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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0094_04-09-2009.pdf
January 01, 2009 - a pharmacological treatment versus a
pharmacological treatment combined with functional behavioral analysis … versus functional behavioral analysis alone for reducing such challenging
behaviors?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_surveillance.pdf
July 01, 2012 - For stereotactic and
ultrasound guided
combined, rate was 20.9%
in Yu’s meta-analysis and
22.0% in … Brennan (2011)
conducted a meta-analysis
of 52 studies including
7,350 lesions and found
needle size … Ductal carcinoma in situ at core-needle
biopsy: meta-analysis of underestimation
and predictors of … Outcome analysis of 9-gauge MRI-guided
vacuum-assisted core needle breast biopsies. … ND
Brennan,
2011--Ductal
Carcinoma18 US
11 or 14 gauge
CNB - assorted 7,350
Meta-analysis of
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Analysis of data on children will be
divided between us and this other EPC;
• Two new atypicals … A minimum of three studies is required for meta-analysis. … For trials that are judged sufficiently clinically similar to warrant meta-analysis, we will
estimate … For groups of trials not judged sufficiently clinically similar to support meta-analysis, we
will perform … The TEP does not do analysis of any kind
nor contribute to the writing of the report.
X.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
February 01, 2009 - In the FDA’s analysis, heart-related events (heart failure and sudden death) and infections
(mostly … We also used instrumental variable
(IV) analysis to provide estimates that would remain unbiased even … All confirmatory analyses were limited to outcomes found to be significant in the primary
analysis. … Risk
of death with atypical antipsychotic drug
treatment for dementia: meta-analysis of
randomized … Analysis using instrumental
variables. JAMA 1994;272:859-866.
18.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - Did the article include an intention-to-treat analysis, or provide the data needed to calculate it
( … run-in
NR/ 2-4
day
washout
no NA Pharmacia;
Pfizer
McKenna
(pooled
analysis of
three trials … provides a more detailed analysis
of CV events, however same data is used. … quality of included
studies not
considered in meta-
analysis
Multiple COX-2s (reported adverse … and 492 in
per-protocol analysis
Topical vs. oral diclofenac (intention-to-treat
analyses)
Mean
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - To determine the appropriateness of meta-analysis, we will consider the
clinical and methodological … Appropriate
measures will be chosen based on the type of data for meta-analysis. … Statistical heterogeneity will be explored
by using subgroup analysis or meta-regression. … When statistical meta-analysis is not possible, we will group studies by similarity of
intervention … Technical Experts do not do
analysis of any kind nor contribute to the writing of the report and have
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
December 01, 2015 - Meta-analysis of the clinical and laboratory
diagnosis of appendicitis. … A meta-analysis. Saudi Med J. 2007 Feb;28(2):173-80.
PMID: 17268692.
14. … MR imaging in cases of
antenatal suspected appendicitis--a meta-analysis. … A meta-analysis.
Radiology. 2006 Oct;241(1):83-94. PMID: 16928974.
17. … Bivariate
random effects meta-analysis of ROC curves.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - Meta-Analyst: software for meta-analysis of binary,
continuous and diagnostic data. … Systematic reviews in health care: meta-analysis in
context. 2nd ed. … Confidence intervals for the amount of heterogeneity in meta-analysis. … Assessing the amount of heterogeneity in random-
effects meta-analysis. … The use of numbers needed to treat derived from systematic reviews and meta-
analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - Thus, we also conducted a meta-analysis,
using a Bayesian approach to a logistic mixed-effects
6 … We did not find any cohort studies that had appropriate
information for inclusion in the meta-analysis … We were able to combine 23 of these studies into a robust
random-effects meta-analysis to quantify the … Our meta-analysis results suggested
that clinic reinforcement, peer support, and prescriptions
to quit … Efficacy and safety of
pharmacotherapy for smoking cessation among pregnant smokers:
a meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - We will perform random-effects meta-analysis using the Hartung-Knapp adjustment
when sufficient data … The
arcsine difference as a measure of treatment effect in meta-analysis with zero cells. … Meta-analysis of rare binary events in treatment groups with unequal
variability. … Bias in meta-analysis detected by a
simple, graphical test. BMJ. 1997;315:629-34
29. … Comparison of two methods to detect
publication bias in meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/comparator-selection-in-observational-chapter-5.pptx
January 01, 2013 - Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies … Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies … To overcome this limitation, an instrumental variable analysis using calendar time as an instrument has … Use of instrumental variables in the analysis of generalized linear models in the presence of unmeasured … Exposure time window
Period where therapeutic benefit and/or risk would plausibly occur
Sensitivity analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - examination of factors such as systematic error, random error, adequacy of
reporting, aspects of data analysis … e.g., the presence of disease or different stages/severity
of a disease).6 Each test included in the analysis … The results of
this analysis indicated that no conclusions could be drawn about the direction or relative … Analysis
Handling of indeterminate
results
A medical test can produce an uninterpretable result … (Yes/No/Unclear)
Were all patients included in the analysis?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
May 14, 2010 - Also included in AE analysis will be
articles identified through the search for specific AE, if any … Fracture outcomes data will be dually extracted from each article accepted for analysis by
a reviewer … Outcomes for which three or more publications have been
identified will be pooled for analysis. … For pooled analysis, we will assess heterogeneity and conduct sensitivity analysis. … The TEP does not do analysis of any kind
nor contribute to the writing of the report.
X.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - A systematic review and meta-analysis of observational studies. … Meta-analysis in clinical trials. Control Clin Trials.
1986 Sep;7(3):177-88. … Random-effects meta-analysis of
inconsistent effects: a time for change. … Bias in meta-analysis detected by a
simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34. … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
June 01, 2010 - The user will submit a query, which may be a simple menu-driven operation or an
executable analysis … data), an easy-to-use menu-driven query
interface, and the ability to manually execute distributed analysis … outcomes of interest, and extensive experience using these data sources for
post-marketing safety analysis … Secure analysis of
distributed chemical databases without data
integration. … “Secure” Log-Linear and Logistic Regression
Analysis of Distributed Databases.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
February 16, 2016 - We will deposit data used in a meta-analysis into the
Systematic Review Data Repository (SRDR). … For randomized controlled trials, was there an
intent-to-treat analysis? … Newer
approaches to random effects meta-analysis allow for robust (e.g., non-parametric)
estimates … for variables where it makes sense to do so, or subgroup analysis (with
random effects meta-analysis … Technical Experts do not do analysis of any kind nor do
they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
April 28, 2017 - o For Key Question 2b, we identified an in-process review that plans to conduct a
network meta-analysis … Telemedicine application in
the care of diabetes patients: systematic review and meta-analysis. … Effect of telemedicine on glycated
hemoglobin in diabetes: a systematic review and meta-analysis of … A systematic review and meta-analysis. … A systematic review and network meta-analysis of randomized
controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0855-170515.pdf
April 28, 2017 - o For Key Question 2b, we identified an in-process review that plans to conduct a
network meta-analysis … Telemedicine application in
the care of diabetes patients: systematic review and meta-analysis. … Effect of telemedicine on glycated
hemoglobin in diabetes: a systematic review and meta-analysis of … A systematic review and meta-analysis. … A systematic review and network meta-analysis of randomized
controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - Meta-analysis was carried out only for KQs 1 and 2. … Bivariate meta-analysis of sensitivity and
specificity with sparse data: a generalized linear mixed … Advanced methods
in meta-analysis: multivariate approach and meta-regression. … A bivariate
approach to meta-analysis. Stat Med. 1993;12(24):2273-84.
PMID: 7907813.
18. … of a full
Bayesian analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_disposition-comments.pdf
December 01, 2011 - analysis using Bayesian methods. … It
is my understanding that the term Network meta-analysis is used
in place of the longer term mixed … We agree that there could be
misunderstandings regarding the term “network
meta-analysis”. … In the original report we used a
method termed “network meta-analysis” by
Chumley. … The Trivedi study is a pooled analysis, and was
therefore ineligible for the efficacy section of
this