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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
    November 01, 2013 - During results analysis, bias occurs if investigators decide to change their analysis (e.g., change … the reported analysis was planned or post hoc. … Note: ARB=analysis reporting bias, ORB=outcome reporting bias. … Quinine for nocturnal leg cramps: a meta-analysis including unpublished data. … A sensitivity analysis for publication bias in systematic reviews.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
    May 01, 2022 - (meta-analysis performed if new evidence was large relative to the studies in the original meta-analysis … ); consistency in findings between the new studies and the original meta-analysis (meta-analysis performed … and a trial sequential analysis. … Effect of preemptive acetaminophen on opioid consumption: a meta-analysis. … Meta-Analysis Results Figure G-1.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
    January 01, 2016 - Results The literature search revealed 29 RCTs for summary and analysis and 10 observational studies … When the analysis was stratified by route of administration, the pooled risk ratio was 0.80 (95% CI … However, a recent meta-analysis of RCTs comparing IOCM and LOCM that included such studies found no … As mentioned above, one study was a network meta- analysis that pooled all outcomes without focusing … Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177-88. PMID: 3802833. 9.
  4. effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
    December 01, 2009 - Analysis Baseline treatment regimens were used to define comparison groups. … Time-Varying Exposure There were 7,840 patients included in the time-varying exposure analysis. … By not using an inception cohort we may introduce survivorship bias into the analysis. … We relied solely on VA data to conduct this analysis. … Modeling and variable selection in epidemiologic analysis.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
    December 01, 2009 - Analysis Baseline treatment regimens were used to define comparison groups. … Time-Varying Exposure There were 7,840 patients included in the time-varying exposure analysis. … By not using an inception cohort we may introduce survivorship bias into the analysis. … We relied solely on VA data to conduct this analysis. … Modeling and variable selection in epidemiologic analysis.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
    January 01, 2023 - Purpose of the Review This systematic review and meta-analysis will evaluate the Key Question (KQ) listed … We will use relevant systematic reviews and meta-analysis to identify additional existing and new literature … We will determine whether a meta-analysis is appropriate (i.e., more than 2 studies address the same … If meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates from … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
    January 01, 2023 - Subgroup analysis reported indicator 9. … Analysis Type 3. Method for Handling Missing Data 4. Statistical Analysis Method 5. … Adjusted Variables in Statistical Analysis 6. Assessment timepoint(s) 7. … Analysis Type 5. Statistical Analysis Method 6. Adjusted Variables in Statistical Analysis 7. … that was finalized before unblinded outcome data were available for analysis?
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
    March 10, 2010 - Our sensitivity analysis included long-term studies (> 6 months). … Is it that two arms would be included in each analysis? … s last observed value will be used in the primary analysis." … "For the endpoint analysis, any dropout before Week 12 would be included in the analysis as long as … analysis."
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
    January 01, 2024 - will be considered to be high risk of bias ● If there are no major concerns about study design or analysis … and control for potential confounders was conducted with propensity score analysis (or equivalent), … in the inclusion criteria will be considered to be “prioritized”, and thus will be included in SoE analysis … Dietary fats and mortality among patients with type 2 diabetes: analysis in two population based cohort … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
    March 01, 2012 - Meta-analysis or individual patient data analysis across RCTs? … Meta-analysis or individual patient data analysis across RCTs? … Meta-analysis or individual patient data analysis across RCTs? … A meta-analysis. … Meta-Analysis of RCTs If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
    April 18, 2013 - and indirect adjusted frequestist analysis needed? … What is the justification to use one in one analysis and use another in a different analysis? … We provide 2 forest plots reporting the results from network Bayesian meta-analysis. … Bayesian net work meta-analysis if being used by the FDA for policy decisions. … Our goal was a comprehensive analysis of evidence.
  12. effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
    September 21, 2012 - software packages and online tools exist for performing these calculations, such as Stata and Power Analysis … Potential reductions in the number of recruited patients available for analysis (e.g., due to loss … less overlap in propensity score distributions across cohorts), many patients will drop out of the analysis … Investigators who undertake a completed-cases analysis, which excludes patients with any missing data … - Examples include Stata, Confidence Interval Analysis, Power Analysis and Sample Size (
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
    February 05, 2025 - A recent meta- analysis of 30 randomized controlled trials of psychosocial interventions compared with … We will determine whether meta-analysis is appropriate (i.e., more than two studies address the same … If a meta-analysis is deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few … Technical Experts do not do analysis of any kind; neither do they contribute to the writing of the report
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
    January 31, 2023 - • Reviewers requested the addition of text that describes the direction of meta-analysis estimates … of KQ1 be used in the analysis of KQ2 if the key questions are combined? … Risk/benefit terminology may imply that we did some sort of risk benefit analysis. … The results and discussion sections describe findings of the analysis of tumor size. … Data are insufficient for a network meta- analysis and indirect comparisons.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
    January 01, 2012 - decision analysis approach. … Benefit-Less-Risk Analysis Benefit-less-risk analysis (BLRA) combines benefit and harm into a single … Multicriteria Decision Analysis Multicriteria decision analysis allows for systematic decisionmaking … Probabilistic analysis and sensitivity analysis are two examples of quantitative approaches that reviewers … Studies included in a network meta-analysis should be, as in any conventional meta-analysis, comparable
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - Study and Independent Patient Level Meta-Analysis Selection: Results from study- and patient-level meta-analysis … Did the analysis include an intention-to-treat analysis? … The hazards of scoring the quality of clinical trials for meta-analysis. … meta: Meta-Analysis, R package version 1.5-0. 55. R Development Core Team. 2010. … metafor: Meta-Analysis Package for R. R package version 1.1-0.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
    June 07, 2013 - It may be of interest to include analysis comparing those who are nullipara to those who have been … Narod study-- included in the table but excluded from meta analysis?) … This seems like a reasonable exploratory analysis potentially? … Our systematic review incorporates a meta-analysis of published data rather than a pooled analysis or … individual patient-level meta-analysis.
  18. effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
    January 01, 2009 - Meta-analysis: combining the results of independent experiments. … Berlin J, for the University of Pennsylvania Meta-analysis Blinding Study Group. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Meta-analysis: combining the results of independent experiments.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
    November 29, 2023 - .36 When meta-analysis is not possible, we will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a narrative Summary of Findings table. … Protein Intake and Sarcopenia in Older Adults: A Systematic Review and Meta-Analysis. … Meta-Analysis with R. 2015. 39. Higgins JP, Thompson SG, Deeks JJ, Altman DG.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
    January 01, 2014 - However, use of the gold standard synovial fluid analysis for diagnosis of gout is difficult and seldom … In fact, evidence from a 2011 survey of rheumatologists suggests that SF analysis is underused in the … Studies will also be included if they compare the accuracy of synovial fluid aspiration and analysis … Comparators will be microscopic synovial fluid analysis. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.

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