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181. Screening for Genital Herpes Simplex: A Brief Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZzZp7_aoJn73k9z25w_-qr
     March 01, 2005 - In an intention-to-treat analysis, famciclovir significantly delayed the time to the first recurrence … Intention-to-treat analysis indicated efficacy of 38% (95% CI, 18% to 68%) in study 1 and 42% (95% CI … In the post-hoc subgroup analysis, the vaccine provided higher levels of protection in women but not … Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis. … Analysis?

182. Evidence Summary: Weight Loss to Prevent Obesity-Related Morbidity and Mortality in Adults: Behavioral Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-adults-interventions
     September 18, 2018 - Details of the data analysis methods are included in the full report. … Meta-analysis in clinical trials. … Quantifying heterogeneity in a meta-analysis. … Bias in meta-analysis detected by a simple, graphical test. … Comparison of two methods to detect publication bias in meta-analysis.

183. Archived: Carotid Artery Stenosis: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-july-2014
     July 08, 2014 - A good-quality meta-analysis included studies published from 1966 to 2003 and used digital subtraction … A good-quality meta-analysis reported wide variation in measurement properties between laboratories, … Screening for Asymptomatic Carotid Artery Stenosis: A Systematic Review and Meta-Analysis for the U.S … Quantification of internal carotid artery stenosis with duplex US: comparative analysis of different … Screening for asymptomatic carotid artery stenosis: a systematic review and meta-analysis for the U.S

184. Archived: Final Evidence Summary: Obesity in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary39/obesity-in-children-and-adolescents-screening-2010
     January 15, 2010 - Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21(11):1539-1558. 16. … We report the more comprehensive results in the meta-analysis including all trials. … for inclusion in the meta-analysis. … c Result of analysis-of-variance testing interaction between treatment group and time. … Pooled analysis: short-term weight change effect size (ES) of behavioral interventions (KQ1).

185. Benefits and Harms of Prostate-Specific Antigen Screening for Prostate Cancer: An Evidence Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/NhXnjZM5ubvygH5GrqDZHC
     August 01, 2008 - Two poor-quality RCTs with important flaws in de- sign and analysis (Table 1) do not show a mortality … benefit from PSA screening independently or in a meta-analysis. … Finally, the inappro- priate analysis comparing screened with unscreened co- horts did not adjust for … A Cochrane meta-analysis (17) combined these 2 stud- ies by using an intention-to-screen analysis and … Screening decreases prostate cancer death: first analysis of the 1988 Quebec pro- spective randomized

186. Evidence Summary: Osteoporosis to Prevent Fractures: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
     January 14, 2025 - Data Synthesis and Analysis Data were synthesized in narrative and tabular formats. … Meta-analysis in clinical trials. Control Clin Trials . 1986;7(3):177-188. 15. Cochrane. … Quantifying heterogeneity in a meta-analysis. … Size of boxes indicates the weight of each study in the analysis. … The authors also reported a per-protocol analysis for 18,605 participants.

187. Archived: Modeling Report: Radiation-Induced Breast Cancer and Breast Cancer Death From Mammography Screening (Abstract): Breast Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report-radiation-induced-breast-cancer-and-breast-c/breast-cancer-screening-january-2016
     April 20, 2015 - In addition to the systematic reviews of the evidence, the USPSTF commissioned a decision analysis

188. Pgytn Cwqnmar9-3Du5Ste (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/PGYTn_cWQnmAr9-3du5StE
     February 01, 2016 - Associated With Rates of False-Positive and False-Negative Results From Digital Mammography Screening: An Analysis … Design: Analysis of registry data. Setting: Participating facilities at 5 U.S. … The AHRQ had no role in the analysis or the development of conclusions. … Family his- tory and the risk of breast cancer: a systematic review and meta- analysis. … Longitudinal data analysis using generalized linear models. Biometrika. 1986;73:13-22. 22.

189. Behavioral Interventions to Promote Breastfeeding - Recommendations and Rationale (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/rdNAq7uEUC2tNYV6_L9Qte
     January 01, 2010 - A meta-regression analysis of the available randomized controlled trials of breastfeeding interventions … The purpose of this analysis was to assess the independent effects of breastfeeding education, ongoing … In pooled analysis, education did not significantly increase breastfeeding duration at 4 to 6 months … In the meta-analysis conducted for the USPSTF,1 the independent effect of support alone on breastfeeding … In pooled analysis, the combined effects of education and support significantly increased breastfeeding

190. Final Recommendation Statement: Perinatal Depression: Preventive Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/perinatal-depression-preventive-interventions
     February 12, 2019 - , and communication analysis. 2 , 5 The interventions reviewed by the USPSTF varied in setting, intensity … However, pooled analysis did not demonstrate statistical significance (RR, 0.58 [95% CI, 0.22 to 1.53 … Postpartum mental health and breastfeeding practices: an analysis using the 2010-2011 Pregnancy Risk … The effects of postpartum depression on child development: a meta-analysis. … Violence as a risk factor for postpartum depression in mothers: a meta-analysis.

191. Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/AYu2UEtRFR765BEXVyftT2
     April 13, 2021 - the study and takes full responsibility for the integrity of the data and the accuracy of the data analysis … Acquisition, analysis, or interpretation of data:Henninger, Bean. … AHRQ staff provided project oversight, reviewed the report to ensure that the analysis met methodological … Otherwise, AHRQ had no role in the conduct of the study; collection, management, analysis, and interpretation

192. Archived: Final Evidence Review: Asymptomatic Bacteriuria in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review11/asymptomatic-bacteriuria-in-adults-screening-2008
     July 15, 2008 - Data Synthesis and Analysis Data from included studies were synthesized qualitatively in a narrative … A 2007 Cochrane systematic review and meta-analysis of randomized trials comparing antibiotic treatment … the studies included in the Cochrane review were published in 1987 or earlier, we considered the meta-analysis … A multivariate analysis, adjusted for patient age, length of follow-up, duration of diabetes, and presence … microbiologic or ecologic outcomes    Study design (n = 4):       Benefits: not an RCT, meta-analysis

193. Screening for Dyslipidemia in Younger Adults: A Systematic Review (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/SaASReVeD_fpHZQbeBZD5s
     October 01, 2016 - The AHRQ per- formed a final review of the manuscript to ensure that the analysis met methodological … Analysis and interpretation of the data: R. Chou, T. Dana, I. Blazina, C. Bougatsos, T.L. Jeanne. … In addi- tion, for RCTs, intention-to-treat analysis is used. … Intention-to-treat analysis is done for RCTs. … For RCTs, intention-to-treat analysis is lacking.

194. Archived: Coronary Heart Disease: Screening Using Non-Traditional Risk Factors | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/coronary-heart-disease-screening-using-non-traditional-risk-factors-2009
     October 15, 2009 - The available meta-analysis of individual data on ABI does not yield a clear picture on the proportion … Independent Predictive Value of Each Risk Factor ABI A recent well-conducted meta-analysis of 16 … This analysis did provide an unbiased estimate that approximately 10% of women would be reclassified … In a systematic review and meta-analysis of 4 good- and 11 fair-quality studies, 12 of the 15 found a … Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis.

195. PII: S0749-3797(01)00255-0 (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/yw_rbA_nQrCnkaN8X5t56S
     January 01, 2001 - Brunner et al.46 found a similar result (mean reduction of 3.7%) in their meta- analysis of 17 studies … A meta- analysis of 95 studies found that subjects assigned to exercise had TC levels after intervention … In a similar meta-analysis and meta-regression, Fager and Wik- lund69 reached the same conclusion. … Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies. … A meta- analysis of randomized controlled trials. Am J Public Health 1997;87:1415– 22. 47.

196. Evidence Summary: Ovarian Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/ovarian-cancer-screening
     February 13, 2018 - Good-quality trials also used intention-to-screen analysis and reported diagnostic criteria for outcome … Results of that analysis are potentially hypothesis generating but are more subject to bias than the … full intention-to-treat analysis of the trial. … Additional analyses of PLCO trial data include a recently published analysis adding up to 6 years of … e Extended from original protocol of 6 screening rounds based on interim analysis.

197. Screening and Behavioral Counseling Interventions to Reduce Alcohol Use in Adolescents and Adults: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/m_E9nFrmxuS5-surqVHK2u
     November 13, 2018 - Statistical analysis: O’Connor, Perdue, Jonas. … Random-effects model for meta-analysis of clinical trials: an update. … Bias in meta-analysis detected by a simple, graphical test. … Benefit-cost analysis of brief physician advice with problem drinkers in primary care settings. … Brief physician advice for problem drinkers: long-term efficacy and benefit-cost analysis.

198. Archived: Evidence Summary: Obesity in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
     June 20, 2017 - Random-effects meta-analysis was used to estimate the benefits of lifestyle-based programs and metformin … Meta-analysis in clinical trials. Control Clin Trials . 1986;7(3):177-188. Knapp G, Hartung J. … A likelihood approach to meta-analysis with random effects. Stat Med . 1996;15(6):619-629. … Quantifying heterogeneity in a meta-analysis. Stat Med . 2002;21(11):1539-1558. … Effectiveness of lifestyle interventions in child obesity: systematic review with meta-analysis.

199. Archived: Final Evidence Review: Hepatitis B in Pregnant Women: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review48/hepatitis-b-in-pregnant-women-screening-2009
     June 15, 2009 - Data Synthesis and Analysis We described and synthesized the data qualitatively in a narrative format … A meta-analysis of the 5 independent vaccination-placebo comparisons in these trials found that vaccination … In addition, a meta-analysis of 10 trials that contained 12 independent comparisons found that the combination … in newborn infants of mothers positive for hepatitis B surface antigen: systematic review and meta-analysis

200. Screening for Depression in Adults: A Summary of the Evidence (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/56vB_8UTTE_HjygLvJfYqM
     May 01, 2002 - To summarize the effect of screening on clinical outcomes, we performed meta-analysis by using RevMan … changes in clinical outcomes, we used meta-analysis to determine a summary estimate of effect. … , we performed an alternative analysis from which we excluded the latter trial (Figure 2). … Meta-analysis of the effect of screening and feedback on the proportion of patients with persistent … Meta-analysis of the effect of screening and feedback on the proportion of patients with persistent