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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
November 01, 2013 - During results analysis, bias occurs if
investigators decide to change their analysis (e.g., change … the reported analysis
was planned or post hoc. … Note: ARB=analysis reporting bias, ORB=outcome reporting bias. … Quinine for
nocturnal leg cramps: a meta-analysis including
unpublished data. … A sensitivity analysis for
publication bias in systematic reviews.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
May 01, 2022 - (meta-analysis performed if new evidence
was large relative to the studies in the original meta-analysis … ); consistency in findings between
the new studies and the original meta-analysis (meta-analysis performed … and a trial sequential analysis. … Effect of
preemptive acetaminophen on opioid
consumption: a meta-analysis. … Meta-Analysis Results
Figure G-1.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - Results
The literature search revealed 29 RCTs for summary
and analysis and 10 observational studies … When the analysis was
stratified by route of administration, the pooled risk ratio
was 0.80 (95% CI … However, a recent
meta-analysis of RCTs comparing IOCM and LOCM that
included such studies found no … As mentioned above, one study was a network meta-
analysis that pooled all outcomes without focusing … Meta-analysis in clinical trials. Control
Clin Trials. 1986 Sep;7(3):177-88. PMID: 3802833.
9.
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effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - Analysis
Baseline treatment regimens were used to define comparison groups. … Time-Varying Exposure
There were 7,840 patients included in the time-varying exposure analysis. … By not using an inception cohort we may introduce survivorship bias into the
analysis. … We relied solely on VA data to conduct this analysis. … Modeling and variable
selection in epidemiologic analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - Analysis
Baseline treatment regimens were used to define comparison groups. … Time-Varying Exposure
There were 7,840 patients included in the time-varying exposure analysis. … By not using an inception cohort we may introduce survivorship bias into the
analysis. … We relied solely on VA data to conduct this analysis. … Modeling and variable
selection in epidemiologic analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - Purpose of the Review
This systematic review and meta-analysis will evaluate the Key Question (KQ) listed … We will use relevant systematic reviews and meta-analysis to identify
additional existing and new literature … We will determine whether a meta-analysis is appropriate (i.e., more than 2 studies address
the same … If
meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates
from … Technical Experts do not do analysis of any kind;
neither do they contribute to the writing of the report
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - Subgroup analysis reported indicator
9. … Analysis Type
3. Method for Handling Missing Data
4. Statistical Analysis Method
5. … Adjusted Variables in Statistical Analysis
6. Assessment timepoint(s)
7. … Analysis Type
5. Statistical Analysis Method
6. Adjusted Variables in Statistical Analysis
7. … that
was finalized before unblinded outcome data were available for analysis?
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - Our
sensitivity analysis included long-term studies (> 6 months). … Is it that two arms
would be included in each analysis? … s last observed value will be used in
the primary analysis." … "For the endpoint analysis, any dropout before Week 12 would be
included in the analysis as long as … analysis."
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - will be considered to be
high risk of bias
● If there are no major concerns about study design or analysis … and control for potential
confounders was conducted with propensity score analysis (or equivalent), … in the inclusion
criteria will be considered to be “prioritized”, and thus will be included in SoE analysis … Dietary fats and mortality among patients with type 2 diabetes:
analysis in two population based cohort … Technical Experts do not do
analysis of any kind nor do they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
March 01, 2012 - Meta-analysis or
individual patient
data analysis across
RCTs? … Meta-analysis or
individual patient
data analysis across
RCTs? … Meta-analysis or
individual patient
data analysis across
RCTs? … A meta-analysis. … Meta-Analysis of RCTs
If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - and indirect adjusted frequestist
analysis needed? … What is the justification to use one in
one analysis and use another in a different analysis? … We provide 2 forest plots reporting the results
from network Bayesian meta-analysis. … Bayesian net work meta-analysis if
being used by the FDA for policy decisions. … Our goal was a comprehensive analysis of
evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - software
packages and online tools exist for performing
these calculations, such as Stata and Power
Analysis … Potential reductions in the number of
recruited patients available for analysis (e.g., due
to loss … less overlap in propensity score distributions
across cohorts), many patients will drop out of the
analysis … Investigators
who undertake a completed-cases analysis, which
excludes patients with any missing data … - Examples include Stata, Confidence Interval
Analysis, Power Analysis and Sample Size
(
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - A recent meta-
analysis of 30 randomized controlled trials of psychosocial interventions compared with … We will determine whether meta-analysis is appropriate (i.e., more than two studies address the
same … If a meta-analysis is
deemed appropriate, we plan to use the DerSimonian and Laird random-effects method … Hartung-Knapp-Sidik-Jonkman approach and its modification
for random-effects meta-analysis with few … Technical Experts do not do
analysis of any kind; neither do they contribute to the writing of the report
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
January 31, 2023 - • Reviewers requested the addition of text that describes the direction of meta-analysis
estimates … of KQ1 be used in the analysis of KQ2 if the key
questions are combined? … Risk/benefit
terminology may
imply that we did
some sort of risk
benefit analysis. … The results
and discussion
sections describe
findings of the
analysis of
tumor size. … Data are
insufficient for a
network meta-
analysis and
indirect
comparisons.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - decision analysis
approach. … Benefit-Less-Risk Analysis
Benefit-less-risk analysis (BLRA) combines benefit and harm into a single … Multicriteria Decision Analysis
Multicriteria decision analysis allows for systematic decisionmaking … Probabilistic analysis and sensitivity
analysis are two examples of quantitative approaches that reviewers … Studies included in
a network meta-analysis should be, as in any conventional meta-analysis, comparable
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
June 16, 2010 - Study and Independent Patient Level Meta-Analysis Selection:
Results from study- and patient-level meta-analysis … Did the analysis include an intention-to-treat analysis? … The hazards of scoring the quality of clinical
trials for meta-analysis. … meta: Meta-Analysis, R package version 1.5-0.
55. R Development Core Team. 2010. … metafor: Meta-Analysis Package for R. R package version
1.1-0.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - It may be of
interest to include analysis comparing those who are
nullipara to those who have been … Narod study--
included in the table but excluded from meta analysis?) … This seems like a
reasonable exploratory analysis potentially? … Our systematic review incorporates a meta-analysis
of published data rather than a pooled analysis or … individual patient-level meta-analysis.
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effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
January 01, 2009 - Meta-analysis: combining the results of independent experiments. … Berlin J, for the University of Pennsylvania Meta-analysis Blinding Study Group. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Does blinding of readers affect the results of meta-analysis? Lancet 1997;350:185-6. … Meta-analysis: combining the results of independent experiments.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - .36 When meta-analysis is not possible, we
will provide a qualitative synthesis. … When meta-analysis is possible, we will synthesize
data using a Hartung, Knapp, Sidik, and Jonkman … If meta-analysis is not possible, we will present results in a
narrative Summary of Findings table. … Protein Intake and Sarcopenia in
Older Adults: A Systematic Review and Meta-Analysis. … Meta-Analysis with R. 2015.
39. Higgins JP, Thompson SG, Deeks JJ, Altman DG.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
January 01, 2014 - However, use of the gold standard synovial fluid
analysis for diagnosis of gout is difficult and seldom … In fact,
evidence from a 2011 survey of rheumatologists suggests that SF analysis is underused in
the … Studies will also be included if
they compare the accuracy of synovial fluid aspiration and analysis … Comparators will be
microscopic synovial fluid analysis. … Bias in meta-analysis detected by a
simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.