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381. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - One meta-analysis published in 2002 included 10 trials, while another published in 2004 included only … Our analysis of this example showed that included study designs varied among reviews. … A meta-analysis incorporating prior knowledge of anti-fracture efficacy in women. … Meta-analysis of alendronate for the treatment of postmenopausal women. … University of Pennsylvania Meta-analysis Blinding Study Group.

382. Amended Protocol: Interventions for Breathlessness in Patients with Advanced Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
     May 19, 2020 - We will develop a search strategy for PubMed, based on an analysis of the medical subject headings ( … If substantial heterogeneity is found, we will conduct sensitivity analysis when applicable, as well … as conduct a meta-regression analysis if covariate information (e.g., age, sex) is available. … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

383. Nppv-Respiratory-Failure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
     July 01, 2012 - We then determined the feasibility of completing a quantitative synthesis (i.e., meta-analysis). … quantitatively using the Comprehensive Meta-Analysis software (Version 2; Biostat, Englewood, NJ). … Mortality is a dichotomous outcome and was fitted using multiple logistic regression analysis. … Meta-analysis: noninvasive ventilation in acute cardiogenic pulmonary edema. … Meta-analysis of multitreatment studies. Med Decis Making. 1998;18(1):37-43. PMID: 9456207. 53.

384. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
     July 27, 2023 - The MHS I report centered its analysis on the interventions for heparin, focusing on the implementation … A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight … In: Making Healthcare Safer II: An Updated Critical Analysis of the Evidence for Patient Safety Practices … In: Making Healthcare Safer III: A Critical Analysis of Existing and Emerging Patient Safety Practices … The MHS I report centered its analysis on the interventions for heparin, focusing on the implementation

385. Evaluation of Dietary Protein Intake Requirements (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
     November 28, 2023 - Current DRIs were established based on analysis of available nitrogen balance studies, which tend to … .24 When meta-analysis is not possible, we will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a narrative Summary of Findings table. … Meta-Analysis with R. 2015. 27. Higgins JP, Thompson SG, Deeks JJ, Altman DG.

386. Behavioral Interventions for Migraine Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bimp-protocol.pdf
     September 27, 2022 - all preventive behavioral therapy options.8-10 Similarly, although a recently published network meta-analysis … • ≥80% of study participants had migraine headache, or the study reports a subgroup analysis … We will summarize the evidence both qualitatively and quantitatively (e.g., meta-analysis, network meta-analysis … Efficacy of psychological treatment for headache disorder: a systematic review and meta-analysis. … Nonpharmacological interventions for pediatric migraine: a network meta-analysis.

387. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
     May 01, 2010 - Framework for analyzing outcomes for rFVIIa use Premier Database Analysis to Assess In-Hospital Use … Data Measures and Unit of Analysis We classified hospitalizations where rFVIIa use was reported into … The unit of analysis was any hospital “case” of rFVIIa use—defined as any application during a patient … Statistical Analysis The goals of our statistical analysis of the Premier database were: (1) to provide … of the research available on the spectrum of rFVIIa off-label use (Key Question 1), (b) analysis of

388. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - Data Analysis and Synthesis For comparing imaging tests, we synthesized the evidence using meta-analysis … A figure of the meta-analysis appears in Figure A below. … A figure of the meta- analysis appears in Figure B. … A figure of the meta-analysis appears in Figure C. … FDG-PET in diagnosis, staging and prognosis of pancreatic carcinoma: a meta-analysis.

389. Progestogens-Preterm-Birth Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
     September 01, 2012 - Meta-Analysis We conducted a Bayesian meta-analysis to provide aggregate estimates of the effectiveness … Interpretation of Meta-Analysis In the Results section of the full report, we report the findings from … meta-analysis as odds ratios (OR) from Bayesian models. … The relationship between number of injections and outcome was examined in a single database analysis … We calculated meta-analysis estimates by using RCTs grouped by progestogen formulation (17OHP, oral,

390. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
     February 15, 2018 - Peer Reviewer 2 General Comments This is a very well-written report that contains a thorough analysis … The Lung Association appreciates the analysis conducted with this report and provides the following … During peer review we also conducted a Qualitative Comparative Analysis to augment the analysis. … During peer review we also conducted a Qualitative Comparative Analysis to augment the analysis. … During peer review we also conducted a Qualitative Comparative Analysis to augment the analysis.

391. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - We will determine the feasibility of a quantitative synthesis (i.e., meta-analysis). … The worldwide prevalence of ADHD: a systematic review and metaregression analysis. … The use of actigraphy in the monitoring of sleep and activity in ADHD: A meta-analysis. … a systematic review and meta-analysis. … "[pt] OR "meta- analysis as topic"[MeSH] OR "meta-analysis"[tiab] OR "metaanalyses"[tiab]) NOT (Editorial

392. Obesity-Child Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
     March 31, 2010 - Review Number 115 Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis … Our meta- analysis reported magnitude of effect. … The meta-analysis, which included four studies, was not statistically significant (p = 0.219). … To allow for such analysis we may need larger studies, which will be more costly. … Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis.

393. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
     May 02, 2011 - Evidence-based Practice Center Systematic Review Protocol Project Title: Serum-Free Light Chain Analysis … Analytic framework for serum--free light chain analysis for the diagnosis, management, and prognosis … If the studies do not directly compare the tests of interest, we will use network analysis to estimate … International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

394. Disposition of Comments for Self-Measured Blood Pressure Monitoring: Comparative Effectiveness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
     January 01, 2012 - “In a sensitivity meta-analysis that included only the three quality A or B studies, a statistically … The appendix describing those studies not included in the analysis was very helpful. … “In a sensitivity meta-analysis that included only the three quality A or B studies, a statistically … • Suggest mentioning race/ethnicity data that was abstracted and whether any subgroup analysis … Peer Reviewer 2 General An exhaustive, well written analysis of a clinically important issue.

395. Cad-Pci-Bypass Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
     May 01, 2013 - Grafting for Coronary Artery Disease, was released in October 2007.1An individual patient data meta-analysis … Two of three experts responded that the broad conclusion of the 2009 individual patient meta- analysis … surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 5. … intervention versus coronary artery bypass graft surgery in left main coronary artery disease: a meta-analysis

396. Pharmacologic and Nonpharmacologic Treatments of Posttraumatic Stress Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
     October 24, 2019 - Methodological differences, such as data coding approaches and combining treatment categories for analysis … Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … Did the study use intention-to-treat analysis? j.

397. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
     January 01, 2012 - To overcome this limitation, an instrumental variable (IV) analysis using calendar time as an instrument … In addition, performing both an as-treated analysis (where patients are censored at the end of the … Use of instrumental variables in the analysis of generalized linear models in the presence of unmeasured … Analysis of survival by tumor response. J Clin Oncol. November 1, 1983;1(11):710-9. 30. … Specificity of hospital volume-outcome associations for surgical procedures: analysis of administrative

398. Title (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
     March 31, 2010 - Project Title: Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis … Our analysis and inclusion of the different settings and diverse interventions along with a rigorous … meta-analysis of the findings will make unique contribution to the literature. … They had serious errors in design, analysis, or reporting; large amounts of missing information; or … Subgroup analysis: We will conduct subgroup meta-analyses when there are sufficient data (at least

399. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
     September 27, 2012 - In addition, intention-to-treat analysis is used for RCTs. o Fair. … Intention-to-treat analysis has been done for RCTs. o Poor. … o Did the analysis of outcome data incorporate a method for handling confounders such as statistical … If a meta- analysis can be performed, subgroup and sensitivity analyses will be based on assessment of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

400. Disposition of Comments Report for Comparative Effectiveness Review No. 131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
     February 25, 2014 - This study is included in our analysis. … This study is included in our analysis. … These studies are included in the analysis. … This study is included in our analysis. … Remission is not clearly defined or consistent in the analysis.