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441. C-Diff-Infections-Surveillance-140925 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
     January 01, 2014 - , but not with strict intention-to-treat analysis. … A survival analysis. Ann Intern Med. 2007;147(4):224- 33.17638714 4. … (15.4% vs. 25.3%, P=0.005) and the per-protocol analysis (13.3% vs. 24.0%, P=0.004). … Weiss et 2012 Safety analysis A total of 728 adults 116 healthy N/A; tolerability, In this safety analysis … , but not with strict intention-to-treat analysis.

442. Colorectal-Surgery-Preparation Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_executive.pdf
     April 01, 2014 - We used both pairwise and network meta-analysis. … OMBP Versus No OMBP Eighteen RCTs and seven NRCSs contributed information to the main analysis. … These findings, in conjunction with the wide CrIs observed in the overall meta-analysis, support the … Using network meta-analysis we compared “OMBP with or without enema,” “enema,” and “no preparation” … We did not attempt a meta-analysis because of the substantial diversity in outcome definitions, and

443. S131 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s131.pdf
     October 01, 2007 - Data Source of Empirical Analysis The study cohort was drawn from a population of seniors age 65 years … Cohort 5—Subgroup Analysis of Typical Trial-Eligible Subjects We restricted our final analysis to subjects … In the most restricted analysis (cohort 5), the unadjusted RR was 0.72. … An analysis of the exclusion criteria used in observational pharmacoepidemiological studies. … Subgroup analysis in randomized controlled trials: im- portance, indications, and interpretation.

444. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - They had serious errors in design, analysis, or reporting; large amounts of missing information; or … A descriptive analysis of minor depression. … Screening and case-finding instruments for depression: a meta-analysis. … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses … "[Publication Type] OR "meta-analysis as topic"[MeSH Terms] OR "meta-analysis"[tiab] OR "meta-analyses

445. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
     February 01, 2013 - Meta-Analysis or Individual Patient Data Analysis Across RCTs? … Meta-Analysis or Individual Patient Data Analysis Across RCTs? … Multivariable analysis. … : Observational Meta-analysis of Observational Studies Yes META-ANALYSIS: OBSERVATIONAL STUDIES … Meta-Analysis of RCTs If a new RCT is not feasible, then a meta-analysis of existing RCTs may provide

446. Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
     December 01, 2017 - Analysis of results for the intention-to-treat population did not find improvement, but analysis of … A responder analysis (proportion of patients who achieved the minimum important difference) favored … Compared with sham treatment, the intention-to-treat analysis in a single RCT suggests that BT had no

447. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
     September 01, 2014 - Please consider revising the analysis accordingly. ES2: Simva vs. … ES6: We agree and have revised this section and the analysis accordingly: rosuvastatin is evaluated … This is also the finding of a meta- analysis by Costanzo et al. (J. Am. Coll. … We suggest that the authors consider revising the analysis accordingly. … For instance, where possible paired analysis would be chosen.

448. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - Eligibility criteria included English language studies evaluating SNP analysis of human populations, … The SNP analysis had to be across more than one gene, commercially available (or close to this), and … There would be value in applying decision analysis methods. … Screening for prostate cancer: Systematic review and meta-analysis of randomised controlled trials. … Receiver operating characteristic analysis: a primer. Acad Radiol. 2005;12(7):909-16.

449. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
     January 01, 2015 - However, in 2013, a re- analysis of the pivotal trial substantially reduced the FDA’s concern leading … , or state that the individuals included in the analysis were similar to those lost to follow up or … Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177-88. 31. … Random- Effects Meta-analysis of Inconsistent Effects: A Time for Change. … Bias in meta-analysis detected by a simple, graphical test.

450. Colorectal-Cancer-Staging Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
     September 01, 2014 - We performed meta- analysis wherever appropriate and possible. … We explored possible causes of heterogeneity with subgroup analysis. … We pooled the results from both studies in a random-effects meta-analysis. … A unification of models for meta-analysis of diagnostic accuracy studies. … Diagnostic precision of CT in local staging of colon cancers: a meta-analysis.

451. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
     February 22, 2012 - : adjustment for potential confounders and intention-to-treat analysis • Intervention studies will … In addition, intention-to-treat analysis is used for RCTs. Fair. … Intention-to-treat analysis has been done for RCTs. … Schwarzer G. meta: Meta-Analysis with R (version 1.6-1). 2011. http://CRAN.R-project.org/. … Fixed- and random-effects models in meta-analysis. Psychol Meth. 1998;3(4):486-504.

452. hemangioma-protocol-141223 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_research-protocol.pdf
     December 23, 2014 - The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta- analysis … the analysis, reporting, and claim of subgroup effects in randomized trials. … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report … Propranolol is an effective treatment for airway haemangiomas: a critical analysis and meta-analysis

453. Mental-Illness-Heart Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
     April 01, 2013 - We then determined the feasibility of completing a quantitative synthesis (i.e., meta-analysis). … A systematic review and pooled analysis. J Psychopharmacol. 2010;24(4 Suppl):69-80. … An analysis of the definitions of mental illness used in state parity laws. … Quantifying heterogeneity in a meta- analysis. Statistics in Medicine. 2002;21(11):1539-58. … Value-of-Information Analysis for Patient-Centered Outcomes Research Prioritization.

454. Template for Reports Developed (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
     July 01, 2011 - If the original report includes a meta-analysis, a quantitative signal is considered. … A survival analysis. Ann Intern Med 2007;147(4):224-233. 20. … Cumulative meta-analysis of therapeutic trials for myocardial infarction. … Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care. … Cumulative meta-analysis: a consideration of indicators of sufficiency and stability.

455. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
     February 24, 2016 - of the performance of tests or clinical features ‘compared to synovial fluid analysis’. … However, at various times throughout the analysis, data are included that use clinical criteria as … Unfortunately, and partly due to the difficulties with crystal analysis, study participants do not … of having neither so many or so few features of gout that SF analysis was unnecessary. … These findings tend to support not undertaking MSU analysis in the primary care setting .

456. Decision and Simulation Modeling in Systematic Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-decision-simulation-modeling/research
     November 01, 2017 - assumptions, definition and presentation of parameters, outcomes to incorporate into the model, model analysis … overview of models and describes the differences and synergies between systematic reviews and decision analysis … Conclusions We suggest a process for deciding when conducting a decision analysis in conjunction with

457. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - A published network meta-analysis of 212 trials found that clozapine was superior to other oral SGAs … This analysis found that all of the drugs included were superior to placebo. … Analysis of age subgroups did not find differences for comparisons of olanzapine with risperidone. … Cognitive remediation for negative symptoms of schizophrenia: A network meta- analysis. … A meta-analysis of controlled research on social skills training for schizophrenia.

458. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - We will deposit data used in a meta-analysis into the Systematic Review Data Repository (SRDR). … We anticipate performing a meta-analysis to describe the effects of treatment decisions on outcomes … The specific meta-analysis or meta-regression will depend on the data available. … for variables where it makes sense to do so, or subgroup analysis (with random effects meta-analysis … Technical Experts do not do analysis of any kind nor do they contribute to the writing of the report

459. S116 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - To insure that the IV analysis was not biased by case-mix differences between physi- cians, we examined … between long-acting benzodiazepine prescribing and APM prefer- ence was no longer significant when the analysis … We restricted the analysis to just APM initiators to guard against selection bias among prevalent users … Longitudinal data analysis for discrete and con- tinuous outcomes. … Basic methods for sensitivity analysis of biases. Int J Epidemiol. 1996;25:1107–1116. 17.

460. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis—An Update of the 2006 Report. (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
     October 01, 2011 - The sentence in question in the Executive Summary is referring to the finding in meta-analysis that … We revised to clarify (page 20, starting line 26): “A meta-analysis of 41 randomized trials found no … Patrick du Souich Results In page 52, based on the meta-analysis of Wandel et al.(1)it is stated … We did not identify a meta-analysis restricted to low- dose aspirin. … Each category of analgesics provided a detailed analysis.