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41. Disposition of Comments for Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
    April 25, 2013 - The exception would be the decision analysis section. … change the results of the analysis (Table 36). … morality and had a weight of 19.3% in the analysis. … Systematic Reviews in Health Care; Meta-analysis in Context. … versus 2.72 (1.69, 3.74) reported in the AHRQ analysis.

42. Rapid Evidence Product_Nonemergent Percutaneous Coronary Intervention Versus Optimal Medical Treatment for Stable Ischemic Heart Disease: A Rapid Response Literature Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-evidence-heart-disease.pdf
    October 01, 2022 - In addition, intention-to-treat analysis is used. … Intention-to-treat analysis is used. … A 2023 SR and meta-analysis of randomized data by Bytyçi et al. … Finally, a systematic review and meta-analysis of PCI vs. … or when observational data was included in the meta-analysis.

43. Continuous-Outcomes-Quantitative-Synthesis Methods (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
    March 01, 2011 - Some recent research focuses on conducting nonparametric meta-analysis. … Two studies included in the meta-analysis used PACS. … Change from baseline and analysis of covariance revisited. … Applied Meta-analysis for Social Science Research. 1st ed. … Statistical Power Analysis for the Behavioral Sciences. 2nd ed.

44. Methods Guide for Medical Test Reviews (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
    July 01, 2012 - complex than the meta- analysis of interventions or associations. … Figure 8–2 illustrates this strategy for a meta-analysis of K studies. … This is the same analysis as in Table 8–2. Table 8–2. … Regression methods for meta-analysis of diagnostic test data. … Meta-analysis of test performance when there is a “gold standard.”

45. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
    June 10, 2013 - Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis. … But the analysis has several important gaps. … We have made many changes to improve the analysis. … The absence of analysis of resource intensity is striking. … No pooled analysis was done.

46. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
    April 11, 2018 - analysis" or "field study" or "field survey" or "field analysis" or "in vivo study" or "in vivo analysis … or study or analysis or survey)) or "replication study" or "replication analysis " or "replication trial … analysis" or "field study" or "field survey" or "field analysis" or "in vivo study" or "in vivo analysis … study or analysis or survey)) or "replication study" or "replication analysis " or "replication trial … " or "feasibility study" or "feasibility analysis" or "trend study" or "trend survey" or "trend analysis

47. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
    September 01, 2012 - Ethical, legal, and social issues Meta-analysis uses existing data. … Setting Secondary analysis of preexisting data. … An analysis of an existing registry, a standard meta-analysis, or a meta-analysis of individual patient … Ethical, legal, and social issues Meta-analysis uses existing data. … stratum or subgroup for analysis; clinical stage of the disease.

48. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - The main goals of HTE analysis are to estimate treatment effects in clinically relevant subgroups and … Subgroup analysis is the most common analytic approach for examining HTE. … , on the other hand, has been extensively studied.6 Hence, we will focus on subgroup analysis. … Subgroup Analysis Subgroup analysis is the most commonly used analytic approach for examining HTE. … Descriptive Subgroup Analysis The main goal of descriptive subgroup analysis is to describe the subgroup

49. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
    September 01, 2013 - So how does one choose the underlying true model in a meta-analysis? … Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. … Meta-analysis of multiple outcomes by regression with random effects. … Meta- analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized … of a full Bayesian analysis.

50. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three … • Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Bayesian methods in meta-analysis and evidence synthesis. … Statistical power analysis for the behavioral sciences, 2nd ed.

51. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
    October 01, 2016 - , extreme value analysis, dimensional analysis).166 In addition, software production techniques, such … Meta-analysis, decision analysis, and cost-effectiveness analysis: methods for quantitative synthesis … Sensitivity analysis in the context of uncertainty analysis for computationally intensive models. … Sensitivity analysis versus uncertainty analysis: When to use what? … Bias analysis via missing-data methods.

52. Dia 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
    January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis … (MCDA) and Conjoint Analysis (CA) Maarten J. … L3.2 = 0.5 L2,1 = 0.25 L2,2 = 0.25 L3,1 = 0.25 L3,1 = 0.25 4 Multi-criteria decision analysis … and Conjoint Analysis  Multi-criteria Decision analysis (MCDA) is a subdiscipline of operations … Conjoint analysis methods  Helps to improve judgment  Decomposed  Hierarchical  Low cognitive

53. Slide 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/introductory-slides-ahrq-cf-webinar.pdf
    August 27, 2012 - Stakeholder Preferences in Comparative Effectiveness Research: Potential Uses of Multi-Criteria Decision Analysis … approaches to eliciting and quantifying stakeholder preferences Compare and contrast Conjoint Analysis … reviews of existing research  Decision modeling, with or without cost information  Retrospective analysis … Chair of the ISPOR Conjoint Analysis (CA) Experimental Design Task Force. Dr. … Forum Team) 10:30-10:40 AM An introduction to the use of Analytical Hierarchy Process and Conjoint Analysis

54. Slide 1
    effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - To estimate treatment effects in clinically relevant subgroups (subgroup analysis) 2. … This type of analysis evaluates the treatment effect for a number of subgroups, one variable at a time … Subgroup Analysis Subgroup analysis is the most popular analytic approach for examining heterogeneity … The study intent, design, and analysis are all focused on the subgroup hypotheses to be tested. … Descriptive subgroup analysis The main goal of descriptive subgroup analysis is to describe the subgroup

55. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.

56. Disposition of comments_Comparative Effectiveness Review No. 242: Radiation Therapy for Brain Metastases (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
    June 09, 2021 - TEP #6 General Cost analysis – SRS can generate huge bills. Something to note. … analysis and outcome in sufficient detail. … It was clear the reason of not included meta-analysis. Noted. … Was the analysis conducted with incorrectly assigned trials? … Consider pooling these analysis (but do include the separate analysis as well)grammatical page 18

57. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
    January 30, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … A Systematic Review and Meta- Analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi:

58. Version-3-Immunity-After-Covid-19-Appendix-Table-B-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
    January 24, 2022 - N1 total positive cohort included in analysis N2 total negative (control) cohort included in analysis … Delta analysis, and before August 30, 2020 for long-term effectiveness analysis Delta virus analysis … effectiveness analysis: 11,186 Delta analysis: 274,830 Long-term effectiveness analysis: 141,417 Delta … analysis: 40 Long-term effectiveness analysis: 81 Delta analysis: 50,287 Long-term effectiveness analysis … : 11,105 Delta analysis: 1,494 Long-term effectiveness analysis: 7,167 Delta analysis: 273,336 Long-term

59. Liver-Cancer Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - MRI and CT performed similarly when patients with HCC were the unit of analysis, but sensitivity was … higher for MRI than for CT when HCC lesions were the unit of analysis (pooled difference 0.09; 95% … Surveillance settings Unit of analysis: patients with HCC CT Sensitivity: Low Specificity: Low … Surveillance settings Unit of analysis: patients with HCC MRI or PET Insufficient No evidence … Nonsurveillance settings Unit of analysis: HCC lesions CT Sensitivity: Moderate Specificity:

60. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysis … Analysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.