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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-pregnancy-postpartum_research-protocol.pdf
    March 29, 2013 - To determine the appropriateness of meta-analysis, the quality of the studies and the heterogeneity … Appropriate measures will be chosen based on the type of data for meta-analysis. … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15;21(11):1539-58. … Methods for Meta-Analysis in Medical Research. … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have
  2. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
    December 01, 2009 - In our analysis of biopsy accuracy, we focused on measures that evaluate the extent of false-negative … Underestimation rates were combined using a random-effects meta-analysis. … , and for summary estimates calculated after assuming our analysis had overestimated the sensitivity … percent, but we present the results of this sensitivity analysis as a “worst case” scenario. … having cancer after a negative core-needle biopsy result1 Analysis Analysis Analysis overestimated
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
    October 01, 2015 - In the analysis of N-acetylcysteine plus intravenous saline compared with intravenous saline alone, … Our primary analysis showed that intravenous sodium bicarbonate did not produce a clinically important … However, in a sensitivity analysis, we found low SOE for a clinically important benefit in decreasing … Unfortunately, we had a limited ability to stratify the analysis according to baseline risk because … Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177-88. PMID: 3802833. 7.
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
    October 01, 2010 - We refer the investigators to the following citation: A survey of current problems in meta-analysis. … This is not reflected in the current analysis. 4-mm studies did not meet our inclusion criteria. … Although we are aware of those data, we did not include them in our analysis on rhythm control because … Since this analysis was conducted, an additional study has been released that would be relevant to … Jais 2008 has been added to the analysis.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-women-protocol.pdf
    June 21, 2021 - To determine whether meta-analysis could be meaningfully performed, we will consider the risk of bias … For this analysis, rural is broadly defined by any commonly used or endorsed definition. … Trends Analysis: Pre & Post School Closures – April 29, 2020. 2020. https://www.portlandoregon.gov/police … https://www1.nyc.gov/site/nypd/stats/reports-analysis/domestic-violence.page. … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_disposition-comments.pdf
    May 29, 2013 - The authors should include their analysis of the ability to conduct randomized surgical trials. … Methods Meet generally accepted practice of scientific analysis. Thank you. … J Vasc Surg 2009; 49:1217-1225) The study was performed using Markov analysis and concluded that … However the only RCT, the BASIL trial, is not fully represented by the authors of this analysis. … , but this subgroup analysis does not provide the level of evidence to make a key point and should
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
    December 11, 2012 - Peer Reviewer #2 General Comment A future cost benefit analysis would also be helpful. … needed for future cost benefit analysis. … The detailed analysis of the papers is handicapped by excessive simplification. … The expert panel had no role in article selection or in the analysis. … Peer Reviewer #2 Discussion/ Conclusion Additionally a cost benefit analysis should be conducted
  8. effectivehealthcare.ahrq.gov/sites/default/files/bar-cohen-ii_eccs2012.pdf
    January 01, 2012 - of 2) • The 2012 Progress Report of the  National Breast Cancer  Coalition  included   an analysis … o Twenty-­‐eight newspaper articles and seven magazine pieces were included  in the  analysis. … • The analysis  showed that: o 31% of the  stories  were  on prevention  and  risk. o
  9. effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
    January 01, 2013 - Study Design and Analysis (1 of 2) Study Design and Analysis (1 of 2) Avoidance of Bias in Study … Sensitivity analysis This type of analysis determines how varying definitions of study outcome will affect … Study Design and Analysis (2 of 2) Study Design and Analysis (2 of 2) Study Period and Length of … Use appropriate analytic methods suitable to the outcome measure and sensitivity analysis to address … Analysis The proposed analytical methods should correspond to the nature of the outcome measure (e.g.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis. … Network meta-analysis also formally allows quantitative indirect comparisons. … Subset: Systematic Review OR Publication Type: Meta-analysis OR (“meta-analysis” OR metaanalysis OR … Intention to treat analysis is performed. … Intention to treat analysis is lacking.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
    June 24, 2014 - gout Intervention(s): Clinical criteria for diagnosis of acute gouty arthropathy and synovial fluid analysis … criteria only in the diagnosis of acute gouty from Nominator: arthropathy instead of synovial fluid analysis … often based primarily on clinical signs and symptoms, and usually without the use of synovial fluid analysis
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
    July 01, 2022 - Meta-Analysis Evidence Tables ....................................................................... … / or systematic review/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review … An Updated Systematic Review and Meta-analysis of Duloxetine for Knee Osteoarthritis Pain. … A Meta-Analysis of Randomized Control Trials. … Efficacy and safety of pregabalin for chronic neuropathic pain: a meta-analysis.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - If meta-analysis is deemed appropriate, we plan to use the profile likelihood random effect method … to combine direct comparisons between treatments if the number of studies included in the analysis is … A likelihood approach to meta-analysis with random effects. … Explaining heterogeneity in meta-analysis: a comparison of methods. … Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
    January 30, 2014 - We will examine the appropriateness of each study for inclusion in a meta-analysis. … The specific meta-analysis or meta- regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … I: A meta- analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. … the analysis, reporting, and claim of subgroup effects in randomized trials.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
    January 31, 2013 - Meta-analysis from the Antithrombotic Trialists’ Collaboration has demonstrated the benefit of at least … showing no difference in amputation-free survival or mortality at 2 years, the as-treated analysis … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tw] OR "meta-analyses
  16. effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
    January 01, 2013 - Consider potential reductions in the number of recruited patients available for analysis. … Potential reductions in the number of recruited patients available for analysis (e.g., due to loss to … less overlap in propensity score distributions across cohorts), many patients will drop out of the analysis … Examples include Stata, Confidence Interval Analysis, and Power Analysis and Sample Size (PASS). … include: The investigators anticipate strong confounding that will eliminate many patients from the analysis
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
    November 27, 2012 - The statistical methods are standard for this type of analysis. … We used the data from the placebo controlled trials in our network meta-analysis. … We conducted a mixed treatment analysis for akathisia (KQ4). … One can also use the mixed treatment analysis presented in Figure 31. … One can also use the mixed treatment analysis presented in Figure 31.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
    September 22, 2014 - In consultation with our statistician, we will consider a network analysis to make comparisons across … When meta-analysis cannot be performed, the data will be summarized qualitatively, grouping studies … In: Shojania KG MK, Wachter RM, Owens DK, ed Closing the Quality Gap: A Critical Analysis of Quality … Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539--58. 20. … Methods for Meta-Analysis in Medical Research: John Wiley & Sons, Inc.; 2000. 21.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
    April 03, 2014 - Data fields to be extracted will be determined based upon the proposed summary analysis. … The risk of bias of the individual RCTs that comprise each pooled analysis will be assessed per the … Because of the high probability of placebo effects in fibromyalgia treatments, if subgroup analysis … We will conduct a brief qualitative sensitivity analysis of the excluded observational literature for … Systematic review and network meta-analysis of interventions for fibromyalgia: a protocol.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure-surveillance-160412.pdf
    May 29, 2025 - ramipril"in" elderly"hypertensive"patients:"pooled"individual"data"analysis"of"two"randomized,"double … $Meta"analysis$of$a$small$number$of$studies$for$the$net$ changes$in$24"hour$ambulatory$SBP$and$DBP$at … $Both$experts$ recommended$ examining$evidence$ from$a$new$IPD$meta" analysis 1 $currently$being … $This$meta" analysis$compared$ patients$who$self" monitor$BP$to$patients$ receiving$usual$care. … $Both$experts$ recommended$reviewing$ the$IPD$meta"analysis 1 $ for$new$evidence.

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