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341. A Rapid Evidence Review of Retention Strategies for Medications for Addiction Treatment (MAT) in Adults with Opioid Use Disorder | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/retention-strategies-opioid-use-disorder/rapid-protocol
     May 08, 2019 - We will not conduct a meta-analysis or do a formal process to grade the strength of evidence. … Analysis of Subgroups or Subsets As data are available and time allows, we will examine whether the … Effects of medication-assisted treatment on mortality among opioids users: a systematic review and meta-analysis … Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of

342. Omega-3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
     August 12, 2016 - Raitt 2005 is in the current meta-analysis. … Raitt 2005 is in the current meta-analysis. … included approximately two thirds fewer RCTs compared to the GOED-sponsored meta-analysis. … compared to the GOED-sponsored meta-analysis. … As noted, it was necessary to restrict the number of studies for analysis.

343. Disposition of Comments Report for Decision Aids for Cancer Screening and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
     December 23, 2014 - It also adds to the knowledge base through the detailed analysis of effect modifiers. … A meta-analysis was done. … The endorsed analysis (hierarchical random effects meta-regression analysis) could incorporate both … We did not undertake a subgroup analysis specific to PSA testing. … We refer to (Bayesian analysis) credible intervals.

344. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - Deviations from the protocol’s analysis plan may be suggestive of selective analysis reporting. … ), or a change in statistical significance (by meta-analysis). … Detecting and adjusting for small-study effects in meta-analysis. … Meta-analysis, funnel plots and sensitivity analysis. Biostatistics. 2000 Sep;1(3):247-62. … INTENTION-TO-TREAT analysis?

345. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - In 2008, Schmitt and colleagues published a meta-analysis analyzing the efficacy and tolerability of … Systematic reviews with or without meta-analysis will be included for manual reference searching as … We will conduct sensitivity analysis limiting the analysis to only trials rated as good quality. … For example, when a meta-analysis is performed, we will evaluate the confidence interval around the … Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88. PMID: 3802833. 22.

346. Effect-Dietary-Digestible (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
     January 01, 2021 - one year and puberty are likely sparse.15 Purpose of the Review This systematic review and meta-analysis … We will use relevant systematic reviews and meta-analysis to identify additional existing and new literature … If a meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates from … Carbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysis … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

347. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pharma-nonpharma-protocol.pdf
     September 01, 2021 - Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … 2.6) Was an appropriate analysis used to estimate the effect of assignment to intervention? … that was finalized before unblinded outcome data were available for analysis?

348. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
     October 01, 2022 - Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … 2.6) Was an appropriate analysis used to estimate the effect of assignment to intervention? … that was finalized before unblinded outcome data were available for analysis?

349. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
     January 01, 2021 - Hand Searching: Reference lists of relevant, recent, high-quality systematic reviews or meta- analysis … Analysis type of primary PTSD outcome measure (ITT, completer) d. … Statistical analysis method for primary PTSD outcome e. … 2.6) Was an appropriate analysis used to estimate the effect of assignment to intervention? … that was finalized before unblinded outcome data were available for analysis?

350. Interventions to Improve Care of Bereaved Persons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
     June 01, 2023 - We will abstract the treatment approach in detail together with the study design, analysis, and any … We will use meta-analysis as a data-aggregation technique with appropriate meta-analysis models39 which … Widowhood and mortality: a meta-analysis and meta-regression. … The prevention and treatment of complicated grief: a meta-analysis. … Bias in meta-analysis detected by a simple, graphical test.

351. Psychosocial and Pharmacologic Interventions for Disruptive Behavior Disorder | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/disruptive-behavior-disorder/research-protocol
     July 01, 2014 - We will examine the appropriateness of each study for inclusion in a meta-analysis. … The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. … the analysis, reporting, and claim of subgroup effects in randomized trials.

352. Comparative Effectiveness of Adjunctive Devices to Remove Thrombi or Protect Against Distal Embolization in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention of Native Vessels | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/acs-pci-adjunctive-devices/research-protocol
     July 01, 2010 - at baseline, detailed description of study outcomes, blinding of outcome assessors, intent-to-treat analysis … They have serious errors in design, analysis, or reporting; large amounts of missing information; or … Meta-Analysis in clinical trials. Controlled Clin Trials. 1986 ;7 :177-188. … Bias in Meta-Analysis Detected by a Simple, Graphical Test. BMJ 1997;315:629-34. … The TEP does not do analysis of any kind nor contribute to the writing of the report.

353. Menopausal Symptoms: Comparative Effectiveness Review of Therapies | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/menopause/research-protocol
     April 03, 2012 - Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. … Schwarzer G. meta: Meta-Analysis with R (version 1.6-1). … Subset: Systematic Review OR Publication Type: Meta-analysis OR (“meta-analysis” OR metaanalysis OR “ … Intention to treat analysis is performed. … Intention to treat analysis is lacking.

354. Fibromyalgia Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
     January 01, 2015 - Because fibromyalgia is largely a chronic condition in adults, we limited our analysis to studies of … A third type of study was a pooled analysis of individual patient data from several RCTs to report … Two RCTs with high risk of bias3,63 and one pooled IPD RCT analysis of four RCTs of duloxetine with … Nonoverlapping outcomes information was included for the pooled analysis in this review. … Systematic review and network meta-analysis of interventions for fibromyalgia: a protocol.

355. Prostate-Cancer-Test Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
     October 14, 2011 - : adjustment for potential confounders and intention-to-treat analysis Quality will be assessed … [Note: Irrelevant if only the data and analysis from the systematic review are used in this CER and … Matched Analysis For each individual matched study, the data can most likely be summarized in one … This software supports meta-analysis of both matched and unmatched data. … DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer.

356. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_executive.pdf
     December 01, 2011 - Data Synthesis and Analysis We qualitatively examined data from all identified studies. … Nine RCTs,6,23-25,28,29,33,40,42 an individual patient data meta- analysis,81,82 a pooled analysis,83 … Bias in meta- analysis detected by a simple, graphical test. … Adjunctive devices in primary or rescue PCI: a meta-analysis of randomized trials. … Sensitivity analysis: A ”what if ” analysis that helps determine the robustness of a study.

357. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
     May 01, 2006 - Number of studies reporting 6 15 3 Patients analyzed 2,205 3,293 659 Pooled relative risk of Hb Meta-analysis … increase >2 mg/dL (95% CI) not done1 3.42 (3.03, 3.86)2 3.36 (2.48, 4.56) Pooled event rates (range Meta-analysis … Results of this fixed-effects meta-analysis were compared with random-effects meta-analysis; results … , and quantitative analysis could not be performed for the 15 remaining studies. … Analysis of mortality in all 40 trials shows no overall benefit of darbepoetin or epoetin on survival

358. Topic Brief: Rehabilitation Options for Post-acute Care Diagnoses (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/rehab_options_pac_diagnoses_topic_brief.pdf
     October 28, 2020 - – 122 • Secondary health records database analysis – 127 KQ 2(c). … There was also very limited analysis of cost-of- care outcomes. … A Meta-Analysis. … Organised inpatient (stroke unit) care for stroke: network meta‐analysis. … Effectiveness of Stroke Early Supported Discharge: Analysis From a National Stroke Registry.

359. Geographic Variation in Carotid Endarterectomy and Carotid Stenting Among Medicare Beneficiaries, 2003-2006 | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/cardiology-health-outcomes/research
     July 28, 2010 - We limited the analysis to beneficiaries living in the United States who were aged 65 years or older. … Statistical Analysis We present categorical variables as frequencies with percentages. … Analysis and interpretation of data: Patel, Greiner, DiMartino, Schulman, Duncan, Matchar. … Statistical analysis: Greiner. Handled funding and supervision: Schulman, Matchar, Curtis. … Endarterectomy vs stenting for carotid artery stenosis: a systematic review and meta-analysis.

360. Evaluation of Dietary Protein Intake Requirements (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol.pdf
     May 01, 2023 - Current DRIs were established based on analysis of available nitrogen balance studies, which tend to … .24 When meta-analysis is not possible, we will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a narrative Summary of Findings table. … Meta-Analysis with R. 2015. 27. Higgins JP, Thompson SG, Deeks JJ, Altman DG.