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461. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - A published network meta-analysis of 212 trials found that clozapine was superior to other oral SGAs … This analysis found that all of the drugs included were superior to placebo. … Analysis of age subgroups did not find differences for comparisons of olanzapine with risperidone. … Cognitive remediation for negative symptoms of schizophrenia: A network meta- analysis. … A meta-analysis of controlled research on social skills training for schizophrenia.

462. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - We will deposit data used in a meta-analysis into the Systematic Review Data Repository (SRDR). … We anticipate performing a meta-analysis to describe the effects of treatment decisions on outcomes … The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

463. S116 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - To insure that the IV analysis was not biased by case-mix differences between physi- cians, we examined … between long-acting benzodiazepine prescribing and APM prefer- ence was no longer significant when the analysis … We restricted the analysis to just APM initiators to guard against selection bias among prevalent users … Longitudinal data analysis for discrete and con- tinuous outcomes. … Basic methods for sensitivity analysis of biases. Int J Epidemiol. 1996;25:1107–1116. 17.

464. Research White Paper - EPC Response to IOM Standards for Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/iom-standards_white-paper.pdf
     April 01, 2013 - STANDARD 4.3 Decide if, in addition to a qualitative analysis, the SR will include a quantitative analysis … (meta-analysis) 4.3.1 Explain why a pooled estimate might be useful to decision makers. 4. … Synthesizing Evidence Agree EPC guidance is presented in relation to ensuring that meta- analysis … Input is limited to protocol development and not results analysis. … , the systematic review will include a quantitative analysis (meta-analysis) 4.3.1 Explain why a pooled

465. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
     April 01, 2013 - o Data analysis was based on the intention-to-treat-principle. … Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177-88. … Assessing the amount of heterogeneity in random-effects meta-analysis. … STATA® Data Analysis and Statistical Software. MP Parallel ed. … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539-58.

466. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - For Key Question 4, on subgroups, conclusions are up to date, with the exception that one new meta-analysis … (Insufficient) A new meta-analysis concluded that no oral DMARDs were associated with increased … A new meta-analysis of 6 RCTs of tocilzumab + MTX vs. placebo7 showed increased risk of infection, … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 4. … Dixon, 2011b12 GCs Meta- analysis NA GCs Studies published before January 2010 21 RCTs and 42

467. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - For Key Question 4, on subgroups, conclusions are up to date, with the exception that one new meta-analysis … (Insufficient) A new meta-analysis concluded that no oral DMARDs were associated with increased … A new meta-analysis of 6 RCTs of tocilzumab + MTX vs. placebo7 showed increased risk of infection, … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 4. … Dixon, 2011b12 GCs Meta- analysis NA GCs Studies published before January 2010 21 RCTs and 42

468. Depression in Children: Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/childhood-depression/protocol
     August 24, 2018 - (i.e., meta-analysis) of the data from those studies. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report. … ”[pt] OR “meta-analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] OR … ”[pt] OR “meta-analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] OR … 2 #34 Search (#31 NOT (#19 or #21)) Sort by: Author Filters: Meta-Analysis; Systematic Reviews

469. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis—An Update of the 2006 Report. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
     October 01, 2011 - The sentence in question in the Executive Summary is referring to the finding in meta-analysis that … We revised to clarify (page 20, starting line 26): “A meta-analysis of 41 randomized trials found no … Patrick du Souich Results In page 52, based on the meta-analysis of Wandel et al.(1)it is stated … We did not identify a meta-analysis restricted to low- dose aspirin. … Each category of analgesics provided a detailed analysis.

470. Anxiety in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
     September 12, 2016 - If meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random effect method … to combine direct comparisons between treatments if the number of studies included in the analysis … We will evaluate the feasibility of conducting network meta-analysis to combine direct and indirect … Consistency of network meta- analysis will be evaluated using side-splitting models. … Meta-analysis in clinical trials. Controlled clinical trials. 1986 Sep;7(3):177-88.

471. Major-Depressive-Disorder Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
     December 01, 2015 - We examined potential sources of heterogeneity using sensitivity analysis or analysis of subgroups. … Network meta-analysis indicated response rates that did not differ statistically for patients on SGAs … In contrast, a second secondary analysis involving 727 patients, which was government funded, found … Statistical approaches for conducting network meta-analysis in drug development. … Antidepressant drug effects and depression severity: a patient-level meta-analysis.

472. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - • Regression analysis using regression coefficients and associated relative odds ratios. … This bias cannot be avoided by statistical analysis, but was addressed by stratifying analyses and … Using the most commonly reported comparator and analysis (tPSA and AUC), we performed a regression … A meta-analysis of the performance characteristics of the free prostate-specific antigen test. … A systematic review and meta-analysis. Prostate Cancer Prostatic Dis. 2006 9(4):374-8.

473. Ptsd-Adult-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
     April 01, 2013 - For each meta-analysis, we conducted sensitivity analyses by removing each study from the analysis … The analysis included both head-to-head and placebo-controlled trials. … Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: L. … Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: L. … Quantifying heterogeneity in a meta- analysis. Stat Med. 2002 Jun 15;21(11):1539-58.

474. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_executive.pdf
     October 01, 2010 - The most commonly reported of these were selected for meta-analysis, while the remaining outcomes were … Trials that enrolled patients with a range of pubertal status were excluded from subgroup analysis. … In one controlled trial, mean Tanner stage improved regardless of gender, and in an analysis of three … In one multivariate analysis, higher percent predicted FEV1 was associated with improvements in “ways … data merged and in a subgroup analysis.

475. Smoking Cessation Interventions During Pregnancy and the Postpartum Period | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/smoking-pregnancy-infants/research-protocol
     March 08, 2013 - The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … Multivariate analysis of factors associated with smoking cessation in women. … The validity of self-reported smoking: a review and meta-analysis. … the analysis, reporting, and claim of subgroup effects in randomized trials.

476. Smoking-Pregnancy-Infants Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/smoking-pregnancy-infants_research-protocol.pdf
     March 11, 2013 - The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … Multivariate analysis of factors associated with smoking cessation in women. … The validity of self-reported smoking: a review and meta-analysis. … the analysis, reporting, and claim of subgroup effects in randomized trials.

477. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/presentation.ppt
     August 01, 2009 - Various types of heterogeneity may preclude a quantitative synthesis (e.g., meta-analysis). … Why Not Meta-analysis? Even studies meeting the same inclusion criteria can vary. … Why Not Meta-analysis? … In theory, one can perform a meta-analysis when there are many filled cells across a row/SNP in a super … A forest plot is often used in presenting meta-analysis data, but it can also be useful when we are not

478. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - Furthermore, a large proportion of the effectiveness analysis focused on gabapentin and vigabatrin, … , are characteristically similar to that of their meta-analysis (OR 1.1 [0.9 to 1.2]). … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 5. … , are characteristically similar to that of their meta-analysis (OR 1.1 [0.9 to 1.2]). … analysis, the results were less likely to show significance.

479. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - Furthermore, a large proportion of the effectiveness analysis focused on gabapentin and vigabatrin, … , are characteristically similar to that of their meta-analysis (OR 1.1 [0.9 to 1.2]). … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 5. … , are characteristically similar to that of their meta-analysis (OR 1.1 [0.9 to 1.2]). … analysis, the results were less likely to show significance.

480. Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
     April 26, 2013 - A network meta-analysis of relapse-rate reduction using acamprosate, naltrexone, and placebo favored … (i.e., meta-analysis) of the data from those studies. … The analysis will include both head-to-head and placebo-controlled trials. F. … Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539-58.