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401. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
     September 27, 2012 - In addition, intention-to-treat analysis is used for RCTs. o Fair. … Intention-to-treat analysis has been done for RCTs. o Poor. … o Did the analysis of outcome data incorporate a method for handling confounders such as statistical … If a meta- analysis can be performed, subgroup and sensitivity analyses will be based on assessment of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

402. Title (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
     March 31, 2010 - Project Title: Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis … Our analysis and inclusion of the different settings and diverse interventions along with a rigorous … meta-analysis of the findings will make unique contribution to the literature. … They had serious errors in design, analysis, or reporting; large amounts of missing information; or … Subgroup analysis: We will conduct subgroup meta-analyses when there are sufficient data (at least

403. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - This study is included in our analysis. … This study is included in our analysis. … These studies are included in the analysis. … This study is included in our analysis. … Remission is not clearly defined or consistent in the analysis.

404. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - Rationale for the Review This systematic review (SR) and meta-analysis will update the 2012 report, … Checking consistency in mixed treatment comparison meta-analysis. … Random-effects meta-analysis of inconsistent effects: a time for change. … Quantifying heterogeneity in a meta-analysis. … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[All Fields])) #16 Search

405. Slide 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
     August 27, 2012 - RTI International is a trade name of Research Triangle Institute. www.rti.org The Use of Conjoint Analysis … Duration 5 RTI International Research Triangle Institute Labels  Conjoint (consider jointly) analysis … Surrogate markers – Risk concepts  Consensus among researchers – Experimental design – Statistical analysis

406. Developing and Piloting a Tool To Create Dot Plots To Summarize Pooled Data for Multiple Outcomes in Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf
     October 01, 2021 - aspartate aminotransferase; CI = confidence interval; Ctrl = control; CV = cardiovascular; MA = meta-analysis … Number of events in control group ctrl_N Total N of control group RR Pooled risk ratio from meta-analysis … Number of events in control group ctrl_N Total N of control group RR Pooled risk ratio from meta-analysis … example, it may be possible to automate the creation of dot plots by taking data directly from Stata analysis … Graphical approaches to the analysis of safety data from clinical trials.

407. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-provider-adherence_research-protocol.pdf
     March 02, 2012 - Timing • Studies with all duration of follow-up will be included in the analysis. … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies: Volume 5—Asthma Care … Meta-analysis in clinical trials. Control Clin Trials 1986; 7(3):177-88. 37. … Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315(7109):629-34. 38. … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

408. Blood-Clots-Hip-Knee-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
     March 01, 2012 - Data Synthesis and Analysis We conducted meta-analyses when two or more RCTs adequate for pooling were … In a previous meta-analysis of 21 studies, regional anesthesia was associated with nonsignificantly … However, in the majority of cases, the number of trials in a subgroup analysis was too low to evaluate … Sensitivity Analyses: A “what if” analysis that helps determine the robustness of a study. … Statistical Heterogeneity: Variability in the observed effects among studies in a meta-analysis.

409. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
     December 01, 2011 - .73 The significance of this difference did not persist when a strict intention-to-treat analysis was … There is low-strength limited evidence from one subgroup analysis that a prebiotic may reduce diarrhea … One subgroup analysis of a single trial used a prespecified analysis, and the severity classification … , but not with strict intention to treat analysis. … Meta-analysis to assess risk factors for recurrent Clostridium difficile infection.

410. Data Points 17: Trends in Bariatric Surgery: Trends in bariatric surgery in Medicare beneficiaries (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery-trends_research.pdf
     November 01, 2012 - Procedure mix varies by age and region and changed over the period of analysis as lapa- roscopic operations … Analysis We assessed trends in procedure type across years (2006 to 2009; Table 1) and demographic … Outcomes varied slightly over the period of analysis (Figures 7, 8a, and 8b). … Bariatric surgery: a systematic review and meta-analysis. JAMA 2004;292(14):1724-37. 7. … Survival analysis: Techniques for censored and trun- cated data. 2nd ed.

411. Carbohydrate-Intake-Prepub-Final-Research-Table-Da (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-prepub-final-research-table-da.xlsx
     January 01, 2019 - exclusion criteria Objective of the study and whether it relates to the Key Questions Database or nutrient analysis … : removed all GDM; multivariate analysis for gestational age: BMI, prior GDM, infant sex, GDM, HDP, IOL … , c-section, GWG; multivariate analysis for birth centile: family history diabetes, GWG NR Foundation … 3 Brei, 2018 Prospective cohort / secondary analysis (from RCT) 208 Germany University hospital (single … (energy intake, infant sex, gestational age), p=0.03 Post-hoc analysis: p=0.15 NR NR NR NR NR NR NR

412. labor-dystocia-protocol-amended-160728 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
     July 28, 2016 - "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses … They had serious errors in design, analysis, or reporting; large amounts of missing information; or … We will then determine the feasibility of completing a quantitative synthesis (i.e., meta- analysis, … decision analysis, or simulation model). … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

413. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
     February 01, 2012 - Cost–Benefit Analysis A quality-adjusted cost–benefit analysis is recommended, comparing the incremental … A societal perspective should be assumed in the main analysis and the patient perspective in a sub-analysis … Analytic Approach Preference should be given to a Markov-chain, discreet events analysis. … A societal perspective should be assumed in the main analysis. … An important limitation of this approach is that the analysis is not controlled.

414. Tonsillectomy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
     February 10, 2016 - Specific  meta-­analysis  or  meta-­regression  will  depend  on  the  data  available.   …  (with  random  effects  meta-­analysis)  to  explore   heterogeneity  when  we  have  a  sufficient … A  re-­evaluation  of  random-­effects   meta-­analysis.   … Bayesian  nonparametric  meta-­analysis  using  Polya  tree   mixture  models.   … Bayesian   Analysis.  2006;;1(3):515-­33.          

415. head-neck-cancer-update-140204 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
     February 04, 2014 - If a meta-analysis can be performed, subgroup and sensitivity analyses will be based on assessment of … We will not use network meta-analysis due to the heterogeneity of the populations and treatments in … – Analysis: adjustment for potential confounders and intention-to-treat analysis. … In addition, intention-to-treat analysis is used for RCTs. Fair. … Intention-to- treat analysis has been done for RCTs. Poor.

416. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - , either in isolation or to update the existing meta-analysis. … Minimal Modeling Approaches to Value of Information Analysis for Health Research. … Evidence-based sample size calculations based upon updated meta-analysis. … A survival analysis. Ann Intern Med. 2007 August 21, 2007;147(4):224-33. 35. … Corticosteroids for pain relief in sore throat: systematic review and meta-analysis.

417. 04-E029-1 Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
     December 01, 2011 - We required multivariable analyses adjusting for a minimum of age and tumor stage (if the analysis was … One multivariable analysis reported that marital status was not associated with time to interruption … One analysis reported that having preferred provider organization or health maintenance organization … One multivariable analysis reported that insurance status was not a significant factor in predicting … Academic centers versus private practice One multivariable analysis reported that treatment facility

418. Adverse Effects of First-Line Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
     February 07, 2018 - We may consider study length for subgroup analysis if necessary. … The arcsine difference as a measure of treatment effect in meta-analysis with zero cells. … Meta-analysis of rare binary events in treatment groups with unequal variability. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34 22. … Comparison of two methods to detect publication bias in meta-analysis.

419. Disposition of Comments Report for Prevention of Healthcare-Associated Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
     November 30, 2012 - The methods, including search strategies, inclusion/exclusion criteria, are clearly defined and analysis … Maybe this is the result of the fact that while the analysis that forms the bulk of the report uses … However many failed to report sufficient data points or to use appropriate statistical analysis which … No statistical analysis was conducted. 3. This is a very comprehensive article. … No statistical analysis was conducted. 5.

420. Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
     May 29, 2013 - In response, the relative risk meta-analysis in the report has now been performed independantly in … For each meta- analysis, we have conducted sensitivity analysis to test the robustness of our results … We have only pooled studies when appropriate and have provided several sensitivity analysis Reviewer … Most of the data was not pooled in a meta-analysis for 6 of the 8 KQs. … The critical analysis of the data is exactly what is needed.