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161. EHC Protocol: Recurrent Nephrolithiasis in Adults and Children: Comparative Effectiveness of Preventive Medical Strategies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
     September 24, 2024 - (when available), serum chemistries, and urine analysis for first-time stone formers, with 24-hour … have a preference for this workup.3 Some authorities claim that optimal treatment includes metabolic analysis … If outcomes are quantitatively synthesized, we will conduct a sensitivity analysis excluding studies … Comparison of four heterogeneity measures for meta-analysis. … Bias in meta-analysis detected by a simple, graphical test.

162. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
     April 01, 2022 - (meta-analysis performed if new evidence was large relative to the studies in the original meta-analysis … ); consistency in findings between the new studies and the original meta-analysis (meta-analysis performed … performed if the strength of evidence based on the original meta-analysis was low or insufficient and … Opioids for chronic low back pain management: a Bayesian network meta- analysis. … A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken). 2020 Jun 25;25:25.

163. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
     March 01, 2025 - The linear dose-response meta-analysis showed a significant association between the risk of incident … Subgroup Analysis Based on Sex and Geographic Location We found no significant linear dose-response … • Dose-response meta- analysis also showed nonsignificant associations. … Subgroup Analysis Based on Sex and Geographic Location We found similar U-shaped nonlinear dose-response … is important to acknowledge the limitations of study-level meta-regression and dose-response meta- analysis

164. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - will be considered to be high risk of bias ● If there are no major concerns about study design or analysis … considered to be at moderate risk of bias ● If there are no major concerns about study design or analysis … and control for potential confounders was conducted with propensity score analysis (or equivalent), … in the inclusion criteria will be considered to be “prioritized”, and thus will be included in SoE analysis … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

165. Disposition of Comments for Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis -- Update of a 2007 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
     March 01, 2012 - We did not use a 0.5 correction factor for the adverse events analysis. … We did not add a 0.5 correction factor for adverse events analysis. … Similar analysis should have been done for benefits, too. … " means - meta- analysis (not likely)? … The cited article contained no such analysis, and reported no such conclusion.

166. Disposition of Comments for CER 168 Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
     January 15, 2016 - of the actual model used in the analysis, and avoid misunderstanding. … We reported the analysis using all studies in the review. … Peer reviewer #4 Methods For the Bayesian analysis, diagnostic of convergence? … Multi-intervention meta-analysis is a synonymous term for network MA. … We ran the analysis without poor quality studies.

167. Effect-Dietary-Digestible-Appendix-A (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-appendix-a.pdf
     August 31, 2023 - " or placebo* or nocebo* or random* or "prospective study" or "prospective survey" or "prospective analysis … " or prospectiv* or "quasi experimental study" or "quasi experimental analysis" or "quasiexperimental … study" or "quasiexperimental analysis" or "case control study" or "case base study" or "case referrent

168. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - Chapter 8: meta-analysis of test performance when there is a “gold standard”. … The binomial distribution of meta-analysis was preferred to model within-study variability. … A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations. … Advanced methods in meta-analysis: multivariate approach and meta-regression. … An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy.

169. Healthcare Industry Waste and Lifecycle Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-protocol.pdf
     August 23, 2023 - Life cycle analysis (LCA) provides a pathway to evaluate products, processes, and procedures within … A limitation in the analysis may be unknown associated impacts at various points from cradle to grave … What data sources, measures/indicators, and methods were used in the analysis? iii. … The technical brief will provide a trend analysis showing the interest in LCAs over time. … LCA data quality: sensitivity and uncertainty analysis.

170. Disposition of Comments: Comparative Effectiveness Review No. 239: Acute Treatments for Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
     December 29, 2020 - A meta-analysis that included 6 trials revealed that IN lidocaine reduced pain intensity at 5 minutes … “Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials.” … A relevant meta-analysis found that IV Mg reduces acute migraine attacks within 15 - 45 minutes, 120 … Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled

171. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - Matched Analysis Presentation of Results ............................................................ … Study design options include restriction and matching, while analysis options include stratification … Figure 5 is a presentation of the results of matched analysis. … This type of study poses several challenges for statistical analysis. … Otherwise, it is used in the regression analysis.

172. Osteoporosis-Bone-Fracture Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
     March 01, 2012 - Studies that reported fracture only as an adverse event were excluded from effectiveness analysis; … , and overall fracture risk in another pooled analysis … High Our pooled analysis of eight trials found an increased risk with raloxifene of hot flashes. … Moderate A pooled analysis of three trials of teriparatide found an increased risk of headaches. … High A pooled analysis of four trials of denosumab found an increased risk for infection.

173. Disposition of Comments - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2025-update-disposition-comments.pdf
     January 01, 2025 - comparators and also needs to consider several other aspects such as timepoints of assessment, analysis … to the repository 3) continues to acknowledge shortcomings of prior research through risk of bias analysis … Those not familiar with bias analysis may be confused by how high risk is the result of low and a few … Contemporary treatment of anxiety in primary care: a systematic review and meta-analysis of outcomes … A meta-analysis of brief tobacco interventions for use in integrated primary care.

174. Making Healthcare Safer IV: Interventions to Prevent Nonventilator Hospital-acquired Pneumonia (NV-HAP) for Inpatients (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
     August 05, 2024 - are at risk for NV-HAP.7 An analysis of over six million hospitalizations in the U.S. … We will not conduct a meta-analysis. … Analysis of Subgroups or Subsets We will report if the effectiveness of the PSP differs across patient … care and postoperative pneumonia in non- cardiac surgical patients: A systematic review and meta-analysis … Effect of Dysphagia Screening on Pneumonia in Acute Stroke Patients: A Systematic Review and Meta-Analysis

175. Surveillance Report: CER 30: Comparative Effectiveness of Pain Management for Hip Fracture (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
     July 08, 2015 - Local anesthetic systemic toxicity after combined psoas compartment-sciatic nerve block: analysis of … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: ! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •!

176. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
     December 11, 2015 - We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Using qualitative comparative analysis to study causal complexity. … In addition to the planned analysis, we will use quantitative comparative analysis (QCA) using the … Identify cases for use in analysis. … A study with three arms provides 2 cases for analysis. 3.

177. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
     July 06, 2015 - A. and Renin Angiotension System Modulator Meta-Analysis, I. (2012). … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •!

178. Technical Brief Disposition of Comments Report for Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
     December 14, 2012 - The flow, key questions, review of the literature and analysis are well structured and thoughtfully … The pooled analysis was presented by Dr. … (Supportive Literature: Salazar, Pooled Analysis, ASCO 2012 Tabernero, Pooled Analysis, ASCO GI 2012 … (Supportive Literature: Tabernero, Pooled Analysis, ASCO GI 2012; Salazar, Pooled Analysis, ASCO 2012 … (Supportive Literature: Tabernero, Pooled Analysis, ASCOGI 2012).

179. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
     July 01, 2012 - In my opinion, this is not a valid analysis. … The statistical methods are appropriate for this analysis. Thank you. … I would report the clinical populations separately in the primary analysis. … This section has been revised to reflect that change in analysis approach. … Important analysis regarding the benefits in ACPE are offered. Thank you.

180. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - The determination on the appropriateness of meta-analysis will be made before any data analysis; we … will not base the decision to perform meta-analysis on statistical criteria for heterogeneity. … A systematic review and meta-analysis. … Network meta-analysis for indirect treatment comparisons. … Meta-analysis in clinical trials. Controlled clinical trials. 1986 Sep;7(3):177-88.