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81. Safety of Vaccines Used for Routine Immunization in the United States | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/safety-vaccines/protocol
    April 06, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … Therapeutic vaccination for chronic hepatitis B: A systematic review and meta-analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi: 10.1111

82. Expanded Guidance on Selected Quantitative Synthesis Topics | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
    March 13, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three small … Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Investigating underlying risk as a source of heterogeneity in meta-analysis. … Statistical power analysis for the behavioral sciences, 2nd ed.

83. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
    September 01, 2013 - So how does one choose the underlying true model in a meta-analysis? … Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. … Meta-analysis of multiple outcomes by regression with random effects. … Meta- analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized … of a full Bayesian analysis.

84. Slide 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/introductory-slides-ahrq-cf-webinar.pdf
    August 27, 2012 - Stakeholder Preferences in Comparative Effectiveness Research: Potential Uses of Multi-Criteria Decision Analysis … approaches to eliciting and quantifying stakeholder preferences Compare and contrast Conjoint Analysis … reviews of existing research  Decision modeling, with or without cost information  Retrospective analysis … Chair of the ISPOR Conjoint Analysis (CA) Experimental Design Task Force. Dr. … Forum Team) 10:30-10:40 AM An introduction to the use of Analytical Hierarchy Process and Conjoint Analysis

85. Rt-Bone-Metatases-Qa-Tables-Appendix-F (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rt-bone-metatases-qa-tables-appendix-F.xlsx
    January 01, 2019 - Differential loss to followup acceptable Intent-to-treat analysis? Outcomes prespecified? … index publication) Unclear Unclear Yes Unclear No No Yes No Yes Unclear Yes Poor Howell, 2013 Subgroup analysis … 2005 (above) Unclear Unclear No Unclear No No Yes No No Unclear Unclear Poor Konski, 2006 Subgroup analysis … , 2006 (index publication) Yes Yes Yes No No No No Unclear Yes Unclear Yes Fair Sande, 2009 (sub analysis … Unclear No No Yes No Yes No Yes Fair Sprave, 2018 Quality of Life and Radiation-induced Secondary analysis

86. Cer-265-Radiation-Bone-Disease-App-F (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
    January 01, 2019 - Differential Loss to Followup Acceptable Intent-To-Treat Analysis? Outcomes Prespecified? … index publication) Unclear Unclear Yes Unclear No No Yes No Yes Unclear Yes Poor Howell, 2013 Subgroup analysis … 2005 (above) Unclear Unclear No Unclear No No Yes No No Unclear Unclear Poor Konski, 2006 Subgroup analysis … , 2006 (index publication) Yes Yes Yes No No No No Unclear Yes Unclear Yes Fair Sande, 2009 (sub analysis … Unclear No No Yes No Yes No Yes Fair Sprave, 2018 Quality of Life and Radiation-induced Secondary analysis

87. Dia 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
    January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis … (MCDA) and Conjoint Analysis (CA) Maarten J. … L3.2 = 0.5 L2,1 = 0.25 L2,2 = 0.25 L3,1 = 0.25 L3,1 = 0.25 4 Multi-criteria decision analysis … and Conjoint Analysis  Multi-criteria Decision analysis (MCDA) is a subdiscipline of operations … Conjoint analysis methods  Helps to improve judgment  Decomposed  Hierarchical  Low cognitive

88. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three … • Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Bayesian methods in meta-analysis and evidence synthesis. … Statistical power analysis for the behavioral sciences, 2nd ed.

89. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
    October 01, 2016 - , extreme value analysis, dimensional analysis).166 In addition, software production techniques, such … Meta-analysis, decision analysis, and cost-effectiveness analysis: methods for quantitative synthesis … Sensitivity analysis in the context of uncertainty analysis for computationally intensive models. … Sensitivity analysis versus uncertainty analysis: When to use what? … Bias analysis via missing-data methods.

90. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - To estimate treatment effects in clinically relevant subgroups (subgroup analysis) 2. … This type of analysis evaluates the treatment effect for a number of subgroups, one variable at a time … Subgroup Analysis Subgroup analysis is the most popular analytic approach for examining heterogeneity … The study intent, design, and analysis are all focused on the subgroup hypotheses to be tested. … Descriptive subgroup analysis The main goal of descriptive subgroup analysis is to describe the subgroup

91. Cer-235-Pharma-Nonpharm-Ptsd-Update-Appendix-G-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity • ≥20% differential on other demographic variables Yes: • Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group No: • Per-protocol analysis with ≤90% … extreme or high • Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals

92. Cer-235-Pharma-Nonpharm-Ptsd-Update-Appendix-G-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity • ≥20% differential on other demographic variables Yes: • Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group No: • Per-protocol analysis with ≤90% … extreme or high • Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals

93. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.

94. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.

95. Liver-Cancer Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - MRI and CT performed similarly when patients with HCC were the unit of analysis, but sensitivity was … higher for MRI than for CT when HCC lesions were the unit of analysis (pooled difference 0.09; 95% … Surveillance settings Unit of analysis: patients with HCC CT Sensitivity: Low Specificity: Low … Surveillance settings Unit of analysis: patients with HCC MRI or PET Insufficient No evidence … Nonsurveillance settings Unit of analysis: HCC lesions CT Sensitivity: Moderate Specificity:

96. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysis … Analysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.

97. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysis … Analysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.

98. S166 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
    October 01, 2007 - meta-analysis. … Systematic Reviews in Health Care: Meta-Analysis in Context. … Bayesian methods in meta analysis. In: Methods for Meta-Analysis n Medical Research. … Bayesian approaches to ran- dom-effects meta-analysis: a comparative study. … The random effects procedure is then followed as a normal meta-analysis of 2 studies.

99. Telehealth for Acute and Chronic Care Consultations | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/telehealth-acute-chronic/research-protocol
    February 16, 2017 - or/1-4 limit 5 to (meta analysis or systematic reviews) meta-analysis.pt. … meta-analysis/ or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic … (meta-analysis or systematic review).ti,ab. … meta-analysis/ or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic … (meta-analysis or systematic review).ti,ab.

100. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
     January 30, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … A Systematic Review and Meta- Analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi: