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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
March 01, 2013 - Thus the meta-analysis of
three “mega-trials” will be more reliable than the meta-analysis of three … • Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Bayesian methods
in meta-analysis and evidence synthesis. … Statistical power analysis for the
behavioral sciences, 2nd ed.
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effectivehealthcare-admin.ahrq.gov/products/procalcitonin/research-protocol
December 01, 2019 - Analysis: adjustment for potential confounders and intention-to-treat analysis. … Intention-to-treat analysis has been done for RCTs.
Poor. … For RCTs, intention-to-treat analysis is lacking. … analysis
↓
Single-arm study, post-hoc multivariate analysis
Less informative
Single-arm … For RCTs, intention-to-treat analysis is lacking.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
October 01, 2016 - , extreme value analysis,
dimensional analysis).166 In addition, software production techniques, such … Meta-analysis, decision analysis,
and cost-effectiveness analysis: methods for
quantitative synthesis … Sensitivity analysis in the context
of uncertainty analysis for computationally
intensive models. … Sensitivity analysis versus
uncertainty analysis: When to use what? … Bias analysis
via missing-data methods.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity
• ≥20% differential on other demographic variables Yes:
• Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group
No:
• Per-protocol analysis with ≤90% … extreme or high
• Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - example, sex) can
produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis
The complete case analysis strategy restricts the analysis to patients with … Using causal
diagrams to guide analysis in missing data
problems. … Using causal
diagrams to guide analysis in missing data
problems.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - MRI and CT performed similarly when patients
with HCC were the unit of analysis, but sensitivity was … higher for MRI than for CT when HCC lesions were the
unit of analysis (pooled difference 0.09; 95% … Surveillance
settings
Unit of analysis:
patients with
HCC
CT Sensitivity: Low
Specificity: Low … Surveillance
settings
Unit of analysis:
patients with
HCC
MRI or PET Insufficient No evidence … Nonsurveillance
settings
Unit of analysis:
HCC lesions
CT Sensitivity:
Moderate
Specificity:
-
effectivehealthcare-admin.ahrq.gov/products/stent-clopidogrel-practice/research
January 01, 2020 - Landmark Analyses Based on Clopidogrel Use
Landmark analysis is a form of survival analysis that classifies … Limitations
There are two important caveats to this analysis. … Statistical analysis: Eisenstein, Anstrom, Shaw, Tuttle. … Diagram of 6-month landmark analysis
Figure 1B. … Diagram of 12-month landmark analysis
Figure 2A.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates
The reviewers decided on the third analysis … Systematic Review Example:
Analysis Option 2 — Pooled Data Analysis
Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis
Here is an example of the analysis … Analysis options 1, 2, and 3 are recommended.
Analysis option 4 requires expert statistical help.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates
The reviewers decided on the third analysis … Systematic Review Example:
Analysis Option 2 — Pooled Data Analysis
Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis
Here is an example of the analysis … Analysis options 1, 2, and 3 are recommended.
Analysis option 4 requires expert statistical help.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s166.pdf
October 01, 2007 - meta-analysis. … Systematic Reviews
in Health Care: Meta-Analysis in Context. … Bayesian methods in meta
analysis. In: Methods for Meta-Analysis n Medical Research. … Bayesian approaches to ran-
dom-effects meta-analysis: a comparative study. … The random effects procedure
is then followed as a normal meta-analysis of 2 studies.
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effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
January 01, 2021 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … Therapeutic vaccination for chronic hepatitis B: A systematic review and meta-analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi: 10.1111
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
June 09, 2021 - TEP #6 General Cost analysis – SRS can generate huge bills.
Something to note. … analysis and
outcome in sufficient detail. … It was
clear the reason of not included meta-analysis.
Noted. … Was the analysis conducted
with incorrectly assigned trials? … Consider pooling these
analysis (but do include the separate analysis as
well)grammatical page 18
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - Rubella Immunity in Pregnant Iranian
Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic
Review and Meta-Analysis. … A Systematic Review and Meta-
Analysis. … Risk analysis : an official publication of
the Society for Risk Analysis. 2016;36(7):1297-314. doi:
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
January 24, 2022 - N1 total positive cohort included in analysis N2 total negative (control) cohort included in analysis … Delta analysis, and before August 30, 2020 for long-term effectiveness analysis Delta virus analysis … effectiveness analysis: 11,186
Delta analysis: 274,830
Long-term effectiveness analysis: 141,417 Delta … analysis: 40
Long-term effectiveness analysis: 81 Delta analysis: 50,287
Long-term effectiveness analysis … : 11,105 Delta analysis: 1,494
Long-term effectiveness analysis: 7,167 Delta analysis: 273,336
Long-term
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effectivehealthcare-admin.ahrq.gov/products/peripheral-nerve-blocks/protocol
May 01, 2024 - A sensitivity analysis will be conducted to compare the results from the full set to the results with … Transversus Abdominis Plane Block for Post Hysterectomy Pain: A Systematic Review and Meta-Analysis. … with trial sequential analysis. … and trial sequential analysis. … Technical Experts do not conduct analysis or contribute to the writing of the report.
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effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research-protocol
December 01, 2019 - Study and Independent Patient Level Meta-Analysis Selection:
Results from study- and patient-level meta-analysis … Did the analysis include an intention-to-treat analysis? … The hazards of scoring the quality of clinical trials for meta-analysis. … Schwarzer G. 2010. meta: Meta-Analysis, R package version 1.5-0.
R Development Core Team. 2010. … The TEP does not do analysis of any kind nor contribute to the writing of the report.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0320_06-17-2009.pdf
January 01, 2009 - 10
1
Results of Topic Selection Process & Next Steps
Serum free light chain assay analysis … presents a series of questions for a review on the effectiveness of serum
free light chain (FLC) assay analysis … Intervention(s): Serum FLC analysis. … Serum Free Light Chain Assay Analysis
Nomination Summary Document
http://effectivehealthcare.ahrq.gov … Is there improved diagnostic and/or therapeutic accuracy for FLC analysis in
conjunction with serum
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - We included data from pooled analysis articles in our meta-
analysis if (1) none of the individual studies … included in
the pooled analysis had already been included for meta-
analysis, (2) at least half the … under consideration in the analysis, and (3) data
in the pooled analysis were presented such that inclusion … in
the current meta-analysis was feasible. … A pooled meta-analysis of 11
studies (3 case-control, 1 pooled analysis, and 7 cohort,
of which 4
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Analysis and Interpretation
Analysis and interpretation of registry data begin
with answering a series … Analysis of registry outcomes first requires an
analysis of the completeness of data collection and
data … plan that contains sufficient detail to
explain the main focus and proposed methods of analysis … Analysis
• Accepted analytic techniques are used; these may be augmented by new or novel approaches … Analysis
• Loss to followup is characterized at key stages during the conduct of the study.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/reporting.ppt
September 01, 2009 - A systematic review and meta-analysis of randomized placebo-controlled trials. … Methods: Additional Analyses
Additional analysis, such as a subgroup analysis or a meta-regression, should … Systematic review and meta-analysis of randomised controlled trials. BMJ 2005;331:313-21. … Meta-analysis: chondroitin for osteoarthritis of the knee or hip. … A systematic review and meta-analysis of randomized placebo-controlled trials.