insufficient in design or number to answer … We agree with the reviewer that the literature was insufficient to answer many of the questions regarding
  7. Title (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
    March 31, 2010 - In summary, there are many questions that the previous reviews did not answer. … Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer … country, sample sociodemographic characteristics, intervention approach(s) and outcomes are designed to answer
  8. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
    January 01, 2009 - influencing benefits and harms often depend on distinct physiologic processes, and studies available to help answer … Clinical trials may provide evidence to answer a question about the applicability of a benefit but exclude
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insulin-analogues-disposition-081229.pdf
    September 01, 2008 - If it’s compared to a single injection of insulin the answer is yes, but when compared to basal-bolus … retrospective or prospective)" in the sentence to highlight different study designs that we think can answer … We understand that various factors are involved in the selection of study design to answer research … questions and one study design may not answer all clinically relevant questions. … We agree with the reviewer that review of large clinical databases may be a cost-effective way to answer
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_consumer.pdf
    May 01, 2011 - Managing Pain From a Broken Hip A Guide for Adults and Their Caregivers Is This Guide Right for Me or Someone I Care For? Yes, if: � You or the person you care for is an older adult (more than 50 years old) who is in a hospital because of a hip fracture (a broken hip that occurs suddenly from an event like a…
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
    May 27, 2014 - you. 5 Peer Reviewer 2 General Great questions asked but unfortunately they were not able to answer … For example on page 45: “We graded the SOE to answer KQs on the benefits and harms of the interventions … Thus to answer the “do” question, quantitative answers will need to be interpreted (criteria will need … to be developed and operationalized) to provide this dichotomous answer which often is not what reports … This may be a different set of interventions than what you would want to answer your original 30 day
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - may be sufficient to support conclusions about a new test if the following conditions are met: The answer … Principle 4: Sometimes It Is Sufficient To Focus Exclusively on Accuracy Studies (4 of 4) If the answer … Practice Question 1 (1 of 2) Practice Question 1 (1 of 2) Explanation for Question 1: The correct answer … Practice Question 2 (1 of 2) Practice Question 2 (1 of 2) Explanation for Question 2: The correct answer … Practice Question 3 (1 of 2) Practice Question 3 (1 of 2) Explanation for Question 3: The correct answer
  13. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - may be sufficient to support conclusions about a new test if the following conditions are met: The answer … Principle 4: Sometimes It Is Sufficient To Focus Exclusively on Accuracy Studies (4 of 4) If the answer … Practice Question 1 (1 of 2) Practice Question 1 (1 of 2) Explanation for Question 1: The correct answer … Practice Question 2 (1 of 2) Practice Question 2 (1 of 2) Explanation for Question 2: The correct answer … Practice Question 3 (1 of 2) Practice Question 3 (1 of 2) Explanation for Question 3: The correct answer
  14. effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
    January 01, 2013 - As a general guideline, the analyst should be able to answer three questions: Is the association robust … As a general guideline, the analyst should be able to answer three questions: Is the association robust
  15. effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
    February 01, 2008 - and VTE or bleeding, or describe the association between intermediate and final health outcomes to answer … arthroscopy, surgical repair of a lower extremity injury distal to the hip, or elective spine surgery to answer … Using all of the studies to answer a KQ, the applicability of the body of evidence will be determined
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
    February 01, 2008 - and VTE or bleeding, or describe the association between intermediate and final health outcomes to answer … arthroscopy, surgical repair of a lower extremity injury distal to the hip, or elective spine surgery to answer … Using all of the studies to answer a KQ, the applicability of the body of evidence will be determined
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
    December 17, 2013 - To properly answer switching questions, a review will likely need to incorporate both short- and long-term … Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - only synthesize the evidence, but also to identify the gaps in evidence that limited the ability to answer … The CER data from matched studies were insufficient to answer all other questions posed. … The draft PCA3 CER data from matched studies was insufficient to answer all other questions posed. … Therefore studies were combined and used to answer Key Questions 1 and 2 together. … Requesting such analyses be performed using existing datasets would help answer this question. 6.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
    November 07, 2012 - And if the answer is yes, which I think it must be, then what specifically must be done to obtain maximum … I am not sure of the answer to this question, but again a bit more on policy and research solutions … November 7, 2012 22 Commentator & Affiliation Section Comment Response Reviewer #5 General My answer … Reviewer #5 General The questions it sought to answer are clearly spelled out, as is the target population
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-acute-chronic_research-protocol.pdf
    February 15, 2017 - Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer … As the purpose of the DM is to address questions the SR alone cannot answer, the scope is dependent … criteria are (1) that some data are available on the topic, (2) that the SR is unlikely to be able to answer

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