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181. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
     February 07, 2025 - Data Synthesis: We will summarize the evidence qualitatively and quantitatively (e.g., meta- analysis … , network meta-analysis) when possible. … To assess whether pairwise meta-analysis will be appropriate, we will consider population factors such … In considering network meta-analysis, we will evaluate how these factors are distributed across direct … Estimating interactions and subgroup‐ specific treatment effects in meta‐analysis without aggregation

182. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Long-term clinical outcomes SRC Literature Analysis: •! … Short-term mortality SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •! … Other SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •!

183. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - Long-term clinical outcomes SRC Literature Analysis: •! … Short-term mortality SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •! … Other SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •!

184. Appendix A - The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease-appendix-a.pdf
     August 31, 2023 - " or placebo* or nocebo* or random* or "prospective study" or "prospective survey" or "prospective analysis … " or prospectiv* or "quasi experimental study" or "quasi experimental analysis" or "quasiexperimental … study" or "quasiexperimental analysis" or "case control study" or "case base study" or "case referrent

185. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-failure-rescue-protocol-amendment.pdf
     September 19, 2023 - We will not conduct a meta- analysis. … Analysis of Subgroups or Subsets We will perform a sub-group analysis for pediatric patients and adults … Effects of rapid response systems on clinical outcomes: systematic review and meta-analysis. … Rapid Response Teams: A Systematic Review and Meta-analysis. … Rapid response systems: a systematic review and meta-analysis.

186. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
     May 02, 2025 - Data Synthesis: We will summarize the evidence qualitatively and quantitatively (e.g., meta- analysis … , network meta-analysis) when possible. … To assess whether pairwise meta-analysis will be appropriate, we will consider population factors such … In considering network meta-analysis, we will evaluate how these factors are distributed across direct … Estimating interactions and subgroup‐ specific treatment effects in meta‐analysis without aggregation

187. Traumatic Brain Injury and Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
     January 30, 2014 - Factor"analysis"of"persistent" postconcussive"symptoms"within"a"military"sample"with"blast"exposure. … DK2" " $ Current$Literature$Analysis:$ •" No"studies"were"identified. … " $ Current$Literature$Analysis:$ •" No"studies"were"identified. … " " " " " " " DK5" " Original(Systematic(Review(Conclusions(and(Literature(Analysis( … $DESIGN:$Secondary$data$ analysis.$SETTING:$Acute$inpatient$rehabilitation$facilities.

188. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
     December 07, 2024 - Analysis Type 5. Method for Handling Missing Data 6. Statistical Analysis Method 7. … Adjusted Variables in Statistical Analysis 8. Cluster Randomized Trial 9. … Analysis Type 6. Statistical Analysis Method 7. Adjusted Variables in Statistical Analysis 8. … Analysis Type 2. Assessment Point Category 3. Assessment Point 4. Outcome Measure 5. … plan that was finalized before unblinded outcome data were available for analysis?

189. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
     February 05, 2025 - , network meta- analysis). … Symptoms of depression and anxiety in youth with type 1 diabetes: a systematic review and meta-analysis … Mindfulness-based interventions for youth with anxiety: a systematic review and meta-analysis. … An updated meta- analysis of randomised controlled trials. … Network meta-analysis of multicomponent interventions.

190. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
     September 25, 2024 - , network meta- analysis). … Symptoms of depression and anxiety in youth with type 1 diabetes: a systematic review and meta-analysis … Mindfulness-based interventions for youth with anxiety: a systematic review and meta-analysis. … An updated meta- analysis of randomised controlled trials. … Network meta-analysis of multicomponent interventions.

191. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - Thank you for pointing us to the meta-analysis by Holmes et al. … The individual patient data meta-analysis by Brar et al. … We realize that this analysis also assumes a dominant genetic model. … In addition, although no meta-analysis is done, it looks to the naked eye as if a meta-analysis would … An analysis to determine the robustness of cutoff selection was performed in a meta‐ analysis of patient‐level

192. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
     September 03, 2019 - Could the authors please add more language to the methods section on the use of meta analysis. … Decisions on what to pool in a meta-analysis can often be subjective. … We considered conducting a meta-analysis of length of stay in hospital. … Meta-analysis of median values is generally not acceptable and we determined that transformation of … It’s unclear why only three of the RCTs were included in the meta-analysis.

193. Infantile-Hemangioma Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
     January 01, 2016 - Excluded studies had no further analysis. … included 18 studies in a network meta-analysis. … The network meta- analysis provided additional data. … Observation or Placebo Network meta-analysis Improvement in IH Moderate In network meta-analysis oral … Observation or Placebo Network meta-analysis Improvement in IH Low In network meta-analysis intralesional

194. Suicidal-Thoughts-Young-People-Amendement-May-2025 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
     January 01, 2025 - A recent meta- analysis of 30 randomized controlled trials of psychosocial interventions compared with … We will determine whether meta-analysis is appropriate (i.e., more than two studies address the same … If a meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report

195. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - Also, we have suggested some approaches for reporting the results of such an analysis. … Here, one might consider using the IV in a secondary or sensitivity analysis. … Analysis using instrumental variables. JAMA 1994;272:859-866. 26. … IV as a Secondary Analysis. … may be useful as a confirmatory or secondary analysis.

196. Ced -Appendix-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
     October 08, 2025 - We are concerned about the approach to analysis and recommendations through a literature search involving … not included and we believe transparency into this decision would provide important context to this analysis … CED should not substitute CMS analysis of clinical evidence and conclusions for decisions delegated to … Flexibility in determining the most appropriate study design, data, outcomes, and analysis methods is … not included and we believe transparency into this decision would provide important context to this analysis

197. Meditation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
     October 17, 2012 - • Was intent-to-treat analysis used? … Mindfulness-based stress reduction and cancer: a meta-analysis. Psychooncology. … Use and avoidance of continuity corrections in meta-analysis of sparse data. … This is not a statistical analysis, but rather a way to visually display the data. … We will also conduct a sensitivity analysis of this analysis by reversing the prioritization order

198. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
     July 01, 2012 - A meta-analysis could provide more precise estimates of outcome probabilities. … A meta-analysis of randomized control trials. Circulation 1990;82(4):1106-16. 24. … Anemia and mortality in heart failure patients: a systematic review and meta-analysis. … Decision curve analysis: a novel method for evaluating prediction models. … Meta- analysis of summary survival curve data.

199. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - We also repeated our main analysis excluding preprint studies. … Was appropriate statistical analysis used? 23 Table B-3. … Methods to estimate the between-study variance and its uncertainty in meta-analysis. … Introduction to meta-analysis. Chichester, U.K.: John Wiley & Sons; 2009. 22. … A general parametric approach to the meta‐analysis of randomized clinical trials.

200. The Effectiveness of Indoor Allergen Reduction and the Role of Bronchial Thermoplasty in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nonpharmacologic-treatment_research-protocol.pdf
     October 04, 2016 - Decisions about whether meta-analysis is appropriate will depend on the judged clinical homogeneity … using the Hartung-Knapp method.18,19 Meta-regression and subgroup analysis will be used to explore … A refined method for the meta-analysis of controlled clinical trials with binary outcome. … Random-effects meta-analysis of inconsistent effects: a time for change. … Technical Experts do not do analysis of any kind nor do they contribute to writing the report.