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421. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
     May 01, 2005 - have a high risk of bias for subgroup analysis. … have credible subgroup analysis. … How to use a subgroup analysis: users’ guide to the medical literature. … A tool to assess the quality of a meta‐analysis. Res Synth Methods. 2013;4(4):351-66. … Meta- analysis of observational studies in epidemiology: a proposal for reporting.

422. Prostate-Cancer-Therapies-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
     December 01, 2014 - ) of study participants to treatment groups, concealment of allocation, data analysis based on the … For the same reason, we performed only qualitative analysis in this update. … The SPCG-4 trial reviewed in the 2008 report performed subgroup analysis by age and had already found … vs. propensity scoring vs. multivariable regression analysis). … Prognostic value of the CAPRA clinical prediction rule: a systematic review and meta- analysis.

423. Stroke Prevention in Atr ial Fibr illation Patients: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
     October 27, 2017 - They had serious errors in design, analysis, or reporting; large amounts of missing information; or … We will then determine the feasibility of completing a quantitative synthesis (i.e., meta-analysis). … of intervention studies and 3 to consider meta-analysis of observational diagnostic test studies), … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta- analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta- analyses

424. skin-cancer-protocol-160810 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
     August 10, 2016 - We will synthesize data on important KC-related outcomes using network meta-analysis techniques, which … We will not include cancers of the genital areas or the mucosal surfaces of the lip in the analysis … We also plan to conduct a network meta-analysis to compare all treatment alternatives across studies … The exact methodology to conduct the network meta-analysis has not yet been determined, but we will … confer with international experts in network meta-analysis.

425. Kidney-Stone-Prevention Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
     June 15, 2011 - Testing may include an analysis of stone composition and biochemical evaluations of blood (e.g., calcium … Where data allow, the proposed systematic review and meta-analysis will comprehensively address all … The ratings may be used to conduct sensitivity analysis of results, such as by including and excluding … Meta-analysis of randomized trials for medical prevention of calcium oxalate nephrolithiasis. … TEP members will not perform analysis of any kind, or contribute to the writing of the report.

426. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
     October 01, 2021 - aspartate aminotransferase; CI = confidence interval; Ctrl = control; CV = cardiovascular; MA = meta-analysis … Number of events in control group ctrl_N Total N of control group RR Pooled risk ratio from meta-analysis … Number of events in control group ctrl_N Total N of control group RR Pooled risk ratio from meta-analysis … example, it may be possible to automate the creation of dot plots by taking data directly from Stata analysis … Graphical approaches to the analysis of safety data from clinical trials.

427. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
     November 09, 2011 - November 9, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Critical Analysis … Background and Objectives for the Systematic Review The critical systematic review and analysis of … The analysis will assess the evidence of the effectiveness of new safe practices and the adoption of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

428. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - Meta-analysis of test performance when there is a "gold standard." … Meta-analysis of Cohen's kappa. Health Serv Outcomes Res Method 2011; 11:145-63. 9. … Performance of Deming regression analysis in case of misspecified analytical error ratio in method … Meta- analysis of diagnostic tests with imperfect reference standards. … Random effects models in latent class analysis for evaluating accuracy of diagnostic tests.

429. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - • Comparator Analysis of efficacy: o No active treatment (sham stimulation) Analysis … Secondary data analysis, nonsystematic reviews, letters, or comments. … Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data. … Confidence intervals for the amount of heterogeneity in meta-analysis. … Assessing the amount of heterogeneity in random- effects meta-analysis.

430. Chicago-Area DEcIDE Center (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
     May 01, 2009 - Our quantitative analysis identified particular concerns with the off-label use of antipsychotic and … As a base analysis, we used a weighted average of the three scores with volume weighted at 0.5, safety … Our sensitivity analysis, however, suggested that the high ranking of quetiapine and risperidone did … L imitations A number of limitations associated with our analysis should be kept in mind. … Sensitivity analysis of rankings. Base model and variant models.

431. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
     June 06, 2011 - To determine the appropriateness of meta-analysis, we will consider the clinical and methodological … Appropriate measures will be chosen based on the type of data available for meta-analysis. … Statistical heterogeneity will be explored by using subgroup analysis or meta-regression. … When statistical meta-analysis is not possible, we will group studies by similarity of intervention … Closing the quality gap: a critical analysis of quality improvement strategies.

432. heart-failure-readmission-protocol-130611 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
     June 10, 2013 - An analysis of 2007 to 2009 Medicare claims data showed that 24.8 percent of beneficiaries admitted … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[All Fields] Additional … (i.e., meta-analysis) of the data from those studies. … Methods for Meta-Analysis in Medical Research (Wiley Series in Probability and Statistics – Applied … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539- 58.

433. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
     May 01, 2005 - have a high risk of bias for subgroup analysis. … have credible subgroup analysis. … How to use a subgroup analysis: users’ guide to the medical literature. … A tool to assess the quality of a meta‐analysis. Res Synth Methods. 2013;4(4):351-66. … Meta- analysis of observational studies in epidemiology: a proposal for reporting.

434. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - studies report sufficiently similar results, we will consider meta-analysis. … We expect to summarize harms data semiquantitatively (i.e., without meta-analysis). … studies report sufficiently similar results, we will consider meta-analysis. … We do not expect to include surgical interventions in this network meta-analysis since we expect the … The Decline of Elective Colectomy Following Diverticulitis: A Population-Based Analysis.

435. Systematic Review Update: Noninvasive Nonpharmacologic Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
     December 11, 2018 - To the extent that the interventions are distinct we will separate them out for analysis and reporting … of results) and quantitatively (meta-analysis) when appropriate. … If sufficient numbers of RCTs (>10) are available, quantitative funnel plot analysis may be done. … Random-effects meta-analysis of inconsistent effects: a time for change. … A likelihood approach to meta-analysis with random effects.

436. bipolar-disorder-treatment-protocol-140623 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
     June 23, 2014 - Data fields to be extracted will be determined based upon proposed summary analysis. … Data will be exported into Excel spreadsheets for descriptive analysis. … Similar to sensitivity analysis by risk of bias score, we will conduct sensitivity analyses by the level … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report … as topic/ 2 meta-­‐analy$.tw 3 metaanaly$.tw. 4 meta-­‐analysis/ 5 (systematic adj (review$1 or

437. Liver-Cancer-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer-therapy_research-protocol.pdf
     November 28, 2012 - In addition, intention-to-treat analysis is used for RCTs. o Fair. … Intention-to-treat analysis has been done for RCTs. o Poor. … o Did the analysis of outcome data incorporate a method for handling confounders such as statistical … If a meta- analysis can be performed, subgroup and sensitivity analyses will be based on assessment of … Fixed- and random-effects models in meta-analysis. Psychol Meth 1998;3(4):486-504. PMID: none 48.

438. Glaucoma-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-treatment_research-protocol.pdf
     November 16, 2010 - Since the analysis of intraocular pressure may vary appreciably by trial, we will consider other intraocular … We will develop a search strategy for MEDLINE, accessed via PubMed, based on an analysis of the medical … there are insufficient data (less than three studies), we will not combine the results in a meta-analysis … Subgroup analysis If there are sufficient data, we will conduct subgroup analyses by stage or severity … We will also conduct a subgroup analysis of studies in which the intervention is laser surgery or incisional

439. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
     November 16, 2010 - We will develop a search strategy for MEDLINE, to be accessed via PubMed, based on an analysis of the … there are insufficient data (less than three studies), we will not combine the results in a meta-analysis … Subgroup analysis If there are sufficient data, we will conduct subgroup analyses by stage or severity … We will also consider a subgroup analysis of studies that include asymptomatic participants who have … The TEP does not perform analysis of any kind nor does it contribute to the writing of the report.

440. Procalcitonin Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
     October 01, 2012 - (adjustment for potential confounders and intention-to-treat analysis). … A meta-analysis was performed on short-term mortality (28-day or in-hospital mortality) in a group … Meta-analysis was performed looking at early mortality across all five ICU studies. … Procalcitonin test in the diagnosis of bacteremia: a meta-analysis. … Good enough: a primer on the analysis and interpretation of noninferiority trials.