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1. Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/methods-binary-outcomes-evaluation/research
   March 20, 2013 - Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes … We aimed to compare separate (univariate) with joint (multivariate) meta-analysis in real examples and … We analyzed these data with univariate and multivariate meta-analysis. … In principle, multivariate meta-analysis utilizes more information through the correlations; therefore … Multivariate meta-analysis should be preferred over univariate meta-analysis for estimating differences

2. Multi-Criteria Decision Analysis Techniques to Integrate Stakeholder Preferences in Comparative Effectiveness Research (Audio Presentation) | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/stakeholders-engagement-others/slides-2012
   August 27, 2012 - Multi-Criteria Decision Analysis Techniques to Integrate Stakeholder Preferences in Comparative Effectiveness … This webinar from August 27, 2012 introduces the conceptual basis for multi-criteria decision analysis … describes how two preference elicitation techniques, Analytic Hierarchy Process (AHP) and Conjoint Analysis … These techniques are now widely used for cost-benefit analysis in health and environmental economics. … He chairs the ISPOR Conjoint Analysis Experimental Design Task Force.

3. Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/metanalysis-proportion-rate-comparison/research
   November 04, 2013 - Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates Research Report November … systematic reviews it is appropriate to summarize proportions and rates (e.g., incidence rates) using meta-analysis … Many statistical methods can be used for meta-analysis of rates and proportions. … an extensive simulation study to assess the statistical properties of alternative approaches to meta-analysis … summary proportion or rate and its defining parameters (mean, variance), the number of studies per meta-analysis

4. mmeta: Exact Bayesian Inference for Multivariate Meta-analysis of Binary Outcomes | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/mmeta/abstract
   February 11, 2014 - mmeta: Exact Bayesian Inference for Multivariate Meta-analysis of Binary Outcomes Abstract February … 11, 2014 Topic Abstract Multivariate meta-analysis is useful in combining evidence from … We proposed a novel model for multivariate meta-analysis of binary outcomes where the risks are modeled … empirical Bayes method for evaluating overall and study-specific treatment effects in multivariate meta-analysis … Approach mmeta is a free, cross-platform, open-source program for performing meta-analysis for combining

5. Quantitative Synthesis: Chapter 5. Network Meta-Analysis (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
   February 01, 2018 - Network Meta-Analysis Quantitative Synthesis Chapter 5. … Network meta-analysis schematic • Network meta-analysis can be explained thus: ► If we know that intervention … A Bayesian network meta-analysis for binary outcome: how to do it. … Checking consistency in mixed treatment comparison meta-analysis. … Network Meta-Analysis Learning objective Network meta-analysis Network meta-analysis schematic Assumptions

6. Amyloidosis | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/amyloidosis
   May 02, 2011 - Serum-Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias … Research Protocol Archived May 2, 2011 Serum Free Light Chain Analysis for the … Research Needs Systematic Review Archived September 19, 2012 Serum Free Light Chain Analysis

7. Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
   January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis … research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Maarten J. … and Conjoint Analysis  Multi-criteria Decision analysis (MCDA) is a subdiscipline of operations research … Slide 7 Conjoint analysis  Each participant receives N choice sets. … Conjoint analysis methods MCDA (e.g.

8. Serum free light chain analysis for the diagnosis | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/get-involved/nominated-topics/serum-free-light-chain-analysis-for-the-diagnosis
   June 17, 2009 - Serum free light chain analysis for the diagnosis Serum Free Light Chain Analysis for the Diagnosis

9. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
   June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard Meta-analysis … Multivariate meta-analysis of sensitivity and specificity (i.e., joint analysis of both) should be performed … Ideally, the analysis of both quantities should be performed jointly using multivariate meta-analysis … An independent meta-analysis of sensitivity and specificity can be done, or a joint meta-analysis of … Qualitative analysis with graphs and quantitative analysis with proper methods are encouraged.

10. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard Meta-analysis … Multivariate meta-analysis of sensitivity and specificity (i.e., joint analysis of both) should be performed … Ideally, the analysis of both quantities should be performed jointly using multivariate meta-analysis … An independent meta-analysis of sensitivity and specificity can be done, or a joint meta-analysis of … Qualitative analysis with graphs and quantitative analysis with proper methods are encouraged.

11. Obesity in Children | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/obesity-children
    February 09, 2017 - June 10, 2013 Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis … 10, 2013 Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis

12. Patient Safety | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/patient-safety
    October 19, 2016 - Pilot Study using Medicare Part B Drug Data Abstract January 1, 2005 Critical Analysis … Practices in Nursing Home Settings Research Protocol Archived July 30, 2015 Critical Analysis

13. Child Care | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/child-care
    January 24, 2012 - June 10, 2013 Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis … 10, 2013 Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis

14. An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/bivariate-methods-utility_research.pdf
    November 01, 2012 - Worked Meta-Analysis Example viii An Empirical Assessment of Bivariate Methods for Meta-Analysis … Bivariate Meta-Analysis Methods We fit bivariate random effects meta-analysis models that allow for … Variability Meta-Analysis Method Univariate Meta-Analysis (Estimation of Heterogeneity) Bivariate … of a full Bayesian analysis. … Worked Meta-Analysis Example Here we present a worked meta-analysis example using several of the

15. Safety | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/safety
    August 05, 2010 - Pilot Study using Medicare Part B Drug Data Abstract January 1, 2005 Critical Analysis … Practices in Nursing Home Settings Research Protocol Archived July 30, 2015 Critical Analysis

16. Critical Analysis of the Evidence for Patient Safety Practices | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/patient-safety-practices/research-protocol
    December 06, 2011 - Current Page Topic Timeline Nov. 8, 2011 Topic Initiated Dec. 6, 2011 Research Protocol Critical Analysis … Background and Objectives for the Systematic Review The critical systematic review and analysis of … The analysis will assess the evidence of the effectiveness of new safe practices and the adoption of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have

17. Comparative Effectiveness of Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis of Individual Patient Data from Ten Randomized Trials (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
    February 01, 2010 - Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis … Statistical Analysis All analyses followed the intention-to-treat principle. … Analysis of BARI-like patients in Northern New England. … Can meta- analysis help target interventions at individuals most likely to benefit? … A hierarchical Bayesian meta-analysis. Ann Intern Med 2003;138:777-786. 32.

18. Meta-Analysis of Test Performance When There Is a "Gold Standard" | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis
    June 01, 2012 - Meta-Analysis of Test Performance When There Is a "Gold Standard" Timeline November … Initiated June 01, 2012 Methods Guide – Chapter Chapter 8: Meta-Analysis … There Is a “Gold Standard” September 01, 2013 Presentation Meta-analysis

19. Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/cognitive-measures-harmonization/research
    March 21, 2013 - Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis … harmonization which could be used in the context of summary data and/or individual participant data meta-analysis … The latent variable analysis underscored the difficulty harmonizing these cognition data. … methods of combining complex constructs using aggregate data (AD) or individual participant data meta-analysis … data which are required to assess the potential for bias in combining complex outcomes using AD meta-analysis

20. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay
    May 02, 2011 - Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias … May 02, 2011 Research Protocol Archived Serum-Free Light Chain Analysis … August 23, 2012 Systematic Review Archived Serum Free Light Chain Analysis