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2261. Recurrent Nephrolithiasis in Adults: A Comparative Effectiveness Review of Preventive Medical Strategies | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/kidney-stone-prevention/research-protocol
      June 15, 2011 - Testing may include an analysis of stone composition and biochemical evaluations of blood (e.g., calcium … Where data allow, the proposed systematic review and meta-analysis will comprehensively address all these … The ratings may be used to conduct sensitivity analysis of results, such as by including and excluding … Meta-analysis of randomized trials for medical prevention of calcium oxalate nephrolithiasis. … TEP members will not perform analysis of any kind, or contribute to the writing of the report.

2262. S16 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
      October 01, 2007 - Individual patient meta-analysis is more powerful for this purpose, and has been used with success in … An analysis of 7 primary prevention trials suggests that the TABLE 4. … Subgroup analysis of trials indicates that the benefits are much greater in asymptomatic men than in … NIH Program on Clinical Research Policy and Analysis and Coordination. … Subgroup analysis in randomized controlled trials: im- portance, indications, and interpretation.

2263. Colon-Cancer-Gene-Profiling Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
      March 13, 2012 - Was a reclassification analysis performed with risk stratification using GEP when compared with that … (It is suggested that samples from at least two-thirds of the patients must be available for analysis … o Type(s) of tissue used (e.g., fresh tissue) o Time for analysis (turnaround time) • Inclusion and … • Was MSI (MMR) status considered in the overall analysis? o If so, how? … • Was the GEP performed (analysis, calculation, interpretation) as described in initial studies for

2264. Untitled (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
      October 12, 2015 - They had serious errors in design, analysis, or reporting; large amounts of missing information; or … We will then determine the feasibility of completing a quantitative synthesis (i.e., meta- analysis, … decision analysis, or simulation model). … to which such an analysis will provide additional insight into the key questions based 21! … Infertility and the risk of adverse pregnancy outcomes: a systematic review and meta-analysis.

2265. Antipsychotics-Children-Surveillance-150120 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
      October 01, 2014 - Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. … SRC Literature Analysis: • The original CER concluded that SGAs were favored over FGAs for symptom … We performed meta-analysis for primary and secondary outcomes, when possible. … RESULTS: Planned interim analysis for the primary end-point in the RCT resulted in early termination … Per-protocol analysis was significant (p=0.02).

2266. A Bayesian Missing Data Framework for Multiple Continuous Outcome Mixed Treatment Comparisons (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
      January 01, 2013 - Our data analysis also has some limitations. … Bayesian approaches to random-effects meta-analysis: a comparative study. … Accounting for correlation in network meta- analysis with multi-arm trials. … Bayesian Analysis 1. 2006;1:651-706. 25. Salanti G, Ades AE, Ioannidis JP. … Meta- analysis of mixed treatment comparisons at multiple follow-up times.

2267. Progestogens-Preterm-Birth Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
      September 01, 2012 - Meta-Analysis We conducted a Bayesian meta-analysis to provide aggregate estimates of the effectiveness … Interpretation of Meta-Analysis In the Results section of the full report, we report the findings from … meta-analysis as odds ratios (OR) from Bayesian models. … The relationship between number of injections and outcome was examined in a single database analysis … We calculated meta-analysis estimates by using RCTs grouped by progestogen formulation (17OHP, oral,

2268. Evidence-based Practice Center Systematic Review Protocol: Depression in Children: Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
      August 06, 2018 - A systemic review and meta-analysis of the effectiveness of interpersonal psychotherapy for adolescents … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report … ”[pt] OR “meta- analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] … ”[pt] OR “meta- analysis”[ti] OR “systematic literature review”[ti] OR “this systematic review”[tw] … 2 #34 Search (#31 NOT (#19 or #21)) Sort by: Author Filters: Meta-Analysis; Systematic Reviews 9

2269. Obesity (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
      June 01, 2014 - intragastric balloons coming to the U.S. market might need to undergo a formal national coverage analysis … phentermine-topiramate, respectively, compared to 2.1% in the placebo group (p<0.0001); in the ITT-LOCF analysis

2270. Radiotherapy Treatments for Head and Neck Cancer: Update | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/head-neck-cancer-update/research-protocol
      February 04, 2014 - If an EPC performed a meta-analysis, then it may also consider whether the CI crossed a threshold for … If meta-analysis is infeasible or inappropriate, the EPC may consider the narrowness of the range of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have … In addition, intention-to-treat analysis is used for RCTs. … Intention-to-treat analysis has been done for RCTs.

2271. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
      February 01, 2013 - One meta-analysis published in 2002 included 10 trials, while another published in 2004 included only … Our analysis of this example showed that included study designs varied among reviews. … A meta-analysis incorporating prior knowledge of anti-fracture efficacy in women. … Meta-analysis of alendronate for the treatment of postmenopausal women. … University of Pennsylvania Meta-analysis Blinding Study Group.

2272. Chronic-Cough Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
      March 01, 2014 - We supplemented the meta-analysis of direct comparisons with a mixed treatment meta-analysis that incorporated … standard random-effects models used in the meta-analysis of effect sizes. … This analysis included 11 studies and 700 patients. … We performed a similar meta-analysis for cough frequency, including 7 studies and 396 patients. … bTotal number of studies/patients from mixed treatment meta-analysis. 13 agents.

2273. Enhanced Functionality for the Distributed Research Network Pilot (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-expansion_research.pdf
      April 01, 2012 - sets in return • Investigate the technical requirements needed to perform distributed multivariate analysis … There is tremendous value in providing analysis tools for patient-level data sets that would not require

2274. Disposition of Comments for Technical Brief 22 Environmental Cleaning for the Prevention of Healthcare-Associated Infections (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/healthcare-infections_disposition-comments.pdf
      August 10, 2015 - for Implementing Cleaning and Monitoring Modalities (guiding question 2) is followed by a detailed analysis … Peer Reviewer 2 Clarity and Usability I prefer the structure of analysis suggested by McDonald and

2275. Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
      March 01, 2013 - Among 83 RCTs, 65 studies are included for our analysis. … For Bayesian analysis, we report the posterior median values. … However, there are some limitations in the frequentist analysis. … analysis (in the UI data analysis, σ for continence and discontinuation outcomes are close to zero) … Bayesian Methods for Data Analysis, 3rd edition.

2276. Cad-Pci-Bypass Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
      May 01, 2013 - Grafting for Coronary Artery Disease, was released in October 2007.1An individual patient data meta-analysis … Two of three experts responded that the broad conclusion of the 2009 individual patient meta- analysis … surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis … A survival analysis. Ann Intern Med. 2007 Aug 21;147(4):224-33. PMID 17638714. 5. … intervention versus coronary artery bypass graft surgery in left main coronary artery disease: a meta-analysis

2277. Nppv-Respiratory-Failure Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
      July 01, 2012 - We then determined the feasibility of completing a quantitative synthesis (i.e., meta-analysis). … quantitatively using the Comprehensive Meta-Analysis software (Version 2; Biostat, Englewood, NJ). … Mortality is a dichotomous outcome and was fitted using multiple logistic regression analysis. … Meta-analysis: noninvasive ventilation in acute cardiogenic pulmonary edema. … Meta-analysis of multitreatment studies. Med Decis Making. 1998;18(1):37-43. PMID: 9456207. 53.

2278. Methods Research Report: Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test of an Interactive Web-Based Presentation and Discussion of Evidence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/linking-evidence-reviews-methods_0.pdf
      October 01, 2018 - A detailed analysis of the overlap and nonoverlap between reviews and the reasons for data congruence

2279. Diagnosis and Treatment of Clinical Alzheimer’s-Type Dementia: Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
      April 01, 2020 - interval between imaging or CSF collection and autopsy, methods of image acquisition or CSF assay and analysis

2280. Registries for Evaluating Patient Outcomes: A User's Guide, 3rd Edition | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/registries-guide-3rd-edition/overview