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321. Evidence Summary Comparative Effectiveness Review 216 Telehealth for Acute and Chronic Care Consultations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-evidence-summary.pdf
     April 01, 2019 - Review To assess the effectiveness of telehealth consultations and explore supplemental decision analysis … traditional systematic review of the available research and explore how the addition of decision analysis … • Economic outcomes: Analysis of costs were available only in a few studies, and the results favored … The model specification and results of this analysis are included in Appendix I of the full report. … The decision analysis also highlighted the importance of perspective and the need for better information

322. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
     February 01, 2013 - Meta-Analysis or Individual Patient Data Analysis Across RCTs? … Analysis of Existing Data? Model? … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses … Meta-Analysis of RCTs If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide … Meta-Analysis of Observational Studies If a meta-analysis of RCTs is not feasible, the next most valid

323. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
     August 10, 2010 - A recent meta-analysis estimates prevalence for childhood ADHD world-wide to be 5.29% ( 95% CI 5.01 … A recent meta-analysis produced a pooled prevalence world wide of 2.5 % (95% CI 2.1-3.1).5 Over … The worldwide prevalence of ADHD: a systematic review and metaregression analysis. … Prevalence and correlates of adult attention- deficit hyperactivity disorder: meta-analysis. … The TEP does not do analysis of any kind nor contribute to the writing of the report. X.

324. Effects of Dietary Sodium and Potassium Intake on Chronic Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
     April 18, 2017 - Meta-analysis will be used to synthesize results across studies in random effect models. … Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. … Multivariate Dose-Response Meta-Analysis: The dosresmeta R Package. … Computational Statistics & Data Analysis. 2009;53(12):4157-67. 23. … Salt intake, stroke, and cardiovascular disease: meta- analysis of prospective studies.

325. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
     November 18, 2024 - inherently involve change and measurement changes over time will require careful consideration in analysis … , with interpretation of results) and quantitatively (meta-analysis) when appropriate. … If sufficient numbers of RCTs (≥10) are available, quantitative funnel plot analysis may be done. … The Volume of Breast Milk Intake in Infants and Young Children: A Systematic Review and Meta-Analysis … Advanced Dietary Analysis and Modeling: A Deep Dive into the National Cancer Institute Method.

326. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
     February 03, 2025 - Data Synthesis and Analysis We will synthesize the results of the review by health outcome. … We will consider performing meta-analysis for specific comparisons by outcomes when there is a signal … If a meta-analysis is not possible, we will present the results of an ESR along with an updated narrative … Breastfeeding and Type 2 Diabetes: Systematic Review and Meta- Analysis. … Breastfeeding and the risk of childhood cancer: a systematic review and dose-response meta-analysis.

327. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
     February 01, 2023 - Data Synthesis and Analysis We will synthesize the results of the review by health outcome. … We will consider performing meta-analysis for specific comparisons by outcomes when there is a signal … If a meta-analysis is not possible, we will present the results of an ESR along with an updated narrative … Breastfeeding and Type 2 Diabetes: Systematic Review and Meta- Analysis. … Breastfeeding and the risk of childhood cancer: a systematic review and dose-response meta-analysis.

328. Data Points 13: Use of Preoperative Breast MRI among older women with ductal carcinoma in situ and locally invasive breast cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-mri-utilization_research.pdf
     August 01, 2012 - Women who were diagnosed in Louisiana in 2005 were also excluded from this analysis because of the … MRI used in diag- nostic evaluation is excluded from this analysis. … Rates of MRI increased dramatically from 2002 to 2007; therefore, we limited the analysis of covariates … Use of Preoperative Breast MRI • # 13 • Data Points Surgery type: We used the Medicare Provider Analysis … Thus, our analysis underesti- mates the use of preoperative breast MRI and should not be used to assess

329. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The analysis, synthesis, and reporting of NRSIs also require special attention. … Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis. … Use of interrupted time series analysis in evaluating health care quality improvements. … Sensitivity Analysis in Observational Research: Introducing the E-Value. … The power of statistical tests for moderators in meta- analysis.

330. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The analysis, synthesis, and reporting of NRSIs also require special attention. … Breast Reconstruction After Mastectomy: A Systematic Review and Meta-Analysis. … Use of interrupted time series analysis in evaluating health care quality improvements. … Sensitivity Analysis in Observational Research: Introducing the E-Value. … The power of statistical tests for moderators in meta- analysis.

331. C-Diff-Infections-Surveillance-140925 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
     January 01, 2014 - , but not with strict intention-to-treat analysis. … A survival analysis. Ann Intern Med. 2007;147(4):224- 33.17638714 4. … (15.4% vs. 25.3%, P=0.005) and the per-protocol analysis (13.3% vs. 24.0%, P=0.004). … Weiss et 2012 Safety analysis A total of 728 adults 116 healthy N/A; tolerability, In this safety analysis … , but not with strict intention-to-treat analysis.

332. S131 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
     October 01, 2007 - Data Source of Empirical Analysis The study cohort was drawn from a population of seniors age 65 years … Cohort 5—Subgroup Analysis of Typical Trial-Eligible Subjects We restricted our final analysis to subjects … In the most restricted analysis (cohort 5), the unadjusted RR was 0.72. … An analysis of the exclusion criteria used in observational pharmacoepidemiological studies. … Subgroup analysis in randomized controlled trials: im- portance, indications, and interpretation.

333. Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
     November 01, 2020 - 3 RCTs) (fans) were effective for improving breathlessness compared with usual care or sham [Meta-analysis … • Opioids were not more effective than placebo (SOE: moderate) for improving breathlessness [Meta-analysis … between different doses or routes of administration of opioids for improving breathlessness [Meta-analysis

334. Colorectal-Surgery-Preparation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
     April 01, 2014 - We used both pairwise and network meta-analysis. … OMBP Versus No OMBP Eighteen RCTs and seven NRCSs contributed information to the main analysis. … These findings, in conjunction with the wide CrIs observed in the overall meta-analysis, support the … Using network meta-analysis we compared “OMBP with or without enema,” “enema,” and “no preparation” … We did not attempt a meta-analysis because of the substantial diversity in outcome definitions, and

335. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - They had serious errors in design, analysis, or reporting; large amounts of missing information; or … A descriptive analysis of minor depression. … Screening and case-finding instruments for depression: a meta-analysis. … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses

336. CER 216 Disposition of Comments Report: Telehealth for Acute and Chronic Care Consultations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-216-telehealth-disposition-comments.pdf
     April 24, 2019 - There are few large volume studies from w hich to inform the analysis and as such the authors w ere … TEP 4 General Comments The analysis of specialty consultation key f indings by setting (inpatient, … analysis. … The comment about lacking a probabilistic analysis is w ell-taken. … analysis; w e feel the one-w ay sensitivity analysis adequately characterized the large amount of

337. Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0594-131115.pdf
     March 13, 2013 - advanced genetic testing Summary: (comparative genomic hybridization [CGH], chromosomal microarray analysis … intellectual (DD/ID) disabilities and autism spectrum disorder (ASD) Intervention(s): Chromosomal microarray analysis

338. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
     February 01, 2013 - Meta-Analysis or Individual Patient Data Analysis Across RCTs? … Meta-Analysis or Individual Patient Data Analysis Across RCTs? … Multivariable analysis. … : Observational Meta-analysis of Observational Studies Yes META-ANALYSIS: OBSERVATIONAL STUDIES … Meta-Analysis of RCTs If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide

339. Evaluation of Dietary Protein Intake Requirements (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
     November 28, 2023 - Current DRIs were established based on analysis of available nitrogen balance studies, which tend to … .24 When meta-analysis is not possible, we will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a narrative Summary of Findings table. … Meta-Analysis with R. 2015. 27. Higgins JP, Thompson SG, Deeks JJ, Altman DG.

340. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
     April 01, 2020 - and Synthesis A random effects meta-analysis using the profile likelihood method was performed on … For meta-analyses of opioids versus placebo, the main analysis was stratified by opioid type. … Because the EERW design was seldom used before 2007, another stratified analysis on this factor was … The analysis was also performed on the likelihood of experiencing 50 percent or more improvement in … In the primary analysis we used the data as reported in the trials; as a sensitivity analysis, all