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  1. effectivehealthcare.ahrq.gov/products/safety-vaccines/protocol
    April 06, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … Therapeutic vaccination for chronic hepatitis B: A systematic review and meta-analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi: 10.1111
  2. effectivehealthcare.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
    March 13, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three small … Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Investigating underlying risk as a source of heterogeneity in meta-analysis. … Statistical power analysis for the behavioral sciences, 2nd ed.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
    September 01, 2013 - So how does one choose the underlying true model in a meta-analysis? … Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. … Meta-analysis of multiple outcomes by regression with random effects. … Meta- analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized … of a full Bayesian analysis.
  4. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/introductory-slides-ahrq-cf-webinar.pdf
    August 27, 2012 - Stakeholder Preferences in Comparative Effectiveness Research: Potential Uses of Multi-Criteria Decision Analysis … approaches to eliciting and quantifying stakeholder preferences Compare and contrast Conjoint Analysis … reviews of existing research  Decision modeling, with or without cost information  Retrospective analysis … Chair of the ISPOR Conjoint Analysis (CA) Experimental Design Task Force. Dr. … Forum Team) 10:30-10:40 AM An introduction to the use of Analytical Hierarchy Process and Conjoint Analysis
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rt-bone-metatases-qa-tables-appendix-F.xlsx
    January 01, 2019 - Differential loss to followup acceptable Intent-to-treat analysis? Outcomes prespecified? … index publication) Unclear Unclear Yes Unclear No No Yes No Yes Unclear Yes Poor Howell, 2013 Subgroup analysis … 2005 (above) Unclear Unclear No Unclear No No Yes No No Unclear Unclear Poor Konski, 2006 Subgroup analysis … , 2006 (index publication) Yes Yes Yes No No No No Unclear Yes Unclear Yes Fair Sande, 2009 (sub analysis … Unclear No No Yes No Yes No Yes Fair Sprave, 2018 Quality of Life and Radiation-induced Secondary analysis
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
    January 01, 2019 - Differential Loss to Followup Acceptable Intent-To-Treat Analysis? Outcomes Prespecified? … index publication) Unclear Unclear Yes Unclear No No Yes No Yes Unclear Yes Poor Howell, 2013 Subgroup analysis … 2005 (above) Unclear Unclear No Unclear No No Yes No No Unclear Unclear Poor Konski, 2006 Subgroup analysis … , 2006 (index publication) Yes Yes Yes No No No No Unclear Yes Unclear Yes Fair Sande, 2009 (sub analysis … Unclear No No Yes No Yes No Yes Fair Sprave, 2018 Quality of Life and Radiation-induced Secondary analysis
  7. Dia 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
    January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis … (MCDA) and Conjoint Analysis (CA) Maarten J. … L3.2 = 0.5 L2,1 = 0.25 L2,2 = 0.25 L3,1 = 0.25 L3,1 = 0.25 4 Multi-criteria decision analysis … and Conjoint Analysis  Multi-criteria Decision analysis (MCDA) is a subdiscipline of operations … Conjoint analysis methods  Helps to improve judgment  Decomposed  Hierarchical  Low cognitive
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three … • Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Bayesian methods in meta-analysis and evidence synthesis. … Statistical power analysis for the behavioral sciences, 2nd ed.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
    October 01, 2016 - , extreme value analysis, dimensional analysis).166 In addition, software production techniques, such … Meta-analysis, decision analysis, and cost-effectiveness analysis: methods for quantitative synthesis … Sensitivity analysis in the context of uncertainty analysis for computationally intensive models. … Sensitivity analysis versus uncertainty analysis: When to use what? … Bias analysis via missing-data methods.
  10. effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - To estimate treatment effects in clinically relevant subgroups (subgroup analysis) 2. … This type of analysis evaluates the treatment effect for a number of subgroups, one variable at a time … Subgroup Analysis Subgroup analysis is the most popular analytic approach for examining heterogeneity … The study intent, design, and analysis are all focused on the subgroup hypotheses to be tested. … Descriptive subgroup analysis The main goal of descriptive subgroup analysis is to describe the subgroup
  11. effectivehealthcare.ahrq.gov/sites/default/files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity • ≥20% differential on other demographic variables Yes: • Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group No: • Per-protocol analysis with ≤90% … extreme or high • Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity • ≥20% differential on other demographic variables Yes: • Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group No: • Per-protocol analysis with ≤90% … extreme or high • Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.
  14. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - MRI and CT performed similarly when patients with HCC were the unit of analysis, but sensitivity was … higher for MRI than for CT when HCC lesions were the unit of analysis (pooled difference 0.09; 95% … Surveillance settings Unit of analysis: patients with HCC CT Sensitivity: Low Specificity: Low … Surveillance settings Unit of analysis: patients with HCC MRI or PET Insufficient No evidence … Nonsurveillance settings Unit of analysis: HCC lesions CT Sensitivity: Moderate Specificity:
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysisAnalysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.
  17. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysisAnalysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.
  18. S166 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
    October 01, 2007 - meta-analysis. … Systematic Reviews in Health Care: Meta-Analysis in Context. … Bayesian methods in meta analysis. In: Methods for Meta-Analysis n Medical Research. … Bayesian approaches to ran- dom-effects meta-analysis: a comparative study. … The random effects procedure is then followed as a normal meta-analysis of 2 studies.
  19. effectivehealthcare.ahrq.gov/products/telehealth-acute-chronic/research-protocol
    February 16, 2017 - or/1-4 limit 5 to (meta analysis or systematic reviews) meta-analysis.pt. … meta-analysis/ or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic … (meta-analysis or systematic review).ti,ab. … meta-analysis/ or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic … (meta-analysis or systematic review).ti,ab.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
    January 30, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … A Systematic Review and Meta- Analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi:

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