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161. Osteoporosis-Bone-Fracture Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
     March 01, 2012 - Studies that reported fracture only as an adverse event were excluded from effectiveness analysis; … , and overall fracture risk in another pooled analysis … High Our pooled analysis of eight trials found an increased risk with raloxifene of hot flashes. … Moderate A pooled analysis of three trials of teriparatide found an increased risk of headaches. … High A pooled analysis of four trials of denosumab found an increased risk for infection.

162. DEcIDE 33: Summary Variables in Observational Resesarch: Propensity Scores and Disease Risk Scores (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
     May 01, 2012 - Matched Analysis Presentation of Results ............................................................ … Study design options include restriction and matching, while analysis options include stratification … Figure 5 is a presentation of the results of matched analysis. … This type of study poses several challenges for statistical analysis. … Otherwise, it is used in the regression analysis.

163. Disposition of Comments: Comparative Effectiveness Review No. 239: Acute Treatments for Episodic Migraine (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
     December 29, 2020 - A meta-analysis that included 6 trials revealed that IN lidocaine reduced pain intensity at 5 minutes … “Intranasal lidocaine for acute migraine: A meta-analysis of randomized controlled trials.” … A relevant meta-analysis found that IV Mg reduces acute migraine attacks within 15 - 45 minutes, 120 … Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled

164. Making Healthcare Safer IV Rapid Review: Prevention in Adults of Infection With Transmission of Multidrug-Resistant Organisms (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
     April 01, 2024 - We did not conduct a meta-analysis. … reduction in HAI incidence, but this benefit was not seen when the analysis was restricted to only … • A meta-analysis found more anxiety and depression in patients who were in infectious isolation … : A systematic review and meta- analysis. … Making health care safer: a critical analysis of patient safety practices.

165. Technical Brief Disposition of Comments Report for Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
     December 14, 2012 - The flow, key questions, review of the literature and analysis are well structured and thoughtfully … The pooled analysis was presented by Dr. … (Supportive Literature: Salazar, Pooled Analysis, ASCO 2012 Tabernero, Pooled Analysis, ASCO GI 2012 … (Supportive Literature: Tabernero, Pooled Analysis, ASCO GI 2012; Salazar, Pooled Analysis, ASCO 2012 … (Supportive Literature: Tabernero, Pooled Analysis, ASCOGI 2012).

166. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
     December 11, 2015 - We will also examine potential sources of heterogeneity using sensitivity analysis or analysis of subgroups … Using qualitative comparative analysis to study causal complexity. … In addition to the planned analysis, we will use quantitative comparative analysis (QCA) using the … Identify cases for use in analysis. … A study with three arms provides 2 cases for analysis. 3.

167. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
     July 01, 2012 - In my opinion, this is not a valid analysis. … The statistical methods are appropriate for this analysis. Thank you. … I would report the clinical populations separately in the primary analysis. … This section has been revised to reflect that change in analysis approach. … Important analysis regarding the benefits in ACPE are offered. Thank you.

168. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
     July 06, 2015 - A. and Renin Angiotension System Modulator Meta-Analysis, I. (2012). … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •!

169. Surveillance Report: CER 30: Comparative Effectiveness of Pain Management for Hip Fracture (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
     July 08, 2015 - Local anesthetic systemic toxicity after combined psoas compartment-sciatic nerve block: analysis of … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: ! … All conclusions were up to date SRC Literature Analysis: •! … All conclusions were up to date SRC Literature Analysis: •!

170. DST_Draft_Protocol_Nov_4_2013_clean (2) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
     November 12, 2013 - The determination on the appropriateness of meta-analysis will be made before any data analysis; we … will not base the decision to perform meta-analysis on statistical criteria for heterogeneity. … A systematic review and meta-analysis. … Network meta-analysis for indirect treatment comparisons. … Meta-analysis in clinical trials. Controlled clinical trials. 1986 Sep;7(3):177-88.

171. Appendix A - The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease-appendix-a.pdf
     August 31, 2023 - " or placebo* or nocebo* or random* or "prospective study" or "prospective survey" or "prospective analysis … " or prospectiv* or "quasi experimental study" or "quasi experimental analysis" or "quasiexperimental … study" or "quasiexperimental analysis" or "case control study" or "case base study" or "case referrent

172. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Long-term clinical outcomes SRC Literature Analysis: •! … Short-term mortality SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •! … Other SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •!

173. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - Long-term clinical outcomes SRC Literature Analysis: •! … Short-term mortality SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •! … Other SRC Literature Analysis: •! … Short-term quality of life SRC Literature Analysis: •!

174. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - In January 2022, we published an evolving rapid review,1 meta-analysis, and data visualization that … Data Synthesis and Analysis In previous update, we conducted a meta-analysis of controlled studies of … Was appropriate statistical analysis used? 17 Table B-3. … Up to 13 months Delta Delta analysis: 325,157 Long-term effectiveness analysis: 152,656 … Best evidence synthesis: an intelligent alternative to meta-analysis.

175. Disposition of Comments_Systematic Review: The Relationship of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-disposition-comments_0.pdf
     March 03, 2025 - and Affiliation Section Comment Response Public Reviewer #1 Methods Not convinced that the meta-analysis … The appropriateness of meta- analysis was evaluated by the similarity of the included studies. … We determined meta-analysis is warranted in this case. Public Reviewer #1 Results None. … The draft report mentions that low- carbohydrate dietary patterns were excluded from this analysis, … Popularity of commercial and non-commercial diets from 20102020: a Google trends analysis.

176. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
     April 01, 2022 - (meta-analysis performed if new evidence was large relative to the studies in the original meta-analysis … ); consistency in findings between the new studies and the original meta-analysis (meta-analysis performed … performed if the strength of evidence based on the original meta-analysis was low or insufficient and … Opioids for chronic low back pain management: a Bayesian network meta- analysis. … A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken). 2020 Jun 25;25:25.

177. Traumatic Brain Injury and Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
     January 30, 2014 - Factor"analysis"of"persistent" postconcussive"symptoms"within"a"military"sample"with"blast"exposure. … DK2" " $ Current$Literature$Analysis:$ •" No"studies"were"identified. … " $ Current$Literature$Analysis:$ •" No"studies"were"identified. … " " " " " " " DK5" " Original(Systematic(Review(Conclusions(and(Literature(Analysis( … $DESIGN:$Secondary$data$ analysis.$SETTING:$Acute$inpatient$rehabilitation$facilities.

178. Management of Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_policymaker.pdf
     June 01, 2016 - N Finding SOE BETA-BLOCKERS Propranolol vs. observation or placebo Improvement in IH Network meta-analysis … propranolol arm (fewer than 15% of children) ��� Propranolol vs. steroids Improvement in IH Network meta-analysis … Equivalent response ��� Topical timolol vs. placebo or observation Improvement in IH Network meta-analysis … more effective ��� STEROIDS Oral steroids vs. observation or placebo Improvement in IH Network meta-analysis … observation or placebo Improvement in IH Network meta-analysis N/A Intralesional steroids more effective

179. Medical Therapies for Locally Advanced Gastric Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
     January 01, 2024 - Data Synthesis: We will summarize the evidence qualitatively and quantitatively (e.g., meta- analysis … , network meta-analysis) when possible. … To assess whether pairwise meta-analysis will be appropriate, we will consider population factors such … In considering network meta-analysis, we will evaluate how these factors are distributed across direct … Estimating interactions and subgroup‐ specific treatment effects in meta‐analysis without aggregation

180. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - will be considered to be high risk of bias ● If there are no major concerns about study design or analysis … considered to be at moderate risk of bias ● If there are no major concerns about study design or analysis … and control for potential confounders was conducted with propensity score analysis (or equivalent), … in the inclusion criteria will be considered to be “prioritized”, and thus will be included in SoE analysis … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report