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  1. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - 59 Abstract This chapter discusses considerations for comparator selection in observational comparative effectiveness research (CER). Comparison groups should reflect clinically meaningful choices in real world practice and be chosen based on the study question being addressed. Recognizing the implications and pote…
  2. effectivehealthcare.ahrq.gov/sites/default/files/implementation-package-unhealthy-alcohol-use-final.pdf
    September 01, 2018 - question is correctly answered as “number of times” not “number of drinks”, and being sure to select an answer
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-framework-protocol.pdf
    September 06, 2023 - This technical brief aims to answer the guiding questions with information from interviews with key
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/updating-criteria-qdr-protocol.pdf
    September 06, 2023 - This technical brief aims to answer the guiding questions with information from interviews with Key
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer … We will consider elements of the PICOTS framework when evaluating the applicability of evidence to answer
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
    October 24, 2019 - substance use disorder 5 Literature Search Strategies to Identify Relevant Studies to Answer … Inclusion/Exclusion of Studies in the Review Literature Search Strategies to Identify Relevant Studies to Answer
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
    January 01, 2023 - Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer … Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - Therefore, all studies meeting inclusion criteria are used to answer KQ1, but only those with a low … or moderate risk of bias are used to answer KQ2–5. … Studies with much larger sample sizes, enhanced applicability, and rich data to answer the question … treatments results in limited research, and from the limitations within that research of ability to answer
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
    April 28, 2010 - Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies To Answer … studies that presumably fulfill all quality criteria but do not report their methods sufficiently to answer … Grades reflect the strength of the body of evidence to answer KQs on the comparative effectiveness, … Comprehensive literature searches are not generally undertaken specifically to answer these questions
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-topic-refinement.pdf
    November 01, 2022 - amyloid for the treatment of Alzheimer’s disease indicates that, for coverage, the investigators must answer … production of real-world evidence, which we thought to be highly relevant because the data used to answer … design is methodologically appropriate, and the anticipated number of enrolled subjects is sufficient to answer … more rapid generation of evidence with involvement of the fewest patient participants as is needed to answer
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topics_methods.pdf
    January 01, 2010 - The priorities for research topics and the questions these topics should answer clearly vary by audience … Interviews with technical experts aim to answer questions such as: Why do proponents of one or another
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
    November 18, 2024 - To achieve this goal, the systematic review will answer the Key Questions (KQs) outlined below. … human-development-index#/indicies/HDI 10 Literature Search Strategies to Identify Relevant Studies to Answer … Rationale 11/18/2024 Section IV, Literature Search Strategies to Identify Relevant Studies to Answer … Inclusion/Exclusion of Studies in the Review Literature Search Strategies to Identify Relevant Studies to Answer
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
    July 01, 2010 - Searching for the Evidence: Literature Search Strategies for Identifying Relevant Studies To Answer … By using all of the applicable studies to answer a key question, the applicability of the body of evidence
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-integrating-health-system-data.pdf
    April 01, 2020 - health system data, often 2 unpublished, may be used alongside traditional systematic reviews to answer … the review itself, health system data can be formally incorporated into review findings, i.e., to answer … population level; therefore it is important to understand the extent to which the data source can answer … (and monitored for accuracy and completeness) from the EHR may inform its suitability for use to answer
  15. effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
    May 14, 2020 - Virtually none of the studies reviewed to answer the KQ were interventions applied AFTER the diagnosis … Introduction Peer Reviewer #4 The aims are very clearly stated and the approaches to answer them are … A 2-hr versus 4-hr action line on an undefined partogram does not answer the question of diagnosis of
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
    September 10, 2014 - When the available research evidence does not permit an answer to clinically important questions, the … We believe that this is a complex question, the answer to which would require consideration of the … [EPC note: this is an answer to a question soliciting the reviewers opinion regarding the adequacy of … If it currently exists, this report could dig deeper and answer harder questions than just image guided
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
    December 16, 2014 - We acknowledge that it will be difficult to find a definitive answer to these questions. … Yet the report rings hollow given its conclusion that future RCT’s remain necessary to answer the question … critical analysis of the results and a statement regarding overall failure of the research community to answer
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
    January 01, 2025 - Trauma Informed Care: A Systematic Review Systematic Review Trauma Informed Care: A Systematic Review Executive Summary Main Points Background and Purpose Exposure to adverse and potentially traumatic experiences is common and has been associated with negative mental and physical health out…
  19. effectivehealthcare.ahrq.gov/sites/default/files/selection-of-data-sources-chapter-8.pptx
    January 01, 2013 - sufficient length of followup Introduction Introduction Identifying appropriate data sources to answer … Secondary data is data collected for other purposes that can be used to answer the research question.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
    January 01, 2011 - Furthermore, the authors are correct in stating that it is unlikely that studies to answer the key questions

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