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1721. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
      March 01, 2012 - Peer Reviewer #2 Executive Summary “Many trials were excluded from the subgroup analysis because … Although, in the subgroup analysis, the results were less likely to show significance. … Further, different types of epilepsy are lumped together in the analysis. … They did not conduct a multivariate analysis in this study. … We followed a systematic and a priori format in our data analysis that we not like to alter.

1722. Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
      April 01, 2017 - In this trial, patients younger than age 40 were excluded after 2001 because of an early analysis that … Predictors of local recurrence following accelerated partial breast irradiation: a pooled analysis. … A pooled analysis of outcomes for 300 patients with DCIS treated with APBI. … A retrospective analysis of patients treated at the European Institute of Oncology. … Accelerated partial breast irradiation with IMRT: new technical approach and interim analysis of acute

1723. Treatment Resistant Depression Surveillance FINAL (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
      April 01, 2016 - Current Literature Analysis: • We identified a RCT comparing unilateral brief pulse to ultra-brief … Current Literature Analysis: • We identified a small phase II RCT examining individuals with MDD who … Current Literature Analysis: • No studies were identified. … Conclusions from Original Systematic Findings and Assessment from prior Literature Analysis (March 2016 … RESULTS: Linear mixed-effects modeling analysis revealed that ECT was significantly more effective

1724. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
      December 14, 2010 - A minimum of three studies is required for meta-analysis. … For trials that are judged sufficiently clinically similar to warrant meta-analysis, we will estimate … For groups of trials not judged sufficiently clinically similar to support meta- analysis, we will perform … In both meta-analysis and narrative descriptions, diabetes related outcomes (e.g., blood glucose) will … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

1725. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
      June 23, 2011 - Review This review is part of the Closing the Quality Gap series, which aims to provide critical analysis … o Intention-to-treat analysis. … Heterogeneity will be assessed, based on analysis of the data abstracted on intervention design and … Payment reform: analysis of models and performance measurement implications. … Comment on the potential weaknesses caused by, or inherent in, the indirect analysis.

1726. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
      November 20, 2014 - Peer Reviewer 4 Methods Data analysis: The statistical analysis methods are generally sound. 1. … The majority of the analysis focused on the comparative analysis of the effectiveness of the imaging … Mistakes like these make the analysis in this paper very questionable. … We pooled the results from both studies in a random-effects meta-analysis. … It’s a meta-analysis. The question is not well answered. f.