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281. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
     March 25, 2012 - Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. … Meta-analysis combining parallel and cross-over clinical trials. II: Binary outcomes. … Subset: Systematic Review OR Publication Type: Meta-analysis OR (“meta-analysis” OR metaanalysis OR … Intention to treat analysis is performed. … Intention to treat analysis is lacking.

282. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
     October 01, 2010 - We refer the investigators to the following citation: A survey of current problems in meta-analysis. … This is not reflected in the current analysis. 4-mm studies did not meet our inclusion criteria. … Although we are aware of those data, we did not include them in our analysis on rhythm control because … Since this analysis was conducted, an additional study has been released that would be relevant to … Jais 2008 has been added to the analysis.

283. Disposition of Comments for Treatment Strategies for Patients With Peripheral Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
     May 29, 2013 - The authors should include their analysis of the ability to conduct randomized surgical trials. … Methods Meet generally accepted practice of scientific analysis. Thank you. … J Vasc Surg 2009; 49:1217-1225) The study was performed using Markov analysis and concluded that … However the only RCT, the BASIL trial, is not fully represented by the authors of this analysis. … , but this subgroup analysis does not provide the level of evidence to make a key point and should

284. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
     December 01, 2009 - In our analysis of biopsy accuracy, we focused on measures that evaluate the extent of false-negative … Underestimation rates were combined using a random-effects meta-analysis. … , and for summary estimates calculated after assuming our analysis had overestimated the sensitivity … percent, but we present the results of this sensitivity analysis as a “worst case” scenario. … having cancer after a negative core-needle biopsy result1 Analysis Analysis Analysis overestimated

285. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
     July 01, 2012 - Meta-analysis of test performance when there is a "gold standard." … How to use a clinical decision analysis. B. … How to use a clinical decision analysis. A. Are the results of the study valid? … Endoscopic colorectal cancer screening: a cost-saving analysis. … Meta-analysis of test performance when there is a “gold standard.”

286. depression-pregnancy-postpartum-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
     March 29, 2013 - To determine the appropriateness of meta-analysis, the quality of the studies and the heterogeneity … Appropriate measures will be chosen based on the type of data for meta-analysis. … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539-58. … Methods for Meta-Analysis in Medical Research. … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

287. Nephropathy-Contrast-Induced Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
     October 01, 2015 - In the analysis of N-acetylcysteine plus intravenous saline compared with intravenous saline alone, … Our primary analysis showed that intravenous sodium bicarbonate did not produce a clinically important … However, in a sensitivity analysis, we found low SOE for a clinically important benefit in decreasing … Unfortunately, we had a limited ability to stratify the analysis according to baseline risk because … Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177-88. PMID: 3802833. 7.

288. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
     December 11, 2012 - Peer Reviewer #2 General Comment A future cost benefit analysis would also be helpful. … needed for future cost benefit analysis. … The detailed analysis of the papers is handicapped by excessive simplification. … The expert panel had no role in article selection or in the analysis. … Peer Reviewer #2 Discussion/ Conclusion Additionally a cost benefit analysis should be conducted

289. VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
     January 30, 2014 - We will examine the appropriateness of each study for inclusion in a meta-analysis. … The specific meta-analysis or meta- regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … I: A meta- analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. … the analysis, reporting, and claim of subgroup effects in randomized trials.

290. Menopause-Protocol-130612 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
     June 12, 2013 - Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. … Network meta-analysis also formally allows quantitative indirect comparisons. … Subset: Systematic Review OR Publication Type: Meta-analysis OR (“meta-analysis” OR metaanalysis OR … Intention to treat analysis is performed. … Intention to treat analysis is lacking.

291. CER 45 Self-Measured Blood Pressure Monitoring Comparative Effectiveness Surveillance Final 4.7.16 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure-surveillance-160412.pdf
     October 08, 2025 - ramipril"in" elderly"hypertensive"patients:"pooled"individual"data"analysis"of"two"randomized,"double … $Meta"analysis$of$a$small$number$of$studies$for$the$net$ changes$in$24"hour$ambulatory$SBP$and$DBP$at … $Both$experts$ recommended$ examining$evidence$ from$a$new$IPD$meta" analysis 1 $currently$being … $This$meta" analysis$compared$ patients$who$self" monitor$BP$to$patients$ receiving$usual$care. … $Both$experts$ recommended$reviewing$ the$IPD$meta"analysis 1 $ for$new$evidence.

292. Outcome Definition and Measurement in Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
     January 01, 2013 - Study Design and Analysis (1 of 2) Study Design and Analysis (1 of 2) Avoidance of Bias in Study … Sensitivity analysis This type of analysis determines how varying definitions of study outcome will affect … Study Design and Analysis (2 of 2) Study Design and Analysis (2 of 2) Study Period and Length of … Use appropriate analytic methods suitable to the outcome measure and sensitivity analysis to address … Analysis The proposed analytical methods should correspond to the nature of the outcome measure (e.g.

293. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - Meta-analysis from the Antithrombotic Trialists’ Collaboration has demonstrated the benefit of at least … showing no difference in amputation-free survival or mortality at 2 years, the as-treated analysis … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses

294. Telehealth for Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
     June 21, 2021 - To determine whether meta-analysis could be meaningfully performed, we will consider the risk of bias … For this analysis, rural is broadly defined by any commonly used or endorsed definition. … Trends Analysis: Pre & Post School Closures – April 29, 2020. 2020. https://www.portlandoregon.gov/police … https://www1.nyc.gov/site/nypd/stats/reports-analysis/domestic-violence.page. … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

295. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - The statistical methods are standard for this type of analysis. … We used the data from the placebo controlled trials in our network meta-analysis. … We conducted a mixed treatment analysis for akathisia (KQ4). … One can also use the mixed treatment analysis presented in Figure 31. … One can also use the mixed treatment analysis presented in Figure 31.

296. antibiotics-respiratory-infection-protocol-140922 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
     September 22, 2014 - In consultation with our statistician, we will consider a network analysis to make comparisons across … When meta-analysis cannot be performed, the data will be summarized qualitatively, grouping studies … In: Shojania KG MK, Wachter RM, Owens DK, ed Closing the Quality Gap: A Critical Analysis of Quality … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539--58. 20. … Methods for Meta-Analysis in Medical Research: John Wiley & Sons, Inc.; 2000. 21.

297. Liver-Cancer-Therapy Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
     May 01, 2013 - that adjusts for potential confounders and intention-to-treat analysis. … In addition, for RCTs, intention-to-treat analysis is used. … Intention-to-treat analysis is done for RCTs. … For RCTs, intention-to-treat analysis is lacking. … TACE combined with PEI versus TACE alone in the treatment of HCC: a meta-analysis.

298. Gout Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
     March 01, 2016 - the following strategy for data synthesis/analysis: 1. … in prior SRs Included in analysis (N=15) KQ4 (N=26) Included in analysis (N=26) KQ 5 (N=3 … Moxibustion for rheumatic conditions: A systematic review and meta-analysis. … Increased risk of skin reactions with gout medications: An analysis of va databases. … Serum urate levels and gout flares: analysis from managed care data.

299. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Text of ES edited to clarify that RCTs only included in meta-analysis. … A forest plot is shown as we have done meta- analysis of the NRCS. … We preferred not to combine RCTs and NRCS in the meta-analysis. … Text edited to reflect that this was an intention to treat analysis. … "Two studies were excluded from our meta-analysis.

300. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Text of ES edited to clarify that RCTs only included in meta-analysis. … A forest plot is shown as we have done meta- analysis of the NRCS. … We preferred not to combine RCTs and NRCS in the meta-analysis. … Text edited to reflect that this was an intention to treat analysis. … "Two studies were excluded from our meta-analysis.