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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Thus the meta-analysis of three “mega-trials” will be more reliable than the meta-analysis of three … • Only widely accepted composite outcomes should be used in meta-analysis. … Distinguish between prespecified and post hoc analysis. … Bayesian methods in meta-analysis and evidence synthesis. … Statistical power analysis for the behavioral sciences, 2nd ed.
  2. effectivehealthcare-admin.ahrq.gov/products/procalcitonin/research-protocol
    December 01, 2019 - Analysis: adjustment for potential confounders and intention-to-treat analysis. … Intention-to-treat analysis has been done for RCTs. Poor. … For RCTs, intention-to-treat analysis is lacking. … analysis ↓ Single-arm study, post-hoc multivariate analysis Less informative Single-arm … For RCTs, intention-to-treat analysis is lacking.
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
    October 01, 2016 - , extreme value analysis, dimensional analysis).166 In addition, software production techniques, such … Meta-analysis, decision analysis, and cost-effectiveness analysis: methods for quantitative synthesis … Sensitivity analysis in the context of uncertainty analysis for computationally intensive models. … Sensitivity analysis versus uncertainty analysis: When to use what? … Bias analysis via missing-data methods.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharm-ptsd-update-appendix-g-1.xlsx
    November 12, 2020 - Selection Bias Domain: ITT Analysis? Performance Bias Domain: Care Providers Masked? … education, or PTSD severity • ≥20% differential on other demographic variables Yes: • Study stated ITT analysis … • >90% of randomized participants analyzed in allocated group No: • Per-protocol analysis with ≤90% … extreme or high • Measurement attrition (overall or differential) moderate paired with CA (completer analysis … Also, MI computation used group as the unit of analysis (means, across groups) rather than individuals
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - example, sex) can produce unbiased results in analysis … removed in analysis (see below sections for analytic strategies). … Complete Case Analysis The complete case analysis strategy restricts the analysis to patients with … Using causal diagrams to guide analysis in missing data problems. … Using causal diagrams to guide analysis in missing data problems.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - MRI and CT performed similarly when patients with HCC were the unit of analysis, but sensitivity was … higher for MRI than for CT when HCC lesions were the unit of analysis (pooled difference 0.09; 95% … Surveillance settings Unit of analysis: patients with HCC CT Sensitivity: Low Specificity: Low … Surveillance settings Unit of analysis: patients with HCC MRI or PET Insufficient No evidence … Nonsurveillance settings Unit of analysis: HCC lesions CT Sensitivity: Moderate Specificity:
  7. effectivehealthcare-admin.ahrq.gov/products/stent-clopidogrel-practice/research
    January 01, 2020 - Landmark Analyses Based on Clopidogrel Use Landmark analysis is a form of survival analysis that classifies … Limitations There are two important caveats to this analysis. … Statistical analysis: Eisenstein, Anstrom, Shaw, Tuttle. … Diagram of 6-month landmark analysis   Figure 1B. … Diagram of 12-month landmark analysis   Figure 2A.
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysisAnalysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.
  9. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - The systematic reviewers first attempted to use analysis option 3, then moved on to analysis option 2 … Systematic Review Example: Analysis Option 3 — Naïve Estimates The reviewers decided on the third analysis … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Dashed line = line of perfect agreement … Systematic Review Example: Analysis Option 2 — Pooled Data Analysis Here is an example of the analysisAnalysis options 1, 2, and 3 are recommended. Analysis option 4 requires expert statistical help.
  10. S166 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/s166.pdf
    October 01, 2007 - meta-analysis. … Systematic Reviews in Health Care: Meta-Analysis in Context. … Bayesian methods in meta analysis. In: Methods for Meta-Analysis n Medical Research. … Bayesian approaches to ran- dom-effects meta-analysis: a comparative study. … The random effects procedure is then followed as a normal meta-analysis of 2 studies.
  11. effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
    January 01, 2021 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … Therapeutic vaccination for chronic hepatitis B: A systematic review and meta-analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi: 10.1111
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-disposition-comments.pdf
    June 09, 2021 - TEP #6 General Cost analysis – SRS can generate huge bills. Something to note. … analysis and outcome in sufficient detail. … It was clear the reason of not included meta-analysis. Noted. … Was the analysis conducted with incorrectly assigned trials? … Consider pooling these analysis (but do include the separate analysis as well)grammatical page 18
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
    January 30, 2020 - Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. … A systematic review and meta-analysis. … : A Systematic Review and Meta-Analysis. … A Systematic Review and Meta- Analysis. … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi:
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
    January 24, 2022 - N1 total positive cohort included in analysis N2 total negative (control) cohort included in analysis … Delta analysis, and before August 30, 2020 for long-term effectiveness analysis Delta virus analysis … effectiveness analysis: 11,186 Delta analysis: 274,830 Long-term effectiveness analysis: 141,417 Delta … analysis: 40 Long-term effectiveness analysis: 81 Delta analysis: 50,287 Long-term effectiveness analysis … : 11,105 Delta analysis: 1,494 Long-term effectiveness analysis: 7,167 Delta analysis: 273,336 Long-term
  15. effectivehealthcare-admin.ahrq.gov/products/peripheral-nerve-blocks/protocol
    May 01, 2024 - A sensitivity analysis will be conducted to compare the results from the full set to the results with … Transversus Abdominis Plane Block for Post Hysterectomy Pain: A Systematic Review and Meta-Analysis. … with trial sequential analysis. … and trial sequential analysis. … Technical Experts do not conduct analysis or contribute to the writing of the report.
  16. effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research-protocol
    December 01, 2019 - Study and Independent Patient Level Meta-Analysis Selection: Results from study- and patient-level meta-analysis … Did the analysis include an intention-to-treat analysis? … The hazards of scoring the quality of clinical trials for meta-analysis. … Schwarzer G. 2010. meta: Meta-Analysis, R package version 1.5-0. R Development Core Team. 2010. … The TEP does not do analysis of any kind nor contribute to the writing of the report.
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0320_06-17-2009.pdf
    January 01, 2009 - 10 1 Results of Topic Selection Process & Next Steps  Serum free light chain assay analysis … presents a series of questions for a review on the effectiveness of serum free light chain (FLC) assay analysis … Intervention(s): Serum FLC analysis. … Serum Free Light Chain Assay Analysis Nomination Summary Document http://effectivehealthcare.ahrq.gov … Is there improved diagnostic and/or therapeutic accuracy for FLC analysis in conjunction with serum
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
    June 01, 2013 - We included data from pooled analysis articles in our meta- analysis if (1) none of the individual studies … included in the pooled analysis had already been included for meta- analysis, (2) at least half the … under consideration in the analysis, and (3) data in the pooled analysis were presented such that inclusion … in the current meta-analysis was feasible. … A pooled meta-analysis of 11 studies (3 case-control, 1 pooled analysis, and 7 cohort, of which 4
  19. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
    April 01, 2007 - Analysis and Interpretation Analysis and interpretation of registry data begin with answering a series … Analysis of registry outcomes first requires an analysis of the completeness of data collection and data … plan that contains sufficient detail to explain the main focus and proposed methods of analysisAnalysis • Accepted analytic techniques are used; these may be augmented by new or novel approaches … Analysis • Loss to followup is characterized at key stages during the conduct of the study.
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/reporting.ppt
    September 01, 2009 - A systematic review and meta-analysis of randomized placebo-controlled trials. … Methods: Additional Analyses Additional analysis, such as a subgroup analysis or a meta-regression, should … Systematic review and meta-analysis of randomised controlled trials. BMJ 2005;331:313-21. … Meta-analysis: chondroitin for osteoarthritis of the knee or hip. … A systematic review and meta-analysis of randomized placebo-controlled trials.

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