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effectivehealthcare.ahrq.gov/products/methods-binary-outcomes-evaluation/research
March 20, 2013 - Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes … We aimed to compare separate (univariate) with joint (multivariate) meta-analysis in real examples and … We analyzed these data with univariate and multivariate meta-analysis. … In principle, multivariate meta-analysis utilizes more information through the correlations; therefore … Multivariate meta-analysis should be preferred over univariate meta-analysis for estimating differences
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effectivehealthcare.ahrq.gov/products/stakeholders-engagement-others/slides-2012
August 27, 2012 - Multi-Criteria Decision Analysis Techniques to Integrate Stakeholder Preferences in Comparative Effectiveness … This webinar from August 27, 2012 introduces the conceptual basis for multi-criteria decision analysis … describes how two preference elicitation techniques, Analytic Hierarchy Process (AHP) and Conjoint Analysis … These techniques are now widely used for cost-benefit analysis in health and environmental economics. … He chairs the ISPOR Conjoint Analysis Experimental Design Task Force.
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effectivehealthcare.ahrq.gov/products/metanalysis-proportion-rate-comparison/research
November 04, 2013 - Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates
Research Report November … systematic reviews it is appropriate to summarize proportions and rates (e.g., incidence rates) using meta-analysis … Many statistical methods can be used for meta-analysis of rates and proportions. … an extensive simulation study to assess the statistical properties of alternative approaches to meta-analysis … summary proportion or rate and its defining parameters (mean, variance), the number of studies per meta-analysis
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effectivehealthcare.ahrq.gov/products/mmeta/abstract
February 11, 2014 - mmeta: Exact Bayesian Inference for Multivariate Meta-analysis of Binary Outcomes
Abstract February … 11, 2014
Topic Abstract
Multivariate meta-analysis is useful in combining evidence from … We proposed a novel model for multivariate meta-analysis of binary outcomes where the risks are modeled … empirical Bayes method for evaluating overall and study-specific treatment effects in multivariate meta-analysis … Approach
mmeta is a free, cross-platform, open-source program for performing meta-analysis for combining
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - Network Meta-Analysis
Quantitative Synthesis
Chapter 5. … Network meta-analysis schematic
• Network meta-analysis can be explained thus:
► If we know that intervention … A Bayesian network meta-analysis for binary outcome: how to do it. … Checking consistency in mixed treatment comparison meta-analysis. … Network Meta-Analysis
Learning objective
Network meta-analysis
Network meta-analysis schematic
Assumptions
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effectivehealthcare.ahrq.gov/health-topics/amyloidosis
May 02, 2011 - Serum-Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias … Research Protocol
Archived
May 2, 2011
Serum Free Light Chain Analysis for the … Research Needs
Systematic Review
Archived
September 19, 2012
Serum Free Light Chain Analysis
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effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis … research using
multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA)
Maarten J. … and Conjoint Analysis
Multi-criteria Decision analysis (MCDA) is a subdiscipline of operations research … Slide 7
Conjoint analysis
Each participant receives N choice sets. … Conjoint analysis methods
MCDA (e.g.
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/serum-free-light-chain-analysis-for-the-diagnosis
June 17, 2009 - Serum free light chain analysis for the diagnosis
Serum Free Light Chain Analysis for the Diagnosis
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard
Meta-analysis … Multivariate meta-analysis of sensitivity and specificity (i.e., joint analysis of both) should be performed … Ideally, the analysis of both quantities should be performed jointly using multivariate meta-analysis … An independent meta-analysis of sensitivity and specificity can be done, or a joint meta-analysis of … Qualitative analysis with graphs and quantitative analysis with proper methods are encouraged.
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard
Meta-analysis … Multivariate meta-analysis of sensitivity and specificity (i.e., joint analysis of both) should be performed … Ideally, the analysis of both quantities should be performed jointly using multivariate meta-analysis … An independent meta-analysis of sensitivity and specificity can be done, or a joint meta-analysis of … Qualitative analysis with graphs and quantitative analysis with proper methods are encouraged.
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effectivehealthcare.ahrq.gov/health-topics/obesity-children
February 09, 2017 - June 10, 2013
Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis … 10, 2013
Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis
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effectivehealthcare.ahrq.gov/health-topics/patient-safety
October 19, 2016 - Pilot Study using Medicare Part B Drug Data
Abstract
January 1, 2005
Critical Analysis … Practices in Nursing Home Settings
Research Protocol
Archived
July 30, 2015
Critical Analysis
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effectivehealthcare.ahrq.gov/health-topics/child-care
January 24, 2012 - June 10, 2013
Childhood Obesity Prevention Programs: Comparative Effectiveness Review and Meta-Analysis … 10, 2013
Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/bivariate-methods-utility_research.pdf
November 01, 2012 - Worked Meta-Analysis Example
viii
An Empirical Assessment of Bivariate Methods for
Meta-Analysis … Bivariate Meta-Analysis Methods
We fit bivariate random effects meta-analysis models that allow for … Variability
Meta-Analysis
Method
Univariate Meta-Analysis
(Estimation of
Heterogeneity)
Bivariate … of a full
Bayesian analysis. … Worked Meta-Analysis Example
Here we present a worked meta-analysis example using several of the
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effectivehealthcare.ahrq.gov/health-topics/safety
August 05, 2010 - Pilot Study using Medicare Part B Drug Data
Abstract
January 1, 2005
Critical Analysis … Practices in Nursing Home Settings
Research Protocol
Archived
July 30, 2015
Critical Analysis
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effectivehealthcare.ahrq.gov/products/patient-safety-practices/research-protocol
December 06, 2011 - Current Page Topic Timeline Nov. 8, 2011 Topic Initiated Dec. 6, 2011 Research Protocol Critical Analysis … Background and Objectives for the Systematic Review
The critical systematic review and analysis of … The analysis will assess the evidence of the effectiveness of new safe practices and the adoption of … Technical Experts do not do analysis of any kind nor contribute to the writing of the report and have
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_addendum.pdf
February 01, 2010 - Coronary Bypass Surgery and Percutaneous Coronary Interventions for Multivessel Disease: A Pooled Analysis … Statistical Analysis
All analyses followed the intention-to-treat principle. … Analysis of BARI-like
patients in Northern New England. … Can meta-
analysis help target interventions at
individuals most likely to benefit? … A hierarchical
Bayesian meta-analysis. Ann Intern Med
2003;138:777-786.
32.
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effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis
June 01, 2012 - Meta-Analysis of Test Performance When There Is a "Gold Standard"
Timeline
November … Initiated
June 01, 2012
Methods Guide – Chapter
Chapter 8: Meta-Analysis … There Is a “Gold Standard”
September 01, 2013
Presentation
Meta-analysis
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effectivehealthcare.ahrq.gov/products/cognitive-measures-harmonization/research
March 21, 2013 - Harmonization of Cognitive Measures in Individual Participant Data and Aggregate Data Meta-Analysis … harmonization which could be used in the context of summary data and/or individual participant data meta-analysis … The latent variable analysis underscored the difficulty harmonizing these cognition data. … methods of combining complex constructs using aggregate data (AD) or individual participant data meta-analysis … data which are required to assess the potential for bias in combining complex outcomes using AD meta-analysis
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effectivehealthcare.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay
May 02, 2011 - Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias … May 02, 2011
Research Protocol
Archived
Serum-Free Light Chain Analysis … August 23, 2012
Systematic Review
Archived
Serum Free Light Chain Analysis