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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
    February 01, 2012 - Cost–Benefit Analysis A quality-adjusted cost–benefit analysis is recommended, comparing the incremental … trials to allow meta- analysis, but patient-level meta-analysis would be required to evaluate the differential … Patient-Level Meta-analysis Standard meta-analysis of existing studies is not feasible due to the large … analysis and performing a unitary analysis. … into a regression analysis and performing a unitary analysis.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
    September 28, 2015 - General This report describes the process and findings of an extensive systematic review and meta-analysis … For example, in the results section for the ethnicity subgroup analysis in the Executive summary we … We have added the findings for inconsistency for the network meta-analysis to the results section, “ … A consistency analysis was performed for the HbA1c analysis and it was found that only two quadratic … We did run a sensitivity analysis where we thinned the MCMC to every 10th iteration.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_policymaker.pdf
    June 01, 2016 - N Finding SOE BETA-BLOCKERS Propranolol vs. observation or placebo Improvement in IH Network meta-analysis … propranolol arm (fewer than 15% of children) ��� Propranolol vs. steroids Improvement in IH Network meta-analysis … Equivalent response ��� Topical timolol vs. placebo or observation Improvement in IH Network meta-analysis … more effective ��� STEROIDS Oral steroids vs. observation or placebo Improvement in IH Network meta-analysis … observation or placebo Improvement in IH Network meta-analysis N/A Intralesional steroids more effective
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
    January 01, 2011 - Exclusion rate from the analysis 6±2 4. Exclusion rate from the analysis 6±3 5. … Sampling bias is addressed in the analysis 5±3 5. … Statistical analysis 5±1 Assessment of temporality*** 5±2 10. … A meta-analysis of three methods of treatment. … Meta-analysis of anterior veneer restorations in clinical studies.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
    March 14, 2024 - A recent meta- analysis of 30 randomized controlled trials of psychosocial interventions compared with … We will determine whether meta-analysis is appropriate (i.e., more than two studies address the same … If a meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report
  6. effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
    February 24, 2016 - Can be part of a separate key question or just part of this analysis. … For this reason, CV and metabolic endpoints should be considered in the analysis. … Page 106: Meta Analysis for Radical vs. … Heterogeneity in study design and reported outcomes prevent meta-analysis. … Results should also be labeled as to what analysis they were derived from.
  7. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
    December 04, 2015 - Meta<analysis! … Meta<analysis! … versus usual care) through standard meta-analysis, a network meta-analysis allows for simultaneous … Analysis!of!Subgroups!! … to network meta-analysis.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
    May 01, 2017 - A network meta-analysis of the mean duration of middle ear effusion is presented in the full report. … After excluding 4 studies, 7 studies were included in the network meta-analysis. … Key Question 5 Seven RCTs were included in a network meta-analysis of the comparative effectiveness … Grommets in otitis media with effusion: an individual patient data meta-analysis. … Meta analysis of tympanostomy tube sequelae. Otolaryngol Head Neck Surg. 2001 Apr;124(4):374- 80.
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    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
    January 01, 2009 - A sub-analysis of the KIMS database. Growth Horm IGF Res 2005;15:349-359. … Sensitivity Analyses: A ‘what if’ analysis that helps determine the robustness of a study. … Statistical Heterogeneity: Variability in the observed effects among studies in a meta-analysis. … Analysis of cystic fibrosis referrals for lung transplantation. … Longitudinal analysis of pulmonary function decline in patients with cystic fibrosis.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
    May 01, 2022 - (meta-analysis performed if new evidence was large relative to the studies in the original meta-analysis … ); consistency in findings between the new studies and the original meta-analysis (meta-analysis performed … and a trial sequential analysis. … Acupuncture for acute low back pain: a systematic review and meta-analysis. … Effect of preemptive acetaminophen on opioid consumption: a meta-analysis.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
    April 01, 2022 - (meta-analysis performed if new evidence was large relative to the studies in the original meta-analysis … ); consistency in findings between the new studies and the original meta-analysis (meta-analysis performed … performed if the strength of evidence based on the original meta- analysis was low or insufficient and … Opioids for chronic low back pain management: a Bayesian network meta- analysis. … A Systematic Review and Meta-Analysis.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - screening (analysis 2). … Only data from analysis 1 was used in this review. … Patients with inflammatory conditions not included in our analysis. … 4.4 Were all patients included in the analysis? … Another 1,498 that were enrolled had samples reserved for future analysis and were not used in the analysis
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
    January 01, 2025 - screening (analysis 2). … Only data from analysis 1 was used in this review. … Patients with inflammatory conditions not included in our analysis. … 4.4 Were all patients included in the analysis? … Another 1,498 that were enrolled had samples reserved for future analysis and were not used in the analysis
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
    September 01, 2010 - Because of the recent high quality meta-analysis focused on treatment options after surgical resection … A sensitivity analysis will include study populations with all levels of disease severity. … A sensitivity analysis will include study populations with all levels of disease severity. … The TEP does not do analysis of any kind nor contribute to the writing of the report. X. … Sensitivity analysis for KQ3 will include inflammatory bowel disease not specified.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
    November 24, 2014 - (i.e., meta-analysis) of the data from those studies. … We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Antidepressant drug effects and depression severity: a patient-level meta-analysis. … Psychotherapy for depression in adults: a meta-analysis of comparative outcome studies. … Brief psychotherapy for depression: a systematic review and meta-analysis.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
    May 08, 2023 - Last year of data used in analysis 2015 or later for original research 6 Study Parameter … We will not conduct a meta-analysis. … Making health care safer: a critical analysis of patient safety practices. … Making Healthcare Safer III: A Critical Analysis of Existing and Emerging Patient Safety Practices. … We will not conduct a meta-analysis.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
    June 01, 2016 - In a network meta-analysis, the largest mean estimate of expected clearance was for oral propranolol … The efficacy of steroids may be higher than reflected in this analysis. … placebo or observation Improvement in IH Network meta-analysis 3 additional studies (188 subjects … observation or placebo Improvement in IH Network meta-analysis Oral steroids more effective … For these reasons, efficacy may be higher than that reflected in this analysis.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
    February 01, 2015 - Random-effects meta-analysis of inconsistent effects: a time for change. … Random-effects model for meta-analysis of clinical trials: an update. … How do you use existing risk of bias in a modified or new analysis? … studies to adding the new studies and rerunning the existing analysis. … Scenario 3 Use review with new or modified analysis Will do a new analysis if the existing analysis
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - An analysis of claims from one large insurer demonstrated that the most common indication for colorectal … We argue that the retracted study should not be included at all in a meta-analysis. … The determination on the appropriateness of meta-analysis will be made before any data analysis; we … will not base the decision to perform meta-analysis on statistical criteria for heterogeneity. … Network meta-analysis for indirect treatment comparisons. Stat Med 2002 Aug 30;21:2313-24.
  20. effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
    March 24, 2017 - , without attempting to incorporate the new studies into the meta-analysis. … When analyzing newer studies to add to the analysis of Griebeler et al, it appears that these newer … studies were not added to the meta- analysis, but instead taken individually and directly compared … We had made this decision to be consistent with Griebeler et al. meta-analysis that we were using … We have conducted a new meta- analysis in this section, including unpublished trials.

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