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381. Archived: Bladder Cancer in Adults: Screening, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-adults-screening-1996
     January 01, 1996 - significant hematuria varies, but more than 3-5 red blood cells (RBCs) per high-powered field in microscopic analysis … Urine screening strategy employing dipstick analysis and selective culture: an evaluation. … Isolated asymptomatic microhematuria: a cross-sectional analysis of test-positive and test-negative patients

382. Evidence Summary: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
     August 20, 2019 - Data Synthesis and Analysis For all KQs, the overall quality of evidence was rated good, fair, or poor … A systematic review and meta-analysis 150 of 8 placebo-controlled RCTs (n = 54,651) of tamoxifen, 151 … Meta-analysis of BRCA1 and BRCA2 penetrance. N Engl J Med . 2007;25(11):1329-1333.  17. … Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE. … c Based on evaluation including pedigree analysis, lifetime risk estimates from established models (

383. Evidence Summary: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ocular-prophylaxis-for-gonococcal-ophthalmia-neonatorum-preventive-medication
     January 29, 2019 - AHRQ staff provided project oversight, reviewed the report to ensure that the analysis met methodological … Otherwise, AHRQ had no role in the conduct of the study; collection, management, analysis, and interpretation

384. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/hhrqMCEgbsBMJ_Ppbcp4yJ
     January 14, 2025 - A pooled analysis of these studies found a statistically sig- nificant reduction in hip fractures and … A pooled analysis of 21 RCTs found no significant differ- ence in serious adverse events. … National analysis of comedications, comorbidity and survival. … Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis. … The accuracy of osteoporotic fracture risk prediction tools: a systematic review and meta-analysis.

385. Recommendation: Prostate Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening
     May 08, 2018 - This trade-off was also observed in a review of decision analysis models; screening protocols using lower … Potential Harms An analysis from the PLCO trial found that African American men were significantly … Decision analysis models suggest that given the higher rates of aggressive prostate cancer in African … Scandinavia estimated that genetic factors may account for up to 42% of prostate cancer risk. 18 An analysis … also commissioned a review of multiple contextual questions, including a review of existing decision analysis

386. Archived: Evidence Summary: Depression in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/depression-in-children-and-adolescents-screening
     February 08, 2016 - given to key confounders; and, for randomized, controlled trials, the lack of an intention-totreat analysis … of evidence for each key question using the system developed by the USPSTF. 18 Data Synthesis and Analysis … We used Comprehensive Meta Analysis, version 3 (Biostat), to calculate effect sizes and 95% CIs. … We planned to use meta-analysis to pool the efficacy outcomes by drug (such as escitalopram trials) and … A Bayesian meta-analysis. Clin Trials . 2006;3:73-90. [PMID: 16773951] 37.

387. Xt2Uhv4Qyluz8O2Hb A4Yq (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/xt2Uhv4qyLUZ8o2HB_a4YQ
     July 01, 2013 - Cost-Effectiveness Analysis The USPSTF’s deliberations on grade recommenda- tions for the effectiveness … In a retrospective subgroup analysis of 477 pa- tients, initiation of ART at CD4 counts less than 0.250 … In 1 modeling analysis, earlier initiation of ART combined with modifications in risky sexual behavior … Cost-effectiveness of strategies to improve HIV testing and receipt of results: economic analysis of … Prognosis of HIV-1- infected patients up to 5 years after initiation of HAART: collaborative analysis

388. Archived: Published Comment and Response: Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes?: Diabetes Mellitus (Type 2) in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/published-comment-and-response-do-lipid-lowering-agents-provide-a-greater-reduction-in-cardiovascular-events-among-patients-with-diabetes/diabetes-mellitus-type-2-in-adults-screening-2008
     November 15, 2008 - This recommendation seems to have been based, at least in part, on an analysis of the secondary prevention

389. Archived: Treatment: Evidence Summary: Gestational Diabetes Mellitus, Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/treatment-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
     May 28, 2013 - A Systematic Review and Meta-Analysis … Data Synthesis and Analysis Two independent reviewers graded the strength of evidence by using the … Preeclampsia events in our pooled analysis may have included women with the much-less-serious condition … Meta-analysis in clinical trials. Control Clin Trials . 1986;7:177-88. … Effects of treatment in women with gestational diabetes mellitus: systematic review and meta-analysis

390. Archived: Modeling Report: Lung Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report/lung-cancer-screening-december-2013
     July 30, 2013 - For this analysis, we prioritized the lung cancer mortality difference in the presence and absence of … reasons: 1) in NLST, almost all enrolled persons in the CT arm were screened, whereas in this cohort analysis … This comparative analysis did not quantify all potential harms from screening, including the number of … Subset and histological analysis of screening efficacy in the National Lung Screening Trial. … Evaluating test strategies for colorectal cancer screening: a decision analysis for the U.S.

391. doi:10.1016/S0749-3797(03)00122-3 (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWzpnYXDpQzUr8U_5xY6qS
     January 01, 2003 - New meta-analysis of treatment trials of hypertension: improving the estimate of therapeutic benefit. … Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome … Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized con- trolled trials … Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624–32. 30. … Effects of alcohol reduction on blood pressure: a meta-analysis of randomized controlled trials.

392. Archived: Lipid Disorders in Children: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-2007
     July 15, 2007 - familial hypercholesterolemia or familial combined hyperlipidemia), good quality evidence based on a meta-analysis … reducing intermediate outcomes: TC and LDL (percent mean reduction [95% confidence limits] from meta-analysis … monogenic dyslipidemia and fair-quality evidence in those with multifactorial dyslipidemia based on a meta-analysis … children with multifactorial dyslipidemia (percent mean reduction [95% confidence limits] from meta-analysis

393. JAMA (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4_pXjq7Egjwb_vjZZT-NGB
     May 01, 2021 - in 1 setting, lack of replication Slight imbalance in baseline characteristics not accounted for in analysis … CI, 0.45-0.90) NA, reasonably precise Only 1 health outcome reported, possible selective reporting Analysis … Acquisition, analysis, or interpretation of data: Henderson, Webber, Vesco. … AHRQ staff provided project oversight; reviewed the report to ensure that the analysis met methodological … service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis

394. Evidence Summary: Lipid Disorders in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/lipid-disorders-in-children-screening
     July 18, 2023 - Quantitative synthesis using random-effects meta-analysis. … Data Synthesis and Analysis All results were synthesized separately for FH and multifactorial dyslipidemia … AHRQ staff provided project oversight; reviewed the report to ensure that the analysis met methodological … Methods to calculate uncertainty in the estimated overall effect size from a random-effects meta-analysis … Blood cholesterol and vascular mortality by age, sex, and blood pressure: ameta-analysis of individual

395. Archived: High Blood Cholesterol and Other Lipid Abnormalities: Screening, 1996 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-cholesterol-other-lipid-abnormalities-screening-1996
     January 01, 1996 - Proportional hazards analysis of risk factors for coronary heart disease in individuals aged 65 or older … Matrix effects and the accuracy of cholesterol analysis. … Lipoprotein-cholesterol analysis during screening: accuracy and reliability. … Controversies in meta-analysis: the case of the trials of serum cholesterol reduction. … Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis.

396. Screening for Breast Cancer: Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Pboxx4DR35wz5GPozm-XNF
     June 15, 2023 - Meta-analysis of 3 large trials did not show a statistically significant difference in rates of in- terval … In intention-to-treat analysis, 2.2 per 1000 experienced interval breast cancer diagnoses in the supple … Acquisition, analysis, or interpretation of data: All authors. … Statistical analysis: Henderson. Administrative, technical, or material support: Webber, Melnikow. … Collaborative modeling to compare different breast cancer screening strategies: a decision analysis for

397. Draft Recommendation: Perinatal Depression: Preventive Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/perinatal-depression-interventions-to-prevent
     April 22, 2025 - include using exploratory questions (i.e., open-ended and clarifying questions), role-playing, decision analysis … , and communication analysis. 14 The interventions reviewed by the USPSTF varied in setting, timing, … Pooled analysis from seven trials showed a 21% reduction (RR, 0.79 [[95% CI, 0.70 to 0.88]]; I 2 =0%

398. Screening for Genital Herpes - Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_7ajXPWanAmoL_YtR72qFo
     March 01, 2005 - –13 There is limited evidence on the safety of antiviral treatments during pregnancy.25,26 A cost analysis … This analysis demonstrated that prophylactic acyclovir and follow-up of infants exposed to HSV during … Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis. … Genital Herpes: USPSTF Recommendations partners in the prevention of neonatal herpes: a health economic analysis

399. 4Nuuvs6Nmztdbgjbg3Elke (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
     January 01, 2020 - Data Synthesis and Analysis Because of the clinical heterogeneity across this body of evidence, we stratified … Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-88. [PMID: 3802833] 35. … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-58. [PMID: 12111919] 36. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34. … Analysis and interpretation of the data: J.S. Lin, E. O’Connor, C.V. Evans, C.A. Senger.

400. Grnjnsmqzvbc-Dnhgrmgg3 (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/gRNjNsmqZvBC-DnHGRMgG3
     December 01, 2014 - Data Synthesis and Analysis Two independent reviewers assessed the internal valid- ity (quality) of … AHRQ performed a final review of the manuscript to ensure that the analysis met methodological standards … This study used a more conser- vative approach to analysis that required complete sets of results from … A time trend analysis of a U.S. managed care population between 1997 and 2007 indicated in- creased cases … Analysis and interpretation of the data: B. Zakher, A.G. Cantor, M. Pappas, H.D. Nelson.